Best TWAS P=9.56e-12 · Best GWAS P=2.92e-26 conditioned to 7.19e-19
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | ATG5 | 0.09 | 0.00 | bslmm | 662 | 0.03 | 0.00023 | -2.9 | -6.3 | 3.4e-10 | -0.02 | 0.63 | 0.01 | TRUE |
2 | GTEx | Brain Cerebellar Hemisphere | PREP | 0.44 | 0.01 | enet | 36 | 0.10 | 0.00165 | 5.5 | 6.8 | 9.6e-12 | -0.37 | 0.06 | 0.06 | TRUE |