[Hub]/) : Traits : Trunk predicted mass : ← →

chr12:101,575,652-103,148,974

Best TWAS P=2.66e-09 · Best GWAS P=6.11e-17 conditioned to 4.28e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CCDC53 0.21 0.15 blup 448 0.19 2.4e-22 3.7 -5.5 3.9e-08 -0.04 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous CCDC53 0.14 0.16 lasso 13 0.15 1.5e-12 5.8 -5.1 3.1e-07 0.06 1.00 0.00 FALSE
3 GTEx Cells Transformed fibroblasts CCDC53 0.10 0.18 lasso 1 0.17 1.5e-12 5.7 -5.7 1.2e-08 0.13 1.00 0.00 FALSE
4 GTEx Esophagus Mucosa CCDC53 0.31 0.41 enet 17 0.43 1.0e-30 3.8 -5.2 2.5e-07 0.04 1.00 0.00 FALSE
5 GTEx Heart Left Ventricle CCDC53 0.14 0.20 lasso 4 0.18 9.6e-10 5.7 -5.3 1.0e-07 0.09 1.00 0.00 FALSE
6 GTEx Lung CCDC53 0.12 0.10 lasso 3 0.11 6.8e-09 5.7 -5.2 1.5e-07 0.10 1.00 0.00 FALSE
7 GTEx Spleen CCDC53 0.25 0.19 lasso 11 0.16 5.8e-05 5.7 -5.8 7.3e-09 0.14 0.50 0.07 TRUE
8 GTEx Thyroid CCDC53 0.15 0.12 lasso 6 0.12 4.3e-09 5.7 -5.2 1.9e-07 0.09 1.00 0.00 FALSE
9 METSIM Adipose DRAM1 0.12 0.03 enet 24 0.08 1.1e-12 4.2 5.8 7.3e-09 -0.10 1.00 0.00 FALSE
10 YFS Blood DRAM1 0.33 0.13 enet 101 0.19 1.6e-58 5.6 6.0 2.7e-09 -0.20 1.00 0.00 TRUE
11 The Cancer Genome Atlas Colon Adenocarcinoma CCDC53 0.07 0.07 blup 55 0.06 1.3e-04 4.9 -5.4 8.6e-08 0.18 0.93 0.00 FALSE
12 The Cancer Genome Atlas Esophageal Carcinoma CCDC53 0.14 0.08 blup 50 0.08 1.8e-03 5.7 -5.4 7.0e-08 0.15 0.14 0.06 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC53 0.08 0.09 lasso 3 0.09 4.9e-10 5.7 -5.1 3.1e-07 0.09 1.00 0.00 FALSE
14 The Cancer Genome Atlas Stomach Adenocarcinoma CCDC53 0.04 0.07 lasso 4 0.06 2.1e-05 5.7 -5.7 1.3e-08 0.13 0.83 0.01 FALSE