Best TWAS P=6.2e-11 · Best GWAS P=4.2e-22 conditioned to 1.07e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | SPAST | 0.18 | 0.04 | lasso | 3 | 0.08 | 0.0013 | -7.3 | 6.5 | 6.2e-11 | -0.66 | 0.05 | 0.17 | TRUE |
| 2 | GTEx | Nerve Tibial | RP11-563N4.1 | 0.11 | 0.02 | enet | 10 | 0.02 | 0.0259 | -2.1 | -5.9 | 3.0e-09 | 0.15 | 0.34 | 0.04 | FALSE |