Best TWAS P=3.61e-14 · Best GWAS P=7.84e-22 conditioned to 4.16e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SUPT3H | 0.33 | 0.26 | enet | 43 | 0.44 | 2.5e-59 | 4.3 | 7.6 | 3.6e-14 | -0.45 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Brain Cerebellum | SUPT3H | 0.38 | 0.09 | enet | 46 | 0.22 | 2.8e-07 | 4.1 | 6.5 | 1.1e-10 | -0.41 | 0.44 | 0.27 | FALSE |
| 3 | GTEx | Brain Frontal Cortex BA9 | SUPT3H | 0.37 | 0.14 | lasso | 11 | 0.18 | 1.3e-05 | 4.1 | 7.3 | 3.9e-13 | -0.49 | 0.51 | 0.12 | FALSE |
| 4 | GTEx | Brain Nucleus accumbens basal ganglia | SUPT3H | 0.16 | 0.11 | lasso | 4 | 0.08 | 3.6e-03 | 5.3 | 5.3 | 1.1e-07 | -0.25 | 0.22 | 0.08 | FALSE |
| 5 | GTEx | Testis | SUPT3H | 0.30 | 0.16 | lasso | 7 | 0.17 | 6.7e-08 | 5.3 | 5.2 | 1.6e-07 | -0.28 | 0.99 | 0.00 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SUPT3H | 0.04 | 0.01 | blup | 191 | 0.02 | 6.5e-03 | 4.3 | 5.9 | 4.7e-09 | -0.21 | 0.68 | 0.01 | FALSE |