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Traits
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Trunk predicted mass
:
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→
chr12:93,110,493-94,675,142
Best TWAS P=7.77e-23 · Best GWAS P=1.48e-51 conditioned to 1.97e-24
93.2M
93.4M
93.6M
93.8M
94M
94.2M
94.4M
94.6M
0
10
20
30
40
50
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Breast Mammary Tissue (Male)
MRPL42
0.21
-0.01
lasso
2
-0.01
6.0e-01
10.0
-9.8
7.8e-23
-0.48
0.05
0.06
TRUE
3
YFS
Blood
SOCS2
0.06
0.04
bslmm
444
0.04
1.7e-12
7.4
8.7
3.1e-18
0.01
1.00
0.00
TRUE
4
YFS
Blood
UBE2N
0.02
0.00
bslmm
424
0.01
3.6e-03
13.0
5.9
4.3e-09
0.38
0.06
0.27
TRUE
5
The Cancer Genome Atlas
Prostate Adenocarcinoma
MRPL42
0.07
0.03
blup
49
0.03
1.4e-04
-3.2
5.4
7.2e-08
0.21
0.29
0.53
FALSE
2
GTEx
Muscle Skeletal
MRPL42
0.07
0.02
lasso
3
0.04
1.5e-04
-5.2
-5.3
1.0e-07
-0.17
0.69
0.01
FALSE