Best TWAS P=8.23e-14 · Best GWAS P=1.29e-13 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | C4orf22 | 0.09 | 0.08 | lasso | 5 | 0.07 | 4.5e-09 | 7.2 | 7.5 | 8.2e-14 | 0.96 | 0.01 | 0.99 | TRUE |
2 | CommonMind | Brain Pre-frontal Cortex | FGF5 | 0.07 | 0.06 | lasso | 2 | 0.05 | 5.4e-07 | 7.2 | 6.8 | 9.7e-12 | 0.91 | 0.01 | 0.99 | TRUE |
3 | GTEx | Breast Mammary Tissue | PRDM8 | 0.23 | 0.06 | lasso | 6 | 0.05 | 9.5e-04 | 6.0 | 5.9 | 3.8e-09 | 0.28 | 0.43 | 0.05 | TRUE |