Best TWAS P=3.28e-08 · Best GWAS P=2.85e-11 conditioned to 0.013
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PLEKHH2 | 0.50 | 0.18 | lasso | 9 | 0.31 | 9.4e-18 | -1.8 | 5.4 | 8.3e-08 | 0.51 | 0.75 | 0.24 | TRUE |
| 2 | GTEx | Artery Tibial | PLEKHH2 | 0.49 | 0.17 | enet | 48 | 0.29 | 2.6e-23 | -1.8 | 5.4 | 6.7e-08 | 0.57 | 1.00 | 0.00 | FALSE |
| 3 | GTEx | Nerve Tibial | ZFP36L2 | 0.06 | 0.00 | lasso | 8 | 0.01 | 3.5e-02 | 5.5 | -5.5 | 3.3e-08 | -0.81 | 0.05 | 0.82 | TRUE |