Best TWAS P=8.64e-08 · Best GWAS P=2.43e-07 conditioned to 0.258
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | TMEM121 | 0.08 | 0.10 | lasso | 3 | 0.09 | 1.8e-08 | 5.1 | -5.3 | 1.2e-07 | -0.97 | 0.01 | 0.99 | FALSE |
| 2 | METSIM | Adipose | TMEM121 | 0.04 | 0.02 | bslmm | 122 | 0.01 | 2.6e-03 | 5.1 | -5.3 | 8.6e-08 | -0.86 | 0.01 | 0.98 | TRUE |