[Hub]/) : Traits : Trunk fat-free mass : ← →

chr4:105,373,669-107,092,169

Best TWAS P=8.11e-27 · Best GWAS P=2.49e-31 conditioned to 4.56e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Esophagus Gastroesophageal Junction	PPA2	0.29	0.15	lasso	5	0.14	8.8e-06	-11.2	-10.7	8.1e-27	0.81	0.05	0.91	TRUE
8	GTEx	Esophagus Mucosa	PPA2	0.18	0.06	enet	14	0.12	2.5e-08	8.8	-9.7	2.3e-22	0.68	0.12	0.87	FALSE
5	GTEx	Brain Cortex	PPA2	0.14	0.09	lasso	9	0.09	1.6e-03	-9.0	-9.1	7.6e-20	0.79	0.06	0.58	FALSE
12	GTEx	Ovary	PPA2	0.18	0.10	lasso	3	0.14	2.2e-04	-7.7	-9.0	3.3e-19	0.72	0.06	0.67	FALSE
3	GTEx	Artery Aorta	PPA2	0.11	-0.01	enet	24	0.01	1.6e-01	-11.2	-8.4	4.5e-17	0.58	0.07	0.35	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	PPA2	0.04	0.02	blup	84	0.04	6.1e-05	-9.0	-8.3	1.1e-16	0.74	0.14	0.65	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PPA2	0.08	0.03	bslmm	429	0.04	2.2e-05	-7.1	-7.7	1.3e-14	0.61	0.08	0.88	FALSE
6	GTEx	Cells Transformed fibroblasts	PPA2	0.11	0.03	lasso	3	0.01	6.5e-02	-7.0	-7.6	2.1e-14	0.59	0.41	0.11	FALSE
11	GTEx	Nerve Tibial	PPA2	0.13	0.07	enet	23	0.07	2.1e-05	-7.7	-7.5	9.6e-14	0.63	0.48	0.28	FALSE
9	GTEx	Heart Atrial Appendage	PPA2	0.15	0.05	lasso	7	0.06	7.4e-04	-9.3	-7.3	2.2e-13	0.70	0.24	0.38	FALSE
13	GTEx	Skin Sun Exposed Lower leg	TET2	0.09	0.01	enet	18	0.02	3.6e-03	-11.5	-7.3	3.1e-13	0.58	0.02	0.89	FALSE
10	GTEx	Muscle Skeletal	PPA2	0.19	0.06	enet	28	0.11	8.7e-11	-9.0	-6.5	7.3e-11	0.67	0.80	0.19	FALSE
4	GTEx	Brain Cerebellum	PPA2	0.22	0.01	lasso	4	0.03	3.7e-02	-7.7	-6.2	4.0e-10	0.55	0.09	0.15	FALSE
14	GTEx	Thyroid	PPA2	0.22	0.01	enet	18	0.12	2.9e-09	6.0	-5.8	6.0e-09	0.50	0.75	0.05	FALSE
2	GTEx	Adipose Subcutaneous	PPA2	0.15	0.02	enet	36	0.06	7.0e-06	4.7	-5.6	2.7e-08	0.38	0.27	0.09	FALSE
16	YFS	Blood	PPA2	0.22	0.05	lasso	19	0.12	9.7e-38	-3.4	5.5	4.8e-08	-0.40	1.00	0.00	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	PPA2	0.32	0.38	lasso	2	0.38	1.1e-51	4.6	-5.2	1.8e-07	0.42	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PPA2	0.29	0.01	blup	84	0.10	4.3e-06	-5.9	-5.1	2.8e-07	0.42	0.13	0.12	FALSE