Best TWAS P=8.31e-10 · Best GWAS P=1.46e-12 conditioned to 0.000369
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CENPW | 0.04 | 0.06 | lasso | 10 | 0.06 | 2.4e-07 | -5.8 | 6.1 | 1.2e-09 | -0.93 | 0.21 | 0.79 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CENPW | 0.04 | 0.05 | lasso | 5 | 0.05 | 2.6e-06 | -5.8 | 6.0 | 2.0e-09 | -0.90 | 0.02 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CENPW | 0.04 | 0.06 | blup | 35 | 0.05 | 9.2e-07 | -5.7 | 6.1 | 8.3e-10 | -0.90 | 0.02 | 0.98 | TRUE |