Best TWAS P=1.07e-07 · Best GWAS P=7.28e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | GAR1 | 0.22 | 0.08 | lasso | 3 | 0.04 | 2.9e-02 | 5.1 | -5.3 | 1.4e-07 | -0.94 | 0.01 | 0.83 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | GAR1 | 0.04 | 0.06 | lasso | 2 | 0.06 | 8.1e-07 | 5.4 | 5.3 | 1.1e-07 | 0.99 | 0.00 | 1.00 | TRUE |
3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | GAR1 | 0.10 | 0.09 | lasso | 2 | 0.07 | 6.8e-04 | 5.4 | -5.3 | 1.1e-07 | -0.99 | 0.00 | 0.95 | FALSE |