Best TWAS P=1.7e-08 · Best GWAS P=1.18e-15 conditioned to 7.08e-14
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | TSLP | 0.16 | 0.18 | lasso | 7 | 0.18 | 8.5e-26 | -5.6 | 5.6 | 2.1e-08 | -0.09 | 1.00 | 0.00 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TSLP | 0.05 | 0.02 | blup | 39 | 0.02 | 7.9e-04 | -5.4 | 5.6 | 1.7e-08 | -0.10 | 0.24 | 0.06 | TRUE |
3 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | TSLP | 0.12 | 0.11 | lasso | 3 | 0.08 | 6.9e-04 | -5.6 | 5.4 | 5.3e-08 | -0.09 | 0.11 | 0.06 | FALSE |