[Hub]/) : Traits : Trunk predicted mass :

chr17:41,946,180-43,913,030

Best TWAS P=1.38e-20 · Best GWAS P=4.69e-23 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DCAKD 0.18 0.20 lasso 6 0.20 2.6e-23 -5.17 5.2 2.1e-07 -0.44 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous NMT1 0.19 0.10 lasso 6 0.10 1.1e-08 5.46 -5.5 4.0e-08 0.32 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous DCAKD 0.21 0.09 lasso 6 0.14 6.1e-12 6.51 7.3 3.1e-13 -0.35 1.00 0.00 FALSE
4 GTEx Adipose Subcutaneous ACBD4 0.10 0.06 enet 8 0.06 1.8e-05 -7.74 -8.8 1.4e-18 0.52 0.53 0.35 TRUE
5 GTEx Adrenal Gland PLEKHM1 0.21 0.00 enet 20 0.08 1.0e-03 5.10 6.6 4.4e-11 -0.13 0.08 0.13 FALSE
6 GTEx Artery Aorta NMT1 0.14 0.08 lasso 2 0.12 3.9e-07 -5.77 -6.9 6.5e-12 0.50 0.89 0.08 FALSE
7 GTEx Artery Aorta DCAKD 0.22 0.16 enet 26 0.19 1.1e-10 -5.17 8.4 5.2e-17 -0.46 0.92 0.06 TRUE
8 GTEx Artery Aorta GJC1 0.24 0.16 lasso 6 0.14 2.2e-08 5.21 5.8 7.6e-09 -0.02 1.00 0.00 FALSE
9 GTEx Artery Coronary NMT1 0.13 0.06 enet 7 0.11 1.5e-04 6.68 -8.1 7.2e-16 0.53 0.11 0.33 FALSE
10 GTEx Artery Tibial NMT1 0.11 0.09 lasso 5 0.10 6.3e-08 -5.88 -7.3 3.9e-13 0.36 0.96 0.03 FALSE
11 GTEx Artery Tibial DCAKD 0.27 0.21 lasso 8 0.20 6.6e-16 -5.17 6.2 6.8e-10 -0.43 1.00 0.00 FALSE
12 GTEx Artery Tibial ACBD4 0.10 0.09 lasso 2 0.08 4.8e-07 -7.78 -7.8 6.3e-15 0.58 0.81 0.12 FALSE
13 GTEx Artery Tibial HEXIM1 0.13 0.08 lasso 2 0.05 1.8e-04 6.58 6.6 4.9e-11 -0.58 0.72 0.25 FALSE
14 GTEx Brain Cerebellar Hemisphere DCAKD 0.37 0.22 lasso 6 0.21 5.1e-06 -5.07 5.2 1.5e-07 -0.46 0.77 0.10 FALSE
15 GTEx Brain Cerebellar Hemisphere ACBD4 0.43 0.12 lasso 8 0.18 1.7e-05 -7.25 -6.8 9.1e-12 0.37 0.11 0.42 FALSE
16 GTEx Brain Cerebellar Hemisphere FMNL1 0.27 0.03 enet 17 0.09 2.2e-03 0.94 -5.5 3.9e-08 0.28 0.04 0.08 FALSE
17 GTEx Brain Cerebellar Hemisphere CTD-2020K17.4 0.23 0.02 enet 20 0.11 1.1e-03 -7.19 -7.1 1.2e-12 0.46 0.03 0.16 FALSE
18 GTEx Brain Cerebellum ADAM11 0.17 0.19 enet 8 0.18 4.4e-06 4.20 5.7 1.5e-08 -0.13 0.48 0.03 FALSE
19 GTEx Brain Cerebellum DCAKD 0.40 0.06 enet 20 0.24 1.4e-07 -5.11 6.8 1.4e-11 -0.39 0.80 0.06 FALSE
20 GTEx Brain Cerebellum ACBD4 0.40 0.06 lasso 8 0.17 1.0e-05 7.05 -6.8 7.8e-12 0.27 0.09 0.14 FALSE
21 GTEx Brain Frontal Cortex BA9 DCAKD 0.41 0.08 enet 23 0.10 1.2e-03 -5.07 5.5 3.7e-08 -0.41 0.24 0.06 FALSE
22 GTEx Brain Hippocampus CCDC43 0.23 0.09 enet 9 0.16 1.8e-04 -7.25 6.4 2.0e-10 -0.46 0.05 0.29 FALSE
23 GTEx Breast Mammary Tissue KANSL1 0.31 0.00 enet 9 0.11 2.6e-06 2.41 -6.0 2.5e-09 0.08 0.00 0.00 TRUE
24 GTEx Breast Mammary Tissue PLCD3 0.18 0.08 enet 18 0.14 1.5e-07 -7.19 5.3 1.4e-07 -0.29 0.56 0.02 FALSE
25 GTEx Breast Mammary Tissue DCAKD 0.16 0.13 lasso 7 0.13 2.9e-07 -6.51 6.4 1.6e-10 -0.59 0.92 0.07 FALSE
26 GTEx Breast Mammary Tissue (Male) DCAKD 0.36 0.29 lasso 8 0.33 1.4e-08 -5.11 6.9 5.8e-12 -0.58 0.42 0.43 FALSE
27 GTEx Breast Mammary Tissue (Female) PLCD3 0.15 0.14 enet 12 0.12 2.1e-04 -7.25 5.5 4.2e-08 -0.32 0.10 0.05 FALSE
28 GTEx Breast Mammary Tissue (Female) FZD2 0.10 0.08 lasso 2 0.05 1.1e-02 5.77 5.9 3.3e-09 -0.07 0.05 0.07 FALSE
29 GTEx Cells EBV-transformed lymphocytes GJC1 0.34 0.33 lasso 4 0.33 2.3e-11 5.21 5.4 7.2e-08 0.01 1.00 0.00 FALSE
30 GTEx Cells Transformed fibroblasts PLCD3 0.23 0.04 lasso 5 0.08 1.3e-06 2.36 6.2 4.1e-10 -0.48 0.95 0.01 FALSE
31 GTEx Cells Transformed fibroblasts GJC1 0.41 0.40 enet 32 0.44 8.7e-36 5.16 5.4 8.0e-08 -0.02 1.00 0.00 FALSE
32 GTEx Cells Transformed fibroblasts HEXIM1 0.11 0.10 lasso 2 0.08 1.6e-06 6.58 6.6 4.0e-11 -0.58 0.65 0.30 FALSE
33 GTEx Colon Sigmoid DCAKD 0.18 0.16 lasso 3 0.16 2.1e-06 -5.17 5.6 2.6e-08 -0.44 0.63 0.12 FALSE
34 GTEx Colon Transverse DCAKD 0.28 0.18 lasso 8 0.26 1.5e-12 -5.11 6.8 1.1e-11 -0.41 0.99 0.00 FALSE
35 GTEx Esophagus Gastroesophageal Junction NMT1 0.24 0.21 lasso 4 0.22 2.8e-08 5.46 -8.1 5.9e-16 0.54 0.35 0.63 TRUE
36 GTEx Esophagus Gastroesophageal Junction DCAKD 0.42 0.36 lasso 7 0.37 3.8e-14 -6.51 6.7 1.6e-11 -0.58 0.97 0.03 FALSE
37 GTEx Esophagus Mucosa ADAM11 0.19 0.14 lasso 4 0.12 1.2e-08 5.73 5.8 7.3e-09 -0.07 0.99 0.00 FALSE
38 GTEx Esophagus Mucosa DCAKD 0.33 0.32 enet 20 0.35 5.6e-24 -5.17 6.5 8.4e-11 -0.51 1.00 0.00 TRUE
39 GTEx Esophagus Mucosa ACBD4 0.14 0.10 lasso 4 0.10 4.5e-07 6.99 -7.4 1.3e-13 0.13 0.59 0.08 FALSE
40 GTEx Esophagus Muscularis NMT1 0.13 0.12 lasso 2 0.14 1.5e-08 5.46 -6.0 1.8e-09 0.36 0.97 0.02 FALSE
41 GTEx Esophagus Muscularis DCAKD 0.27 0.29 lasso 5 0.30 2.1e-18 -5.17 6.0 1.9e-09 -0.47 1.00 0.00 FALSE
42 GTEx Heart Left Ventricle DCAKD 0.17 0.17 lasso 3 0.17 2.3e-09 -5.17 6.6 3.6e-11 -0.55 0.98 0.01 FALSE
43 GTEx Lung HIGD1B 0.09 0.04 lasso 3 0.04 2.2e-04 5.81 -5.6 1.9e-08 -0.01 0.78 0.01 FALSE
44 GTEx Lung DCAKD 0.22 0.05 enet 27 0.10 5.2e-08 5.45 6.3 2.8e-10 -0.44 0.96 0.02 FALSE
45 GTEx Muscle Skeletal PLCD3 0.18 0.10 enet 8 0.10 1.7e-10 6.99 7.3 2.1e-13 -0.12 1.00 0.00 FALSE
46 GTEx Muscle Skeletal DCAKD 0.12 0.06 enet 16 0.07 9.9e-08 -6.51 7.4 1.3e-13 -0.54 0.89 0.11 FALSE
47 GTEx Nerve Tibial NMT1 0.16 0.14 lasso 6 0.11 2.0e-08 5.46 -5.4 8.3e-08 0.33 1.00 0.00 FALSE
48 GTEx Nerve Tibial DCAKD 0.35 0.29 enet 21 0.30 1.6e-21 5.51 6.6 3.6e-11 -0.42 1.00 0.00 FALSE
49 GTEx Nerve Tibial ACBD4 0.21 0.10 lasso 5 0.11 4.2e-08 -7.25 -8.8 1.4e-18 0.47 0.93 0.07 FALSE
50 GTEx Pancreas NMT1 0.19 0.12 enet 18 0.07 8.0e-04 -5.77 -6.0 2.6e-09 0.27 0.32 0.13 FALSE
51 GTEx Prostate NMT1 0.43 0.28 lasso 6 0.25 5.3e-07 5.64 -6.1 1.4e-09 0.36 0.58 0.12 FALSE
52 GTEx Skin Not Sun Exposed Suprapubic DCAKD 0.30 0.21 lasso 6 0.20 5.0e-11 -6.51 7.1 1.0e-12 -0.58 1.00 0.00 FALSE
53 GTEx Skin Sun Exposed Lower leg DCAKD 0.33 0.20 enet 30 0.31 2.4e-26 -5.17 6.6 3.3e-11 -0.27 1.00 0.00 FALSE
54 GTEx Skin Sun Exposed Lower leg ACBD4 0.06 0.05 lasso 4 0.02 3.8e-03 7.05 -8.8 1.1e-18 0.33 0.19 0.08 FALSE
55 GTEx Stomach DCAKD 0.29 0.17 enet 25 0.20 9.4e-10 -5.17 7.4 1.0e-13 -0.48 0.58 0.41 FALSE
56 GTEx Thyroid NMT1 0.09 0.09 lasso 2 0.08 8.1e-07 5.46 -5.6 2.5e-08 0.32 0.95 0.02 FALSE
57 GTEx Thyroid PLCD3 0.12 0.01 enet 20 0.07 8.2e-06 6.99 6.3 2.8e-10 -0.04 0.77 0.01 FALSE
58 GTEx Thyroid DCAKD 0.25 0.26 enet 17 0.27 9.4e-21 -6.51 6.3 2.3e-10 -0.57 1.00 0.00 FALSE
59 GTEx Thyroid ACBD4 0.20 0.16 enet 23 0.15 1.2e-11 -7.74 -9.3 1.4e-20 0.51 1.00 0.00 TRUE
60 GTEx Whole Blood DCAKD 0.07 0.08 lasso 2 0.06 1.8e-06 -5.17 5.8 9.1e-09 -0.52 0.95 0.03 FALSE
61 METSIM Adipose C17orf104 0.05 0.02 bslmm 404 0.04 4.2e-06 4.71 -5.9 3.7e-09 0.11 0.91 0.00 FALSE
62 METSIM Adipose NMT1 0.13 0.11 lasso 6 0.11 5.7e-16 -5.40 -5.7 1.6e-08 0.47 1.00 0.00 FALSE
63 YFS Blood DCAKD 0.26 0.24 enet 47 0.27 1.3e-88 -5.17 5.7 1.4e-08 -0.43 1.00 0.00 FALSE
64 YFS Blood FZD2 0.15 0.12 bslmm 362 0.13 1.8e-39 5.75 5.4 7.7e-08 -0.08 0.83 0.17 FALSE
65 YFS Blood HEXIM2 0.02 0.01 bslmm 279 0.01 1.0e-05 6.68 -7.0 1.8e-12 0.61 0.49 0.47 FALSE
66 YFS Blood NMT1 0.02 0.01 lasso 6 0.01 5.0e-03 6.97 -8.0 1.7e-15 0.37 0.28 0.05 FALSE
67 The Cancer Genome Atlas Bladder Urothelial Carcinoma LOC644172 0.08 0.00 blup 79 0.04 3.2e-04 3.33 6.0 1.5e-09 -0.51 0.07 0.27 FALSE
68 The Cancer Genome Atlas Breast Invasive Carcinoma DCAKD 0.04 0.02 lasso 4 0.02 6.3e-06 -6.51 5.6 1.9e-08 -0.55 0.22 0.77 FALSE
69 The Cancer Genome Atlas Breast Invasive Carcinoma LOC644172 0.14 0.07 enet 10 0.12 1.2e-23 1.41 5.6 1.8e-08 -0.35 1.00 0.00 FALSE
70 The Cancer Genome Atlas Breast Invasive Carcinoma MGC57346 0.02 0.00 blup 62 0.02 2.2e-05 1.57 5.6 1.7e-08 -0.53 0.04 0.58 FALSE
71 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma LOC644172 0.19 -0.01 blup 81 0.03 1.3e-02 1.57 6.3 2.2e-10 -0.47 0.02 0.56 FALSE
72 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DCAKD 0.07 0.07 lasso 4 0.07 1.4e-08 -6.51 7.9 3.8e-15 -0.56 0.09 0.91 FALSE
73 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DCAKD 0.03 0.04 lasso 2 0.03 3.8e-04 -5.51 5.7 1.2e-08 -0.43 0.27 0.32 FALSE
74 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NMT1 0.05 0.04 lasso 2 0.04 1.5e-05 -5.88 -5.9 2.9e-09 0.39 0.81 0.02 FALSE
75 The Cancer Genome Atlas Brain Lower Grade Glioma ACBD4 0.08 0.04 enet 9 0.04 6.9e-06 -7.74 -7.5 5.3e-14 0.50 0.95 0.01 FALSE
76 The Cancer Genome Atlas Brain Lower Grade Glioma LOC644172 0.04 0.00 enet 15 0.02 4.0e-03 -9.89 6.7 2.7e-11 -0.60 0.00 0.75 FALSE
77 The Cancer Genome Atlas Brain Lower Grade Glioma NMT1 0.08 0.04 blup 83 0.05 3.5e-06 -5.17 -6.3 3.1e-10 0.37 0.96 0.02 FALSE
78 The Cancer Genome Atlas Lung Adenocarcinoma DCAKD 0.03 0.03 lasso 3 0.04 3.2e-05 5.16 5.5 4.4e-08 -0.39 0.46 0.12 FALSE
79 The Cancer Genome Atlas Lung Adenocarcinoma NMT1 0.04 0.00 blup 81 0.01 1.9e-02 -5.77 -7.6 3.4e-14 0.27 0.03 0.70 FALSE
80 The Cancer Genome Atlas Lung Adenocarcinoma PLCD3 0.04 0.01 blup 64 0.01 2.3e-02 6.99 -6.9 4.7e-12 0.27 0.05 0.08 FALSE
81 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DCAKD 0.04 0.02 blup 66 0.02 3.5e-03 -5.54 5.7 9.3e-09 -0.48 0.25 0.36 FALSE
82 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma HEXIM1 0.06 0.01 blup 47 0.03 3.3e-03 3.06 6.2 6.3e-10 -0.24 0.01 0.13 FALSE
83 The Cancer Genome Atlas Pancreatic Adenocarcinoma NMT1 0.23 0.08 blup 82 0.12 1.1e-05 5.51 -8.1 6.7e-16 0.55 0.05 0.90 FALSE
84 The Cancer Genome Atlas Prostate Adenocarcinoma ACBD4 0.04 0.01 enet 7 0.03 2.2e-04 5.10 -7.5 6.2e-14 0.44 0.09 0.16 FALSE
85 The Cancer Genome Atlas Prostate Adenocarcinoma LOC644172 0.15 0.01 blup 77 0.06 1.0e-06 6.97 6.6 3.4e-11 -0.40 0.19 0.28 FALSE
86 The Cancer Genome Atlas Prostate Adenocarcinoma NMT1 0.09 0.08 lasso 3 0.09 1.1e-09 5.51 -6.3 3.0e-10 0.46 0.91 0.09 FALSE
87 The Cancer Genome Atlas Stomach Adenocarcinoma LOC644172 0.17 0.00 enet 16 0.06 1.9e-05 1.41 5.5 5.1e-08 -0.32 0.17 0.07 FALSE
88 The Cancer Genome Atlas Testicular Germ Cell Tumors LOC644172 0.20 0.01 enet 12 0.06 4.5e-03 -3.83 5.9 3.7e-09 -0.47 0.06 0.08 FALSE
89 The Cancer Genome Atlas Thyroid Carcinoma DCAKD 0.12 0.13 lasso 8 0.13 5.5e-13 -5.17 5.5 4.9e-08 -0.47 0.97 0.03 FALSE
90 The Cancer Genome Atlas Thyroid Carcinoma GFAP 0.09 0.05 lasso 2 0.04 3.4e-05 5.15 -5.3 1.4e-07 -0.01 0.31 0.37 FALSE
91 The Cancer Genome Atlas Thyroid Carcinoma HEXIM1 0.05 0.05 blup 47 0.04 8.5e-05 -9.89 9.2 2.3e-20 -0.84 0.00 1.00 FALSE
92 The Cancer Genome Atlas Thyroid Carcinoma NMT1 0.18 0.19 enet 20 0.20 3.8e-19 -5.77 -6.5 7.7e-11 0.40 1.00 0.00 FALSE
93 The Cancer Genome Atlas Thyroid Carcinoma PLCD3 0.24 0.16 lasso 5 0.20 2.8e-19 6.99 7.6 2.2e-14 -0.15 1.00 0.00 FALSE