Best TWAS P=3.26e-09 · Best GWAS P=1.1e-08 conditioned to 0.00985
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | UBA7 | 0.06 | 0.02 | enet | 12 | 0.01 | 5.3e-02 | 4.3 | -5.2 | 2.3e-07 | 0.69 | 0.09 | 0.77 | FALSE |
| 2 | GTEx | Brain Cortex | RBM6 | 0.21 | 0.25 | lasso | 4 | 0.29 | 8.8e-09 | -4.9 | -5.7 | 1.0e-08 | 0.84 | 0.05 | 0.94 | FALSE |
| 3 | GTEx | Brain Nucleus accumbens basal ganglia | RBM6 | 0.20 | 0.19 | enet | 29 | 0.22 | 2.0e-06 | -4.9 | -5.6 | 2.1e-08 | 0.69 | 0.11 | 0.87 | FALSE |
| 4 | GTEx | Lung | TCTA | 0.09 | 0.01 | enet | 10 | 0.03 | 3.3e-03 | 2.9 | 5.5 | 3.0e-08 | -0.26 | 0.05 | 0.10 | TRUE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | RBM6 | 0.21 | 0.32 | enet | 31 | 0.34 | 1.5e-44 | -4.9 | -5.3 | 1.5e-07 | 0.60 | 0.15 | 0.84 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RBM6 | 0.03 | 0.04 | blup | 79 | 0.05 | 9.5e-10 | -4.8 | -5.3 | 1.3e-07 | 0.61 | 0.12 | 0.87 | FALSE |
| 7 | The Cancer Genome Atlas | Colon Adenocarcinoma | UBA7 | 0.11 | 0.06 | enet | 5 | 0.05 | 7.6e-04 | 4.1 | -5.2 | 1.7e-07 | 0.60 | 0.02 | 0.97 | FALSE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MST1R | 0.08 | 0.07 | enet | 10 | 0.09 | 2.6e-10 | 4.3 | 5.2 | 2.2e-07 | -0.50 | 0.02 | 0.97 | FALSE |
| 9 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | RBM6 | 0.16 | 0.12 | blup | 79 | 0.09 | 4.4e-04 | -4.8 | -5.9 | 3.3e-09 | 0.68 | 0.10 | 0.86 | TRUE |