[Hub]/) : Traits : Hair/balding pattern: Pattern 4 :

chr10:125,455,780-127,372,751

Best TWAS P=2.11e-19 · Best GWAS P=3.69e-34 conditioned to 1.42e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM53B 0.05 0.00 blup 626 0.01 1.9e-02 6.64 7.2 6.6e-13 0.55 0.06 0.68 FALSE
2 GTEx Brain Caudate basal ganglia METTL10 0.33 0.16 lasso 3 0.18 7.6e-06 8.61 -7.7 1.1e-14 -0.78 0.16 0.70 FALSE
3 GTEx Brain Cerebellum LHPP 0.41 0.03 enet 34 0.11 4.1e-04 7.05 6.1 1.3e-09 0.37 0.21 0.06 FALSE
4 GTEx Brain Frontal Cortex BA9 METTL10 0.24 0.00 lasso 3 0.02 9.3e-02 -6.83 -8.9 5.6e-19 -0.74 0.06 0.44 FALSE
5 GTEx Breast Mammary Tissue METTL10 0.13 0.08 enet 19 0.13 4.8e-07 -6.57 -6.8 1.2e-11 -0.55 0.78 0.21 FALSE
6 GTEx Breast Mammary Tissue (Female) METTL10 0.27 0.00 lasso 5 0.04 1.8e-02 -6.57 -7.3 2.6e-13 -0.47 0.08 0.62 FALSE
7 GTEx Cells Transformed fibroblasts FAM53B 0.22 0.08 lasso 8 0.07 3.7e-06 -6.61 6.3 3.4e-10 0.41 0.90 0.02 FALSE
8 GTEx Colon Transverse METTL10 0.18 0.01 enet 17 0.07 2.2e-04 12.08 -9.0 2.1e-19 -0.72 0.02 0.90 TRUE
9 GTEx Nerve Tibial LHPP 0.18 0.05 lasso 5 0.09 4.1e-07 4.61 5.8 5.2e-09 0.48 0.87 0.05 FALSE
10 GTEx Thyroid METTL10 0.19 0.09 enet 33 0.10 3.0e-08 -3.76 -6.2 7.3e-10 -0.54 0.78 0.22 FALSE
11 NTR Blood ZRANB1 0.04 0.01 bslmm 567 0.02 3.8e-06 -2.73 5.6 2.0e-08 0.33 0.96 0.01 FALSE
12 ROSMAP Brain Pre-frontal Cortex LHPP 0.22 0.07 bslmm 582 0.16 1.8e-19 3.87 5.5 4.6e-08 0.48 1.00 0.00 FALSE
13 The Cancer Genome Atlas Bladder Urothelial Carcinoma LHPP 0.08 0.00 blup 171 0.03 3.0e-03 0.16 5.2 2.4e-07 0.41 0.14 0.15 FALSE
14 The Cancer Genome Atlas Bladder Urothelial Carcinoma METTL10 0.09 0.08 blup 43 0.11 1.2e-09 -3.63 -6.4 1.5e-10 -0.60 1.00 0.00 FALSE
15 The Cancer Genome Atlas Brain Lower Grade Glioma LHPP 0.09 0.00 blup 170 0.03 9.7e-05 -1.38 5.2 1.8e-07 0.36 0.08 0.04 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma METTL10 0.13 0.16 blup 43 0.18 1.8e-20 -3.63 -6.8 9.7e-12 -0.61 1.00 0.00 FALSE
17 The Cancer Genome Atlas Pancreatic Adenocarcinoma METTL10 0.18 0.13 enet 12 0.11 2.4e-05 -3.85 -5.2 1.7e-07 -0.52 0.30 0.58 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma LHPP 0.09 0.00 blup 172 0.03 1.4e-04 -3.05 5.8 6.9e-09 0.37 0.15 0.05 FALSE
19 The Cancer Genome Atlas Testicular Germ Cell Tumors LHPP 0.45 0.01 enet 38 0.05 5.5e-03 -3.23 5.2 1.6e-07 0.26 0.03 0.10 TRUE
20 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma METTL10 0.13 0.08 blup 43 0.12 2.4e-04 -3.76 -6.2 6.0e-10 -0.55 0.18 0.16 FALSE