Best TWAS P=3.55e-08 · Best GWAS P=1.88e-07 conditioned to 0.72
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | COMMD7 | 0.05 | 0.03 | lasso | 3 | 0.03 | 4.9e-05 | -5.2 | -5.5 | 3.6e-08 | 0.92 | 0.00 | 0.99 | TRUE |
| 2 | GTEx | Colon Transverse | DNMT3B | 0.21 | 0.06 | lasso | 7 | 0.07 | 3.0e-04 | -4.1 | -5.3 | 1.3e-07 | 0.85 | 0.02 | 0.96 | FALSE |
| 3 | GTEx | Colon Transverse | COMMD7 | 0.16 | 0.01 | lasso | 5 | 0.00 | 2.5e-01 | -4.1 | -5.2 | 2.6e-07 | 0.75 | 0.05 | 0.82 | FALSE |