[Hub]/) : Traits : Trunk predicted mass :

chr3:55,894,951-57,412,804

Best TWAS P=2.4e-18 · Best GWAS P=4.69e-15 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous FAM208A 0.12 0.09 enet 11 0.12 1.1e-09 -4.1 6.5 9.1e-11 -0.82 0.03 0.97 FALSE
2 GTEx Brain Hippocampus CCDC66 0.23 0.23 lasso 3 0.20 2.1e-05 -5.9 5.6 2.2e-08 -0.64 0.25 0.17 TRUE
3 GTEx Cells EBV-transformed lymphocytes CCDC66 0.45 0.27 enet 37 0.29 3.7e-10 -6.5 -5.5 3.9e-08 0.45 0.98 0.01 TRUE
4 GTEx Cells Transformed fibroblasts FAM208A 0.10 0.00 lasso 4 0.00 1.3e-01 -7.8 7.2 5.0e-13 -0.82 0.01 0.97 FALSE
5 GTEx Pituitary CCDC66 0.16 0.16 enet 31 0.12 6.8e-04 -3.4 6.3 3.3e-10 -0.68 0.02 0.92 FALSE
6 GTEx Skin Sun Exposed Lower leg FAM208A 0.06 0.04 lasso 2 0.03 2.0e-03 -5.8 5.7 9.4e-09 -0.65 0.20 0.49 TRUE
7 YFS Blood CCDC66 0.11 0.09 lasso 8 0.11 6.0e-34 -6.5 -6.6 4.4e-11 0.53 0.99 0.01 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC66 0.09 0.03 lasso 8 0.05 4.2e-11 -5.6 -7.6 2.1e-14 0.54 0.20 0.80 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma CCDC66 0.14 0.12 lasso 2 0.10 1.2e-06 -5.6 -5.6 2.5e-08 0.47 0.62 0.17 FALSE
10 The Cancer Genome Atlas Glioblastoma Multiforme CCDC66 0.19 0.02 enet 14 0.12 1.7e-04 2.3 -5.6 2.1e-08 0.16 0.04 0.07 TRUE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC66 0.05 0.05 blup 56 0.06 1.0e-07 -7.8 -8.7 5.0e-18 0.79 0.00 1.00 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C3orf63 0.03 0.01 enet 4 0.01 1.3e-02 -7.8 7.1 1.5e-12 -0.89 0.01 0.89 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CCDC66 0.09 0.05 blup 56 0.06 5.3e-07 -6.5 -6.7 2.3e-11 0.69 0.82 0.18 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma CCDC66 0.16 0.13 enet 12 0.16 3.1e-17 -6.5 -6.3 3.4e-10 0.34 0.98 0.02 FALSE
15 The Cancer Genome Atlas Lung Adenocarcinoma CCDC66 0.05 0.06 blup 56 0.05 9.7e-07 -7.8 -8.7 2.4e-18 0.73 0.00 1.00 TRUE
16 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CCDC66 0.03 0.03 blup 56 0.03 9.6e-05 -5.6 -7.1 9.1e-13 0.51 0.34 0.26 FALSE
17 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CCDC66 0.08 0.01 blup 56 0.07 7.2e-04 -6.5 -6.3 2.6e-10 0.32 0.12 0.07 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma CCDC66 0.15 0.10 enet 11 0.13 7.3e-14 -5.6 -6.4 1.8e-10 0.48 0.98 0.01 TRUE
19 The Cancer Genome Atlas Rectum Adenocarcinoma CCDC66 0.20 -0.01 lasso 3 0.00 3.0e-01 -5.6 -5.1 2.8e-07 0.52 0.02 0.21 FALSE
20 The Cancer Genome Atlas Stomach Adenocarcinoma CCDC66 0.05 0.01 blup 57 0.02 8.4e-03 -5.6 -7.2 7.9e-13 0.55 0.07 0.57 FALSE