[Hub]/) : Traits : Trunk predicted mass : ← →

chr17:36,211,659-38,991,052

Best TWAS P=2.21e-14 · Best GWAS P=2.7e-14 conditioned to 2.43e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PIP4K2B 0.15 0.07 lasso 5 0.07 2.2e-06 -7.4 -6.5 7.0e-11 0.04 0.00 1.00 FALSE
2 GTEx Artery Aorta PSMB3 0.23 0.17 enet 26 0.22 2.1e-12 -7.4 -6.5 1.1e-10 0.03 0.00 1.00 FALSE
3 GTEx Artery Tibial PSMB3 0.10 0.02 enet 12 0.03 1.2e-03 -7.4 -6.7 2.6e-11 0.05 0.00 0.99 FALSE
4 GTEx Artery Tibial PIP4K2B 0.37 0.16 enet 49 0.22 2.1e-17 -7.4 -5.9 3.1e-09 0.04 0.00 1.00 FALSE
5 GTEx Esophagus Mucosa CWC25 0.11 0.07 enet 7 0.05 1.5e-04 -5.2 -5.3 9.1e-08 0.01 0.30 0.58 FALSE
6 GTEx Testis PSMB3 0.30 0.24 lasso 4 0.21 8.9e-10 -7.4 -7.6 2.2e-14 0.05 0.00 1.00 TRUE
7 METSIM Adipose MSL1 0.12 0.06 lasso 10 0.06 1.8e-09 4.9 -5.2 1.7e-07 0.30 0.99 0.00 TRUE
8 METSIM Adipose PSMB3 0.04 0.02 lasso 5 0.01 2.3e-03 -4.3 -5.3 1.1e-07 0.01 0.14 0.35 FALSE
9 NTR Blood PIP4K2B 0.02 0.01 lasso 3 0.01 6.4e-04 -7.4 7.3 2.3e-13 -0.06 0.00 0.99 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PIP4K2B 0.04 0.01 blup 56 0.03 6.3e-04 -7.5 -5.4 6.8e-08 0.09 0.00 0.95 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma PIP4K2B 0.05 0.04 blup 56 0.05 5.3e-06 -5.6 -6.0 1.7e-09 0.07 0.00 0.99 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma PSMB3 0.11 0.07 blup 42 0.07 9.4e-08 -7.4 -5.3 1.2e-07 0.05 0.00 1.00 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors PSMB3 0.12 0.09 lasso 3 0.06 3.0e-03 -7.5 -7.4 1.0e-13 0.06 0.00 0.94 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma PSMB3 0.05 0.06 lasso 1 0.05 2.4e-05 -7.4 -7.5 9.7e-14 0.05 0.00 1.00 FALSE