Best TWAS P=6.42e-75 · Best GWAS P=1.75e-113 conditioned to 3.98e-48
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | TWIST1 | 0.15 | 0.11 | lasso | 6 | 0.17 | 5.7e-12 | 21 | 18.3 | 6.4e-75 | 0.73 | 0.02 | 0.98 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | TWIST1 | 0.09 | 0.02 | blup | 618 | 0.02 | 8.5e-04 | 20 | 8.4 | 3.3e-17 | 0.60 | 0.02 | 0.95 | TRUE |