Best TWAS P=1.62e-10 · Best GWAS P=1.3e-11 conditioned to 3.2e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ELOVL7 | 0.04 | 0.03 | blup | 355 | 0.03 | 0.00014 | 4.3 | -5.2 | 2.0e-07 | 0.52 | 0.54 | 0.39 | FALSE |
2 | GTEx | Brain Cerebellar Hemisphere | GNL3LP1 | 0.21 | 0.17 | lasso | 10 | 0.12 | 0.00062 | 5.2 | 5.3 | 1.4e-07 | -0.57 | 0.42 | 0.23 | FALSE |
3 | GTEx | Brain Hippocampus | GNL3LP1 | 0.51 | 0.04 | enet | 2 | 0.14 | 0.00041 | 5.1 | 5.1 | 2.9e-07 | -0.50 | 0.07 | 0.10 | FALSE |
4 | GTEx | Pancreas | SMIM15 | 0.10 | 0.03 | enet | 22 | 0.05 | 0.00383 | -4.5 | 6.4 | 1.6e-10 | -0.49 | 0.07 | 0.25 | TRUE |