Best TWAS P=3.74e-08 · Best GWAS P=1.64e-07 conditioned to 0.226
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | NRBF2 | 0.30 | 0.26 | enet | 24 | 0.21 | 1.4e-06 | -5.0 | -5.3 | 9.4e-08 | 0.72 | 0.05 | 0.94 | FALSE |
| 2 | GTEx | Stomach | NRBF2 | 0.09 | 0.04 | lasso | 6 | 0.03 | 1.6e-02 | -3.9 | -5.4 | 6.8e-08 | 0.87 | 0.04 | 0.65 | FALSE |
| 3 | GTEx | Testis | NRBF2 | 0.14 | 0.08 | lasso | 12 | 0.09 | 6.7e-05 | 4.9 | -5.3 | 1.1e-07 | 0.72 | 0.05 | 0.93 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | NRBF2 | 0.04 | 0.04 | enet | 5 | 0.03 | 1.3e-04 | 4.6 | -5.1 | 3.1e-07 | 0.72 | 0.02 | 0.91 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NRBF2 | 0.10 | 0.06 | lasso | 7 | 0.08 | 3.5e-09 | -5.2 | -5.5 | 3.7e-08 | 0.83 | 0.00 | 1.00 | TRUE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | REEP3 | 0.04 | 0.04 | blup | 59 | 0.05 | 1.8e-06 | -5.2 | 5.2 | 1.7e-07 | -0.83 | 0.01 | 0.99 | FALSE |