[Hub]/) : Traits : Hair/balding pattern: Pattern 4 :

chr10:76,664,253-80,383,574

Best TWAS P=6.26e-31 · Best GWAS P=1.8e-35 conditioned to 2.61e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C10orf11 0.28 0.05 bslmm 829 0.17 3.3e-20 -4.2 7.7 1.3e-14 -0.32 0.99 0.01 TRUE
2 GTEx Adipose Subcutaneous DLG5 0.39 0.40 lasso 12 0.43 1.9e-38 5.1 5.4 8.5e-08 0.01 0.01 0.99 FALSE
3 GTEx Adipose Subcutaneous RP13-39P12.3 0.31 0.27 lasso 12 0.34 1.1e-28 5.1 5.3 1.3e-07 0.00 0.01 0.99 FALSE
4 GTEx Adipose Visceral Omentum DLG5 0.26 0.23 lasso 8 0.21 5.7e-11 5.1 5.3 9.5e-08 0.00 0.01 0.99 FALSE
5 GTEx Adipose Visceral Omentum RP13-39P12.3 0.18 0.07 lasso 7 0.06 3.3e-04 5.1 5.3 1.1e-07 -0.02 0.01 0.98 FALSE
6 GTEx Adrenal Gland DLG5 0.22 0.14 lasso 6 0.11 8.5e-05 5.1 5.2 2.2e-07 0.05 0.01 0.98 FALSE
7 GTEx Artery Aorta DLG5 0.26 0.19 enet 10 0.22 2.6e-12 4.9 5.2 2.2e-07 0.02 0.01 0.98 FALSE
8 GTEx Artery Aorta RP13-39P12.3 0.14 0.13 enet 9 0.12 2.2e-07 4.9 5.3 1.4e-07 0.02 0.01 0.98 FALSE
9 GTEx Artery Coronary DLG5 0.33 0.25 lasso 4 0.27 1.4e-09 5.0 5.3 1.1e-07 0.02 0.01 0.99 FALSE
10 GTEx Artery Coronary RP13-39P12.3 0.21 0.03 lasso 4 0.09 7.2e-04 5.0 5.1 2.8e-07 0.01 0.03 0.92 FALSE
11 GTEx Artery Tibial DLG5 0.24 0.18 lasso 5 0.18 9.7e-14 5.2 5.2 1.9e-07 0.01 0.01 0.99 FALSE
12 GTEx Artery Tibial RP13-39P12.3 0.14 0.04 lasso 7 0.05 7.3e-05 5.2 5.4 6.3e-08 -0.01 0.02 0.98 FALSE
13 GTEx Brain Caudate basal ganglia C10orf11 0.35 0.27 lasso 4 0.25 9.8e-08 -11.0 11.0 4.6e-28 -0.79 0.23 0.75 FALSE
14 GTEx Brain Cerebellum DLG5 0.36 0.28 lasso 7 0.36 1.6e-11 5.1 5.2 1.8e-07 0.01 0.01 0.98 FALSE
15 GTEx Brain Cortex C10orf11 0.32 0.15 lasso 8 0.21 1.4e-06 -10.9 11.6 6.3e-31 -0.78 0.17 0.81 TRUE
16 GTEx Brain Frontal Cortex BA9 C10orf11 0.33 0.18 enet 11 0.19 9.3e-06 -11.0 11.3 9.7e-30 -0.79 0.27 0.64 FALSE
17 GTEx Breast Mammary Tissue DLG5 0.15 0.09 lasso 7 0.08 6.7e-05 4.9 5.2 2.6e-07 0.02 0.02 0.96 FALSE
18 GTEx Cells Transformed fibroblasts DLG5 0.25 0.18 lasso 11 0.16 2.0e-12 5.1 5.4 7.3e-08 0.01 0.01 0.99 FALSE
19 GTEx Cells Transformed fibroblasts RP13-39P12.3 0.19 0.13 lasso 7 0.15 4.5e-11 5.1 5.7 1.6e-08 0.01 0.01 0.99 FALSE
20 GTEx Colon Sigmoid DLG5 0.23 0.11 lasso 5 0.15 4.6e-06 -3.9 5.2 1.7e-07 -0.01 0.03 0.92 FALSE
21 GTEx Colon Transverse DLG5 0.23 0.17 lasso 8 0.19 1.4e-09 5.0 5.3 1.5e-07 0.02 0.01 0.99 FALSE
22 GTEx Esophagus Gastroesophageal Junction DLG5 0.27 0.03 enet 13 0.06 3.9e-03 4.5 5.7 1.2e-08 0.04 0.02 0.94 FALSE
23 GTEx Esophagus Mucosa DLG5 0.21 0.16 lasso 5 0.18 5.2e-12 5.1 5.3 1.1e-07 0.01 0.01 0.99 FALSE
24 GTEx Esophagus Muscularis DLG5 0.14 0.04 enet 27 0.06 1.9e-04 -3.5 5.8 6.1e-09 0.03 0.06 0.90 TRUE
25 GTEx Heart Atrial Appendage DLG5 0.32 0.23 lasso 4 0.24 3.9e-11 4.9 5.1 2.9e-07 0.01 0.01 0.99 FALSE
26 GTEx Lung DLG5 0.41 0.38 lasso 8 0.37 7.9e-30 5.1 5.2 1.9e-07 0.01 0.01 0.99 FALSE
27 GTEx Muscle Skeletal C10orf11 0.11 0.13 lasso 3 0.12 5.1e-12 -10.9 11.3 8.3e-30 -0.82 0.60 0.40 FALSE
28 GTEx Nerve Tibial DLG5 0.51 0.44 lasso 6 0.50 1.4e-39 5.2 5.3 1.4e-07 0.02 0.01 0.99 FALSE
29 GTEx Nerve Tibial RP13-39P12.3 0.31 0.25 lasso 7 0.36 1.3e-26 5.1 5.2 2.1e-07 0.00 0.01 0.99 FALSE
30 GTEx Ovary DLG5 0.62 0.38 lasso 6 0.40 5.3e-11 5.1 5.2 2.5e-07 0.02 0.01 0.99 FALSE
31 GTEx Pancreas RP13-39P12.3 0.20 0.24 lasso 3 0.23 3.8e-10 5.1 5.1 2.8e-07 0.01 0.01 0.99 FALSE
32 GTEx Pituitary DLG5 0.45 0.36 lasso 11 0.31 1.9e-08 5.1 5.3 1.3e-07 0.01 0.01 0.99 FALSE
33 GTEx Pituitary RP13-39P12.3 0.38 0.22 lasso 11 0.17 3.8e-05 5.1 5.3 9.1e-08 0.01 0.02 0.96 FALSE
34 GTEx Skin Sun Exposed Lower leg DLG5 0.12 0.06 lasso 4 0.06 4.9e-06 5.1 5.3 1.1e-07 0.00 0.01 0.99 FALSE
35 GTEx Spleen DLG5 0.51 0.46 lasso 4 0.44 1.1e-12 5.2 5.2 1.6e-07 0.02 0.01 0.99 FALSE
36 GTEx Spleen RP13-39P12.3 0.38 0.34 lasso 2 0.35 8.8e-10 5.2 5.4 5.8e-08 0.00 0.01 0.99 FALSE
37 GTEx Stomach DLG5 0.20 0.12 lasso 7 0.08 1.3e-04 5.2 5.2 2.3e-07 0.02 0.01 0.99 FALSE
38 GTEx Stomach RP13-39P12.3 0.17 0.02 lasso 5 0.02 2.5e-02 -3.9 5.1 3.0e-07 -0.03 0.02 0.84 FALSE
39 GTEx Thyroid RP13-39P12.3 0.28 0.30 lasso 8 0.29 3.3e-22 5.1 5.2 2.1e-07 0.01 0.01 0.99 FALSE
40 METSIM Adipose DLG5 0.18 0.19 lasso 11 0.22 2.2e-32 5.1 5.4 7.7e-08 -0.01 0.01 0.99 FALSE
41 ROSMAP Brain Pre-frontal Cortex C10orf11 0.20 0.23 lasso 4 0.23 1.1e-29 -10.9 11.1 1.8e-28 -0.78 1.00 0.00 FALSE
42 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DLG5 0.12 0.01 blup 116 0.03 1.2e-02 5.0 5.1 2.7e-07 -0.02 0.02 0.62 FALSE