Best TWAS P=4.64e-08 · Best GWAS P=6.83e-09 conditioned to 0.0173
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | SP1 | 0.17 | 0.12 | lasso | 4 | 0.12 | 8.6e-05 | 3.8 | 5.2 | 2.5e-07 | -0.31 | 0.16 | 0.60 | FALSE |
| 2 | METSIM | Adipose | SOAT2 | 0.03 | 0.06 | lasso | 1 | 0.05 | 1.5e-08 | 5.1 | -5.1 | 2.7e-07 | 0.15 | 0.07 | 0.93 | FALSE |
| 3 | METSIM | Adipose | SP7 | 0.03 | 0.02 | lasso | 2 | 0.01 | 6.1e-03 | 5.1 | -5.5 | 4.6e-08 | 0.15 | 0.07 | 0.70 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PRR13 | 0.07 | 0.04 | blup | 28 | 0.05 | 4.7e-06 | 3.2 | -5.2 | 2.0e-07 | 0.60 | 0.37 | 0.24 | TRUE |