Best TWAS P=1.04e-11 · Best GWAS P=1.46e-14 conditioned to 2.21e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | MVB12B | 0.28 | 0.10 | enet | 13 | 0.09 | 9.3e-06 | -7.1 | 6.8 | 1.0e-11 | -0.67 | 0.19 | 0.77 | TRUE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | FAM125B | 0.07 | 0.01 | blup | 160 | 0.04 | 2.7e-05 | -2.9 | 5.2 | 2.1e-07 | -0.59 | 0.17 | 0.44 | FALSE |