Best TWAS P=1.99e-12 · Best GWAS P=6.23e-11 conditioned to 0.256
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CPEB2 | 0.12 | 0.12 | lasso | 3 | 0.10 | 3.9e-07 | -6.2 | 6.2 | 6.4e-10 | -0.74 | 0.08 | 0.92 | FALSE |
| 2 | GTEx | Nerve Tibial | CPEB2 | 0.12 | 0.03 | lasso | 5 | 0.03 | 4.6e-03 | -5.2 | 6.5 | 6.0e-11 | -0.80 | 0.04 | 0.92 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RP11-665G4.1 | 0.09 | 0.11 | lasso | 1 | 0.09 | 5.0e-08 | -5.9 | 5.9 | 3.1e-09 | -0.69 | 0.17 | 0.83 | FALSE |
| 4 | NTR | Blood | CPEB2 | 0.03 | 0.03 | enet | 23 | 0.02 | 1.4e-08 | -6.5 | 6.1 | 1.2e-09 | -0.89 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | CPEB2 | 0.03 | 0.02 | enet | 6 | 0.01 | 7.2e-03 | -6.2 | -7.0 | 2.0e-12 | 0.84 | 0.01 | 0.81 | TRUE |