Best TWAS P=9.51e-11 · Best GWAS P=1.79e-09 conditioned to 0.366
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | RP11-738E22.3 | 0.07 | 0.04 | lasso | 6 | 0.05 | 7.7e-08 | -6.0 | 6.4 | 1.6e-10 | -0.98 | 0.00 | 1.00 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | REST | 0.04 | 0.02 | bslmm | 536 | 0.02 | 3.4e-03 | -5.5 | -5.5 | 5.1e-08 | 0.58 | 0.06 | 0.86 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | REST | 0.04 | 0.01 | lasso | 5 | 0.02 | 7.8e-04 | -6.0 | -6.5 | 9.5e-11 | 0.86 | 0.01 | 0.96 | TRUE |