[Hub]/) : Traits : Trunk predicted mass :

chr12:55,633,142-58,222,672

Best TWAS P=4.7e-17 · Best GWAS P=1.31e-16 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CNPY2 0.06 0.05 lasso 8 0.05 2.3e-06 5.5 -5.6 1.9e-08 0.00 0.99 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex PAN2 0.05 0.07 lasso 3 0.06 5.4e-08 5.7 5.7 9.0e-09 0.01 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex PRIM1 0.31 0.24 enet 7 0.24 1.1e-28 -8.3 8.4 4.7e-17 -1.00 0.00 1.00 TRUE
4 CommonMind Brain Pre-frontal Cortex RPS26 0.48 0.62 lasso 5 0.63 5.9e-99 -6.3 -6.2 6.5e-10 -0.04 0.99 0.01 FALSE
5 GTEx Adipose Subcutaneous STAT2 0.11 0.07 enet 24 0.05 4.9e-05 5.6 -5.1 2.7e-07 -0.11 0.91 0.00 TRUE
6 GTEx Adipose Subcutaneous RP11-977G19.11 0.12 0.10 lasso 7 0.09 7.5e-08 5.6 -5.3 1.2e-07 0.01 1.00 0.00 FALSE
7 GTEx Adrenal Gland RP11-977G19.11 0.19 0.16 lasso 15 0.09 3.9e-04 5.5 -5.6 2.2e-08 0.00 0.86 0.01 FALSE
8 GTEx Artery Aorta SUOX 0.36 0.30 lasso 7 0.35 3.8e-20 -5.8 5.2 2.3e-07 0.05 1.00 0.00 FALSE
9 GTEx Artery Aorta RP11-977G19.11 0.26 0.28 lasso 14 0.28 5.3e-16 5.7 -5.7 9.0e-09 -0.01 1.00 0.00 FALSE
10 GTEx Artery Aorta CNPY2 0.13 0.03 lasso 14 0.03 5.9e-03 2.7 5.1 2.7e-07 0.01 0.19 0.04 FALSE
11 GTEx Artery Coronary RP11-977G19.11 0.24 0.14 lasso 13 0.08 1.2e-03 5.5 -5.9 4.6e-09 0.00 0.54 0.02 FALSE
12 GTEx Artery Tibial STAT6 0.08 0.03 enet 4 0.02 1.3e-02 -6.0 -6.2 5.6e-10 0.19 0.29 0.05 TRUE
13 GTEx Artery Tibial RPS26 0.07 0.02 enet 5 0.01 3.5e-02 -6.3 -6.1 9.1e-10 -0.03 0.24 0.16 FALSE
14 GTEx Artery Tibial RP11-977G19.11 0.16 0.18 lasso 12 0.18 6.1e-14 5.7 -5.7 9.0e-09 -0.01 1.00 0.00 FALSE
15 GTEx Brain Caudate basal ganglia RP11-977G19.11 0.31 0.25 lasso 5 0.28 1.2e-08 5.7 -6.2 6.0e-10 -0.01 0.91 0.01 TRUE
16 GTEx Brain Cerebellum HSD17B6 0.31 0.27 lasso 5 0.29 3.2e-09 -5.6 -5.1 2.8e-07 0.70 0.09 0.85 FALSE
17 GTEx Brain Cerebellum SUOX 0.24 0.20 lasso 6 0.20 1.2e-06 -5.8 5.2 1.8e-07 0.04 0.08 0.86 FALSE
18 GTEx Brain Cerebellum RP11-977G19.11 0.17 0.19 lasso 14 0.18 5.4e-06 5.7 -5.7 1.2e-08 -0.01 0.65 0.02 FALSE
19 GTEx Brain Cortex SUOX 0.16 0.11 lasso 4 0.10 1.1e-03 -5.8 6.0 2.3e-09 0.03 0.07 0.26 FALSE
20 GTEx Brain Hypothalamus RP11-977G19.11 0.32 0.20 lasso 6 0.23 4.4e-06 5.4 -5.6 1.7e-08 -0.02 0.77 0.02 FALSE
21 GTEx Brain Nucleus accumbens basal ganglia RP11-977G19.11 0.30 0.12 lasso 10 0.08 4.6e-03 5.6 -5.4 6.1e-08 -0.02 0.27 0.05 FALSE
22 GTEx Brain Putamen basal ganglia RP11-973D8.4 0.18 0.21 lasso 1 0.14 4.3e-04 5.4 -5.4 5.2e-08 -0.03 0.17 0.05 FALSE
23 GTEx Breast Mammary Tissue RPS26 0.29 0.05 enet 37 0.12 9.4e-07 -6.3 -7.6 2.3e-14 -0.02 0.22 0.77 FALSE
24 GTEx Breast Mammary Tissue RP11-977G19.11 0.11 0.08 lasso 8 0.04 2.5e-03 5.5 -5.5 5.0e-08 -0.02 0.30 0.04 FALSE
25 GTEx Breast Mammary Tissue (Female) RPS26 0.20 0.11 lasso 3 0.10 6.6e-04 -5.8 -7.9 3.0e-15 -0.01 0.01 0.87 TRUE
26 GTEx Cells Transformed fibroblasts PAN2 0.09 0.07 lasso 4 0.05 1.7e-04 5.6 6.0 2.4e-09 -0.03 0.90 0.00 FALSE
27 GTEx Cells Transformed fibroblasts RP11-977G19.11 0.11 0.07 enet 22 0.05 9.5e-05 5.5 -5.5 3.7e-08 -0.01 0.99 0.00 FALSE
28 GTEx Colon Sigmoid SUOX 0.23 0.18 lasso 4 0.15 7.9e-06 -5.8 5.8 6.6e-09 0.04 0.38 0.57 FALSE
29 GTEx Colon Sigmoid RP11-977G19.11 0.22 0.00 enet 33 0.04 1.5e-02 5.7 -6.8 1.4e-11 0.31 0.11 0.17 FALSE
30 GTEx Colon Transverse RP11-977G19.11 0.18 0.05 lasso 2 0.00 1.9e-01 5.5 -5.6 2.7e-08 0.00 0.13 0.04 FALSE
31 GTEx Esophagus Gastroesophageal Junction SUOX 0.20 0.16 lasso 5 0.19 2.7e-07 -5.8 6.2 5.7e-10 0.03 0.66 0.28 FALSE
32 GTEx Esophagus Gastroesophageal Junction RP11-977G19.11 0.18 0.14 lasso 13 0.07 2.0e-03 5.7 -5.7 9.0e-09 -0.01 0.65 0.02 FALSE
33 GTEx Esophagus Mucosa RP11-977G19.11 0.07 0.09 lasso 1 0.07 1.5e-05 5.5 -5.5 4.8e-08 0.00 0.95 0.00 FALSE
34 GTEx Esophagus Muscularis SUOX 0.24 0.19 enet 16 0.15 2.3e-09 -5.8 5.8 8.6e-09 0.05 0.99 0.01 FALSE
35 GTEx Heart Atrial Appendage SUOX 0.09 0.10 enet 8 0.09 1.1e-04 -6.3 6.1 1.4e-09 0.02 0.14 0.63 TRUE
36 GTEx Liver DGKA 0.33 0.03 lasso 15 0.13 1.4e-04 5.4 5.1 3.1e-07 0.08 0.09 0.05 FALSE
37 GTEx Liver STAT2 0.32 0.17 lasso 13 0.14 9.9e-05 5.7 5.8 8.7e-09 0.01 0.82 0.01 FALSE
38 GTEx Lung RP11-977G19.11 0.07 0.03 lasso 11 0.04 5.1e-04 5.5 -5.7 1.2e-08 -0.01 0.79 0.01 FALSE
39 GTEx Lung CNPY2 0.05 0.03 lasso 4 0.00 1.7e-01 5.6 5.6 2.5e-08 -0.02 0.34 0.03 FALSE
40 GTEx Muscle Skeletal RAB5B 0.29 0.32 lasso 4 0.33 1.3e-33 -6.3 6.5 9.9e-11 0.02 0.99 0.01 FALSE
41 GTEx Muscle Skeletal SUOX 0.11 0.04 lasso 7 0.04 4.4e-05 -5.8 6.5 6.6e-11 0.02 0.29 0.63 TRUE
42 GTEx Muscle Skeletal AC034102.1 0.28 0.31 lasso 4 0.31 2.3e-31 -6.3 6.5 9.5e-11 0.02 0.99 0.01 FALSE
43 GTEx Nerve Tibial IL23A 0.06 0.08 lasso 10 0.07 1.6e-05 5.6 5.6 2.0e-08 -0.02 0.87 0.00 FALSE
44 GTEx Nerve Tibial STAT2 0.08 0.05 lasso 3 0.03 5.0e-03 5.6 -5.5 2.9e-08 0.02 0.37 0.04 FALSE
45 GTEx Nerve Tibial RPS26 0.12 0.09 enet 7 0.11 3.0e-08 -6.0 -5.8 6.9e-09 -0.05 0.95 0.04 FALSE
46 GTEx Nerve Tibial RP11-977G19.11 0.15 0.18 enet 23 0.20 7.7e-14 5.5 -5.5 4.1e-08 -0.01 1.00 0.00 FALSE
47 GTEx Nerve Tibial CNPY2 0.07 0.00 enet 21 0.00 3.2e-01 -6.0 5.9 4.0e-09 0.05 0.10 0.06 FALSE
48 GTEx Pancreas IL23A 0.23 0.01 lasso 13 0.04 1.1e-02 5.7 5.8 8.7e-09 0.01 1.00 0.00 FALSE
49 GTEx Pituitary IL23A 0.27 0.11 lasso 9 0.12 8.0e-04 5.5 5.3 1.0e-07 0.01 0.22 0.06 FALSE
50 GTEx Pituitary RP11-977G19.11 0.47 0.40 lasso 14 0.40 4.5e-11 5.5 -5.9 3.5e-09 0.00 0.99 0.00 FALSE
51 GTEx Pituitary CNPY2 0.32 0.19 lasso 11 0.12 6.8e-04 5.7 5.7 9.0e-09 0.01 0.29 0.06 FALSE
52 GTEx Prostate SUOX 0.22 0.04 enet 11 0.05 2.3e-02 -5.8 6.4 1.6e-10 0.02 0.10 0.38 FALSE
53 GTEx Skin Not Sun Exposed Suprapubic SUOX 0.10 0.14 lasso 2 0.12 2.5e-07 -5.8 5.8 7.6e-09 0.03 0.49 0.44 FALSE
54 GTEx Skin Sun Exposed Lower leg SUOX 0.23 0.30 lasso 3 0.29 1.9e-24 -5.8 6.0 2.0e-09 0.03 1.00 0.00 FALSE
55 GTEx Skin Sun Exposed Lower leg RP11-977G19.11 0.15 0.09 lasso 11 0.08 1.9e-07 5.5 -5.4 8.2e-08 -0.02 1.00 0.00 FALSE
56 GTEx Skin Sun Exposed Lower leg CNPY2 0.10 0.08 lasso 5 0.08 5.9e-07 5.7 5.8 6.8e-09 0.01 0.96 0.01 FALSE
57 GTEx Spleen SUOX 0.34 0.31 enet 15 0.28 5.4e-08 -5.8 5.4 6.8e-08 0.03 0.14 0.76 FALSE
58 GTEx Stomach SUOX 0.15 0.17 enet 8 0.09 6.7e-05 -5.8 5.5 4.8e-08 0.03 0.68 0.24 FALSE
59 GTEx Stomach RPS26 0.16 0.08 enet 5 0.05 1.8e-03 -5.8 -5.7 1.4e-08 -0.03 0.11 0.46 FALSE
60 GTEx Testis SUOX 0.27 0.18 lasso 14 0.18 1.4e-08 -5.8 6.4 1.1e-10 0.03 0.74 0.25 FALSE
61 GTEx Thyroid IL23A 0.07 0.04 lasso 10 0.00 1.9e-01 5.7 5.7 9.0e-09 0.01 0.39 0.03 FALSE
62 GTEx Thyroid SUOX 0.37 0.40 lasso 7 0.38 5.4e-31 -5.8 6.0 2.2e-09 0.03 1.00 0.00 FALSE
63 GTEx Thyroid RP11-977G19.11 0.16 0.11 enet 20 0.13 3.5e-10 5.5 -6.5 7.6e-11 -0.02 1.00 0.00 FALSE
64 GTEx Thyroid CNPY2 0.06 0.02 lasso 10 0.02 2.1e-02 5.4 5.4 7.3e-08 0.01 0.58 0.02 FALSE
65 GTEx Whole Blood RPS26 0.05 0.05 lasso 1 0.05 3.4e-05 -5.8 -5.8 7.2e-09 -0.03 0.23 0.68 FALSE
66 METSIM Adipose IKZF4 0.04 0.04 enet 3 0.04 1.0e-06 -6.1 -6.2 5.3e-10 -0.03 0.98 0.01 FALSE
67 METSIM Adipose RPS26 0.30 0.40 lasso 5 0.41 7.2e-66 -6.2 -6.3 3.0e-10 -0.03 0.99 0.01 FALSE
68 NTR Blood OBFC2B 0.01 0.00 bslmm 248 0.00 3.6e-02 2.0 -5.1 2.8e-07 0.00 0.05 0.02 FALSE
69 ROSMAP Brain Pre-frontal Cortex NABP2 0.12 0.12 lasso 4 0.13 2.7e-16 5.7 5.9 3.6e-09 0.00 1.00 0.00 FALSE
70 YFS Blood CNPY2 0.02 0.02 lasso 1 0.02 5.8e-07 5.4 5.4 5.6e-08 0.02 0.99 0.00 FALSE
71 YFS Blood SUOX 0.11 0.09 bslmm 269 0.09 3.4e-27 -5.8 5.5 3.4e-08 0.02 1.00 0.00 FALSE
72 The Cancer Genome Atlas Bladder Urothelial Carcinoma RPS26 0.14 0.22 lasso 2 0.23 4.8e-19 -6.2 -6.3 3.0e-10 -0.03 0.22 0.78 FALSE
73 The Cancer Genome Atlas Breast Invasive Carcinoma RPS26 0.30 0.44 enet 10 0.45 5.2e-104 -6.3 -6.4 1.4e-10 -0.04 0.17 0.83 FALSE
74 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma RPS26 0.23 0.40 lasso 2 0.39 1.5e-20 -6.3 -6.5 9.9e-11 -0.04 0.16 0.84 FALSE
75 The Cancer Genome Atlas Colon Adenocarcinoma RPS26 0.43 0.48 lasso 4 0.47 1.8e-30 -6.3 -6.5 6.1e-11 -0.04 0.17 0.83 FALSE
76 The Cancer Genome Atlas Esophageal Carcinoma RPS26 0.19 0.13 lasso 5 0.11 2.4e-04 -6.3 -6.4 1.2e-10 -0.04 0.02 0.95 FALSE
77 The Cancer Genome Atlas Glioblastoma Multiforme PAN2 0.08 0.04 blup 31 0.03 4.4e-02 5.4 5.8 8.0e-09 0.02 0.01 0.57 FALSE
78 The Cancer Genome Atlas Glioblastoma Multiforme RPS26 0.41 0.38 enet 9 0.39 7.9e-13 -6.2 -6.3 2.3e-10 -0.03 0.20 0.80 FALSE
79 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RPS26 0.17 0.29 lasso 4 0.29 6.2e-33 -6.2 -6.3 2.4e-10 -0.03 0.24 0.76 FALSE
80 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPS26 0.50 0.45 enet 13 0.52 1.4e-67 -6.2 -5.4 5.3e-08 -0.05 0.30 0.70 FALSE
81 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma RPS26 0.27 0.38 enet 8 0.40 5.0e-24 -6.3 -6.3 2.6e-10 -0.04 0.20 0.80 FALSE
82 The Cancer Genome Atlas Brain Lower Grade Glioma IL23A 0.03 0.04 lasso 7 0.04 2.9e-05 5.4 5.4 5.3e-08 0.00 0.01 0.98 FALSE
83 The Cancer Genome Atlas Brain Lower Grade Glioma RPS26 0.31 0.53 enet 8 0.55 1.7e-74 -6.3 -6.4 2.0e-10 -0.03 0.22 0.78 FALSE
84 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RPS26 0.18 0.31 lasso 2 0.29 3.9e-14 -6.3 -6.3 3.3e-10 -0.04 0.19 0.81 FALSE
85 The Cancer Genome Atlas Lung Adenocarcinoma RAB5B 0.03 0.02 enet 7 0.02 4.3e-03 -6.3 -6.0 2.4e-09 -0.03 0.02 0.26 FALSE
86 The Cancer Genome Atlas Lung Adenocarcinoma RPS26 0.26 0.45 enet 9 0.47 3.6e-61 -6.3 -6.5 9.7e-11 -0.03 0.19 0.81 FALSE
87 The Cancer Genome Atlas Lung Adenocarcinoma STAT2 0.02 0.02 blup 21 0.01 9.6e-03 5.4 5.6 2.4e-08 0.01 0.01 0.86 FALSE
88 The Cancer Genome Atlas Lung Squamous Cell Carcinoma RPS26 0.22 0.31 lasso 3 0.31 1.6e-35 -6.3 -6.6 5.6e-11 -0.04 0.17 0.83 FALSE
89 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma RPS26 0.30 0.20 lasso 4 0.24 3.9e-16 -6.3 -6.7 2.7e-11 -0.04 0.08 0.92 FALSE
90 The Cancer Genome Atlas Pancreatic Adenocarcinoma ESYT1 0.16 0.02 blup 33 0.05 5.5e-03 1.6 -5.4 5.9e-08 0.03 0.01 0.67 TRUE
91 The Cancer Genome Atlas Pancreatic Adenocarcinoma RPS26 0.36 0.44 lasso 7 0.42 2.4e-19 -6.2 -6.2 7.3e-10 -0.03 0.31 0.69 FALSE
92 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma RPS26 0.47 0.43 lasso 2 0.44 3.2e-19 -5.8 -6.1 1.3e-09 -0.03 0.33 0.67 FALSE
93 The Cancer Genome Atlas Prostate Adenocarcinoma COQ10A 0.03 0.03 lasso 2 0.03 9.1e-04 5.5 -5.5 2.9e-08 0.00 0.01 0.92 FALSE
94 The Cancer Genome Atlas Prostate Adenocarcinoma RPS26 0.33 0.52 enet 9 0.54 5.6e-66 -6.3 -6.4 1.8e-10 -0.03 0.18 0.82 FALSE
95 The Cancer Genome Atlas Rectum Adenocarcinoma RPS26 0.24 0.18 lasso 2 0.20 1.9e-05 -6.3 -6.2 5.0e-10 -0.04 0.05 0.54 FALSE
96 The Cancer Genome Atlas Soft Tissue Sarcoma RPS26 0.23 0.31 lasso 3 0.30 2.4e-18 -6.3 -6.4 1.7e-10 -0.04 0.17 0.83 FALSE
97 The Cancer Genome Atlas Skin Cutaneous Melanoma RPS26 0.28 0.15 lasso 2 0.17 3.0e-05 -6.2 -6.3 3.7e-10 -0.03 0.02 0.94 FALSE
98 The Cancer Genome Atlas Stomach Adenocarcinoma RPS26 0.19 0.32 lasso 5 0.34 2.0e-25 -6.2 -6.4 1.4e-10 -0.03 0.26 0.74 FALSE
99 The Cancer Genome Atlas Testicular Germ Cell Tumors RPS26 0.46 0.64 lasso 4 0.65 8.5e-30 -6.3 -6.6 5.2e-11 -0.03 0.17 0.83 FALSE
100 The Cancer Genome Atlas Thyroid Carcinoma IL23A 0.03 0.03 blup 22 0.02 1.8e-03 5.4 5.4 6.1e-08 0.02 0.01 0.79 FALSE
101 The Cancer Genome Atlas Thyroid Carcinoma RPS26 0.33 0.51 enet 19 0.50 7.3e-56 -6.3 -5.5 4.0e-08 -0.04 0.18 0.82 FALSE
102 The Cancer Genome Atlas Thyroid Carcinoma STAT6 0.04 0.01 blup 47 0.01 2.3e-02 -4.0 -5.4 7.3e-08 0.02 0.06 0.29 FALSE
103 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma RPS26 0.17 0.19 lasso 4 0.18 1.3e-05 -6.3 -6.2 5.5e-10 -0.03 0.04 0.93 FALSE