Best TWAS P=8.89e-28 · Best GWAS P=2.06e-33 conditioned to 2.48e-25
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | GDAP2 | 0.06 | 0.01 | blup | 407 | 0.04 | 2.5e-05 | 6.4 | -5.9 | 2.9e-09 | -0.27 | 0.56 | 0.03 | TRUE |
| 2 | GTEx | Testis | WARS2 | 0.25 | 0.17 | lasso | 3 | 0.17 | 4.3e-08 | -9.8 | -10.9 | 8.9e-28 | -0.04 | 0.00 | 1.00 | TRUE |
| 3 | GTEx | Testis | RP11-418J17.1 | 0.17 | 0.00 | enet | 30 | 0.00 | 3.9e-01 | 8.9 | 5.8 | 6.6e-09 | 0.00 | 0.09 | 0.06 | FALSE |
| 4 | GTEx | Thyroid | GDAP2 | 0.09 | 0.04 | lasso | 6 | 0.02 | 2.0e-02 | 5.9 | 5.2 | 2.1e-07 | 0.16 | 0.33 | 0.02 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | GDAP2 | 0.03 | 0.01 | blup | 37 | 0.02 | 2.5e-03 | 5.2 | 5.2 | 1.6e-07 | 0.13 | 0.03 | 0.62 | FALSE |