Best TWAS P=4.52e-08 · Best GWAS P=1.36e-22 conditioned to 7.37e-21
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | RBL2 | 0.35 | 0.27 | enet | 22 | 0.25 | 2.3e-09 | -4.9 | 5.2 | 2.1e-07 | 0.04 | 1.00 | 0.00 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | RBL2 | 0.13 | 0.05 | enet | 9 | 0.02 | 8.9e-03 | -5.0 | 5.4 | 7.7e-08 | 0.06 | 0.55 | 0.02 | FALSE |
| 3 | GTEx | Colon Transverse | RBL2 | 0.59 | 0.44 | enet | 13 | 0.52 | 4.4e-28 | -4.9 | 5.1 | 2.7e-07 | 0.05 | 1.00 | 0.00 | FALSE |
| 4 | GTEx | Esophagus Mucosa | RBL2 | 0.36 | 0.36 | enet | 37 | 0.37 | 2.9e-26 | -4.9 | 5.3 | 9.7e-08 | 0.00 | 1.00 | 0.00 | FALSE |
| 5 | GTEx | Heart Atrial Appendage | RBL2 | 0.28 | 0.14 | enet | 25 | 0.23 | 8.6e-11 | -4.9 | 5.3 | 1.0e-07 | 0.03 | 1.00 | 0.00 | FALSE |
| 6 | GTEx | Pancreas | RBL2 | 0.36 | 0.36 | enet | 26 | 0.36 | 5.9e-16 | -4.9 | 5.5 | 4.5e-08 | 0.08 | 1.00 | 0.00 | TRUE |
| 7 | NTR | Blood | RBL2 | 0.09 | 0.11 | bslmm | 419 | 0.11 | 1.1e-33 | -4.9 | 5.3 | 1.2e-07 | 0.06 | 1.00 | 0.00 | FALSE |
| 8 | YFS | Blood | RBL2 | 0.18 | 0.26 | bslmm | 381 | 0.27 | 6.9e-90 | -4.9 | 5.4 | 8.2e-08 | 0.09 | 1.00 | 0.00 | FALSE |