Best TWAS P=2.16e-08 · Best GWAS P=1.39e-08 conditioned to 0.0429
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 5.4 | -5.6 | 2.2e-08 | -0.79 | 0.03 | 0.55 | TRUE |
2 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 5.5 | -5.6 | 2.2e-08 | -0.87 | 0.02 | 0.98 | FALSE |