Best TWAS P=2.64e-08 · Best GWAS P=3.51e-08 conditioned to 0.227
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | RP11-57H14.2 | 0.20 | 0.19 | lasso | 2 | 0.18 | 2.3e-11 | 5.4 | 5.6 | 2.6e-08 | 0.89 | 0 | 1.00 | TRUE |
| 2 | GTEx | Heart Left Ventricle | RP11-57H14.2 | 0.19 | 0.13 | lasso | 4 | 0.11 | 2.9e-06 | 5.4 | 5.4 | 6.6e-08 | 0.83 | 0 | 0.99 | FALSE |
| 3 | GTEx | Lung | RP11-57H14.2 | 0.12 | 0.14 | lasso | 3 | 0.12 | 2.6e-09 | 5.4 | 5.1 | 2.9e-07 | 0.84 | 0 | 1.00 | FALSE |
| 4 | GTEx | Thyroid | RP11-57H14.2 | 0.14 | 0.10 | lasso | 1 | 0.09 | 1.8e-07 | 5.4 | 5.4 | 5.9e-08 | 0.84 | 0 | 1.00 | FALSE |