Best TWAS P=4.93e-12 · Best GWAS P=6.33e-10 conditioned to 1.5e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | OIP5-AS1 | 0.16 | 0.21 | enet | 26 | 0.23 | 5.2e-13 | -3.1 | -5.1 | 3.1e-07 | -0.04 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Esophagus Mucosa | CHP1 | 0.19 | 0.10 | lasso | 7 | 0.09 | 1.4e-06 | -4.8 | 5.1 | 2.6e-07 | -0.07 | 0.98 | 0.02 | FALSE |
| 3 | YFS | Blood | MGA | 0.01 | 0.00 | blup | 454 | 0.00 | 7.1e-02 | -4.3 | -5.7 | 1.0e-08 | -0.25 | 0.12 | 0.10 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CHP | 0.06 | 0.01 | blup | 54 | 0.03 | 4.7e-04 | -4.2 | 6.9 | 4.9e-12 | 0.02 | 0.08 | 0.37 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LOC729082 | 0.06 | 0.01 | enet | 6 | 0.03 | 3.3e-04 | -4.5 | 5.6 | 1.8e-08 | -0.03 | 0.02 | 0.31 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CHP | 0.21 | 0.11 | lasso | 4 | 0.12 | 5.1e-13 | -5.5 | 6.1 | 1.4e-09 | 0.06 | 0.00 | 1.00 | FALSE |