Best TWAS P=9.28e-08 · Best GWAS P=6.36e-07 conditioned to 0.75
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | HSD17B1P1 | 0.06 | 0.09 | enet | 6 | 0.09 | 4.0e-08 | -4.7 | -5.3 | 9.3e-08 | 0.91 | 0.02 | 0.97 | TRUE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | NAGLU | 0.13 | 0.02 | enet | 8 | 0.04 | 1.6e-05 | 3.3 | -5.3 | 1.2e-07 | 0.78 | 0.01 | 0.81 | FALSE |