Best TWAS P=4.91e-08 · Best GWAS P=1.92e-08 conditioned to 8.5e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CEP63 | 0.09 | 0.06 | bslmm | 502 | 0.07 | 1.4e-08 | -3.5 | 5.2 | 2.2e-07 | 0.34 | 0.93 | 0.03 | FALSE |
2 | CommonMind | Brain Pre-frontal Cortex | KY | 0.10 | 0.09 | bslmm | 499 | 0.10 | 7.5e-12 | -2.9 | -5.5 | 4.9e-08 | -0.36 | 0.96 | 0.00 | TRUE |
3 | The Cancer Genome Atlas | Glioblastoma Multiforme | ANAPC13 | 0.24 | 0.09 | lasso | 12 | 0.08 | 1.8e-03 | -3.7 | 5.3 | 1.2e-07 | 0.70 | 0.04 | 0.39 | FALSE |