TWAS hub - MVB12B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1300	0.0440	1.5e-03	-0.003	NA	0.029	NA	0.004	9.6e-01	NA	1.9e-03	NA	1.3e-01
2	GTEx	Artery Aorta	0.2830	0.0660	1.4e-05	0.095	NA	0.092	NA	0.091	6.3e-06	NA	9.3e-06	NA	1.1e-05
3	GTEx	Artery Tibial	0.0967	0.0341	1.6e-03	0.048	NA	0.037	NA	0.044	1.2e-04	NA	7.0e-04	NA	2.0e-04
4	GTEx	Cells Transformed fibroblasts	0.1930	0.0430	1.3e-08	0.184	NA	0.158	NA	0.172	8.9e-14	NA	6.6e-12	NA	6.4e-13
5	GTEx	Esophagus Mucosa	0.1170	0.0480	8.6e-03	0.008	NA	0.001	NA	0.011	9.2e-02	NA	2.5e-01	NA	5.5e-02
6	GTEx	Esophagus Muscularis	0.2410	0.0650	1.5e-04	0.058	NA	0.078	NA	0.062	2.1e-04	NA	1.9e-05	NA	1.2e-04
7	GTEx	Pancreas	0.1760	0.0680	4.6e-03	0.059	NA	0.051	NA	0.040	1.7e-03	NA	3.3e-03	NA	8.5e-03
8	GTEx	Skin Not Sun Exposed Suprapubic	0.1250	0.0480	2.9e-03	0.000	NA	-0.002	NA	-0.002	3.3e-01	NA	4.1e-01	NA	4.4e-01
9	GTEx	Skin Sun Exposed Lower leg	0.1830	0.0390	1.3e-09	0.104	NA	0.155	NA	0.125	6.2e-09	NA	7.8e-13	NA	1.6e-10
10	GTEx	Whole Blood	0.0930	0.0340	2.8e-03	0.040	NA	0.007	NA	0.031	1.2e-04	NA	6.9e-02	NA	7.2e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Eye problems/disorders: Glaucoma	9.4	11.1	18.3	3.4	1.8	3.6	4.0	0.9	3.1	4.0	3.8	2.9	4.3
Glaucoma (self-reported)	7.3	8.5	14.7	3.1	2.2	3.7	3.4	-0.3	3.1	2.8	3.1	1.8	3.8
Commuting to job workplace: Public transport	5.9	7.1	11.6	-3.3	-1.4	-3.1	-3.4	0.4	-3.0	-2.4	-3.3	-2.4	-2.3
Medication: Lansoprazole	4.5	5.1	8.8	-2.4	-1.4	-2.5	-3.0	-1.5	-1.6	-2.9	-2.0	-1.5	-2.9
Hair/balding pattern: Pattern 4	4.4	10.6	46.2	2.2	6.8	3.0	-1.8	1.3	4.3	2.2	2.0	-0.9	3.5
Breast Cancer	4.1	9.8	14.1	3.8	3.1	3.5	3.1	2.7	2.5	3.7	3.5	2.2	2.8
Medication: Omeprazole	4.1	4.9	11.8	0.6	2.3	3.4	2.5	0.2	2.5	1.6	3.4	1.8	1.1
Average weekly champagne plus white wine intake	4.1	5.6	17.4	1.5	2.5	2.6	1.7	-0.9	3.0	2.2	2.3	0.0	4.2
Mother’s age at death	4.1	5.1	11.4	-2.9	-1.4	-1.8	-2.4	-0.3	-2.4	-2.0	-3.4	-1.4	-2.9
Tinnitus: Yes, but not now, but have in the past	3.9	4.2	7.7	2.2	0.3	1.9	2.7	1.7	1.9	2.5	2.8	2.1	1.2
Guilty feelings	3.6	5.4	8.9	-1.7	-2.6	-2.7	-1.5	-0.5	-2.9	-2.5	-3.0	-2.2	-2.5
Bipolar Disorder (2018)	3.3	5.2	18.1	0.8	2.7	1.0	1.5	3.1	1.2	4.3	1.8	1.4	2.7
Ever had stillbirth, spontaneous miscarriage or termination	3.0	3.2	10.5	2.0	1.4	1.8	1.1	0.3	3.2	1.1	1.2	-0.1	2.8
Bipolar Disorder or Schizophrenia	2.9	7.0	20.6	2.3	3.1	1.5	1.6	3.7	1.5	4.5	1.4	1.4	3.2
Medication: Aspirin	2.9	3.8	8.8	2.1	2.8	2.0	1.0	0.5	1.5	2.3	3.0	1.4	1.6
Serious illness, injury or assault to yourself	2.8	3.4	6.0	1.9	1.1	2.5	1.9	-2.2	1.6	1.9	2.4	1.6	0.5
Hair/balding pattern: Pattern 3	2.7	4.1	13.7	1.2	-3.5	1.5	3.7	-1.2	0.7	1.3	1.3	2.4	0.6
Commuting to job workplace: Car/motor vehicle	2.7	3.1	5.7	1.5	1.7	2.2	1.6	-0.0	2.4	0.9	2.3	1.2	2.3
Medication: Aspirin	2.7	3.6	7.9	1.5	2.7	2.0	1.1	0.8	1.3	2.5	2.8	1.5	1.5
Impedance of leg (left)	2.6	12.5	31.6	-3.9	-4.7	-3.6	-0.4	0.5	-4.9	-2.3	-3.4	-1.2	-5.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.6	3.1	6.6	-2.0	-2.4	-2.2	-1.0	-1.1	-2.2	-0.3	-2.6	-0.5	-1.2
Allergy or Eczema	2.4	6.2	19.3	1.7	3.0	2.3	1.5	0.3	3.4	2.8	1.3	1.4	4.4
Other serious medical condition/disability diagnosed by doctor	2.4	3.1	6.1	2.3	1.4	1.9	1.4	-0.3	2.0	1.6	2.2	2.5	0.5
Impedance of leg (right)	2.4	11.7	29.8	-3.4	-4.3	-3.8	-0.7	0.6	-5.1	-2.2	-3.2	-1.2	-5.5
Worry too long after embarrassment	2.4	4.0	7.2	-1.9	-1.7	-2.3	-1.5	0.6	-2.0	-2.6	-2.4	-1.3	-2.7
Impedance of arm (right)	2.3	10.8	25.7	-4.4	-2.7	-4.3	-2.4	-0.0	-3.7	-1.2	-3.8	-1.5	-5.1
Number of live births	2.3	3.2	7.3	2.2	0.1	1.7	2.4	1.8	1.4	1.4	1.9	2.7	1.0
Chronic bronchitis/emphysema (mother)	2.2	2.6	10.0	0.1	0.7	-1.9	-2.0	0.8	-2.1	-0.2	-0.1	1.6	-3.2
Eye problems/disorders: None of the above	2.2	2.5	6.2	-1.8	-0.7	-1.4	-1.9	0.7	-0.2	-2.0	-2.5	-2.1	-0.2
Basal cell carcinoma (self-reported)	2.2	2.7	6.2	1.6	0.9	2.1	1.3	-1.4	2.5	0.4	1.6	-0.1	2.4
Taking other prescription medications	2.1	3.2	5.8	1.5	1.4	2.1	1.5	-0.8	2.4	2.4	1.8	1.3	1.9
Number of incorrect matches in round	2.1	3.5	11.6	1.2	3.0	1.3	0.5	3.4	1.8	1.6	1.5	0.2	1.8
Hair/balding pattern: Pattern 2	2.1	2.7	7.1	-2.7	1.1	-1.5	-2.5	1.9	-1.0	-1.7	-0.8	-1.4	-0.6
Gout (self-reported)	2.1	2.9	7.6	1.2	2.7	1.3	-0.1	0.1	2.2	2.1	0.8	-1.2	2.8
Impedance of whole body	2.1	10.6	28.6	-4.3	-3.5	-3.8	-1.0	0.7	-4.2	-1.1	-3.3	-0.9	-5.3
Sensitivity / hurt feelings	2.0	3.4	8.3	-1.8	-1.6	-2.0	-0.5	1.1	-1.9	-2.3	-2.4	-0.7	-2.9
Hayfever, allergic rhinitis or eczema	2.0	4.3	14.0	1.0	2.7	1.5	1.1	0.6	2.9	2.3	1.2	1.4	3.7
Hearing difficulty/problems with background noise	2.0	3.3	7.5	0.8	1.2	2.7	1.3	1.2	2.7	0.8	2.0	0.9	2.7
Illnesses of mother	2.0	2.5	6.5	1.3	-0.2	1.4	1.9	-1.1	2.5	1.4	1.1	0.6	2.5
Supplements: Vitamin C	2.0	2.3	8.1	-1.3	0.3	-1.4	-1.6	-1.0	-1.8	-0.4	-2.9	-1.7	-1.3
Lung cancer (father)	1.9	2.2	6.9	-0.6	0.8	2.1	1.0	0.9	2.4	0.7	1.1	-1.2	2.6
Number of full brothers	1.9	2.4	8.2	0.7	0.8	1.4	1.1	1.5	1.2	1.8	2.9	1.6	1.4
Age at first live birth	1.9	3.4	6.8	-2.4	-0.5	-2.5	-2.6	-0.6	-2.1	-1.0	-2.2	-1.9	0.5
Lupus	1.8	2.7	7.2	-1.3	-1.9	-2.7	-1.3	-0.0	-1.7	-1.0	-2.1	-1.7	-1.1
Schizophrenia (2014)	1.8	4.0	11.0	1.9	2.4	0.8	1.0	3.0	0.8	3.3	1.1	1.3	2.4
Number of treatments/medications taken	1.8	3.2	8.5	2.2	0.9	2.9	2.2	-1.0	1.9	1.4	2.0	1.3	0.9
High blood pressure (siblings)	1.8	2.7	7.4	2.7	2.3	2.3	0.6	-0.4	1.5	1.7	1.2	1.2	0.8
Number of children fathered	1.8	2.1	7.4	0.3	0.4	1.6	1.9	0.8	0.7	2.7	1.1	1.7	1.2
Osteoarthritis (self-reported)	1.8	2.3	6.1	1.3	-0.4	2.5	1.5	1.4	2.1	1.1	2.1	1.0	0.2
Medication: Blood pressure	1.8	3.4	8.8	2.5	2.1	3.0	0.5	0.6	2.5	0.5	1.8	0.2	2.0
Bipolar Disorder (2011)	1.7	1.7	4.3	0.7	1.7	-0.3	-0.1	2.1	-1.0	2.0	1.1	1.6	-0.2
Body Mass Index (BMI) (2010)	1.7	2.3	6.2	0.2	-1.3	-2.0	-1.8	-0.8	-2.5	-1.9	-0.8	-0.1	-1.8
Impedance of arm (left)	1.7	7.9	20.4	-4.0	-2.4	-3.6	-1.5	0.3	-3.1	-1.0	-3.0	-1.0	-4.5
Had other major operations	1.6	1.9	4.1	1.6	-0.3	1.9	1.6	-0.5	1.4	0.7	2.0	1.7	-0.1
Exposure to tobacco smoke outside home	1.6	2.1	4.9	0.1	1.1	2.0	2.2	1.6	1.3	1.4	1.3	0.7	1.6
Alzheimer’s Disease (in father)	1.5	1.6	6.6	0.5	0.2	0.8	1.7	0.0	-0.0	1.6	1.6	2.6	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.7	5.2	0.4	1.6	2.3	-0.3	0.8	2.2	-0.0	1.2	-1.1	1.1
Pulse rate, automated reading	1.5	4.9	10.2	3.2	-0.3	2.6	3.1	0.8	0.9	2.3	2.9	2.2	1.3
Breast cancer (self-reported)	1.5	1.8	3.9	1.7	-0.2	1.2	1.7	-0.3	0.9	2.0	0.8	1.8	1.7
Ever had prostate specific antigen (PSA) test	1.5	1.7	4.8	1.0	-1.4	-1.0	-0.7	-0.6	-0.5	-2.2	-1.9	-1.3	-1.2
Pain experienced in last month	1.5	2.6	9.8	-0.9	0.5	-1.3	-2.7	1.1	-0.4	-0.2	-1.7	-3.1	1.1
Relative age voice broke	1.4	2.1	5.9	-2.3	-0.1	-1.8	-1.5	-0.8	-1.4	-0.6	-0.8	-0.5	-2.4
Medication for pain relief, constipation, heartburn	1.4	2.3	6.5	-1.0	-0.4	-1.7	-2.2	1.3	-1.0	-1.3	-2.6	-1.8	-0.4
Leg fat-free mass (right)	1.4	7.3	21.3	2.5	4.0	2.1	-0.9	-0.4	4.0	0.4	3.0	0.6	4.6
Average weekly red wine intake	1.4	2.0	7.1	-1.6	1.2	-1.2	-2.7	-0.4	-0.5	-1.3	-1.4	-1.8	0.6
Long-standing illness, disability or infirmity	1.4	2.2	5.1	1.7	0.4	1.4	1.7	-0.0	1.5	2.3	1.2	1.9	1.3
Leg predicted mass (right)	1.4	7.6	22.0	2.5	4.0	2.2	-0.8	-0.4	4.0	0.5	3.0	0.7	4.7
Risk taking	1.4	2.0	8.1	0.3	2.4	0.8	-0.3	1.2	1.2	1.4	0.8	-0.4	2.8
Medication: Omeprazole (e.g. Zanprol)	1.4	1.8	5.4	-0.3	1.6	2.0	1.3	-0.7	1.2	0.9	2.3	1.0	0.1
Supplements: Calcium	1.4	1.5	3.9	1.3	-0.2	1.0	2.0	0.2	0.9	1.4	1.9	1.4	0.6
Schizophrenia (2018)	1.3	2.7	5.9	2.4	1.9	1.1	0.8	2.2	0.9	2.4	0.4	0.7	1.9
Verbal and Numeric Reasoning (VNR)	1.3	3.1	5.9	-1.9	-1.8	-1.5	-1.2	-2.4	-2.4	-1.6	-1.5	-0.6	-1.9
Average weekly spirits intake	1.3	1.6	3.2	-0.3	1.3	1.8	0.6	-0.3	1.8	1.5	1.3	-1.1	1.6
Pack years adult smoking proportion	1.3	2.0	5.8	1.2	0.9	1.2	1.8	1.2	0.4	1.5	2.4	1.8	0.4
Leg fat-free mass (left)	1.3	6.8	19.3	2.6	3.9	1.7	-1.2	-0.4	3.6	0.5	2.9	0.7	4.4
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	4.3	-1.2	-0.9	0.6	-0.4	-2.1	1.1	-0.8	-1.0	-2.1	0.7
Leg predicted mass (left)	1.3	7.0	20.3	2.7	3.9	1.8	-1.1	-0.4	3.6	0.5	2.9	0.6	4.5
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	5.2	1.4	-0.5	-1.8	-0.0	1.5	-2.3	0.6	-0.3	0.4	-1.6
Whole body water mass	1.3	7.2	23.7	2.7	3.9	2.0	-0.9	-0.1	3.3	0.1	3.1	0.2	4.9
Number of self-reported non-cancer illnesses	1.3	2.3	6.4	2.5	2.4	0.7	0.0	-1.0	0.8	2.1	0.8	1.6	1.2
Age started oral contraceptive pill	1.3	1.7	4.5	0.8	-0.2	-0.7	-0.4	-1.5	-2.1	-1.2	-1.8	0.2	-1.9
Heel T-Score	1.2	9.4	17.2	-3.1	-1.8	-3.5	-4.2	-2.9	-2.6	-3.6	-3.5	-3.1	-1.4
Diabetes (mother)	1.2	1.6	3.8	0.1	-1.1	-1.6	-1.6	-0.9	-1.9	-0.6	-1.4	-1.2	-1.1
Age when periods started (menarche)	1.2	2.8	8.9	-0.1	2.1	-0.8	0.2	2.9	-1.1	1.7	1.0	3.0	-1.1
Qualifications: CSEs or equivalent	1.2	1.6	4.2	-1.1	-0.9	-1.6	-0.6	0.8	-2.0	-0.4	-0.7	1.4	-2.0
Diverticular disease/diverticulitis (self-reported)	1.2	1.5	3.9	-1.4	-1.1	0.1	-0.9	-1.6	0.7	-2.0	-1.0	-1.7	-0.2
Mouth/teeth dental problems: Dentures	1.2	2.0	7.0	1.7	1.4	2.0	-0.1	-2.7	1.9	0.2	0.5	-0.4	0.8
Whole body fat-free mass	1.2	6.9	22.3	2.6	3.9	2.0	-1.0	-0.1	3.3	-0.0	3.0	0.1	4.7
Commuting to job workplace: Walk	1.2	1.3	6.2	-1.2	0.4	-0.3	-1.8	0.0	-0.3	-0.8	-0.9	-2.5	0.3
Supplements: Fish oil (including cod liver oil)	1.2	1.5	7.1	-1.2	-2.7	-0.2	0.4	-0.5	-1.0	-1.6	-0.3	-1.1	-1.3
Illnesses of father: High blood pressure	1.2	1.5	3.9	-1.4	-2.0	-1.4	-0.2	0.7	-1.8	-0.4	-1.0	-1.1	-1.1
Ever smoked	1.2	2.1	7.1	-1.7	-1.0	-1.2	-1.2	-2.7	-0.7	-1.8	0.1	-0.4	-1.8
Cholesterol lowering medication	1.2	1.8	7.0	1.3	-0.3	-0.8	-1.6	-1.3	-0.5	-2.6	-1.2	-1.1	-1.0
Severe depression (siblings)	1.1	1.3	3.1	-1.8	0.2	-1.4	-1.4	1.4	-0.4	0.9	-1.2	-0.3	-1.1
Hand grip strength (right)	1.1	2.9	8.0	0.6	1.7	-0.8	-0.7	2.6	-2.0	0.6	1.3	2.8	-1.9
Mouth/teeth dental problems	1.1	1.7	3.7	-1.0	-1.5	-1.5	-0.4	1.9	-1.6	-1.2	-1.4	-0.9	-1.1
Allergy	1.1	2.6	6.3	-1.6	-1.8	-0.7	-0.9	0.2	-2.3	-2.1	-0.7	-1.7	-2.5
Medication: Simvastatin	1.1	1.7	4.5	-0.7	-0.7	-1.1	-1.8	-0.7	-0.3	-2.1	-1.8	-1.6	-0.6
Neuroticism score	1.1	2.2	4.6	-1.0	-0.9	-1.2	-1.3	0.2	-1.2	-2.1	-2.1	-1.5	-2.0
Trunk fat-free mass	1.1	6.5	22.5	2.3	4.0	1.9	-1.0	0.3	2.9	-0.1	2.9	-0.2	4.7
Pulse wave Arterial Stiffness index	1.1	1.3	2.5	-1.0	-1.1	-0.8	-1.2	-0.9	-1.0	-1.6	-1.2	-1.5	-1.1
Trunk predicted mass	1.1	6.3	21.9	2.3	3.9	1.8	-1.0	0.3	2.8	-0.1	2.9	-0.2	4.7
Tense / ‘highly strung’	1.1	1.7	3.9	-0.0	1.7	-1.1	-1.9	2.0	-1.2	-0.7	-1.0	-0.8	-1.5
Arm fat-free mass (right)	1.1	5.4	18.5	2.7	2.7	2.0	-0.4	-0.6	2.8	-0.4	2.9	0.1	4.3
Pulse wave peak to peak time	1.1	1.3	2.1	0.8	1.3	0.8	1.0	1.0	1.0	1.4	1.4	1.3	1.1
Angina (self-reported)	1.1	1.4	4.0	2.0	1.8	0.1	0.0	1.1	0.4	1.7	1.5	0.7	0.1
Arm predicted mass (right)	1.1	5.8	17.0	2.9	3.0	2.1	-0.3	-0.2	2.8	-0.2	3.2	0.6	4.1
Illnesses of siblings: Diabetes	1.1	1.4	3.9	0.4	-0.8	-2.0	-0.6	0.3	-2.0	0.1	-0.9	0.7	-1.9
Smoking status: Previous	1.1	1.6	5.1	-0.6	-1.8	-0.5	-0.9	-2.1	0.4	-2.3	-0.7	-0.7	-1.1
Basal metabolic rate	1.1	6.2	19.5	2.6	3.5	1.7	-1.1	-0.4	3.2	-0.0	2.9	0.3	4.4
Irritability	1.1	1.9	9.6	-1.4	0.4	-0.1	-1.2	-1.5	-0.0	-0.6	-1.5	-3.1	1.0
Pack years of smoking	1.1	1.6	4.1	1.2	0.7	1.2	1.7	0.8	0.4	1.5	2.0	1.6	0.3
Reaction Time	1.0	2.0	7.2	-0.6	2.0	1.5	0.1	0.6	1.9	0.8	0.6	-0.9	2.7
Coronary Artery Disease (CAD)	1.0	1.2	4.1	0.8	2.0	1.1	-0.2	-1.0	1.4	0.5	1.0	-0.5	1.4
HDL Cholesterol	1.0	1.7	4.9	-0.2	1.4	2.2	0.3	-0.7	1.7	-0.6	0.8	-2.0	1.2
Pulse rate	1.0	1.6	5.6	1.2	-0.2	0.9	0.9	2.4	-0.2	1.6	1.8	0.9	0.9
Ever highly irritable/argumentative for 2 days	1.0	1.2	4.3	-0.1	0.1	1.2	0.9	0.7	2.0	0.6	0.2	-0.6	2.1
Age at last live birth	1.0	1.4	4.4	-1.5	0.7	-1.2	-2.1	0.6	-0.4	0.1	-1.3	-0.9	1.5
Illnesses of father: Heart disease	1.0	1.4	3.9	1.3	2.0	1.1	-0.9	-1.3	1.6	-0.6	0.7	-0.9	0.2
Loneliness, isolation	1.0	1.3	8.5	-0.4	-0.8	-0.6	-0.7	-0.2	-1.4	-0.9	-0.5	-0.7	-2.9
Qualifications: nursing, teaching	1.0	1.5	5.5	-1.3	-0.7	-0.6	-0.1	-0.9	-1.9	-0.0	-1.6	0.1	-2.4
Mineral and other dietary supplements	1.0	1.4	5.7	0.9	2.4	0.4	-0.7	-0.2	1.5	1.0	-0.0	0.6	1.7
Alcohol drinker status: Previous	1.0	1.2	4.0	-0.7	-0.7	-0.8	-1.0	-1.1	-1.3	-0.5	-1.2	-0.6	-2.0
Arm predicted mass (left)	1.0	5.0	16.3	2.7	2.8	1.8	-0.7	-0.5	2.6	-0.4	2.9	0.4	4.0
Schizophrenia vs Biploar Disorder	0.9	1.1	2.5	-1.2	-0.5	-1.6	-1.1	-0.9	-0.6	-1.4	-1.5	-0.4	-0.7
Hand grip strength (left)	0.9	2.4	6.3	-0.4	1.1	-1.2	-1.2	2.5	-2.2	-0.1	0.3	1.9	-2.3
Systolic blood pressure, automated reading	0.9	2.6	8.8	-0.2	-0.3	1.4	-0.9	-2.2	1.3	-0.9	-1.1	-3.0	2.5
Fed-up feelings	0.9	1.6	3.4	-1.5	-1.2	-1.4	-0.8	-0.1	-1.4	-1.2	-1.4	-1.0	-1.8
Medication: Atenolol	0.9	1.2	2.7	1.1	-0.1	1.6	-0.1	-1.3	1.2	-1.0	-0.2	-1.6	1.0
Had menopause	0.9	1.1	3.1	-0.5	-0.9	-0.7	-1.4	-0.8	-1.0	-1.2	-0.8	-0.5	-1.8
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	4.4	-0.0	2.1	0.1	-0.9	-0.1	1.3	1.6	-0.2	-0.2	1.7
Illnesses of siblings	0.9	1.2	6.7	-2.6	-0.7	-1.3	-0.9	-0.2	-0.7	-1.1	-0.4	-0.7	-0.1
Falls in the last year	0.9	1.2	6.8	0.6	-0.9	-0.2	1.7	-0.7	0.3	0.6	0.1	2.6	-0.5
Forced expiratory volume in 1-second (FEV1)	0.9	3.0	12.1	-1.3	1.1	-1.8	-2.3	3.5	-1.1	-1.0	-1.0	0.3	-1.9
Pulse wave reflection index	0.9	1.1	3.5	-0.1	-0.2	-1.0	-1.1	-0.9	-0.5	-1.8	-1.9	-0.6	-1.0
Medication: Paracetamol	0.9	1.6	5.2	-0.1	-1.2	1.2	2.3	-1.1	0.9	0.3	1.8	1.3	-0.0
Shortness of breath walking on level ground	0.9	1.0	3.0	-0.0	0.4	-1.5	-0.7	0.6	-1.2	0.0	-0.2	1.6	-1.7
Medication for cholesterol	0.9	1.3	5.3	-2.3	-1.6	-1.6	0.1	-0.1	-1.2	-0.1	-1.0	-0.8	-0.3
Medication: Paracetamol	0.9	1.4	4.2	0.1	-1.1	1.1	2.1	-0.8	0.5	0.3	1.9	1.7	-0.2
Arm fat-free mass (left)	0.9	4.7	15.7	2.6	2.5	1.8	-0.5	-0.7	2.6	-0.3	2.8	0.3	4.0
BMI	0.8	4.5	10.2	3.2	2.2	1.2	-1.2	-1.8	2.8	-0.1	2.5	0.8	3.0
Cardiovascular Disease	0.8	2.6	13.4	2.6	3.7	1.1	-0.2	0.8	0.4	0.7	1.3	0.6	1.2
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.7	-0.9	-1.0	-1.0	-0.3	-0.0	-1.5	-0.1	-0.3	1.5	-1.9
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	4.5	2.1	0.3	-0.2	-0.1	-1.3	0.1	0.1	1.1	1.1	-0.1
Angina	0.8	1.0	3.1	1.8	1.5	-0.1	-0.1	0.9	0.5	1.4	1.2	0.5	-0.1
Diabetes (father)	0.8	1.0	2.4	-1.1	-0.4	-1.2	-1.6	-0.1	-0.8	-0.5	-0.6	-1.0	-1.6
Maternal smoking around birth	0.8	1.2	3.3	-0.4	1.8	0.8	-0.0	1.0	-0.3	0.8	1.7	1.8	0.0
Stomach or abdominal pain in last month	0.8	0.9	2.2	-1.0	-0.0	0.4	1.4	0.4	-0.6	1.0	1.1	1.5	-1.1
Body mass index (BMI)	0.8	3.4	8.3	2.9	0.7	1.3	-0.2	-2.6	2.5	-0.1	2.1	1.1	2.3
Alcohol intake versus 10 years previously	0.8	1.2	5.5	-0.2	-1.4	-0.6	-0.7	-0.7	-0.8	-1.2	0.4	0.6	-2.4
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	3.1	-0.7	0.7	-0.9	-1.2	-1.3	-0.5	-0.3	-0.4	-1.8	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	5.6	-1.1	-0.2	-1.2	-0.4	0.3	-1.2	-0.4	-1.1	1.1	-2.4
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	2.4	-1.0	-1.6	-1.3	-0.8	-1.3	-1.5	-0.6	-0.9	-0.1	-1.4
Mouth/teeth dental problems: Loose teeth	0.8	1.0	4.3	1.6	0.8	0.9	-0.3	-1.2	0.4	0.0	2.1	-0.1	0.2
Mean time to correctly identify matches	0.8	1.5	3.8	-1.0	1.6	1.0	-0.5	-0.7	1.5	0.0	-0.3	-1.8	1.9
Ever had bowel cancer screening	0.8	1.0	3.7	0.9	0.0	1.6	0.5	-1.1	1.9	-0.7	-0.4	-0.4	0.4
Eye problems/disorders: Cataract	0.8	0.9	3.8	-1.3	-0.2	-0.7	0.3	-0.6	-1.4	0.8	0.1	0.8	-1.9
Back pain experienced in last month	0.8	1.1	2.9	0.8	-0.6	1.2	1.2	0.7	1.7	-0.5	1.4	1.2	0.3
Osteoporosis (self-reported)	0.8	1.0	3.3	-0.0	-0.8	-0.7	-0.5	1.8	-0.9	-1.3	0.2	-0.1	-1.5
Wears glasses or contact lenses	0.8	0.9	3.0	0.5	-0.0	1.3	-0.4	-0.5	1.1	-1.5	-0.3	-1.7	-0.1
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.3	-0.1	0.8	1.4	0.8	1.3	1.5	0.3	1.2	-0.2	0.4
Unable to work because of sickness or disability	0.8	1.1	2.3	1.2	1.3	1.3	0.2	-0.1	1.5	-0.4	1.0	1.5	0.1
Myopia	0.8	1.1	3.0	-1.7	0.5	-0.3	-1.2	0.4	0.8	0.2	-0.5	-1.7	1.6
Mean Putamen Volume	0.7	0.8	2.7	0.4	0.3	1.1	-0.1	-0.6	1.6	-0.1	0.3	-1.2	1.3
Fasting Glucose	0.7	0.8	3.5	-1.9	-1.1	-0.4	0.2	-1.2	-0.3	-0.5	-0.6	-1.0	0.3
HbA1C	0.7	0.7	2.8	0.9	-1.7	-0.9	0.3	-0.3	-1.0	1.0	0.4	0.6	-0.6
Type 2 Diabetes (T2D) (2012)	0.7	0.8	3.7	0.2	-0.8	-1.9	-1.3	-0.2	-0.9	-0.5	-0.4	-0.2	-0.6
Lung FEV1/FVC ratio	0.7	3.6	7.5	-2.4	-0.3	-1.7	-2.7	0.6	-1.5	-1.8	-2.6	-2.1	-1.7
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.4	0.6	-0.4	1.4	1.5	-1.0	0.2	0.9	1.1	1.2	-0.1
Supplements: Glucosamine	0.7	0.9	3.9	0.1	-1.4	-0.6	0.1	-0.1	-1.2	-1.0	-0.2	0.4	-2.0
Past tobacco smoking	0.7	1.3	4.7	0.7	1.3	0.4	0.6	2.2	0.0	1.7	-0.1	-0.1	1.6
Alcohol usually taken with meals	0.7	1.2	3.2	1.3	1.7	1.1	-0.0	0.3	1.5	-0.2	-0.1	-0.6	1.8
Weight	0.7	3.3	7.5	2.3	1.8	0.9	-1.3	-1.8	2.4	-0.7	2.1	0.5	2.7
Time employed in main current job	0.7	0.8	2.9	-0.0	-0.9	-0.7	0.7	-0.3	-1.7	1.1	0.4	1.2	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.4	8.2	-0.9	0.6	-1.3	-2.2	2.9	-0.8	-1.8	-1.0	-0.6	-1.6
Breastfed as a baby	0.7	0.8	3.5	-1.0	-1.0	-0.7	-1.3	0.4	0.2	-1.9	0.1	-0.2	-0.7
Peak expiratory flow (PEF)	0.7	1.7	6.6	-0.1	0.4	-1.2	-1.4	2.6	-1.1	0.3	-0.6	1.7	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	4.0	-0.7	0.4	-0.9	0.1	-0.2	-1.0	0.8	0.2	2.0	-1.2
Health satisfaction	0.7	0.9	2.3	1.2	1.5	1.0	0.2	-1.1	1.1	0.3	0.9	0.5	0.6
Emphysema/chronic bronchitis	0.7	0.8	1.7	0.3	1.2	1.0	0.0	-1.3	1.2	0.6	0.9	0.7	1.0
Medication: Ibuprofen	0.7	0.9	4.0	-0.2	-0.3	-0.6	0.3	0.4	-1.6	1.1	-0.4	2.0	-0.4
Alcohol intake frequency.	0.7	1.6	6.7	1.1	-1.9	-0.4	1.0	-0.7	-0.7	-0.4	-0.1	1.2	-2.6
Mood swings	0.7	1.3	3.9	-1.3	-0.2	-0.2	-0.9	-1.8	0.0	-1.5	-1.3	-2.0	0.1
Friendships satisfaction	0.7	0.9	2.5	1.1	1.0	1.0	0.5	0.5	0.6	1.4	0.9	0.3	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.6	0.5	1.1	0.1	0.6	-1.5	0.9	1.6	0.6	0.1	0.6
Medication: Gliclazide	0.7	0.8	1.6	1.2	-1.3	1.2	1.1	0.3	0.8	0.5	0.7	0.7	0.2
Medication: Bendroflumethiazide	0.7	1.0	3.9	0.3	-0.2	2.0	0.8	-0.9	1.2	0.2	0.4	-0.6	1.6
Fractured/broken bones in last 5 years	0.7	0.9	3.1	1.4	1.8	1.1	0.2	-0.5	1.0	0.5	0.1	0.4	0.8
Vascular/heart problems diagnosed by doctor	0.7	2.0	5.1	-1.8	-2.2	-2.0	0.4	0.2	-1.6	-0.2	-0.7	0.8	-1.9
Worry (Nagel 2018)	0.6	1.2	8.6	0.5	1.5	0.2	-0.7	2.9	0.7	-0.4	0.1	0.2	-0.2
Ulcerative Colitis (UC)	0.6	1.2	2.7	1.1	0.2	1.6	1.3	0.7	1.3	0.9	0.9	0.3	1.5
Blood Red Count	0.6	5.3	11.8	-0.7	-2.2	-2.2	-3.3	0.1	-2.3	-3.4	-1.8	-0.7	-3.4
Smoking Status	0.6	1.4	6.9	0.0	-0.4	0.1	-0.9	-0.5	-1.1	-1.8	0.7	1.0	-2.6
Ever had hysterectomy (womb removed)	0.6	0.6	1.7	-0.5	1.3	1.1	-0.0	-0.9	0.4	0.7	1.0	-0.0	0.8
Waist circumference	0.6	2.1	5.1	1.7	1.1	0.5	-1.3	-2.3	2.1	-1.0	1.0	0.2	1.9
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	2.9	0.0	-1.7	0.1	-0.2	-0.1	0.1	-1.7	-0.6	-1.2	-0.6
Medication: Cholesterol lowering	0.6	0.9	2.6	0.0	1.2	1.0	-0.3	-0.2	1.0	0.7	0.5	-1.6	1.4
Arm fat mass (right)	0.6	2.6	6.9	2.2	0.6	0.2	-1.0	-2.6	2.1	-0.2	1.8	1.0	1.9
Illnesses of father: None of the above (group 1)	0.6	0.8	2.7	-0.7	-1.6	-1.1	0.5	0.2	-1.2	0.4	-1.1	0.4	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	9.4	0.1	1.4	0.0	-0.9	3.1	-0.2	-0.1	-0.5	0.1	-0.6
Arm fat mass (left)	0.6	2.4	5.0	2.1	0.6	0.2	-1.0	-2.2	2.1	-0.4	2.0	1.0	1.8
Ever taken oral contraceptive pill	0.6	0.6	2.9	-0.1	1.7	-0.4	-1.0	1.3	-0.2	0.4	-0.6	0.3	0.0
Financial situation satisfaction	0.6	0.7	2.3	1.5	-0.8	-0.1	0.7	1.2	-0.2	0.4	0.7	1.4	-0.1
Pain type(s) experienced in last month: Hip pain	0.6	0.7	4.3	0.1	-2.1	0.3	0.8	-0.3	0.1	-0.9	-0.9	0.0	-0.7
Number of operations (self-reported)	0.6	0.8	3.3	0.9	0.9	0.9	0.1	-0.6	1.8	0.8	1.0	0.8	-0.1
Depressed Affect (Nagel 2018)	0.5	1.1	2.8	-0.2	-1.5	-0.3	0.0	-1.1	-0.3	-1.7	-0.8	-1.1	-1.5
Depression (Nagel 2018)	0.5	0.7	3.6	0.6	0.1	-0.0	0.8	0.6	0.2	0.4	0.9	1.9	-0.9
Neuroticism (Nagel 2018)	0.5	1.2	2.8	-0.8	-0.7	-0.9	-0.6	1.2	-0.4	-1.7	-1.1	-1.3	-1.5
Alzheimer’s Disease (including proxy)	0.5	0.7	4.1	-0.4	-1.2	0.2	2.0	-0.4	-0.7	0.5	-0.0	0.8	0.0
Age at First Birth	0.5	0.7	1.8	-1.2	1.3	-0.6	-0.9	-0.4	-0.9	0.0	-1.0	-0.4	-0.5
Crohns Disease (2012)	0.5	0.8	2.7	-1.4	0.6	-0.8	0.3	0.5	0.1	1.6	0.3	1.3	0.3
Triglycerides	0.5	0.8	3.3	1.4	-0.4	-0.3	0.1	0.6	0.0	1.8	0.2	1.1	0.8
Ulcerative Colitis	0.5	0.8	2.8	0.4	0.3	0.9	0.2	-0.0	1.4	0.3	0.0	-1.2	1.7
Chronotype (morning person)	0.5	1.1	2.9	0.2	-1.1	0.0	-0.1	-1.1	1.7	-1.4	0.1	-1.6	0.7
Townsend deprivation index at recruitment	0.5	0.6	3.0	0.1	1.7	-0.2	-0.3	0.5	-0.2	1.0	1.2	0.7	0.4
Current tobacco smoking	0.5	0.8	2.1	-0.2	1.2	1.1	-0.5	0.1	-0.4	-0.7	1.1	0.8	-1.4
Average weekly fortified wine intake	0.5	0.5	2.6	0.2	1.4	-0.2	-1.6	0.2	-0.1	0.2	-0.5	-0.7	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	3.0	0.2	0.0	-0.4	0.3	1.2	-0.4	0.2	0.2	1.7	-1.4
High blood pressure	0.5	1.4	3.2	1.3	1.6	1.7	-0.5	-0.5	1.3	-0.6	0.3	-1.2	1.8
Forced vital capacity (FVC)	0.5	1.8	11.1	-0.2	1.2	-0.9	-1.2	3.3	-0.5	-0.5	0.0	0.7	-1.5
Worrier / anxious feelings	0.5	1.0	3.1	-1.8	-0.3	-0.5	-1.1	1.2	0.2	-1.3	-0.9	-1.1	-0.3
Prospective memory result	0.5	0.6	4.3	0.4	0.5	0.1	0.4	-0.2	0.5	2.1	0.1	0.4	0.8
Exposure to tobacco smoke at home	0.5	0.6	2.5	0.7	0.1	1.1	1.6	0.1	0.3	0.7	0.9	-0.2	0.5
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.9	-1.1	0.0	-0.6	0.2	0.2	-0.8	1.4	0.8	1.0	0.6
Leg fat percentage (right)	0.5	1.7	6.5	2.1	-1.7	-0.7	-0.5	-2.6	0.1	-1.3	0.5	0.8	-0.3
Migraine (self-reported)	0.5	0.6	2.3	1.5	-0.3	0.1	0.7	-0.9	0.1	-0.2	-1.3	-0.5	0.8
Medication: Allopurinol	0.5	0.6	2.2	-0.8	1.5	0.2	-0.2	0.1	0.5	1.5	0.1	-0.5	0.8
Medication: Seretide 50 evohaler	0.5	0.6	1.8	-0.3	0.7	-1.4	-0.7	-0.2	-1.2	1.0	-0.5	0.6	-0.2
Had major operations	0.5	0.6	1.9	-1.1	-0.6	-1.1	-0.4	-0.7	-0.7	0.0	0.2	0.4	-1.4
Leg pain on walking	0.5	0.6	2.0	-1.2	-0.2	-0.4	-0.5	-0.5	-0.4	-1.1	-0.6	-0.5	-1.4
Hypertension (Self-reported)	0.5	1.4	3.1	1.6	1.8	1.8	-0.2	-0.2	1.2	-0.6	0.5	-0.7	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.5	-0.6	1.0	0.9	0.2	0.3	1.1	0.2	1.2	0.9	-0.2
Smoking status: Current	0.5	0.8	2.2	0.1	1.5	1.0	-0.5	0.2	-0.3	-0.5	1.1	1.0	-1.3
High cholesterol (Self-reported)	0.5	0.8	2.4	0.8	1.4	0.3	-1.3	-0.5	0.1	-0.9	-0.5	-1.5	-0.2
Medication: Lisinopril	0.5	0.6	1.1	0.1	0.7	1.0	-0.8	-0.1	1.0	-1.0	0.3	-1.0	0.8
Leg fat percentage (left)	0.5	1.7	7.2	1.8	-1.8	-0.6	-0.3	-2.7	0.3	-1.3	0.4	0.8	-0.2
Average weekly beer plus cider intake	0.5	0.7	3.5	0.6	-1.2	-0.2	0.7	-0.5	-1.0	0.2	0.5	1.9	-0.3
Diastolic blood pressure, automated reading	0.5	1.6	4.9	0.7	-1.1	0.4	-0.9	-2.2	0.3	-1.2	-0.9	-2.0	1.6
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.9	0.7	1.1	-0.2	0.3	-0.3	-0.2	1.4	1.1	1.1	0.4
Ovarian Cancer	0.4	0.5	3.1	-0.6	1.8	0.6	-0.3	0.1	0.3	0.3	0.8	0.5	-0.0
Neuroticism (2016)	0.4	0.6	2.0	-0.9	-1.3	0.1	0.3	-1.4	0.2	-0.2	-0.6	-1.0	0.0
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.4	1.4	-0.3	0.5	0.0	0.1	1.0	1.0	0.9	0.6	1.5
Lung FVC	0.4	2.0	8.8	-0.4	-0.1	0.2	-0.2	2.7	-0.6	-1.3	-1.1	0.1	-3.0
Neuroticism	0.4	0.8	3.8	0.3	-0.5	-0.6	-0.5	0.3	-0.7	-0.9	-1.4	-0.5	-1.9
Supplements: Zinc	0.4	0.5	1.5	0.0	1.1	0.4	-0.2	1.1	-0.1	1.2	-0.2	-0.3	0.8
Medication: Levothyroxine sodium	0.4	0.6	4.8	0.2	-0.5	0.2	0.1	-2.2	0.2	-0.4	0.3	-0.8	0.3
Sitting height	0.4	3.0	9.5	1.3	2.2	2.0	-0.4	1.6	1.8	0.2	1.8	-0.8	3.1
High blood pressure (mother)	0.4	0.6	2.2	-1.0	0.5	0.7	-0.3	1.5	-0.0	-1.1	-0.2	-0.7	0.0
Nervous feelings	0.4	0.7	2.0	-0.4	0.3	-0.3	-1.3	1.0	0.4	-1.4	-0.9	-0.7	-0.9
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	2.3	-1.5	0.8	-0.7	-1.2	1.1	-0.1	-0.5	0.1	0.0	-0.3
Heart attack	0.4	0.5	1.4	0.7	0.9	-0.3	0.2	-0.4	-0.3	1.2	1.0	1.0	0.1
Pain all over the body in last month	0.4	0.4	1.2	0.0	0.5	-0.2	-0.4	1.0	-0.5	0.1	0.7	1.1	-1.0
Medication: Ramipril	0.4	0.5	1.0	1.0	0.5	-0.2	-0.7	1.0	0.3	-1.0	-0.3	-0.9	-0.9
Arm fat percentage (right)	0.4	1.7	8.5	1.7	-0.3	-0.4	-1.0	-2.9	1.4	-0.0	1.1	0.9	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	2.9	-0.9	0.7	-0.3	-0.3	0.5	-0.8	0.3	0.1	0.7	-1.7
Noisy workplace	0.4	0.5	2.1	0.3	-1.0	-0.7	-0.7	-1.4	-0.4	-0.8	-0.0	-0.4	-0.6
Length of working week for main job	0.4	0.5	1.0	-1.0	-0.1	-0.9	-0.7	0.3	-0.9	-0.7	-0.4	0.1	-0.9
Loud music exposure frequency	0.4	0.4	1.1	0.8	0.9	-1.0	-0.7	0.6	-0.7	-0.3	-0.4	-0.4	0.1
Blood clot in the leg (DVT)	0.4	0.6	1.8	1.1	-0.7	0.3	1.0	-1.3	0.6	0.5	-0.1	-0.2	0.7
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.6	-0.4	-1.3	-1.0	0.3	0.2	-0.8	-0.9	-0.6	1.1	-1.1
Birth weight	0.4	0.9	3.1	-1.8	-0.1	-1.2	-0.3	-1.0	-0.9	-0.6	-1.3	0.3	-0.9
Forced vital capacity (FVC), Best measure	0.4	1.4	9.2	0.1	1.1	-0.5	-1.1	3.0	-0.3	-0.7	0.3	0.3	-1.1
Body fat percentage	0.4	1.6	8.2	1.5	-1.4	-0.7	-0.8	-2.9	0.8	-0.9	0.5	1.0	-0.3
Comparative body size at age 10	0.4	1.1	2.9	1.7	1.1	1.6	0.1	-0.1	1.5	-0.9	0.5	0.8	0.7
Qualifications: College or University degree	0.4	1.1	2.8	-0.9	1.1	-1.1	-1.1	-0.3	-0.6	0.6	-1.7	-1.2	1.4
Heart disease (mother)	0.4	0.5	2.8	-1.2	0.4	-0.3	-1.7	-0.6	-0.5	-0.3	-0.2	0.0	-0.6
Whole body fat mass	0.4	1.8	5.3	2.0	0.2	-0.0	-1.1	-2.3	1.8	-0.8	1.2	0.8	1.2
Leg fat mass (right)	0.4	1.7	5.4	2.3	-0.2	-0.0	-0.9	-2.3	1.2	-1.0	1.2	0.6	1.1
Number of full sisters	0.4	0.5	1.6	-0.1	1.2	0.1	-0.5	0.4	-0.4	-0.1	0.5	1.1	-1.2
Suffer from ‘nerves’	0.4	0.7	2.7	1.2	0.9	0.1	-0.5	1.6	0.3	-0.1	-0.6	0.2	-1.0
Overall health rating	0.4	0.9	2.9	1.7	0.7	1.1	0.4	-1.1	0.8	0.3	1.2	1.0	-0.2
Chest pain or discomfort	0.4	0.6	1.4	-0.7	0.8	-1.0	-1.2	0.4	-0.4	0.1	0.5	0.4	-1.2
Knee pain experienced in last month	0.4	0.6	2.7	-0.5	0.2	-0.1	-1.0	-0.6	0.1	-1.6	-0.5	0.8	-0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.8	-0.8	0.4	-1.7	-1.5	0.2	-1.3	-0.9	0.8	0.3	-0.5
Arm fat percentage (left)	0.4	1.7	6.4	1.9	-0.1	-0.2	-0.7	-2.5	1.6	-0.1	1.4	1.2	0.8
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.8	1.1	1.3	-0.8	-0.5	-0.5	-0.2	0.6	0.4	0.1	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.3	-0.1	1.1	0.5	0.4	0.3	0.6	0.9	0.9	1.5	0.5
Miserableness	0.4	0.7	3.0	0.1	-1.7	0.1	0.2	-0.7	-0.1	-1.0	-1.0	-0.8	-0.9
Ever depressed for a whole week	0.4	0.5	1.4	0.8	-1.0	0.6	0.3	-0.2	1.2	-1.2	0.5	0.2	-0.1
Commuting to job workplace: Cycle	0.4	0.5	4.0	-0.3	0.1	0.1	0.2	-2.0	0.4	-0.1	0.1	-0.1	0.5
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.5	0.8	-0.5	0.5	0.8	-1.2	0.8	0.5	0.1	-0.4	0.9
Leg fat mass (left)	0.4	1.7	5.4	2.2	-0.3	0.1	-0.7	-2.3	1.3	-1.1	1.2	0.7	1.1
Irritable Bowel Disease (IBD)	0.3	0.8	2.6	0.1	0.2	0.9	0.6	0.4	1.2	1.2	0.8	0.4	1.6
Major Depression (MDD)	0.3	0.4	1.3	0.8	1.2	0.1	-0.1	0.7	0.4	-0.5	-0.1	-0.8	-0.1
Primary Biliary Cirrhosis	0.3	0.5	2.4	0.1	-1.5	0.1	0.3	-0.0	-0.2	-0.5	-0.4	-1.3	-0.1
Rheumatoid Arthritis	0.3	0.5	1.2	-0.1	-1.1	0.1	0.8	0.5	0.7	-1.1	-0.6	-0.2	-0.7
Blood White Count	0.3	1.9	4.3	2.1	1.5	1.1	0.7	1.1	0.4	1.8	1.7	1.6	0.7
Waist Hip Ratio (WHR)	0.3	1.2	5.0	-0.1	0.9	-0.9	-2.2	0.0	0.1	-1.9	-0.5	-0.7	-1.0
Systolic Blood Pressure	0.3	1.6	6.7	-0.1	1.2	1.2	-0.5	-0.6	0.8	0.5	-0.6	-2.0	2.6
Respiratory disease	0.3	0.8	1.8	1.2	0.5	-1.3	-1.0	0.5	0.1	0.8	-0.6	1.3	0.2
Relative age of first facial hair	0.3	0.5	1.5	-1.1	0.6	-0.6	-0.9	0.3	-0.6	0.1	-0.6	0.0	-1.2
Medication for hormone replacement therapy	0.3	0.3	1.4	-0.1	-0.4	0.4	0.1	-0.6	0.3	1.2	0.8	-0.1	0.1
Vitamin and mineral supplements	0.3	0.4	1.2	0.2	-0.6	-0.3	1.1	-0.5	0.3	0.6	0.7	1.0	-0.0
Medication: Co-codamol	0.3	0.4	1.8	1.4	-0.3	0.2	0.5	-0.3	0.7	0.1	0.0	0.3	0.8
Trunk fat percentage	0.3	1.3	6.5	1.1	-1.0	-0.7	-1.1	-2.5	0.9	-0.7	0.3	1.0	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.2	0.1	-0.2	-1.2	-1.5	-0.6	0.2	-1.4	-1.0	-0.6	-0.2
Chronic bronchitis/emphysema (father)	0.3	0.3	1.0	-0.2	0.5	0.3	-1.0	0.1	0.8	-0.7	0.6	-0.5	0.6
Trunk fat mass	0.3	1.4	5.2	1.5	0.0	-0.3	-1.4	-2.3	1.4	-0.9	0.9	0.7	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	2.6	-0.3	-0.2	-1.0	-1.3	-0.5	0.1	-1.6	-0.4	-0.4	-0.5
Financial difficulties in last 2 years	0.3	0.4	1.0	-1.0	-0.5	-0.5	0.3	-0.1	-0.9	0.6	-0.4	-0.1	-1.0
Hip circumference	0.3	1.5	4.3	1.1	1.0	0.7	-0.9	-1.6	1.8	-0.5	1.0	0.2	2.1
Asthma	0.3	0.5	2.4	0.8	0.3	-1.6	-1.0	-0.2	0.1	0.6	-0.5	0.6	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.5	0.0	-0.6	-0.4	0.4	0.2	-1.2	0.3	-0.7	1.2	-0.4
Standing height	0.3	2.5	7.7	-1.1	2.7	-0.5	-2.8	1.6	0.3	-1.4	0.5	-1.4	1.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.0	-0.2	-0.1	-1.0	-0.8	-1.0	-0.9	-0.9	-0.5	-0.1	-0.9
Medication: Amlodipine	0.3	0.5	1.1	1.0	0.2	1.0	0.6	-0.7	0.3	1.0	0.3	-0.5	0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.1	0.4	-0.5	-0.4	-0.3	-0.8	0.9	0.2	0.3	-0.6	1.1
Neck or shoulder pain in last month	0.3	0.4	2.4	-0.6	0.7	-0.3	0.1	-0.5	-0.3	-0.5	-0.1	0.6	-1.6
Medication: Blood pressure	0.3	0.6	2.2	0.7	1.0	0.7	-1.0	-0.2	0.5	0.0	-0.1	-1.5	0.6
Comparative height size at age 10	0.3	1.6	5.1	-1.3	1.2	0.4	-1.0	-0.5	1.7	-0.6	0.1	-2.3	1.7
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.1	0.4	0.3	0.4	0.1	0.6	0.8	0.4	0.0	-0.0	1.5
Asthma (self-reported)	0.3	0.6	2.9	0.7	0.3	-1.7	-1.1	-0.5	-0.1	0.7	-0.6	0.5	-0.2
Heart disease (siblings)	0.3	0.4	1.8	1.3	0.3	0.5	0.7	-0.2	0.3	0.9	0.1	0.4	0.1
Intelligence (Savage-Jansen 2018)	0.2	0.7	2.7	-1.6	-0.0	0.0	0.1	-0.6	-0.7	-0.2	0.7	1.4	-1.2
Alzheimer’s Disease (in mother)	0.2	0.2	0.9	-0.1	0.1	-0.5	0.5	-0.5	-0.9	0.3	-0.8	-0.2	0.1
Crohns Disease (2017)	0.2	0.5	2.0	-0.5	-0.1	-0.5	0.1	-0.5	0.4	1.4	0.5	0.7	1.1
LDL Cholesterol	0.2	0.3	1.1	1.1	-0.5	-0.0	0.3	0.7	0.7	-0.1	-0.5	-0.0	-0.3
Tanning	0.2	2.8	6.4	-2.1	-1.4	-2.5	-1.1	-0.3	-2.5	-0.7	-2.0	-0.1	-1.6
Medication: Metformin	0.2	0.3	0.9	0.2	-0.4	-0.1	-0.7	-0.3	1.0	0.6	0.1	0.1	0.9
Multivitamins +/- minerals	0.2	0.2	0.9	-0.1	0.6	0.9	-0.1	0.1	0.3	0.3	-0.0	-0.4	0.8
Fluid intelligence score	0.2	0.4	1.4	-1.2	-0.3	-0.4	-0.3	-0.7	-0.7	-0.6	-0.2	-0.4	-0.7
Father’s age at death	0.2	0.3	1.0	-0.3	0.4	0.6	-0.3	-0.7	0.3	-1.0	-0.4	-0.1	-0.7
Happiness	0.2	0.2	0.9	0.9	-0.5	0.0	0.1	-0.0	-0.5	-0.3	-0.2	0.4	-0.3
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.3	-0.3	0.2	-1.2	-1.1	-0.3	-0.9	0.4	-0.5	0.1	-0.4
Depression (self-reported)	0.2	0.3	1.3	0.0	1.1	0.2	-0.2	0.8	0.4	0.5	0.1	0.6	0.0
Birth weight of first child	0.2	0.4	1.3	-1.0	0.3	-0.1	-0.8	0.0	-0.5	-0.5	-0.4	-1.2	-0.3
Headache pain in last month	0.2	0.3	1.0	-0.2	-0.6	-0.3	0.7	-0.5	-1.0	0.6	-0.2	0.9	-0.3
Wheeze or whistling in the chest in last year	0.2	0.4	1.6	-1.3	-0.2	0.1	-0.3	-1.1	0.3	0.6	-0.0	-0.7	-0.0
Family relationship satisfaction	0.2	0.3	1.0	0.3	-0.3	-0.6	-0.6	-0.1	-0.4	-0.1	-0.6	0.4	-1.0
Diabetes diagnosed by doctor	0.2	0.3	1.0	1.0	-0.5	0.2	-0.1	-0.1	0.5	0.8	0.5	0.6	0.7
Hearing aid user	0.2	0.2	1.1	0.2	-0.1	0.1	0.6	-0.6	-0.4	0.1	-0.3	0.5	-1.1
Medication: Atorvastatin	0.2	0.3	0.9	0.7	0.7	0.1	0.1	-0.5	-0.0	-0.0	0.9	-0.8	0.3
Alcohol drinker status: Never	0.2	0.2	1.6	-0.3	-0.1	-0.5	0.5	1.2	0.0	0.0	-0.2	0.1	-0.1
Blood Eosinophil Count	0.1	0.8	4.3	2.1	1.2	-0.1	-0.9	0.6	-0.2	0.7	0.2	0.3	0.6
Blood Platelet Count	0.1	0.6	2.4	1.6	1.2	0.3	-0.3	0.2	0.6	1.0	0.5	0.3	0.6
Height	0.1	1.7	6.1	-0.5	2.5	-0.1	-2.2	1.5	-0.6	-1.6	0.4	-0.8	0.1
Hypothyroidism (self reported)	0.1	0.3	1.7	0.2	0.9	-0.1	-0.5	-1.3	0.1	0.2	0.2	0.4	0.4
Hearing difficulty/problems: Yes	0.1	0.1	0.3	-0.5	-0.5	-0.2	-0.2	0.4	0.5	0.0	-0.2	-0.4	0.4
Qualifications: None of the above	0.1	0.3	0.7	0.0	0.5	0.8	0.4	-0.7	0.6	0.0	0.8	-0.2	-0.2
Diabetes (self-reported)	0.1	0.2	0.6	0.8	-0.7	-0.1	-0.1	-0.5	0.5	0.0	-0.0	0.4	0.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.3	0.9	0.1	0.8	-0.5	0.1	0.4	-1.0	-0.4	-0.0	0.9	-0.6

Hub : Genes

MVB12B

Models

Trait associations