373 significantly associated models · 70 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 102118712 | 103686111 | 5 | 1 | 4.3e-31 | 1.3e-24 | 3.6e-02 | 96 | IL1RL1 |
2 | 2 | 160551143 | 161166234 | 1 | 1 | 1.4e-07 | 3.1e-05 | 2.4e-02 | 71 | PLA2R1 |
3 | 2 | 241941773 | 243048760 | 6 | 2 | 1.4e-12 | 5.5e-14 | 6.9e-01 | 100 | AC114730.7 D2HGDH |
4 | 3 | 48606701 | 50921261 | 15 | 1 | 2.0e-13 | 7.2e-13 | 1.0e+00 | 100 | RBM6 |
5 | 4 | 122842267 | 123530993 | 1 | 1 | 5.5e-08 | 4.1e-07 | 1.4e-02 | 76 | KIAA1109 |
6 | 5 | 109716442 | 111105293 | 1 | 1 | 1.7e-08 | 1.2e-15 | 7.1e-14 | 13 | TSLP |
7 | 9 | 4934896 | 7345304 | 2 | 2 | 2.6e-11 | 3.8e-29 | 1.2e-14 | 52 | GLDC KIAA1432 |
8 | 9 | 138920796 | 140321666 | 1 | 1 | 7.9e-10 | 2.4e-09 | 1.0e+00 | 100 | SNHG7 |
9 | 11 | 75678647 | 77069746 | 1 | 1 | 9.6e-08 | 2.0e-12 | 2.0e-06 | 54 | LRRC32 |
10 | 11 | 110776537 | 112491227 | 5 | 1 | 9.6e-09 | 1.0e-08 | 1.0e+00 | 100 | FDXACB1 |
11 | 12 | 66068136 | 67896003 | 1 | 1 | 2.0e-07 | 8.4e-06 | 7.9e-04 | 43 | GRIP1 |
12 | 13 | 99155113 | 100728229 | 1 | 1 | 1.7e-08 | 2.5e-07 | 8.7e-02 | 89 | UBAC2 |
13 | 15 | 66662107 | 68183665 | 1 | 1 | 1.4e-13 | 8.8e-15 | 8.6e-03 | 88 | SMAD3 |
14 | 16 | 10329905 | 12010444 | 5 | 1 | 3.3e-13 | 1.8e-18 | 8.8e-07 | 69 | DEXI |
15 | 16 | 29972690 | 31370090 | 1 | 1 | 8.9e-08 | 2.8e-06 | 7.7e-01 | 100 | FBRS |
16 | 17 | 36710513 | 39048774 | 16 | 1 | 1.9e-14 | 2.6e-13 | 5.7e-02 | 93 | RAPGEFL1 |
17 | 20 | 61576647 | 62912463 | 7 | 1 | 6.3e-10 | 7.3e-10 | 1.0e+00 | 100 | ARFRP1 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Brain Frontal Cortex BA9 | 4 | 0.433 | 2.0 |
GTEx | Adipose Visceral Omentum | 4 | 0.196 | 1.9 |
GTEx | Artery Aorta | 4 | 0.134 | 1.9 |
GTEx | Artery Tibial | 8 | 0.213 | 1.9 |
GTEx | Brain Cerebellar Hemisphere | 5 | 0.336 | 1.9 |
GTEx | Brain Cerebellum | 6 | 0.303 | 1.9 |
GTEx | Brain Cortex | 3 | 0.290 | 1.9 |
GTEx | Brain Putamen basal ganglia | 3 | 0.481 | 1.9 |
GTEx | Breast Mammary Tissue | 8 | 0.405 | 1.9 |
GTEx | Breast Mammary Tissue (Female) | 4 | 0.243 | 1.9 |
GTEx | Cells Transformed fibroblasts | 12 | 0.286 | 1.9 |
GTEx | Colon Sigmoid | 2 | 0.137 | 1.9 |
GTEx | Colon Transverse | 8 | 0.388 | 1.9 |
GTEx | Esophagus Muscularis | 6 | 0.186 | 1.9 |
GTEx | Prostate | 2 | 0.240 | 1.9 |
GTEx | Skin Not Sun Exposed Suprapubic | 7 | 0.285 | 1.9 |
GTEx | Skin Sun Exposed Lower leg | 9 | 0.247 | 1.9 |
GTEx | Small Intestine Terminal Ileum | 1 | 0.217 | 1.9 |
GTEx | Spleen | 8 | 0.567 | 1.9 |
GTEx | Thyroid | 13 | 0.325 | 1.9 |
GTEx | Uterus | 2 | 0.353 | 1.9 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 6 | 0.356 | 1.9 |
GTEx | Adipose Subcutaneous | 5 | 0.143 | 1.8 |
GTEx | Artery Coronary | 1 | 0.085 | 1.8 |
GTEx | Brain Hypothalamus | 1 | 0.169 | 1.8 |
GTEx | Brain Nucleus accumbens basal ganglia | 3 | 0.347 | 1.8 |
GTEx | Breast Mammary Tissue (Male) | 3 | 0.251 | 1.8 |
GTEx | Cells EBV-transformed lymphocytes | 2 | 0.141 | 1.8 |
GTEx | Esophagus Gastroesophageal Junction | 3 | 0.208 | 1.8 |
GTEx | Esophagus Mucosa | 9 | 0.271 | 1.8 |
GTEx | Heart Atrial Appendage | 4 | 0.253 | 1.8 |
GTEx | Heart Left Ventricle | 2 | 0.131 | 1.8 |
GTEx | Lung | 5 | 0.174 | 1.8 |
GTEx | Nerve Tibial | 5 | 0.116 | 1.8 |
GTEx | Ovary | 1 | 0.110 | 1.8 |
GTEx | Pancreas | 4 | 0.245 | 1.8 |
GTEx | Pituitary | 3 | 0.269 | 1.8 |
GTEx | Stomach | 3 | 0.206 | 1.8 |
GTEx | Testis | 9 | 0.285 | 1.8 |
GTEx | Whole Blood | 7 | 0.351 | 1.8 |
NTR | Blood | 5 | 0.208 | 1.8 |
ROSMAP | Brain Pre-frontal Cortex | 8 | 0.182 | 1.8 |
YFS | Blood | 7 | 0.152 | 1.8 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 4 | 0.242 | 1.8 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 6 | 0.220 | 1.8 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 13 | 0.317 | 1.8 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 4 | 0.195 | 1.8 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 8 | 0.272 | 1.8 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 7 | 0.279 | 1.8 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 7 | 0.421 | 1.8 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.187 | 1.8 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 4 | 0.313 | 1.8 |
The Cancer Genome Atlas | Thyroid Carcinoma | 11 | 0.213 | 1.8 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 1 | 0.197 | 1.8 |
GTEx | Adrenal Gland | 3 | 0.206 | 1.7 |
GTEx | Brain Caudate basal ganglia | 2 | 0.217 | 1.7 |
GTEx | Muscle Skeletal | 7 | 0.242 | 1.7 |
GTEx | Vagina | 1 | 0.157 | 1.7 |
METSIM | Adipose | 7 | 0.152 | 1.7 |
CommonMind | Brain Pre-frontal Cortex | 12 | 0.223 | 1.7 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 12 | 0.272 | 1.7 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 3 | 0.273 | 1.7 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 6 | 0.291 | 1.7 |
The Cancer Genome Atlas | Esophageal Carcinoma | 1 | 0.146 | 1.7 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 2 | 0.196 | 1.7 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 10 | 0.232 | 1.7 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 3 | 0.271 | 1.7 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 3 | 0.188 | 1.7 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 12 | 0.260 | 1.7 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.6 |
GTEx | Liver | 2 | 0.279 | 1.6 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 3 | 0.226 | 1.6 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 2 | 0.289 | 1.6 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 1 | 0.094 | 1.6 |