Hub : Genes

UBA7

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.0610	0.0320	3.2e-03	0.024	NA	0.014	NA	-0.003	1.8e-02	NA	5.3e-02	NA	5.4e-01
2	GTEx	Artery Tibial	0.0425	0.0292	9.9e-03	0.032	NA	0.005	NA	0.021	1.5e-03	NA	1.2e-01	NA	7.8e-03
3	GTEx	Cells Transformed fibroblasts	0.0690	0.0380	6.1e-04	0.064	NA	0.038	NA	0.007	1.4e-05	NA	7.5e-04	NA	8.7e-02
4	GTEx	Colon Transverse	0.2790	0.0730	6.8e-13	0.305	NA	0.283	NA	0.299	5.3e-15	NA	7.1e-14	NA	1.1e-14
5	GTEx	Esophagus Mucosa	0.0430	0.0210	8.9e-04	0.073	NA	0.046	NA	-0.004	1.3e-05	NA	4.5e-04	NA	9.8e-01
6	GTEx	Skin Not Sun Exposed Suprapubic	0.0660	0.0310	2.7e-04	0.034	NA	0.057	NA	0.061	5.8e-03	NA	4.7e-04	NA	2.9e-04
7	GTEx	Skin Sun Exposed Lower leg	0.0400	0.0250	5.8e-03	0.009	NA	-0.001	NA	0.000	5.8e-02	NA	4.4e-01	NA	2.9e-01
8	GTEx	Spleen	0.1900	0.0800	2.0e-04	0.135	NA	0.110	NA	0.111	2.5e-04	NA	9.5e-04	NA	8.8e-04
9	GTEx	Thyroid	0.0450	0.0240	5.1e-03	0.008	NA	0.021	NA	0.008	7.2e-02	NA	9.2e-03	NA	7.2e-02
10	GTEx	Whole Blood	0.0310	0.0180	3.7e-03	0.039	NA	0.005	NA	0.015	1.5e-04	NA	1.1e-01	NA	1.5e-02
11	NTR	Blood	0.0185	0.0083	6.3e-08	0.030	0.026	0.024	0.026	0.028	4.9e-10	5.3e-09	2.0e-08	4.8e-09	1.6e-09
12	YFS	Blood	0.1630	0.0429	0.0e+00	0.235	0.224	0.229	0.229	0.234	1.3e-75	1.1e-71	2.2e-73	1.9e-73	4.0e-75
13	TCGA	Breast Invasive Carcinoma	0.0134	0.0084	2.9e-04	0.014	0.005	0.014	NA	-0.001	5.6e-04	2.7e-02	6.6e-04	NA	8.4e-01
14	TCGA	Colon Adenocarcinoma	0.1100	0.0660	2.5e-06	0.063	0.022	0.049	NA	0.016	1.7e-04	1.9e-02	7.6e-04	NA	3.8e-02
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.0189	0.0131	4.5e-03	0.021	0.018	0.009	NA	0.013	1.7e-03	3.8e-03	3.0e-02	NA	1.1e-02
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0790	0.0400	1.7e-09	0.092	0.086	0.084	NA	0.089	1.4e-10	6.4e-10	1.1e-09	NA	3.4e-10
17	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1340	0.0680	2.3e-08	0.162	0.139	0.144	NA	0.146	1.5e-09	2.4e-08	1.3e-08	NA	1.1e-08
18	TCGA	Lung Adenocarcinoma	0.0334	0.0198	3.4e-05	0.041	0.007	0.020	NA	-0.001	1.2e-05	4.0e-02	1.8e-03	NA	3.8e-01
19	TCGA	Lung Squamous Cell Carcinoma	0.0170	0.0115	3.3e-03	0.014	0.016	0.016	NA	0.010	9.5e-03	5.3e-03	5.9e-03	NA	2.3e-02
20	TCGA	Pancreatic Adenocarcinoma	0.1110	0.0800	6.4e-05	0.143	0.089	0.109	NA	-0.002	1.4e-06	1.5e-04	2.7e-05	NA	4.1e-01
21	TCGA	Prostate Adenocarcinoma	0.0494	0.0298	3.7e-06	0.043	0.036	0.045	NA	0.038	2.6e-05	1.0e-04	1.6e-05	NA	7.6e-05
22	TCGA	Stomach Adenocarcinoma	0.0400	0.0260	1.1e-03	0.048	0.033	0.034	NA	0.037	2.0e-04	1.9e-03	1.7e-03	NA	1.0e-03
23	TCGA	Thyroid Carcinoma	0.0300	0.0200	1.6e-03	0.006	0.024	0.011	NA	0.015	7.6e-02	2.0e-03	2.9e-02	NA	1.1e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Bipolar Disorder (2018)	1.8	2.8	7.1	-1.3	-1.6	-1.3	-1.5	-1.3	-2.7	-2.5	-1.5	-2.3	-1.3	-1.4	-1.5	-1.5	-1.1	-1.8	-1.4	-1.4	-1.4	-1.1	-1.5	-1.9	-1.3	-2.4
Bipolar Disorder or Schizophrenia	0.2	0.4	1.0	0.3	-0.5	0.7	0.4	0.7	-0.9	-0.7	0.7	-1.0	0.6	0.8	0.7	0.0	0.4	0.4	0.7	0.8	0.6	0.9	0.6	0.1	0.8	-0.3
Depressed Affect (Nagel 2018)	13.3	28.1	34.9	-4.3	-4.9	-5.3	-5.4	-5.5	-5.7	-5.8	-5.4	-4.6	-5.3	-5.4	-5.3	-5.2	-4.4	-5.7	-5.4	-5.2	-5.4	-5.0	-5.4	-5.6	-5.3	-5.9
Depression (Nagel 2018)	1.9	2.9	4.3	-1.7	-1.9	-1.5	-1.8	-1.6	-2.0	-1.9	-2.1	-1.0	-1.3	-1.6	-1.6	-1.8	-1.4	-1.9	-1.6	-1.8	-1.7	-1.7	-1.7	-1.8	-1.5	-2.0
Intelligence (Savage-Jansen 2018)	34.4	105.7	125.4	9.3	9.9	10.9	10.6	11.1	8.5	9.5	10.3	6.9	11.2	11.0	10.7	9.7	9.2	11.0	10.9	10.9	10.7	10.5	10.6	10.7	10.9	10.2
Neuroticism (Nagel 2018)	4.9	11.5	14.5	-3.2	-3.3	-3.3	-3.6	-3.4	-3.8	-3.6	-3.7	-3.1	-2.8	-3.4	-3.4	-3.4	-2.9	-3.5	-3.4	-3.2	-3.4	-3.2	-3.4	-3.5	-3.4	-3.8
Schizophrenia (2018)	1.5	3.0	4.6	1.5	0.6	2.0	1.8	2.0	1.0	1.1	2.1	0.6	1.8	2.1	2.0	1.2	1.4	2.0	2.0	2.1	1.9	2.0	2.0	1.7	2.0	1.5
Schizophrenia vs Biploar Disorder	5.2	6.9	9.8	3.0	3.1	2.4	2.5	2.7	2.6	2.4	2.7	2.6	2.7	2.8	2.5	2.2	2.0	3.0	2.5	2.4	2.4	2.6	2.5	2.7	2.4	3.1
Worry (Nagel 2018)	1.2	2.5	5.6	-2.4	-2.1	-1.6	-1.8	-1.7	-0.9	-1.2	-2.1	-0.7	-1.0	-1.8	-1.6	-1.7	-1.5	-1.4	-1.6	-1.5	-1.7	-1.8	-1.7	-1.3	-1.6	-1.2
Alzheimer’s Disease (in mother)	1.8	2.1	3.5	-1.9	-1.6	-1.5	-1.6	-1.4	-0.6	-1.4	-1.6	-0.8	-1.5	-1.4	-1.5	-1.4	-1.5	-1.4	-1.4	-1.5	-1.5	-1.7	-1.6	-1.2	-1.4	-1.2
Alzheimer’s Disease (in father)	0.3	0.3	0.7	-0.6	-0.8	-0.7	-0.5	-0.7	0.0	-0.1	-0.7	0.2	-0.8	-0.8	-0.6	-0.5	-0.6	-0.4	-0.8	-0.4	-0.6	-0.8	-0.7	-0.4	-0.8	-0.2
Alzheimer’s Disease (including proxy)	1.5	2.1	6.5	-2.0	-2.5	-1.5	-1.3	-1.6	-0.6	-1.3	-1.6	-0.6	-1.8	-1.7	-1.4	-1.0	-1.1	-1.2	-1.5	-1.4	-1.4	-1.5	-1.5	-1.1	-1.6	-0.9
Crohns Disease (2017)	15.9	34.8	50.1	4.0	4.0	6.7	6.6	6.4	3.1	4.3	6.9	-0.4	6.2	6.5	6.7	5.1	5.9	6.3	6.5	7.0	6.6	7.1	6.8	5.8	6.6	5.4
Irritable Bowel Disease (IBD)	20.2	48.2	66.7	4.5	5.2	7.6	7.6	7.4	4.9	5.7	7.8	0.9	7.3	7.5	7.7	5.9	6.3	7.9	7.5	8.2	7.7	8.0	7.8	7.0	7.5	7.2
Ulcerative Colitis (UC)	16.5	30.9	43.8	3.6	4.4	5.8	5.9	5.8	5.1	5.3	5.9	2.4	5.7	5.9	5.9	4.8	4.7	6.6	5.8	6.4	5.9	6.0	6.0	5.9	5.8	6.4
Major Depression (MDD)	7.6	9.2	15.2	-2.4	-2.8	-2.9	-3.0	-3.0	-3.9	-3.8	-2.6	-3.7	-3.0	-2.9	-2.8	-2.9	-2.3	-3.2	-2.9	-2.7	-2.9	-2.5	-2.7	-3.6	-2.8	-3.5
Reaction Time	4.5	8.5	12.5	3.1	2.5	3.3	3.2	3.2	0.9	1.6	3.3	0.5	3.3	3.2	3.3	2.9	3.3	2.7	3.1	3.2	3.3	3.5	3.3	2.6	3.2	2.1
Verbal and Numeric Reasoning (VNR)	28.0	67.2	76.9	7.5	7.7	8.6	8.6	8.8	7.1	7.7	8.1	5.9	8.6	8.6	8.5	8.1	7.6	8.6	8.6	8.6	8.6	8.3	8.4	8.6	8.6	8.1
Breast Cancer	5.8	14.1	17.5	2.6	2.5	4.1	4.0	3.9	3.3	4.0	3.9	2.0	3.7	3.9	4.0	3.6	3.3	4.0	4.2	4.0	4.1	3.8	4.1	4.0	4.2	4.0
Ovarian Cancer	0.1	0.1	0.4	0.7	0.3	0.3	0.3	0.3	-0.3	-0.1	0.4	-0.0	0.4	0.3	0.2	0.3	0.3	0.1	0.3	0.2	0.3	0.4	0.3	0.2	0.4	0.0
Prostate Cancer	10.7	15.0	19.7	-2.2	-1.9	-4.1	-4.1	-4.0	-4.3	-4.2	-4.1	-2.9	-3.5	-4.0	-4.1	-3.9	-3.6	-4.1	-4.1	-4.0	-4.1	-3.6	-4.1	-4.4	-4.1	-4.4
Age at First Birth	38.7	56.3	68.7	7.4	7.3	7.7	7.6	8.0	6.5	7.1	7.3	6.6	8.3	7.9	7.5	7.6	7.4	7.6	7.8	7.0	7.5	7.6	7.5	7.7	7.8	7.6
Bipolar Disorder (2011)	0.6	0.6	1.2	1.0	0.5	0.8	0.9	0.9	-0.5	-0.2	0.9	-0.4	0.7	0.9	0.9	0.5	0.9	0.7	0.7	1.1	0.9	1.0	0.8	0.3	0.8	-0.0
Body Mass Index (BMI) (2010)	4.6	6.4	10.5	-3.2	-3.2	-2.4	-2.4	-2.7	-2.0	-2.2	-2.2	-2.8	-2.9	-2.7	-2.4	-2.5	-2.3	-2.5	-2.4	-2.3	-2.3	-2.6	-2.4	-2.4	-2.4	-2.4
Coronary Artery Disease (CAD)	8.3	9.9	11.6	-3.4	-3.0	-3.2	-3.2	-3.4	-2.5	-2.9	-2.9	-2.9	-3.2	-3.4	-3.1	-3.1	-3.1	-3.3	-3.2	-3.3	-3.2	-3.3	-3.1	-3.2	-3.2	-3.0
Crohns Disease (2012)	16.4	26.4	37.6	4.5	4.6	5.7	5.5	5.5	2.8	3.3	5.7	0.7	5.5	5.6	5.7	4.6	5.2	5.5	5.6	5.9	5.6	6.1	5.7	5.1	5.7	4.7
Mean Putamen Volume	0.9	1.0	1.9	1.0	1.1	1.1	1.0	1.0	0.5	1.2	0.8	1.4	1.4	1.0	1.1	1.1	1.1	0.8	1.0	1.0	1.0	0.9	1.0	0.9	1.0	0.6
Fasting Glucose	2.5	3.0	5.6	-0.6	-0.9	-2.1	-2.2	-2.0	-0.7	-0.8	-1.8	0.4	-2.0	-2.0	-1.8	-1.6	-1.8	-1.8	-2.1	-2.4	-2.0	-1.9	-1.8	-1.8	-2.2	-1.4
HbA1C	0.5	0.5	3.1	-0.0	1.8	-0.1	0.2	0.4	0.9	0.2	-1.0	1.0	0.6	0.3	-0.8	-0.3	-1.0	0.7	0.3	0.6	-0.2	-0.3	-0.9	0.8	0.3	1.0
HDL Cholesterol	3.6	5.9	17.7	4.2	3.8	2.3	2.3	2.6	0.2	1.2	2.6	1.5	2.6	2.7	2.2	2.4	3.0	2.0	2.2	2.1	2.3	3.0	2.4	1.7	2.3	1.5
LDL Cholesterol	0.1	0.1	0.5	0.2	-0.1	0.1	0.1	0.2	0.7	0.5	0.2	0.4	-0.2	0.2	0.2	0.2	-0.1	0.3	0.2	0.1	0.1	0.1	0.0	0.3	0.2	0.5
Lupus	0.4	0.6	4.5	-1.4	-1.6	-0.1	-0.1	-0.5	-1.0	-0.7	0.0	-2.1	-0.8	-0.5	-0.0	-0.5	-0.4	-0.7	-0.2	-0.0	-0.1	-0.4	-0.1	-0.5	-0.1	-1.2
Neuroticism (2016)	4.0	5.8	7.7	-1.6	-2.0	-2.5	-2.5	-2.5	-2.6	-2.5	-2.6	-1.8	-2.1	-2.5	-2.5	-2.5	-2.2	-2.6	-2.6	-2.5	-2.5	-2.2	-2.5	-2.7	-2.5	-2.8
Primary Biliary Cirrhosis	2.8	4.0	7.5	2.4	2.7	2.0	2.1	2.1	1.6	1.5	2.0	2.1	2.2	2.1	2.0	1.9	1.8	1.9	2.0	1.9	2.0	1.9	1.9	2.0	2.0	1.7
Rheumatoid Arthritis	0.1	0.1	0.3	0.5	0.5	0.3	0.3	0.3	-0.5	0.0	0.5	-0.1	0.5	0.3	0.4	0.3	0.5	0.1	0.3	0.4	0.3	0.4	0.4	0.1	0.3	-0.2
Schizophrenia (2014)	0.9	2.0	3.4	1.4	0.6	1.6	1.5	1.8	0.5	0.5	1.7	0.2	1.5	1.8	1.6	1.0	1.3	1.6	1.6	1.8	1.6	1.7	1.6	1.2	1.7	1.1
Triglycerides	0.2	0.4	1.9	-0.4	0.2	-0.3	-0.4	-0.2	1.4	0.9	-0.6	1.4	-0.2	-0.3	-0.3	-0.7	-1.2	0.3	-0.2	-0.3	-0.3	-0.7	-0.3	0.4	-0.3	0.6
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.0	-1.0	-0.2	-0.9	-1.0	-0.9	-0.0	-0.5	-1.1	-0.4	-0.6	-0.8	-1.1	-1.3	-1.4	-0.7	-0.7	-1.0	-1.0	-1.2	-1.0	-0.7	-0.8	-0.5
Ulcerative Colitis	15.1	21.9	29.4	3.1	3.9	5.0	5.1	4.9	3.7	4.2	5.2	1.2	4.8	5.0	5.0	4.1	4.2	5.4	4.9	5.4	5.1	5.2	5.2	4.8	4.9	5.1
Blood Eosinophil Count	3.2	24.6	61.3	-7.8	-5.6	-4.9	-5.1	-5.2	-1.6	-3.5	-5.3	-3.1	-5.1	-5.3	-4.8	-5.1	-5.8	-4.7	-4.6	-5.1	-4.9	-5.9	-5.0	-4.0	-4.8	-3.8
Blood Platelet Count	0.1	0.8	6.6	-0.9	-0.4	0.9	0.9	0.4	-0.6	-0.3	1.2	-2.6	-0.2	0.5	0.8	0.3	0.8	0.3	0.7	1.1	0.9	0.6	0.8	0.4	0.8	-0.0
Blood Red Count	2.0	19.8	43.0	-4.7	-1.9	-5.1	-5.1	-4.7	1.3	-0.8	-5.9	2.2	-3.8	-4.8	-5.0	-5.3	-6.6	-3.0	-4.7	-4.6	-5.1	-6.1	-5.3	-2.9	-5.0	-1.5
Blood White Count	8.7	64.7	74.6	-8.4	-7.1	-8.3	-8.2	-8.6	-6.2	-7.9	-8.0	-7.1	-8.4	-8.6	-8.2	-8.3	-7.9	-8.3	-8.3	-8.1	-8.2	-8.3	-8.1	-8.1	-8.3	-7.7
Heel T-Score	4.6	36.9	85.9	-9.3	-8.5	-6.4	-6.3	-6.8	1.4	-1.7	-6.7	-1.3	-7.0	-6.9	-6.3	-5.7	-7.2	-4.7	-5.9	-6.4	-6.3	-7.4	-6.3	-3.9	-6.3	-2.0
BMI	25.4	147.4	185.0	-13.0	-12.8	-12.2	-12.1	-13.1	-10.2	-10.6	-11.5	-11.7	-13.6	-12.9	-12.0	-12.1	-11.5	-12.6	-12.3	-11.8	-12.1	-12.3	-12.0	-12.2	-12.2	-11.9
Height	0.1	1.8	4.2	0.3	1.6	1.2	1.4	1.4	1.5	0.8	0.8	1.7	1.8	1.2	1.3	2.0	2.1	1.1	1.2	1.2	1.3	1.1	1.2	1.3	1.2	1.2
Waist Hip Ratio (WHR)	0.5	2.1	7.8	-2.8	-0.7	-1.2	-1.3	-0.9	2.2	0.3	-2.0	1.8	-0.3	-1.0	-1.3	-1.7	-2.6	-0.0	-0.9	-0.9	-1.2	-2.0	-1.5	-0.1	-1.1	0.6
Systolic Blood Pressure	3.8	19.2	33.6	-2.9	-1.6	-4.9	-5.0	-4.5	-2.8	-3.7	-5.0	-1.7	-4.3	-4.4	-5.0	-5.5	-5.8	-3.8	-4.8	-4.4	-5.0	-4.9	-4.9	-4.4	-4.8	-3.7
Smoking Status	4.4	10.5	27.1	-1.9	-2.7	-2.8	-2.8	-2.9	-5.2	-4.2	-2.4	-4.5	-3.4	-2.8	-2.9	-2.9	-2.0	-3.8	-2.9	-2.8	-2.8	-2.4	-2.8	-3.8	-2.8	-4.5
Allergy or Eczema	0.3	0.8	2.8	0.4	-0.3	0.9	0.9	0.8	0.2	0.7	0.9	0.5	0.7	0.9	0.9	1.7	1.6	0.5	0.8	0.7	0.9	1.1	0.8	0.7	0.9	0.4
Cardiovascular Disease	2.4	8.1	12.2	-2.6	-1.9	-3.1	-3.1	-3.0	-1.7	-1.9	-3.2	-1.8	-3.0	-3.0	-3.1	-3.5	-3.5	-2.5	-3.0	-2.6	-3.1	-3.2	-3.1	-2.9	-3.1	-2.4
Hypothyroidism (self reported)	0.7	1.7	3.0	-1.0	-1.0	-1.3	-1.1	-1.3	-1.7	-1.6	-1.0	-1.7	-1.2	-1.4	-1.2	-1.5	-1.3	-1.2	-1.4	-0.8	-1.2	-1.0	-1.1	-1.5	-1.4	-1.5
Respiratory disease	6.7	14.9	23.4	-4.7	-4.6	-3.6	-3.5	-3.8	-4.0	-3.9	-3.6	-4.8	-3.9	-3.9	-3.6	-3.7	-3.2	-4.0	-3.6	-3.3	-3.5	-3.4	-3.6	-4.1	-3.6	-4.3
Type 2 Diabetes (T2D) (2018)	11.7	22.0	35.2	-5.8	-4.5	-4.8	-4.7	-5.0	-2.4	-3.6	-4.9	-3.6	-5.0	-5.0	-4.8	-5.6	-5.9	-4.1	-4.8	-4.2	-4.8	-5.3	-4.8	-4.3	-4.8	-3.7
Lung FEV1/FVC ratio	2.9	14.5	37.5	1.2	1.6	3.8	4.0	3.6	6.1	4.8	3.1	4.9	3.6	3.4	3.9	3.2	2.0	4.0	4.0	3.9	3.9	2.2	3.5	4.8	3.8	4.5
Lung FVC	5.5	28.0	37.8	3.4	2.9	5.5	5.5	5.3	6.1	6.0	5.4	4.0	4.6	5.3	5.6	5.4	4.6	5.9	5.6	5.6	5.5	4.9	5.5	6.1	5.5	6.0
Neuroticism	7.0	16.9	19.5	-3.8	-3.9	-4.1	-4.3	-4.2	-4.3	-4.3	-4.3	-3.7	-3.8	-4.2	-4.1	-4.3	-3.7	-4.2	-4.2	-3.9	-4.2	-3.9	-4.2	-4.3	-4.1	-4.4
Chronotype (morning person)	3.6	8.4	18.4	2.6	3.0	2.7	2.7	2.7	3.8	3.2	3.0	1.4	2.2	2.8	2.7	2.6	2.1	3.6	2.8	2.7	2.7	3.0	2.9	3.2	2.7	4.3
Hair Pigment	0.0	0.3	1.8	-0.9	-0.9	0.3	0.4	0.2	-0.9	-0.3	0.4	-1.3	-0.1	0.2	0.3	0.0	0.2	-0.4	0.4	0.2	0.4	-0.0	0.2	-0.5	0.5	-0.6
Tanning	0.4	4.5	6.0	-2.2	-1.9	-2.3	-2.0	-2.4	-1.2	-1.4	-2.1	-1.2	-2.4	-2.4	-2.3	-2.2	-2.3	-2.2	-2.3	-2.3	-2.2	-2.4	-2.3	-2.1	-2.3	-1.8
Hand grip strength (left)	1.3	3.4	5.8	-1.2	-1.2	-2.1	-2.2	-2.1	-1.0	-1.5	-2.2	-0.2	-2.3	-2.1	-2.1	-1.1	-1.0	-2.1	-2.1	-2.4	-2.1	-2.0	-2.1	-1.8	-2.1	-1.6
Number of treatments/medications taken	21.0	37.8	42.3	-6.1	-5.6	-6.2	-6.2	-6.4	-5.6	-5.9	-6.3	-5.5	-6.2	-6.4	-6.2	-6.5	-6.1	-6.4	-6.2	-5.9	-6.2	-6.2	-6.1	-6.5	-6.2	-6.4
Average weekly spirits intake	4.1	5.1	8.7	-1.3	-1.8	-2.5	-2.4	-2.5	-1.9	-2.1	-2.5	-0.0	-2.1	-2.5	-2.5	-1.7	-1.6	-2.9	-2.5	-3.0	-2.5	-2.4	-2.6	-2.4	-2.5	-2.4
Sensitivity / hurt feelings	0.2	0.3	1.6	-1.2	-0.7	-0.3	-0.3	-0.3	-0.6	-0.3	-0.5	-1.3	-0.0	-0.4	-0.3	-0.9	-0.7	-0.3	-0.3	0.1	-0.3	-0.5	-0.3	-0.5	-0.3	-0.6
Frequency of depressed mood in last 2 weeks	2.1	2.9	6.9	-2.0	-2.6	-1.5	-1.7	-1.6	-1.9	-2.0	-1.7	-1.5	-1.3	-1.7	-1.5	-1.5	-1.1	-2.0	-1.6	-1.6	-1.6	-1.6	-1.6	-1.8	-1.5	-2.1
Hearing difficulty/problems: Yes	0.1	0.2	2.3	-0.3	-0.4	0.0	-0.0	-0.1	-0.8	-0.4	0.2	-1.5	-0.0	-0.1	-0.0	-0.3	-0.2	-0.1	-0.0	0.0	0.0	0.2	0.2	-0.3	0.0	-0.2
Relative age of first facial hair	2.7	5.6	21.5	-2.7	-2.9	-1.6	-1.6	-1.9	-4.1	-3.4	-1.3	-4.6	-1.9	-1.9	-1.5	-1.8	-1.1	-2.6	-1.8	-1.5	-1.6	-1.4	-1.5	-2.6	-1.6	-3.5
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	2.4	1.2	1.0	1.1	1.3	1.1	-0.7	0.0	1.3	-0.7	1.2	1.1	1.2	1.0	1.4	0.9	1.0	1.5	1.2	1.5	1.2	0.6	1.1	0.1
Ever used hormone-replacement therapy (HRT)	0.9	1.1	5.9	-1.8	-2.1	-0.5	-0.4	-0.9	-1.4	-1.1	-0.3	-2.4	-1.1	-0.9	-0.4	-0.5	-0.3	-1.1	-0.6	-0.4	-0.4	-0.6	-0.5	-1.0	-0.5	-1.4
Ever had hysterectomy (womb removed)	2.6	3.0	10.3	-2.5	-3.2	-1.5	-1.6	-1.7	-1.2	-1.1	-1.6	-1.1	-1.9	-1.7	-1.5	-1.2	-1.2	-2.1	-1.5	-1.7	-1.5	-1.9	-1.6	-1.5	-1.5	-2.0
Systolic blood pressure, automated reading	5.1	14.8	21.5	-2.4	-1.7	-4.0	-4.1	-3.9	-3.7	-4.0	-3.8	-3.4	-3.9	-3.8	-4.2	-4.6	-4.6	-3.6	-4.1	-3.7	-4.1	-3.8	-4.1	-4.1	-4.0	-3.9
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.9	-1.7	-1.1	-1.0	-1.0	-1.1	-0.1	-0.6	-1.2	-0.9	-0.7	-1.1	-1.0	-1.3	-1.4	-0.6	-0.9	-0.8	-1.0	-1.1	-0.9	-0.8	-1.0	-0.3
Angina	0.6	0.8	2.4	-1.3	-1.5	-0.8	-0.5	-1.1	-0.7	-0.4	-0.5	-1.5	-1.0	-1.0	-0.8	-0.9	-0.7	-0.8	-0.8	-0.5	-0.7	-0.7	-0.7	-0.8	-0.8	-0.7
Medication for hormone replacement therapy	1.0	1.1	3.0	-1.4	-1.7	-1.0	-0.8	-1.1	-1.1	-1.2	-0.8	-0.8	-1.3	-1.1	-0.9	-0.5	-0.3	-1.3	-1.0	-1.0	-0.9	-1.0	-0.9	-1.1	-1.0	-1.2
Vitamin and mineral supplements	0.9	1.2	4.8	-2.2	-1.7	-1.0	-1.1	-1.2	0.7	0.1	-1.0	-0.8	-1.2	-1.2	-1.0	-1.1	-1.4	-0.7	-0.9	-1.0	-1.0	-1.4	-0.9	-0.5	-1.0	-0.1
Supplements: Zinc	0.2	0.2	1.4	0.6	0.9	0.0	-0.0	0.2	-1.2	-0.7	0.1	-1.0	0.2	0.3	-0.1	-0.2	0.1	-0.1	0.0	0.1	-0.1	0.4	-0.1	-0.4	0.1	-0.5
Medication: Co-codamol	15.3	17.7	20.8	-3.7	-3.6	-4.3	-4.3	-4.4	-4.2	-4.0	-4.1	-3.5	-4.4	-4.4	-4.2	-4.2	-3.9	-4.6	-4.3	-4.2	-4.3	-4.3	-4.2	-4.5	-4.3	-4.6
Medication: Metformin	6.0	8.5	13.7	-3.5	-2.8	-3.0	-2.9	-3.1	-1.5	-2.2	-3.0	-2.9	-3.2	-3.1	-3.0	-3.5	-3.7	-2.4	-2.9	-2.5	-3.0	-3.1	-3.0	-2.7	-3.0	-2.1
Diabetes (father)	0.6	0.7	3.4	-1.9	-1.6	-0.6	-0.7	-0.9	0.4	0.2	-1.0	-0.1	-0.8	-1.0	-0.6	-0.9	-1.1	-0.4	-0.6	-0.4	-0.6	-1.2	-0.6	-0.2	-0.7	-0.3
Diabetes (mother)	4.7	6.0	9.6	-2.6	-1.5	-2.7	-2.6	-2.6	-1.5	-1.7	-2.6	-1.9	-2.3	-2.7	-2.7	-2.9	-3.1	-2.2	-2.6	-2.5	-2.6	-2.7	-2.5	-2.4	-2.7	-1.9
Severe depression (siblings)	0.6	0.7	1.6	0.0	0.1	1.1	1.0	1.0	-0.2	0.1	0.8	-0.5	1.3	1.0	1.0	0.7	0.9	0.5	1.0	1.0	1.0	0.9	0.9	0.7	1.1	0.1
Pack years adult smoking proportion	3.6	5.5	11.0	-1.1	-1.5	-2.2	-2.3	-2.3	-3.3	-3.0	-2.0	-3.2	-2.5	-2.2	-2.2	-2.3	-1.6	-2.5	-2.4	-2.1	-2.3	-1.7	-2.1	-2.7	-2.3	-2.7
Impedance of leg (right)	6.2	30.1	71.6	5.6	5.7	4.9	4.8	5.6	6.3	5.8	4.1	8.5	6.6	5.5	4.8	5.2	4.5	5.8	5.1	4.6	4.8	4.7	4.6	5.7	5.0	6.2
Leg fat-free mass (left)	11.4	60.3	77.6	-8.6	-8.3	-7.7	-7.6	-8.3	-6.6	-7.2	-7.4	-7.9	-8.8	-8.3	-7.6	-7.5	-7.0	-8.1	-7.8	-7.4	-7.6	-7.8	-7.5	-7.8	-7.8	-7.8
Trunk fat percentage	13.7	54.8	69.2	-8.3	-8.1	-7.8	-7.8	-8.1	-4.1	-5.1	-8.0	-4.1	-8.0	-8.1	-7.8	-7.5	-7.6	-7.5	-7.6	-7.9	-7.7	-8.3	-7.9	-6.9	-7.7	-6.2
Hand grip strength (right)	3.7	10.1	13.8	-2.6	-2.3	-3.4	-3.5	-3.5	-2.2	-3.0	-3.6	-1.3	-3.6	-3.5	-3.4	-2.6	-2.6	-3.5	-3.4	-3.7	-3.5	-3.5	-3.4	-3.1	-3.5	-3.0
Townsend deprivation index at recruitment	0.5	0.6	1.6	-0.6	-1.1	-0.6	-0.7	-0.7	-0.8	-0.8	-0.5	-0.9	-1.0	-0.7	-0.7	-1.3	-1.2	-0.6	-0.6	-0.4	-0.7	-0.8	-0.6	-0.8	-0.6	-0.7
Current tobacco smoking	3.7	6.0	9.5	-2.1	-2.3	-2.2	-2.4	-2.4	-3.1	-3.0	-2.1	-2.5	-2.5	-2.4	-2.3	-2.3	-1.8	-3.0	-2.3	-2.4	-2.3	-2.3	-2.3	-2.6	-2.2	-3.1
Average weekly fortified wine intake	1.0	1.1	2.8	-0.8	-0.6	-0.9	-0.9	-1.1	-1.5	-1.3	-0.8	-1.7	-1.0	-1.0	-0.9	-0.6	-0.4	-1.4	-1.0	-1.1	-0.9	-0.8	-0.9	-1.2	-0.9	-1.5
Maternal smoking around birth	9.6	13.9	18.0	-3.9	-3.9	-3.6	-3.7	-3.8	-3.5	-3.9	-3.2	-4.1	-4.2	-3.7	-3.6	-4.2	-3.9	-3.6	-3.7	-3.4	-3.6	-3.6	-3.5	-3.7	-3.7	-3.6
Fed-up feelings	15.2	27.6	33.7	-4.0	-4.7	-5.4	-5.6	-5.6	-5.0	-5.5	-5.6	-3.4	-5.3	-5.5	-5.4	-5.0	-4.4	-5.8	-5.5	-5.5	-5.5	-5.2	-5.4	-5.5	-5.5	-5.7
Frequency of unenthusiasm / disinterest in last 2 weeks	9.4	12.5	15.8	-3.3	-3.6	-3.6	-3.9	-3.6	-2.9	-3.6	-4.0	-2.1	-3.3	-3.6	-3.7	-3.8	-3.5	-3.5	-3.7	-3.7	-3.7	-3.6	-3.7	-3.5	-3.6	-3.4
Relative age voice broke	0.6	0.9	4.6	0.4	-0.2	0.8	0.7	0.5	-2.1	-1.2	0.9	-2.2	0.6	0.6	0.8	0.7	1.3	-0.2	0.6	0.6	0.7	1.1	0.8	-0.2	0.7	-1.0
Taking other prescription medications	25.4	39.2	45.4	-6.7	-6.6	-6.2	-6.2	-6.4	-5.5	-6.3	-6.3	-5.7	-6.3	-6.4	-6.2	-6.5	-6.2	-6.5	-6.2	-6.0	-6.2	-6.3	-6.2	-6.4	-6.2	-6.4
Age when periods started (menarche)	6.2	14.8	34.2	-2.4	-3.6	-3.4	-3.7	-3.6	-5.8	-5.3	-3.5	-3.9	-3.7	-3.5	-3.4	-3.0	-2.2	-4.7	-3.6	-3.6	-3.5	-3.2	-3.5	-4.4	-3.4	-5.5
Bilateral oophorectomy (both ovaries removed)	7.6	8.8	13.1	-3.4	-3.6	-2.9	-3.0	-3.0	-2.7	-2.7	-2.9	-2.9	-3.1	-2.9	-2.9	-3.0	-2.9	-3.0	-2.8	-2.9	-2.9	-3.0	-2.9	-3.1	-2.7	-3.0
Heel bone mineral density (BMD) T-score, automated (left)	7.2	16.3	27.1	-5.1	-4.0	-4.4	-4.4	-4.6	-0.1	-1.8	-4.6	-0.8	-4.4	-4.6	-4.3	-4.3	-5.2	-3.3	-4.2	-4.2	-4.4	-5.1	-4.4	-3.0	-4.4	-2.1
Tinnitus: Yes, but not now, but have in the past	5.0	5.4	7.3	-2.0	-2.6	-2.5	-2.5	-2.5	-1.7	-2.0	-2.5	-0.7	-2.3	-2.5	-2.5	-2.0	-2.0	-2.5	-2.5	-2.7	-2.5	-2.4	-2.4	-2.4	-2.5	-2.2
Qualifications: CSEs or equivalent	12.0	15.8	18.2	-3.9	-3.8	-4.1	-4.1	-4.1	-3.5	-3.7	-3.8	-3.2	-4.3	-4.1	-3.9	-4.1	-4.0	-4.1	-4.1	-3.9	-4.0	-4.1	-3.9	-4.3	-4.1	-4.1
Serious illness, injury or assault to yourself	0.0	0.1	0.4	0.1	-0.5	0.2	0.1	0.1	-0.3	-0.2	0.2	-0.6	-0.1	0.2	0.1	0.3	0.3	0.1	0.1	0.2	0.1	0.4	0.1	0.1	0.2	-0.0
High blood pressure	0.9	2.6	5.3	-1.6	-1.3	-1.6	-1.5	-1.6	-1.7	-1.2	-1.4	-2.3	-1.7	-1.6	-1.6	-1.9	-1.8	-1.4	-1.6	-1.1	-1.6	-1.5	-1.5	-1.8	-1.6	-1.6
Hayfever, allergic rhinitis or eczema	0.3	0.7	3.3	0.2	-0.6	0.8	0.7	0.8	0.2	0.5	0.7	0.6	0.8	0.8	0.7	1.7	1.8	0.3	0.7	0.4	0.7	1.0	0.7	0.7	0.7	0.4
Multivitamins +/- minerals	0.5	0.6	4.0	2.0	1.5	0.6	0.7	0.7	-0.9	-0.2	0.7	0.6	0.8	0.7	0.6	0.7	1.0	0.2	0.5	0.6	0.6	0.9	0.5	0.1	0.6	-0.3
Stomach or abdominal pain in last month	1.8	2.3	4.6	-0.7	-1.3	-1.5	-1.6	-1.4	-2.1	-1.7	-1.7	-0.8	-1.1	-1.5	-1.6	-1.4	-0.9	-1.8	-1.6	-1.5	-1.6	-1.4	-1.6	-1.7	-1.5	-2.0
Supplements: Glucosamine	1.0	1.3	2.4	1.5	1.2	1.1	1.1	1.1	0.9	0.9	1.1	1.5	1.1	1.1	1.2	1.4	1.3	1.0	1.1	1.0	1.1	1.1	1.1	1.1	1.1	1.0
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.3	1.1	0.5	0.2	0.1	0.2	-1.0	-1.1	0.2	-0.0	0.4	0.2	0.2	0.5	0.8	-0.1	0.1	0.2	0.1	0.5	0.2	-0.2	0.2	-0.4
Medication: Atenolol	2.8	3.6	4.7	-2.1	-2.0	-1.9	-1.9	-2.1	-1.5	-1.5	-2.0	-1.4	-2.0	-2.1	-1.9	-1.7	-1.6	-2.2	-1.9	-1.9	-1.9	-2.1	-1.9	-1.8	-1.9	-2.0
Medication: Levothyroxine sodium	0.9	1.4	2.7	-1.0	-0.8	-1.2	-1.0	-1.1	-1.4	-1.4	-1.0	-1.6	-0.9	-1.1	-1.2	-1.6	-1.5	-1.1	-1.2	-0.8	-1.1	-1.1	-1.1	-1.3	-1.1	-1.4
Sitting height	0.1	0.5	1.5	-1.1	-1.2	-0.8	-0.6	-0.9	0.7	0.1	-0.7	0.4	-1.2	-1.0	-0.6	0.1	-0.2	-0.5	-0.7	-0.7	-0.6	-0.7	-0.6	-0.3	-0.8	0.1
Chronic bronchitis/emphysema (father)	2.4	2.8	8.0	-2.1	-2.3	-1.3	-1.3	-1.6	-2.3	-1.5	-1.2	-2.8	-1.5	-1.6	-1.2	-1.1	-0.7	-2.1	-1.4	-1.4	-1.2	-1.3	-1.2	-1.8	-1.3	-2.3
High blood pressure (mother)	0.1	0.1	0.4	-0.2	0.5	0.2	0.2	0.2	0.4	0.6	0.1	-0.4	0.2	0.2	0.1	-0.3	-0.4	0.5	0.2	0.6	0.2	0.0	0.2	0.2	0.2	0.4
Body mass index (BMI)	28.8	122.7	151.3	-11.8	-11.7	-11.1	-11.1	-11.8	-9.1	-9.6	-10.7	-10.4	-12.3	-11.8	-11.1	-11.3	-10.7	-11.4	-11.2	-10.8	-11.1	-11.4	-11.0	-11.0	-11.1	-10.8
Impedance of leg (left)	7.0	34.2	77.6	5.9	6.2	5.3	5.1	5.9	6.7	6.2	4.5	8.8	7.0	5.8	5.2	5.5	4.7	6.2	5.5	5.0	5.2	5.0	5.0	6.2	5.4	6.7
Leg predicted mass (left)	11.2	59.6	76.6	-8.5	-8.2	-7.7	-7.6	-8.2	-6.6	-7.2	-7.3	-7.9	-8.8	-8.2	-7.5	-7.5	-7.0	-8.0	-7.7	-7.4	-7.5	-7.7	-7.5	-7.7	-7.7	-7.8
Trunk fat mass	18.0	77.2	96.4	-9.8	-9.4	-9.1	-9.1	-9.5	-5.8	-6.8	-9.1	-6.2	-9.6	-9.5	-9.1	-8.9	-8.8	-9.0	-9.0	-9.0	-9.0	-9.5	-9.1	-8.4	-9.1	-7.9
Waist circumference	18.0	65.9	92.3	-9.6	-8.7	-8.2	-8.2	-8.7	-5.6	-6.6	-8.2	-6.9	-8.9	-8.7	-8.3	-8.4	-8.3	-8.0	-8.1	-7.8	-8.2	-8.7	-8.2	-7.7	-8.2	-7.4
Number of incorrect matches in round	0.2	0.3	1.6	1.2	0.1	0.1	0.1	0.1	-1.1	-0.9	0.5	-0.9	-0.2	0.2	0.1	0.8	1.3	-0.1	0.0	-0.1	0.1	0.9	0.2	-0.4	0.1	-0.2
Past tobacco smoking	1.2	2.1	12.3	-0.2	0.8	0.9	1.0	0.8	3.5	2.1	0.6	2.6	1.4	0.7	1.1	1.1	0.3	1.6	1.1	0.9	1.0	0.4	1.0	1.9	0.9	2.5
Alcohol usually taken with meals	5.0	8.0	9.4	2.8	2.7	2.8	2.9	2.9	2.6	3.0	2.6	2.9	2.9	2.8	2.9	3.1	2.8	2.9	2.7	2.8	2.8	2.7	2.8	2.9	2.7	3.0
Nervous feelings	0.5	0.9	1.8	-1.2	-0.3	-1.0	-1.0	-1.0	-0.2	-0.7	-1.4	-0.1	-0.3	-1.1	-0.9	-1.3	-1.3	-0.6	-1.0	-0.8	-1.0	-1.1	-1.0	-0.7	-1.1	-0.5
Frequency of tenseness / restlessness in last 2 weeks	10.1	15.7	26.4	-3.4	-3.9	-3.7	-4.0	-3.8	-4.7	-5.1	-3.9	-4.3	-3.7	-3.8	-3.8	-3.7	-3.0	-4.2	-3.9	-3.8	-3.8	-3.4	-3.7	-4.3	-3.7	-4.6
Hearing difficulty/problems with background noise	0.5	0.9	4.8	0.6	0.4	0.9	0.9	0.7	-1.2	-0.4	1.3	-2.2	0.7	0.8	0.8	0.5	0.9	0.4	0.8	1.0	0.9	1.3	1.0	0.2	0.9	-0.2
Hair/balding pattern: Pattern 2	3.0	3.8	8.3	-2.9	-2.7	-1.8	-1.7	-1.9	-1.7	-2.3	-1.9	-2.5	-1.9	-1.9	-1.7	-2.0	-1.7	-1.8	-1.8	-1.5	-1.7	-1.8	-1.7	-1.9	-1.7	-1.9
Had menopause	2.8	3.5	5.9	0.6	0.9	2.2	2.4	2.0	1.5	1.6	2.3	-0.2	1.7	1.9	2.2	1.8	1.7	1.9	2.2	2.4	2.2	1.9	2.1	1.9	2.2	1.6
Had other major operations	1.3	1.6	8.7	-2.0	-2.9	-0.6	-0.6	-0.9	-1.9	-1.9	-0.5	-2.3	-1.2	-0.9	-0.5	-0.7	-0.3	-1.2	-0.7	-0.4	-0.5	-0.6	-0.6	-1.1	-0.6	-1.6
Forced vital capacity (FVC)	4.0	15.5	22.1	2.4	2.5	4.0	4.0	4.0	4.7	4.5	3.7	3.8	3.7	3.9	4.1	4.2	3.6	4.3	4.0	4.1	4.0	3.5	4.0	4.5	3.9	4.5
Heel bone mineral density (BMD) T-score, automated (right)	5.2	12.0	23.1	-4.8	-3.6	-3.7	-3.8	-3.9	0.7	-0.8	-4.0	0.1	-3.5	-3.9	-3.7	-3.7	-4.8	-2.7	-3.4	-3.6	-3.7	-4.6	-3.8	-2.2	-3.7	-1.4
Ever unenthusiastic/disinterested for a whole week	9.5	11.6	22.0	-3.1	-3.7	-3.1	-3.0	-3.2	-4.7	-4.3	-3.1	-4.4	-3.0	-3.3	-3.1	-3.2	-2.4	-3.7	-3.3	-2.8	-3.0	-2.7	-3.0	-3.7	-3.2	-4.4
Qualifications: None of the above	21.2	45.3	55.2	-5.6	-5.2	-6.8	-6.9	-7.0	-6.8	-6.6	-6.8	-5.6	-6.9	-7.0	-7.0	-6.8	-6.2	-7.4	-6.9	-6.8	-6.9	-6.9	-7.0	-7.1	-6.8	-7.4
Financial difficulties in last 2 years	3.6	4.8	5.8	-1.9	-2.0	-2.2	-2.3	-2.4	-2.1	-2.0	-2.3	-1.8	-2.2	-2.4	-2.2	-2.2	-2.0	-2.3	-2.3	-2.1	-2.3	-2.2	-2.2	-2.2	-2.3	-2.2
Mouth/teeth dental problems	1.8	2.8	5.8	2.2	2.3	1.4	1.4	1.6	1.8	1.2	1.3	2.4	1.8	1.6	1.4	1.8	1.4	1.8	1.4	1.2	1.4	1.6	1.4	1.7	1.4	1.9
Heart attack	4.9	6.2	9.1	-2.4	-2.4	-2.6	-2.6	-2.6	-1.8	-2.3	-2.5	-1.8	-2.8	-2.6	-2.6	-3.0	-3.0	-2.3	-2.5	-2.3	-2.6	-2.7	-2.6	-2.5	-2.5	-2.2
Allergy	1.5	3.4	8.7	2.5	2.9	1.6	1.7	1.7	2.2	2.0	1.7	2.0	1.7	1.7	1.6	1.0	0.7	2.1	1.7	1.8	1.6	1.3	1.7	1.9	1.6	2.3
Pain all over the body in last month	9.9	10.6	16.4	-2.6	-3.1	-3.1	-3.4	-3.2	-4.1	-3.9	-3.1	-3.4	-3.1	-3.2	-3.2	-2.7	-2.2	-3.7	-3.2	-3.3	-3.2	-2.9	-3.1	-3.6	-3.1	-3.9
Diabetes (self-reported)	12.9	19.8	30.5	-5.3	-3.9	-4.6	-4.5	-4.8	-2.6	-3.3	-4.7	-4.0	-4.6	-4.8	-4.6	-5.4	-5.5	-3.8	-4.5	-4.0	-4.6	-4.9	-4.6	-4.2	-4.6	-3.6
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	1.2	0.2	0.1	0.3	0.2	0.4	0.7	0.4	0.0	1.1	0.6	0.4	0.3	0.5	0.5	0.2	0.4	0.1	0.3	0.2	0.1	0.6	0.4	0.4
Medication: Ramipril	4.1	5.2	8.6	-2.1	-1.7	-2.2	-2.3	-2.2	-2.5	-2.3	-2.0	-2.9	-2.3	-2.2	-2.2	-2.9	-2.7	-2.0	-2.3	-1.9	-2.2	-2.0	-2.1	-2.4	-2.2	-2.4
Medication: Simvastatin	0.9	1.3	3.0	-1.7	-1.3	-1.2	-1.1	-1.2	-0.3	-0.2	-1.0	-1.5	-1.5	-1.2	-1.2	-1.3	-1.4	-0.9	-1.1	-1.0	-1.1	-1.2	-1.1	-1.1	-1.1	-0.6
Fluid intelligence score	29.3	60.8	69.5	7.5	7.2	8.2	8.1	8.3	6.5	7.0	7.9	6.1	8.2	8.3	8.1	7.8	7.5	8.0	8.2	8.1	8.1	7.9	8.0	8.0	8.2	7.5
Illnesses of siblings	3.0	4.2	6.1	2.3	2.5	2.0	1.9	2.1	2.1	1.8	2.0	2.5	1.9	2.1	1.9	2.2	1.8	1.9	2.1	1.5	2.0	1.8	2.0	2.2	2.0	2.1
Neuroticism score	8.1	16.9	19.6	-3.9	-3.8	-4.1	-4.3	-4.2	-4.0	-4.4	-4.3	-3.6	-3.7	-4.3	-4.1	-4.4	-3.8	-4.2	-4.2	-3.9	-4.2	-4.0	-4.1	-4.2	-4.2	-4.3
Weight	20.4	100.2	123.2	-11.0	-10.6	-10.1	-10.0	-10.7	-8.0	-8.8	-9.8	-9.2	-11.1	-10.7	-10.0	-10.0	-9.6	-10.3	-10.1	-9.7	-10.0	-10.3	-10.0	-9.9	-10.1	-9.7
Impedance of arm (right)	16.7	77.6	136.9	8.8	8.7	8.3	8.2	9.1	9.6	9.2	7.5	11.7	9.8	9.0	8.2	8.9	7.9	9.0	8.5	7.4	8.2	8.1	8.0	9.3	8.3	9.8
Arm fat percentage (right)	17.8	70.3	83.7	-9.1	-8.9	-8.7	-8.6	-9.1	-5.8	-6.5	-8.6	-6.0	-9.1	-9.0	-8.6	-8.5	-8.4	-8.7	-8.6	-8.7	-8.6	-9.1	-8.6	-8.1	-8.6	-7.7
Trunk fat-free mass	8.1	46.4	65.7	-7.2	-6.8	-6.6	-6.5	-7.1	-6.9	-7.1	-6.1	-8.1	-7.6	-7.1	-6.5	-6.6	-5.8	-7.0	-6.8	-6.0	-6.5	-6.4	-6.4	-7.1	-6.7	-7.4
Hip circumference	10.6	45.8	58.8	-7.1	-7.2	-6.7	-6.7	-7.3	-6.0	-6.0	-6.5	-6.7	-7.7	-7.2	-6.7	-6.6	-6.1	-7.2	-6.8	-6.5	-6.7	-6.9	-6.7	-6.8	-6.7	-6.9
Time employed in main current job	1.5	1.7	2.3	1.1	0.9	1.4	1.4	1.3	1.3	1.5	1.3	0.6	1.2	1.3	1.4	1.3	1.0	1.5	1.4	1.3	1.4	1.4	1.4	1.5	1.4	1.5
Alcohol intake versus 10 years previously	18.4	27.6	34.9	-5.8	-5.7	-5.4	-5.6	-5.6	-3.1	-4.7	-5.7	-2.8	-5.6	-5.6	-5.4	-5.3	-5.6	-5.2	-5.3	-5.5	-5.4	-5.9	-5.4	-4.8	-5.4	-4.6
Father’s age at death	10.4	14.0	18.4	2.6	3.2	3.9	4.0	3.9	3.5	4.3	3.7	2.5	3.7	3.9	4.0	3.8	3.4	3.9	4.0	4.0	3.9	3.6	3.8	4.0	3.9	3.7
Worrier / anxious feelings	2.1	3.9	6.2	-2.5	-2.1	-2.0	-2.1	-2.2	-1.1	-1.5	-2.4	-1.0	-1.5	-2.2	-2.1	-2.1	-2.2	-1.8	-2.1	-2.0	-2.1	-2.1	-2.1	-1.7	-2.1	-1.6
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.0	12.1	0.4	-1.0	-0.8	-0.8	-0.8	-3.5	-2.9	-0.8	-1.9	-0.5	-0.7	-0.9	-0.5	0.4	-1.8	-0.9	-0.8	-0.8	-0.3	-0.9	-1.8	-0.7	-2.8
Falls in the last year	1.3	1.8	7.1	-1.6	-1.3	-1.1	-1.0	-1.3	-1.8	-1.4	-0.8	-2.7	-1.4	-1.2	-1.1	-1.3	-1.0	-1.3	-1.1	-0.8	-1.1	-1.0	-1.1	-1.4	-1.1	-1.6
Hair/balding pattern: Pattern 3	2.0	2.9	8.5	2.9	2.9	1.3	1.4	1.5	1.3	2.1	1.4	2.8	1.7	1.5	1.3	1.9	1.8	1.3	1.3	1.0	1.3	1.5	1.3	1.4	1.3	1.5
Number of live births	6.0	8.5	13.2	-3.6	-3.6	-2.8	-2.8	-3.1	-1.9	-2.1	-2.8	-2.6	-3.5	-3.1	-2.8	-3.0	-3.0	-3.0	-2.8	-2.7	-2.8	-3.2	-2.9	-2.7	-2.8	-2.7
Forced expiratory volume in 1-second (FEV1)	6.1	20.7	35.0	2.3	2.6	4.6	4.6	4.5	5.9	5.5	4.2	4.6	4.3	4.4	4.7	4.6	3.6	5.1	4.7	4.8	4.7	3.8	4.6	5.4	4.5	5.2
Pulse rate	1.6	2.7	6.0	-2.1	-1.4	-1.7	-1.6	-1.5	2.5	0.6	-2.0	2.3	-1.2	-1.6	-1.6	-1.6	-2.4	-0.5	-1.4	-1.6	-1.6	-2.3	-1.6	-0.2	-1.7	0.7
Happiness	0.5	0.6	1.4	0.9	0.7	0.8	0.8	0.9	-0.2	-0.5	0.8	-0.4	1.2	0.9	0.8	0.2	0.5	0.9	0.7	1.1	0.8	1.1	0.8	0.5	0.8	0.4
Noisy workplace	4.2	5.2	8.8	-2.7	-3.0	-2.0	-2.2	-2.3	-2.1	-2.6	-2.3	-2.3	-2.3	-2.3	-2.1	-2.1	-1.9	-2.5	-2.1	-2.1	-2.1	-2.4	-2.1	-2.1	-2.0	-2.5
Qualifications: A levels/AS levels or equivalent	41.5	92.0	106.1	8.9	8.6	10.0	10.0	10.3	7.9	8.7	9.7	6.8	10.2	10.2	9.9	9.7	9.4	10.2	10.0	10.0	10.0	10.0	9.9	9.8	10.0	9.6
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	3.9	0.5	0.0	0.1	0.2	-0.1	-1.7	-1.2	0.5	-2.0	-0.3	0.0	0.1	0.3	0.7	-0.4	-0.1	0.2	0.1	0.6	0.1	-0.5	-0.0	-1.0
Mouth/teeth dental problems: Dentures	10.3	17.4	21.0	-4.2	-4.5	-4.1	-4.0	-4.4	-4.2	-4.0	-3.9	-4.2	-4.5	-4.4	-4.0	-4.0	-3.5	-4.6	-4.2	-4.0	-4.0	-4.1	-3.9	-4.4	-4.1	-4.5
Asthma	5.5	10.8	17.5	-4.2	-4.2	-3.1	-3.0	-3.3	-3.2	-3.2	-3.1	-3.8	-3.4	-3.3	-3.0	-3.0	-2.6	-3.5	-3.1	-3.0	-3.0	-3.0	-3.1	-3.4	-3.0	-3.6
Medication: Ibuprofen (e.g. Nurofen)	2.8	3.6	4.9	-1.5	-1.6	-1.9	-1.8	-2.0	-2.0	-1.7	-1.9	-1.8	-2.0	-2.0	-1.9	-2.0	-1.9	-2.0	-1.9	-1.7	-1.9	-1.9	-1.9	-2.0	-1.9	-2.2
Medication: Cholesterol lowering	4.2	6.5	9.0	-2.7	-2.3	-2.8	-2.7	-2.8	-1.5	-1.5	-2.6	-1.8	-3.0	-2.7	-2.8	-2.9	-3.0	-2.3	-2.6	-2.5	-2.7	-2.9	-2.7	-2.5	-2.7	-2.1
Depression (self-reported)	0.9	1.0	2.8	0.5	-0.7	1.3	1.1	1.1	-0.4	-0.0	1.1	-0.1	1.1	1.1	1.3	1.4	1.7	0.5	1.2	1.1	1.2	1.1	1.3	0.6	1.3	0.1
Medication: Lansoprazole	3.4	3.8	9.0	-2.4	-3.0	-1.9	-1.9	-2.0	-1.0	-1.7	-2.0	-1.2	-2.2	-2.1	-1.9	-1.8	-2.0	-1.8	-1.9	-1.7	-1.9	-2.1	-2.0	-1.7	-1.9	-1.7
Prospective memory result	6.8	8.4	13.8	-3.6	-3.7	-2.9	-2.8	-3.2	-1.9	-2.3	-2.9	-2.4	-3.1	-3.2	-2.9	-2.7	-2.6	-3.1	-2.9	-3.1	-2.8	-2.9	-2.8	-2.7	-3.0	-2.6
Lung cancer (father)	4.3	5.0	6.0	-2.0	-2.3	-2.4	-2.3	-2.4	-1.5	-2.2	-2.4	-1.2	-2.5	-2.4	-2.4	-2.2	-2.1	-2.3	-2.4	-2.3	-2.3	-2.4	-2.4	-2.1	-2.4	-2.0
Illnesses of mother	2.9	3.6	6.4	2.1	1.2	2.0	2.0	2.0	1.0	1.1	2.1	1.5	2.0	2.0	2.0	2.4	2.5	1.5	2.0	1.6	2.0	2.1	2.0	1.8	2.0	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	6.5	20.6	31.8	2.8	3.0	4.6	4.6	4.5	5.6	5.2	4.2	4.3	4.3	4.5	4.7	4.5	3.8	5.1	4.7	4.7	4.7	4.0	4.6	5.2	4.6	5.3
Pulse wave Arterial Stiffness index	1.1	1.3	2.2	-1.2	-0.9	-1.1	-1.2	-1.1	-1.3	-0.9	-1.1	-1.5	-1.1	-1.1	-1.2	-1.2	-1.1	-1.2	-1.0	-1.1	-1.1	-1.1	-1.2	-1.1	-1.0	-1.3
Impedance of arm (left)	16.5	76.3	132.2	8.5	8.4	8.2	8.2	9.0	9.7	9.2	7.4	11.5	9.6	8.9	8.1	8.8	7.8	9.0	8.5	7.4	8.1	8.0	7.9	9.3	8.3	9.8
Arm fat mass (right)	23.8	98.1	118.8	-10.8	-10.4	-10.1	-10.1	-10.7	-7.4	-8.2	-9.9	-8.0	-10.9	-10.6	-10.0	-10.0	-9.7	-10.3	-10.1	-10.0	-10.0	-10.5	-10.1	-9.7	-10.1	-9.4
Trunk predicted mass	7.9	44.9	64.2	-7.1	-6.6	-6.5	-6.4	-7.0	-6.7	-6.9	-6.0	-8.0	-7.4	-7.0	-6.4	-6.5	-5.8	-6.9	-6.6	-5.9	-6.4	-6.3	-6.3	-7.0	-6.6	-7.2
Standing height	0.1	0.5	1.2	0.1	1.0	0.6	0.6	0.7	0.9	0.3	0.3	1.1	0.9	0.6	0.6	0.9	0.9	0.8	0.6	0.7	0.6	0.6	0.6	0.7	0.5	0.8
Length of working week for main job	0.4	0.5	1.3	0.1	0.2	-0.9	-0.8	-0.7	0.1	-0.3	-0.9	0.4	-0.8	-0.7	-0.8	-1.1	-0.9	-0.3	-0.8	-0.6	-0.8	-0.8	-0.8	-0.6	-0.9	-0.0
Exposure to tobacco smoke at home	19.7	22.2	28.1	-3.7	-3.0	-4.7	-4.7	-4.7	-5.2	-5.1	-4.5	-5.2	-4.7	-4.6	-4.8	-5.2	-4.6	-4.8	-4.8	-4.5	-4.8	-4.3	-4.7	-5.1	-4.7	-5.3
Breastfed as a baby	5.0	6.2	9.1	3.0	2.6	2.5	2.6	2.6	1.9	1.9	2.6	2.3	2.2	2.6	2.4	3.0	3.0	2.3	2.5	2.2	2.5	2.6	2.4	2.5	2.5	2.2
Tense / ‘highly strung’	2.4	4.0	5.6	-2.0	-2.4	-1.9	-2.1	-2.0	-2.4	-2.4	-2.1	-2.0	-1.5	-2.0	-2.0	-2.0	-1.4	-2.1	-2.0	-1.9	-2.0	-1.7	-1.9	-2.1	-1.9	-2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	3.8	5.8	12.9	-2.5	-3.3	-2.0	-2.1	-2.2	-3.5	-3.1	-1.8	-3.6	-2.1	-2.2	-2.0	-2.1	-1.4	-2.7	-2.1	-2.0	-2.0	-1.7	-1.9	-2.6	-2.0	-3.1
Hair/balding pattern: Pattern 4	0.3	0.7	1.9	-0.4	-1.2	-0.9	-0.9	-0.9	0.1	-0.4	-0.8	0.4	-1.4	-0.8	-0.9	-0.7	-0.9	-0.7	-0.9	-0.8	-0.9	-1.0	-0.9	-0.5	-0.9	-0.4
Birth weight of first child	0.9	1.6	2.6	1.3	0.7	1.4	1.3	1.4	0.6	0.4	1.5	0.2	0.9	1.5	1.4	1.4	1.5	1.3	1.3	1.3	1.4	1.6	1.4	1.1	1.3	1.2
Peak expiratory flow (PEF)	4.0	9.2	12.4	1.9	1.6	3.2	3.2	3.1	3.4	3.3	3.0	2.2	2.6	3.1	3.2	2.9	2.4	3.5	3.3	3.5	3.2	2.8	3.2	3.5	3.2	3.4
Pulse wave reflection index	1.6	1.9	12.2	-1.0	-1.1	-0.7	-0.8	-1.0	-3.0	-1.9	-0.6	-3.5	-1.2	-0.8	-0.7	-1.1	-0.6	-1.3	-0.9	-0.7	-0.8	-0.4	-0.8	-1.5	-0.7	-2.1
Ever highly irritable/argumentative for 2 days	13.2	15.9	27.8	-4.6	-5.3	-3.7	-3.7	-4.1	-4.2	-4.0	-3.8	-4.3	-4.0	-4.1	-3.7	-3.6	-2.9	-4.3	-3.8	-3.5	-3.7	-3.7	-3.7	-4.1	-3.7	-4.5
Loud music exposure frequency	0.8	0.8	1.8	0.5	1.0	1.0	1.1	1.0	0.7	0.9	0.8	0.3	1.2	1.0	1.0	0.5	0.5	1.1	1.0	1.4	1.0	0.8	0.9	0.9	1.0	0.8
Qualifications: O levels/GCSEs or equivalent	8.5	13.5	16.9	2.9	2.8	3.7	3.7	3.8	3.8	3.7	3.5	3.7	3.8	3.7	3.8	3.8	3.5	4.1	3.6	3.8	3.7	3.6	3.7	3.9	3.6	4.1
Mouth/teeth dental problems: Bleeding gums	1.3	1.6	3.3	1.5	1.8	1.3	1.4	1.5	0.5	0.8	1.2	0.3	1.4	1.6	1.3	0.9	1.1	1.3	1.3	1.5	1.3	1.4	1.2	1.0	1.4	0.9
Blood clot in the leg (DVT)	0.3	0.4	2.0	-1.3	-1.4	-0.3	-0.6	-0.5	-0.5	-0.5	-0.5	-0.7	-0.4	-0.5	-0.3	-0.4	-0.4	-0.6	-0.3	-0.3	-0.3	-0.6	-0.3	-0.4	-0.3	-0.7
Medication: Paracetamol	5.5	9.0	20.8	-1.2	-1.9	-2.8	-3.0	-2.8	-4.6	-4.0	-2.9	-2.8	-2.7	-2.8	-2.9	-2.8	-2.0	-3.5	-3.0	-2.8	-2.9	-2.4	-2.9	-3.7	-2.8	-4.1
Headache pain in last month	0.6	1.0	1.7	-0.6	-0.9	-1.0	-1.0	-1.0	-1.3	-1.3	-1.1	-0.7	-1.0	-1.0	-1.0	-0.8	-0.6	-1.2	-1.0	-1.0	-1.0	-0.9	-1.0	-1.1	-1.0	-1.3
Medication for cholesterol, blood pressure or diabetes	9.2	15.3	19.0	4.2	3.6	4.1	4.1	4.2	2.6	2.8	4.1	3.1	4.3	4.1	4.2	4.3	4.4	3.7	4.0	3.9	4.1	4.2	4.1	3.9	4.0	3.4
Glaucoma (self-reported)	1.5	1.8	3.1	0.2	0.2	1.4	1.5	1.2	1.4	1.7	1.6	-0.2	1.2	1.2	1.4	1.1	1.0	1.6	1.4	1.8	1.4	1.4	1.4	1.4	1.4	1.7
Gout (self-reported)	1.6	2.2	4.5	-2.1	-1.5	-1.5	-1.5	-1.5	-0.8	-0.9	-1.6	-1.3	-1.5	-1.6	-1.5	-1.7	-1.7	-1.4	-1.4	-1.4	-1.5	-1.7	-1.5	-1.3	-1.5	-1.1
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	3.6	-1.1	-1.0	-0.9	-0.7	-0.9	-1.5	-1.4	-0.7	-1.9	-0.9	-1.0	-0.9	-1.3	-1.1	-0.9	-1.0	-0.5	-0.9	-0.8	-0.8	-1.3	-1.0	-1.3
Medication: Amlodipine	0.5	0.7	2.0	-0.8	-0.8	-0.8	-0.9	-0.9	-0.7	-0.7	-0.7	-1.4	-1.0	-0.8	-0.8	-1.2	-1.1	-0.6	-0.8	-0.7	-0.8	-0.7	-0.7	-0.9	-0.8	-0.6
Medication: Ventolin 100micrograms inhaler	10.9	14.0	18.5	-4.3	-3.8	-4.0	-3.6	-4.0	-2.3	-3.0	-4.1	-2.5	-4.1	-4.1	-3.8	-3.8	-3.8	-3.7	-4.0	-3.6	-3.8	-4.1	-3.9	-3.6	-4.0	-3.5
Birth weight	0.6	1.3	3.5	1.9	1.4	1.0	1.2	1.1	0.8	0.8	1.1	1.2	0.7	1.1	1.1	1.4	1.4	1.0	1.0	1.1	1.1	1.2	1.0	1.0	1.0	0.9
Chronic bronchitis/emphysema (mother)	12.6	14.7	17.1	-4.1	-3.8	-3.8	-3.7	-4.0	-3.6	-3.6	-3.7	-3.6	-4.1	-4.0	-3.7	-3.9	-3.8	-3.9	-3.9	-3.5	-3.8	-3.8	-3.8	-3.9	-3.9	-4.0
High blood pressure (siblings)	2.6	3.7	4.9	-2.2	-2.0	-1.9	-1.9	-2.0	-1.9	-1.6	-2.1	-2.0	-1.9	-2.1	-1.9	-1.8	-1.5	-2.0	-2.0	-1.7	-1.9	-1.9	-1.9	-1.9	-1.9	-2.1
Forced vital capacity (FVC), Best measure	4.6	16.8	22.0	3.0	3.1	4.1	4.1	4.1	4.7	4.4	3.9	3.8	3.8	4.1	4.2	4.3	3.8	4.5	4.2	4.2	4.2	3.8	4.2	4.5	4.1	4.7
Body fat percentage	17.6	69.5	84.6	-9.2	-9.0	-8.7	-8.7	-9.0	-5.2	-6.2	-8.8	-5.3	-9.0	-9.0	-8.7	-8.5	-8.4	-8.5	-8.5	-8.7	-8.7	-9.2	-8.7	-7.9	-8.6	-7.3
Leg fat percentage (right)	24.5	88.8	104.0	-10.1	-9.9	-9.7	-9.7	-10.2	-6.9	-7.7	-9.7	-7.1	-10.1	-10.1	-9.7	-9.6	-9.3	-9.7	-9.7	-9.5	-9.7	-10.1	-9.7	-9.2	-9.7	-8.8
Arm fat-free mass (right)	13.9	71.4	89.3	-9.2	-8.8	-8.3	-8.2	-8.9	-7.8	-8.2	-7.8	-9.3	-9.4	-8.9	-8.2	-8.3	-7.6	-8.6	-8.4	-7.7	-8.2	-8.2	-8.1	-8.6	-8.4	-8.7
Exposure to tobacco smoke outside home	11.5	15.3	18.7	-3.6	-3.6	-3.8	-3.9	-4.0	-3.8	-4.2	-3.8	-3.9	-4.1	-3.9	-3.9	-4.1	-3.8	-4.1	-3.8	-3.8	-3.9	-3.8	-3.9	-4.0	-3.8	-4.3
Comparative body size at age 10	1.4	3.9	11.1	-1.3	-1.5	-1.7	-1.5	-1.9	-2.6	-2.2	-1.2	-3.3	-2.5	-1.8	-1.6	-2.0	-1.6	-2.2	-1.8	-1.6	-1.6	-1.5	-1.6	-2.2	-1.7	-2.6
Number of full brothers	4.9	6.2	12.2	-1.8	-2.3	-2.3	-2.2	-2.5	-3.5	-3.1	-2.1	-3.2	-2.4	-2.4	-2.3	-2.4	-1.6	-2.8	-2.4	-2.1	-2.2	-2.0	-2.3	-2.9	-2.3	-3.2
Worry too long after embarrassment	0.8	1.4	2.7	0.7	1.6	1.1	1.2	1.2	0.9	1.2	1.2	-0.5	1.6	1.2	1.2	0.5	0.5	1.5	1.1	1.4	1.1	1.4	1.2	1.2	1.1	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	6.8	-1.4	-2.3	-1.1	-1.3	-1.2	-2.6	-2.5	-1.2	-2.3	-1.0	-1.2	-1.2	-1.1	-0.4	-1.7	-1.2	-1.2	-1.2	-0.8	-1.1	-1.7	-1.1	-2.0
Wheeze or whistling in the chest in last year	22.9	40.9	46.2	-6.7	-6.8	-6.4	-6.4	-6.7	-6.0	-6.2	-6.3	-6.1	-6.7	-6.7	-6.3	-6.1	-5.5	-6.8	-6.4	-6.4	-6.3	-6.2	-6.3	-6.6	-6.4	-6.6
Number of children fathered	3.9	4.4	6.5	-2.5	-2.5	-2.0	-2.0	-2.2	-1.6	-2.0	-2.1	-1.5	-2.4	-2.2	-2.0	-1.8	-1.7	-2.4	-2.0	-2.1	-2.0	-2.3	-2.1	-2.0	-2.0	-2.2
Reason for reducing amount of alcohol drunk: Health precaution	3.1	3.6	5.6	1.3	0.8	2.0	1.9	2.0	2.2	1.9	1.8	1.7	1.9	2.0	2.0	1.9	1.8	2.2	2.0	1.8	1.9	2.0	2.0	2.2	1.9	2.4
Age at first live birth	28.0	49.6	57.0	7.6	7.5	7.0	7.0	7.3	6.2	7.0	6.7	6.6	7.5	7.2	6.9	7.4	7.0	7.2	6.9	6.5	7.0	7.2	7.0	7.2	6.9	7.2
Pulse wave peak to peak time	1.2	1.4	2.5	1.2	1.0	1.0	1.2	1.1	1.4	1.0	1.1	1.6	1.1	1.1	1.2	1.2	1.1	1.3	1.0	1.1	1.1	1.2	1.2	1.2	1.0	1.4
Health satisfaction	12.5	16.2	20.2	-3.5	-3.5	-4.1	-4.1	-4.1	-4.0	-4.5	-4.1	-3.8	-3.8	-4.1	-4.1	-4.3	-3.7	-4.1	-4.2	-3.9	-4.1	-3.7	-4.1	-4.3	-4.1	-4.1
Shortness of breath walking on level ground	7.4	8.8	13.5	-3.3	-3.7	-2.9	-2.8	-3.1	-2.7	-3.1	-2.8	-2.8	-3.2	-3.1	-2.9	-2.6	-2.3	-3.1	-3.0	-2.8	-2.9	-2.9	-2.9	-3.0	-3.0	-3.2
Qualifications: College or University degree	41.4	130.4	156.2	10.1	10.3	11.8	11.8	12.2	10.1	10.5	11.6	7.8	12.3	12.2	11.7	11.1	10.3	12.5	11.9	11.8	11.8	12.0	11.8	11.9	11.9	12.1
Eye problems/disorders: None of the above	0.4	0.5	2.1	1.2	0.7	0.4	0.4	0.5	0.2	0.6	0.6	1.2	0.2	0.5	0.4	1.4	1.5	0.1	0.4	-0.0	0.4	0.6	0.5	0.3	0.4	0.3
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.6	-1.6	-1.6	-1.3	-1.2	-1.3	-0.0	-0.2	-1.5	-0.3	-1.6	-1.3	-1.3	-1.5	-1.5	-1.0	-1.2	-1.1	-1.3	-1.5	-1.4	-1.0	-1.3	-0.6
Emphysema/chronic bronchitis	0.6	0.7	3.0	0.2	0.1	-0.6	-0.5	-0.6	-1.7	-0.9	-0.6	-1.6	-0.8	-0.6	-0.7	-1.1	-0.6	-0.8	-0.7	-0.5	-0.6	-0.3	-0.6	-1.1	-0.7	-1.2
Medication for pain relief, constipation, heartburn	3.8	6.5	12.9	1.5	1.7	2.4	2.5	2.4	3.6	3.0	2.4	3.1	2.4	2.4	2.4	2.9	2.2	2.7	2.5	2.1	2.4	2.1	2.4	3.1	2.3	3.2
Neck or shoulder pain in last month	5.9	8.4	13.2	-2.3	-2.8	-2.7	-2.7	-2.9	-3.5	-3.6	-2.8	-3.1	-3.0	-2.9	-2.8	-2.8	-2.3	-3.1	-2.8	-2.5	-2.7	-2.7	-2.8	-3.2	-2.7	-3.5
Medication: Blood pressure	6.3	11.1	13.8	-3.4	-3.0	-3.5	-3.4	-3.5	-2.6	-2.7	-3.4	-2.9	-3.6	-3.5	-3.5	-3.7	-3.7	-3.2	-3.4	-3.2	-3.4	-3.5	-3.4	-3.4	-3.4	-3.1
Angina (self-reported)	0.4	0.5	2.3	-1.0	-1.2	-0.6	-0.3	-0.9	-0.6	-0.4	-0.2	-1.5	-0.9	-0.8	-0.6	-0.8	-0.6	-0.6	-0.7	-0.3	-0.5	-0.5	-0.5	-0.7	-0.7	-0.5
Migraine (self-reported)	0.1	0.1	0.5	-0.7	-0.6	0.0	-0.1	-0.0	-0.2	-0.1	-0.2	-0.4	-0.1	-0.1	0.1	-0.3	-0.2	-0.0	0.0	0.3	0.0	-0.3	-0.0	-0.1	0.0	-0.2
Medication: Ibuprofen	2.7	3.2	5.1	-1.1	-1.5	-1.8	-1.7	-1.8	-2.3	-1.9	-1.7	-2.0	-1.9	-1.8	-1.7	-1.9	-1.6	-1.9	-1.8	-1.5	-1.7	-1.6	-1.7	-2.0	-1.8	-2.2
Medication: Allopurinol	1.3	1.7	3.1	-1.7	-1.3	-1.4	-1.4	-1.3	-0.5	-0.7	-1.5	-0.8	-1.3	-1.4	-1.4	-1.6	-1.8	-1.0	-1.3	-1.3	-1.4	-1.5	-1.4	-1.1	-1.3	-0.7
Medication: Omeprazole	7.2	8.6	10.6	-3.1	-3.3	-2.9	-3.0	-3.0	-2.4	-2.7	-3.1	-2.2	-3.0	-3.1	-2.9	-3.1	-3.1	-3.0	-2.9	-2.8	-2.9	-3.1	-2.9	-2.8	-2.9	-3.1
Medication: Seretide 50 evohaler	13.6	15.7	18.7	-3.4	-3.0	-4.2	-4.0	-4.2	-3.4	-3.4	-4.3	-2.8	-4.0	-4.3	-4.1	-4.1	-3.9	-4.1	-4.3	-4.1	-4.2	-4.0	-4.2	-4.2	-4.3	-4.0
Mean time to correctly identify matches	6.0	11.5	15.8	3.8	3.4	3.8	3.8	3.8	1.2	2.2	3.8	0.9	3.7	3.8	3.7	3.3	3.5	3.2	3.6	3.7	3.7	4.0	3.7	3.0	3.8	2.4
Heart disease (mother)	0.3	0.3	1.4	1.2	0.8	0.5	0.6	0.5	-0.2	0.3	0.6	-0.3	0.4	0.5	0.6	0.6	0.7	0.5	0.5	0.7	0.5	0.9	0.5	0.3	0.5	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.4	0.8	1.1	0.8	0.7	0.9	1.1	1.1	0.8	0.8	0.7	0.8	0.7	0.2	0.0	1.2	0.8	1.0	0.7	0.6	0.7	1.0	0.7	1.1
Whole body fat mass	22.9	95.8	114.5	-10.7	-10.3	-10.1	-10.0	-10.5	-7.1	-8.0	-10.0	-7.5	-10.7	-10.5	-10.0	-9.9	-9.6	-10.1	-10.0	-9.9	-10.0	-10.5	-10.0	-9.6	-10.0	-9.1
Leg fat mass (right)	28.2	109.3	130.0	-11.2	-10.9	-10.7	-10.6	-11.2	-8.0	-8.9	-10.5	-8.7	-11.4	-11.2	-10.6	-10.6	-10.2	-10.8	-10.6	-10.4	-10.6	-11.0	-10.6	-10.3	-10.7	-10.0
Arm predicted mass (right)	14.5	74.1	90.6	-9.3	-8.9	-8.5	-8.4	-9.1	-7.9	-8.4	-8.0	-9.3	-9.5	-9.1	-8.3	-8.5	-7.8	-8.9	-8.6	-7.9	-8.4	-8.4	-8.3	-8.8	-8.5	-8.9
Pulse rate, automated reading	7.9	25.6	45.2	-6.5	-4.9	-5.6	-5.6	-5.4	1.7	-1.3	-6.3	1.4	-5.0	-5.6	-5.6	-5.3	-6.6	-3.8	-5.2	-5.5	-5.6	-6.7	-5.7	-3.2	-5.6	-1.5
Alcohol intake frequency.	10.1	23.6	36.5	-6.0	-5.7	-5.0	-5.1	-5.3	-2.3	-3.9	-5.3	-2.7	-5.3	-5.4	-5.0	-4.8	-5.1	-4.6	-4.8	-4.7	-5.0	-5.7	-5.0	-4.3	-4.9	-4.0
Comparative height size at age 10	0.8	4.7	8.6	2.1	2.8	1.8	1.9	2.1	2.7	2.2	1.7	2.9	2.3	2.1	1.8	2.2	2.1	2.3	2.0	1.7	1.9	1.9	1.8	2.2	1.9	2.6
Number of full sisters	4.3	5.2	9.5	-2.9	-2.8	-1.9	-2.2	-2.2	-2.4	-2.4	-2.0	-3.1	-2.2	-2.1	-2.0	-2.6	-2.3	-2.2	-2.0	-1.6	-2.0	-2.3	-2.0	-2.1	-2.0	-2.5
Suffer from ‘nerves’	0.1	0.2	0.4	-0.3	-0.4	-0.4	-0.5	-0.5	-0.6	-0.5	-0.6	-0.4	-0.1	-0.5	-0.3	-0.2	0.1	-0.4	-0.5	-0.4	-0.4	-0.2	-0.3	-0.4	-0.4	-0.3
Overall health rating	26.1	56.2	65.5	-6.7	-7.0	-7.6	-7.6	-7.7	-7.3	-7.6	-7.8	-6.1	-7.5	-7.8	-7.7	-7.4	-6.7	-8.0	-7.7	-7.4	-7.6	-7.4	-7.6	-8.0	-7.6	-8.1
Chest pain or discomfort	4.7	6.7	15.7	-2.3	-3.0	-2.2	-2.2	-2.5	-4.0	-2.8	-2.1	-3.7	-2.4	-2.5	-2.2	-2.0	-1.2	-3.2	-2.4	-2.2	-2.2	-1.9	-2.1	-3.0	-2.2	-3.6
Had major operations	5.2	6.1	13.2	-1.0	-0.9	-2.4	-2.4	-2.4	-3.6	-3.2	-2.4	-2.5	-2.1	-2.4	-2.5	-2.3	-1.8	-2.8	-2.5	-2.3	-2.4	-2.0	-2.4	-3.0	-2.4	-3.4
Age at last live birth	30.5	44.3	60.1	7.2	7.7	6.5	6.4	6.9	6.0	6.8	6.1	6.7	7.0	6.8	6.4	6.8	6.4	6.8	6.5	6.1	6.4	6.6	6.4	6.9	6.4	7.0
Family relationship satisfaction	2.1	2.6	6.9	-1.3	-1.5	-1.4	-1.5	-1.4	-2.5	-2.5	-1.2	-2.6	-1.2	-1.3	-1.4	-1.6	-1.3	-1.6	-1.5	-1.3	-1.4	-1.0	-1.3	-1.8	-1.4	-2.0
Leg pain on walking	18.3	22.9	27.8	-4.9	-5.2	-4.8	-4.7	-5.0	-3.8	-4.8	-4.7	-3.8	-5.3	-5.0	-4.8	-4.7	-4.8	-4.9	-4.9	-4.5	-4.8	-5.1	-4.8	-4.7	-4.9	-5.0
Qualifications: NVQ or HND or HNC or equivalent	8.7	10.5	22.2	-4.6	-4.7	-3.3	-3.2	-3.6	-1.3	-2.0	-3.2	-2.0	-3.7	-3.6	-3.1	-3.1	-3.3	-3.1	-3.2	-3.2	-3.1	-3.7	-3.1	-2.8	-3.3	-2.4
Commuting to job workplace: Car/motor vehicle	2.5	2.9	4.6	-1.4	-1.6	-1.7	-1.5	-1.8	-1.7	-1.6	-1.6	-1.5	-1.9	-1.9	-1.6	-1.6	-1.5	-1.9	-1.8	-1.5	-1.6	-1.8	-1.7	-1.8	-1.7	-2.2
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.8	0.1	-0.0	0.7	0.6	0.8	0.9	0.8	0.7	0.6	0.7	0.8	0.7	0.6	0.5	0.7	0.8	0.5	0.7	0.6	0.7	0.7	0.8	0.8
Medication: Aspirin	0.4	0.6	1.8	-0.7	0.2	-0.9	-0.7	-0.8	-0.1	-0.3	-0.7	-1.0	-0.8	-0.8	-0.8	-1.3	-1.4	-0.3	-0.7	-0.4	-0.8	-0.8	-0.8	-0.8	-0.8	-0.2
Supplements: Vitamin C	0.1	0.2	1.3	1.0	1.1	0.1	0.2	0.3	-0.4	-0.3	0.2	0.3	0.3	0.3	0.2	0.4	0.7	-0.0	0.1	0.1	0.1	0.4	0.1	-0.1	0.1	-0.0
Knee pain experienced in last month	6.5	10.1	18.1	-3.5	-4.2	-3.0	-2.9	-3.4	-3.2	-3.1	-2.9	-3.1	-3.7	-3.4	-2.9	-2.7	-2.4	-3.4	-3.1	-2.7	-2.9	-3.2	-3.0	-3.3	-3.1	-3.6
Hypertension (Self-reported)	0.8	2.2	5.3	-1.5	-1.1	-1.5	-1.4	-1.4	-1.7	-1.1	-1.3	-2.3	-1.4	-1.4	-1.5	-1.9	-1.8	-1.2	-1.4	-0.9	-1.5	-1.4	-1.4	-1.7	-1.4	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	5.0	5.9	7.5	-2.3	-2.4	-2.5	-2.5	-2.5	-2.0	-2.2	-2.5	-1.6	-2.4	-2.5	-2.4	-2.7	-2.7	-2.4	-2.5	-2.4	-2.5	-2.5	-2.5	-2.4	-2.5	-2.5
Illnesses of father: Heart disease	0.2	0.2	1.7	-0.5	-0.4	-0.3	-0.3	-0.4	-0.6	-1.0	-0.1	-1.3	-0.5	-0.3	-0.2	-0.5	-0.3	-0.3	-0.4	-0.1	-0.3	-0.2	-0.3	-0.4	-0.3	-0.5
Illnesses of siblings: Diabetes	3.6	4.5	13.0	-3.3	-3.6	-1.8	-1.8	-2.1	-1.7	-1.8	-1.9	-2.4	-2.0	-2.2	-1.7	-2.1	-2.0	-2.0	-1.8	-1.5	-1.8	-2.1	-1.8	-2.0	-1.8	-2.1
Smoking status: Previous	1.1	1.6	8.1	0.1	-0.7	-0.9	-0.9	-0.8	-2.8	-1.4	-0.5	-2.3	-1.4	-0.7	-1.0	-1.0	-0.5	-1.4	-1.0	-0.8	-0.9	-0.4	-0.9	-1.7	-0.9	-2.0
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	1.0	-0.0	-0.6	0.3	0.4	0.3	0.4	-0.2	0.2	0.8	0.3	0.2	0.4	0.8	1.0	0.4	0.2	0.4	0.4	0.4	0.5	0.4	0.2	0.4
Whole body fat-free mass	10.0	57.2	72.1	-8.2	-7.8	-7.4	-7.3	-8.0	-7.1	-7.5	-7.0	-8.5	-8.5	-8.0	-7.3	-7.4	-6.7	-7.8	-7.5	-6.9	-7.3	-7.3	-7.2	-7.8	-7.5	-7.9
Leg fat-free mass (right)	9.4	50.2	65.3	-7.9	-7.6	-7.0	-6.9	-7.5	-6.1	-6.7	-6.6	-7.5	-8.1	-7.5	-6.9	-6.9	-6.4	-7.3	-7.1	-6.7	-6.9	-7.0	-6.8	-7.1	-7.0	-7.1
Arm fat percentage (left)	18.2	72.8	88.3	-9.3	-9.2	-8.8	-8.8	-9.2	-5.7	-6.6	-8.8	-6.1	-9.4	-9.2	-8.8	-8.6	-8.5	-8.8	-8.7	-8.9	-8.8	-9.2	-8.8	-8.2	-8.8	-7.7
Average weekly red wine intake	3.9	5.8	10.7	3.2	3.2	2.1	2.2	2.5	2.6	2.5	2.0	3.3	2.3	2.5	2.0	2.3	1.9	2.6	2.2	2.0	2.1	2.2	1.9	2.4	2.1	2.8
Handedness (chirality/laterality): Left-handed	0.2	0.3	2.0	0.6	1.4	0.4	0.4	0.5	0.3	0.2	0.6	-0.2	0.6	0.5	0.4	0.3	0.2	0.7	0.4	0.4	0.4	0.6	0.6	0.3	0.4	0.6
Mood swings	16.3	29.4	35.5	-5.0	-5.5	-5.4	-5.6	-5.6	-5.1	-6.0	-5.4	-5.1	-5.4	-5.6	-5.4	-5.7	-5.0	-5.5	-5.6	-5.2	-5.5	-5.1	-5.4	-5.5	-5.5	-5.4
Loneliness, isolation	7.9	10.9	13.5	-2.6	-2.9	-3.4	-3.4	-3.5	-3.4	-3.4	-3.3	-2.6	-3.4	-3.5	-3.3	-3.3	-2.9	-3.6	-3.5	-3.2	-3.4	-3.3	-3.3	-3.7	-3.5	-3.7
Long-standing illness, disability or infirmity	5.6	8.6	16.4	-3.6	-3.2	-2.7	-2.6	-2.9	-2.8	-3.0	-2.7	-4.0	-3.0	-3.0	-2.7	-3.3	-3.0	-2.6	-2.8	-2.1	-2.7	-2.7	-2.7	-2.9	-2.7	-3.0
Ever had bowel cancer screening	13.9	16.2	20.6	4.3	3.7	4.2	4.4	4.2	2.4	3.5	4.5	2.0	4.1	4.2	4.3	4.4	4.5	3.9	4.1	4.3	4.3	4.5	4.4	3.8	4.2	3.4
Diabetes diagnosed by doctor	10.0	16.4	27.4	-5.2	-3.9	-4.1	-4.0	-4.3	-2.1	-2.9	-4.2	-3.8	-4.3	-4.4	-4.1	-5.0	-5.2	-3.4	-4.0	-3.5	-4.1	-4.5	-4.1	-3.7	-4.1	-3.0
Ever had stillbirth, spontaneous miscarriage or termination	2.9	3.1	5.6	-1.5	-1.6	-1.8	-1.8	-1.8	-1.7	-1.9	-1.6	-2.4	-2.0	-1.8	-1.8	-2.0	-1.8	-1.5	-1.9	-1.7	-1.8	-1.4	-1.6	-1.9	-1.9	-1.5
Friendships satisfaction	1.9	2.4	4.8	2.2	1.7	1.6	1.5	1.7	0.4	0.5	1.5	0.8	2.1	1.8	1.5	1.6	1.7	1.6	1.5	1.6	1.5	2.0	1.6	1.2	1.6	1.2
Qualifications: nursing, teaching	12.4	19.3	26.7	4.0	3.4	4.8	4.6	4.8	2.7	3.2	4.9	1.7	4.8	4.8	4.7	4.5	4.6	4.6	4.7	4.7	4.7	5.2	4.8	4.3	4.8	4.1
Commuting to job workplace: Walk	3.7	4.0	5.9	2.3	2.4	1.8	1.9	1.9	2.0	1.7	1.9	1.9	2.0	1.9	1.9	2.0	2.1	2.2	1.8	2.0	1.9	2.0	2.0	1.9	1.8	2.4
Eye problems/disorders: Cataract	0.3	0.3	1.7	0.9	1.3	0.4	0.4	0.5	0.5	-0.0	0.3	0.6	0.8	0.5	0.4	-0.3	-0.3	0.6	0.4	0.7	0.4	0.3	0.3	0.5	0.4	0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	3.5	-1.9	-1.7	0.2	0.2	-0.2	0.0	0.5	0.4	-1.3	-0.3	-0.2	0.2	-0.2	-0.2	-0.2	0.2	0.4	0.2	-0.3	0.2	0.0	0.2	-0.3
Medication for cholesterol	1.9	2.9	4.7	2.2	1.7	1.8	1.7	1.9	1.0	1.3	1.7	1.4	1.9	1.9	1.7	1.7	1.8	1.6	1.8	1.5	1.7	1.9	1.7	1.6	1.8	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.0	3.5	5.5	-1.2	-0.9	-1.9	-1.9	-1.9	-2.4	-2.3	-1.8	-2.0	-1.5	-1.9	-1.9	-2.1	-1.8	-1.9	-1.9	-1.7	-1.9	-1.7	-1.8	-2.1	-1.9	-2.2
Back pain experienced in last month	3.7	5.4	6.5	-1.9	-2.3	-2.4	-2.5	-2.5	-2.3	-2.5	-2.3	-1.5	-2.5	-2.4	-2.2	-2.2	-1.9	-2.5	-2.5	-2.3	-2.4	-2.2	-2.4	-2.4	-2.5	-2.5
Mineral and other dietary supplements	0.4	0.5	1.8	-1.3	-1.0	-0.7	-0.7	-0.7	0.1	-0.1	-0.8	-0.4	-0.6	-0.7	-0.6	-0.8	-0.9	-0.5	-0.6	-0.7	-0.7	-0.9	-0.6	-0.4	-0.7	-0.2
Breast cancer (self-reported)	1.3	1.6	4.2	-1.3	-2.1	-1.1	-1.0	-1.2	-1.5	-1.5	-0.9	-1.7	-1.7	-1.2	-1.1	-0.6	-0.4	-1.4	-1.1	-1.1	-1.1	-0.9	-1.1	-1.3	-1.1	-1.6
Asthma (self-reported)	5.6	11.2	18.4	-4.2	-4.3	-3.1	-3.1	-3.3	-3.2	-3.2	-3.2	-3.8	-3.5	-3.4	-3.1	-3.0	-2.7	-3.6	-3.1	-3.1	-3.1	-3.1	-3.2	-3.4	-3.1	-3.7
Osteoporosis (self-reported)	0.7	0.9	3.4	0.3	-0.4	0.9	0.9	0.7	-1.4	-0.8	1.2	-1.8	0.5	0.8	0.9	1.1	1.7	0.0	0.7	0.6	0.9	1.3	1.1	0.1	0.9	-0.5
Osteoarthritis (self-reported)	7.2	9.4	12.2	-3.2	-3.5	-3.1	-3.0	-3.3	-2.5	-2.9	-3.1	-2.1	-3.2	-3.4	-3.0	-2.8	-2.8	-3.2	-3.1	-2.9	-3.1	-3.3	-3.2	-3.1	-3.1	-3.2
Medication: Aspirin	0.4	0.6	1.6	-0.6	0.4	-0.8	-0.7	-0.7	-0.5	-0.4	-0.7	-1.3	-0.7	-0.7	-0.8	-1.3	-1.3	-0.4	-0.7	-0.4	-0.8	-0.7	-0.7	-0.9	-0.7	-0.4
Medication: Gliclazide	3.5	4.0	6.7	-2.6	-2.0	-2.1	-2.0	-2.1	-1.1	-1.7	-2.1	-1.9	-1.9	-2.1	-2.1	-2.3	-2.3	-1.7	-2.0	-1.8	-2.0	-2.1	-2.1	-1.9	-2.0	-1.5
Illnesses of father: None of the above (group 1)	0.1	0.2	1.8	0.5	0.3	0.1	0.2	0.3	0.7	0.3	-0.0	1.3	0.3	0.3	0.1	0.2	0.2	0.3	0.3	0.1	0.2	0.0	0.0	0.3	0.2	0.5
Smoking status: Current	3.6	5.7	8.2	-2.2	-2.3	-2.3	-2.4	-2.4	-2.7	-2.9	-2.2	-2.1	-2.4	-2.4	-2.3	-2.3	-1.9	-2.8	-2.3	-2.5	-2.3	-2.4	-2.3	-2.5	-2.3	-2.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	7.2	15.2	25.8	2.5	2.3	3.9	4.0	3.8	5.1	4.6	3.7	3.7	3.5	3.8	4.0	4.0	3.3	4.3	4.0	3.9	4.0	3.4	4.0	4.6	3.9	4.7
Whole body water mass	10.3	59.0	73.8	-8.4	-8.0	-7.5	-7.4	-8.1	-7.2	-7.6	-7.1	-8.6	-8.6	-8.1	-7.4	-7.5	-6.8	-7.9	-7.6	-7.0	-7.4	-7.5	-7.3	-7.9	-7.6	-8.0
Leg predicted mass (right)	9.2	49.3	64.4	-7.9	-7.5	-6.9	-6.9	-7.5	-6.0	-6.6	-6.5	-7.4	-8.0	-7.5	-6.8	-6.8	-6.4	-7.3	-7.0	-6.6	-6.8	-7.0	-6.7	-7.0	-7.0	-7.0
Arm fat mass (left)	24.0	98.6	121.0	-10.8	-10.5	-10.1	-10.1	-10.7	-7.4	-8.2	-9.9	-8.1	-11.0	-10.6	-10.1	-10.0	-9.7	-10.2	-10.1	-10.0	-10.1	-10.5	-10.1	-9.7	-10.1	-9.4
Number of self-reported non-cancer illnesses	6.3	11.0	14.9	-3.6	-3.5	-3.2	-3.1	-3.3	-3.5	-3.3	-3.3	-3.4	-3.1	-3.4	-3.2	-3.3	-2.9	-3.5	-3.3	-2.9	-3.2	-3.2	-3.2	-3.6	-3.2	-3.9
Average weekly champagne plus white wine intake	5.2	7.1	10.9	2.9	2.2	2.8	2.9	2.9	1.4	2.0	3.0	0.9	2.8	2.9	2.9	2.6	2.8	2.8	2.8	2.8	2.9	3.3	3.0	2.4	2.8	2.3
Miserableness	19.6	33.9	42.8	-5.2	-5.7	-5.7	-5.8	-5.9	-6.3	-6.4	-5.7	-5.7	-5.6	-5.9	-5.7	-5.8	-4.9	-6.3	-5.9	-5.6	-5.8	-5.4	-5.7	-6.2	-5.7	-6.5
Guilty feelings	8.8	13.3	17.4	-2.4	-2.3	-3.8	-3.9	-3.7	-4.1	-4.0	-3.7	-3.0	-3.5	-3.7	-3.8	-3.6	-3.1	-4.0	-3.9	-3.8	-3.8	-3.4	-3.8	-4.1	-3.8	-4.2
Wears glasses or contact lenses	1.2	1.3	1.9	-1.2	-0.5	-1.0	-1.2	-1.0	-1.2	-1.0	-1.3	-1.4	-1.0	-1.0	-1.2	-1.3	-1.2	-1.3	-1.0	-1.3	-1.2	-1.2	-1.3	-1.1	-1.0	-1.4
Ever taken oral contraceptive pill	1.2	1.3	4.8	-0.7	-1.7	-0.8	-0.8	-0.9	-2.0	-1.7	-0.5	-2.2	-1.3	-0.9	-0.8	-0.9	-0.5	-1.1	-1.0	-0.8	-0.8	-0.4	-0.7	-1.4	-0.9	-1.5
Hearing aid user	0.2	0.2	1.0	-1.0	-0.4	-0.4	-0.4	-0.5	0.1	-0.2	-0.4	-0.5	-0.4	-0.5	-0.4	-0.7	-0.7	-0.3	-0.4	-0.4	-0.4	-0.7	-0.5	-0.2	-0.4	-0.2
Mother’s age at death	6.1	7.7	13.4	2.3	2.3	2.6	2.7	2.7	3.6	3.5	2.3	3.7	2.8	2.6	2.6	2.9	2.4	2.8	2.6	2.5	2.6	2.2	2.4	3.1	2.5	3.2
Financial situation satisfaction	13.7	17.0	22.1	-3.4	-3.6	-4.3	-4.1	-4.3	-4.0	-4.7	-4.1	-4.0	-4.2	-4.3	-4.2	-4.2	-3.8	-4.1	-4.3	-3.9	-4.2	-3.8	-4.2	-4.4	-4.3	-4.1
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.2	-0.5	-0.1	-0.6	-0.7	-0.6	0.6	-0.0	-0.7	0.6	-0.6	-0.6	-0.6	-0.7	-1.1	-0.2	-0.6	-0.5	-0.7	-0.8	-0.7	-0.2	-0.7	-0.0
Commuting to job workplace: Public transport	4.3	5.1	7.1	2.1	2.4	2.2	2.2	2.2	2.3	2.3	2.2	2.2	2.3	2.2	2.2	2.7	2.4	2.2	2.2	1.9	2.2	2.1	2.2	2.5	2.2	2.4
Eye problems/disorders: Glaucoma	0.2	0.2	1.2	-1.0	-0.8	0.1	0.1	-0.2	0.5	0.0	0.3	-1.1	0.0	-0.2	0.2	-0.3	-0.4	0.4	0.1	0.5	0.1	0.0	0.2	0.2	0.1	0.5
Medication: Blood pressure	0.4	0.7	1.6	-1.2	-0.7	-0.8	-0.9	-0.9	-0.5	-0.4	-0.9	-1.3	-0.8	-0.9	-0.8	-1.1	-1.2	-0.5	-0.9	-0.4	-0.8	-0.9	-0.8	-0.7	-0.9	-0.6
Pain type(s) experienced in last month: Hip pain	4.4	5.6	7.6	-2.4	-2.5	-2.3	-2.2	-2.4	-2.2	-2.6	-2.2	-2.3	-2.8	-2.4	-2.2	-2.3	-2.2	-2.5	-2.3	-2.1	-2.2	-2.3	-2.3	-2.4	-2.3	-2.6
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.3	1.1	1.0	0.6	0.7	0.7	0.8	0.8	0.7	0.9	0.4	0.7	0.6	0.6	0.5	0.9	0.6	0.7	0.6	0.7	0.6	0.7	0.6	0.9
High cholesterol (Self-reported)	0.1	0.2	1.3	-0.4	0.1	-0.3	-0.1	-0.3	1.1	1.1	-0.2	0.4	-0.5	-0.2	-0.3	-0.2	-0.5	0.2	-0.2	-0.1	-0.2	-0.4	-0.3	0.2	-0.2	0.6
Medication: Bendroflumethiazide	1.0	1.5	2.5	-1.6	-1.5	-1.2	-1.3	-1.3	-0.9	-0.7	-1.3	-1.5	-1.4	-1.3	-1.3	-1.3	-1.2	-1.1	-1.1	-1.0	-1.2	-1.3	-1.1	-1.2	-1.1	-1.0
Medication: Paracetamol	6.4	9.9	22.2	-1.3	-2.2	-3.0	-3.0	-3.0	-4.7	-4.3	-3.0	-3.0	-3.0	-3.0	-2.9	-2.8	-1.9	-3.7	-3.2	-3.0	-3.0	-2.5	-3.0	-3.8	-3.0	-4.3
Medication: Lisinopril	0.7	0.9	1.6	-1.3	-0.8	-1.0	-1.0	-1.0	-0.5	-0.5	-1.2	-0.9	-0.9	-1.0	-1.1	-1.0	-1.1	-0.8	-0.9	-0.8	-1.0	-1.1	-1.1	-0.9	-0.9	-0.8
Medication: Atorvastatin	0.3	0.3	1.2	-0.9	-0.5	-0.4	-0.3	-0.6	-0.2	0.1	-0.4	-1.1	-0.6	-0.6	-0.4	-0.8	-1.0	-0.3	-0.4	-0.1	-0.4	-0.7	-0.4	-0.3	-0.4	-0.5
Illnesses of father: High blood pressure	0.2	0.2	1.4	-0.8	-0.3	-0.3	-0.5	-0.3	0.3	0.5	-0.6	-0.3	-0.2	-0.3	-0.5	-0.9	-1.2	0.2	-0.2	-0.1	-0.5	-0.5	-0.5	-0.0	-0.3	0.1
Alcohol drinker status: Never	0.7	0.8	5.3	-0.3	0.1	0.6	0.5	0.6	2.3	1.4	0.2	1.6	0.6	0.5	0.6	0.4	-0.1	1.1	0.7	0.6	0.6	0.0	0.6	1.3	0.6	1.6
Ever smoked	0.7	1.2	9.9	0.5	-0.5	-0.2	-0.4	-0.2	-3.1	-1.9	0.0	-2.2	-0.6	-0.1	-0.4	-0.3	0.4	-1.2	-0.4	-0.5	-0.3	0.2	-0.3	-1.2	-0.2	-2.0
Basal metabolic rate	13.1	72.5	89.7	-9.3	-8.8	-8.4	-8.4	-9.0	-7.5	-8.1	-8.1	-8.8	-9.5	-9.0	-8.3	-8.4	-7.8	-8.8	-8.5	-8.0	-8.3	-8.5	-8.3	-8.6	-8.5	-8.7
Leg fat percentage (left)	24.4	88.4	104.0	-10.1	-9.8	-9.7	-9.7	-10.2	-6.8	-7.6	-9.6	-7.2	-10.1	-10.2	-9.7	-9.7	-9.4	-9.6	-9.7	-9.4	-9.7	-10.1	-9.7	-9.1	-9.7	-8.7
Arm fat-free mass (left)	15.4	77.9	93.7	-9.5	-9.0	-8.7	-8.7	-9.3	-8.1	-8.6	-8.2	-9.4	-9.7	-9.3	-8.6	-8.8	-8.1	-9.1	-8.8	-8.1	-8.6	-8.7	-8.5	-9.0	-8.7	-9.1
Number of operations (self-reported)	6.7	9.9	18.3	-2.9	-3.8	-2.8	-2.7	-3.1	-4.3	-4.0	-2.6	-3.8	-3.3	-3.1	-2.7	-2.5	-1.9	-3.5	-3.0	-2.6	-2.7	-2.5	-2.7	-3.5	-2.9	-4.1
Average weekly beer plus cider intake	20.4	29.6	33.6	-5.6	-5.7	-5.4	-5.5	-5.6	-5.0	-5.5	-5.3	-4.5	-5.7	-5.5	-5.3	-5.4	-5.2	-5.8	-5.4	-5.5	-5.4	-5.5	-5.4	-5.5	-5.4	-5.8
Irritability	1.8	3.1	11.9	-0.7	-1.1	-1.2	-1.5	-1.3	-3.5	-2.9	-1.2	-3.4	-1.2	-1.3	-1.3	-1.9	-1.1	-1.5	-1.5	-1.0	-1.3	-0.7	-1.1	-1.9	-1.3	-2.4
Risk taking	1.2	1.8	5.3	-2.1	-2.3	-1.1	-1.1	-1.3	-1.1	-1.5	-0.8	-1.7	-1.5	-1.3	-1.1	-1.2	-1.3	-1.2	-1.1	-1.0	-1.1	-1.3	-1.0	-1.1	-1.0	-1.2
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.2	0.5	0.3	0.4	0.5	0.4	0.8	1.1	0.2	1.1	0.4	0.3	0.5	0.6	0.5	0.4	0.4	0.3	0.4	0.4	0.4	0.5	0.3	0.5
Fractured/broken bones in last 5 years	1.1	1.5	2.3	1.2	1.2	1.4	1.3	1.3	-0.2	0.3	1.4	-0.4	1.3	1.4	1.4	1.2	1.5	0.9	1.3	1.4	1.3	1.5	1.3	0.9	1.4	0.4
Age started oral contraceptive pill	10.6	13.3	15.9	3.7	3.9	3.8	3.7	3.9	2.9	3.1	3.6	3.2	4.0	3.8	3.8	4.0	3.7	3.5	3.7	3.5	3.7	3.6	3.7	3.7	3.7	3.3
Diastolic blood pressure, automated reading	11.6	35.9	47.2	-5.8	-4.9	-6.5	-6.6	-6.4	-3.3	-4.7	-6.7	-2.8	-6.4	-6.4	-6.5	-6.5	-6.8	-5.7	-6.3	-6.2	-6.5	-6.9	-6.6	-5.6	-6.4	-5.0
Ever depressed for a whole week	5.4	6.7	18.6	-2.1	-2.4	-2.1	-2.1	-2.2	-4.3	-3.5	-2.1	-4.3	-2.0	-2.2	-2.1	-2.3	-1.5	-2.8	-2.2	-1.9	-2.1	-1.8	-2.1	-3.0	-2.1	-3.6
Unable to work because of sickness or disability	0.5	0.7	2.1	-1.0	-1.5	-0.7	-0.7	-0.8	-1.1	-0.8	-0.7	-1.3	-0.8	-0.8	-0.7	-0.6	-0.2	-0.9	-0.7	-0.6	-0.7	-0.5	-0.7	-0.9	-0.7	-1.0
Commuting to job workplace: Cycle	1.7	2.0	3.4	1.2	1.5	1.4	1.3	1.6	1.7	1.1	1.2	1.0	1.6	1.6	1.3	1.3	1.0	1.7	1.5	1.2	1.3	1.5	1.3	1.6	1.5	1.8
Myopia	4.6	6.7	11.1	1.5	0.6	2.9	2.8	2.7	1.9	2.7	2.8	1.4	2.5	2.6	2.9	3.3	3.3	2.2	2.8	2.5	2.9	2.7	2.9	2.6	2.9	2.1
Vascular/heart problems diagnosed by doctor	2.2	5.9	9.2	2.3	1.8	2.6	2.4	2.5	2.2	1.9	2.4	2.7	2.5	2.5	2.6	3.0	2.9	2.1	2.5	1.9	2.5	2.5	2.5	2.7	2.5	2.3
Cholesterol lowering medication	1.1	1.7	6.8	-2.1	-1.7	-1.0	-1.1	-1.3	-0.9	-0.8	-0.9	-2.6	-1.4	-1.3	-1.0	-1.5	-1.5	-1.0	-1.0	-0.8	-1.0	-1.1	-0.9	-1.0	-1.0	-1.0
Medication: Omeprazole (e.g. Zanprol)	3.2	3.9	8.4	-2.4	-2.9	-1.8	-1.9	-1.9	-1.8	-1.8	-2.0	-1.9	-1.9	-2.0	-1.8	-1.9	-1.8	-2.0	-1.8	-1.7	-1.8	-2.0	-1.8	-1.9	-1.8	-2.2
Pain experienced in last month	12.3	20.5	26.7	3.8	4.1	4.4	4.6	4.7	4.8	4.8	4.5	3.9	4.8	4.6	4.5	4.4	3.9	5.0	4.6	4.4	4.5	4.5	4.5	4.7	4.5	5.2
Supplements: Calcium	3.8	4.2	7.7	2.1	1.4	2.3	2.2	2.2	0.1	1.0	2.5	-0.1	2.2	2.3	2.3	2.5	2.8	1.6	2.2	2.2	2.3	2.6	2.3	1.6	2.4	1.1
Basal cell carcinoma (self-reported)	6.9	8.2	10.0	2.7	2.6	3.1	2.9	3.0	2.1	2.8	3.1	1.5	2.9	3.1	3.1	2.9	2.8	2.9	3.1	2.9	3.1	3.1	3.2	2.8	3.1	2.7
Heart attack/myocardial infarction (self-reported)	4.2	5.4	7.9	-2.1	-2.2	-2.4	-2.4	-2.4	-1.7	-2.2	-2.3	-1.6	-2.6	-2.4	-2.5	-2.8	-2.8	-2.1	-2.3	-2.1	-2.4	-2.5	-2.4	-2.3	-2.3	-2.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.1	-1.4	-1.5	-0.4	-0.7	-0.6	-0.7	-0.6	-0.6	-0.8	-0.5	-0.6	-0.4	-0.4	-0.4	-0.7	-0.4	-0.4	-0.4	-0.7	-0.4	-0.5	-0.4	-0.8
Heart disease (siblings)	0.1	0.1	0.2	0.1	-0.2	-0.3	-0.1	-0.4	-0.5	-0.4	-0.1	-0.5	-0.2	-0.4	-0.2	-0.2	-0.1	-0.3	-0.3	-0.0	-0.2	-0.1	-0.1	-0.4	-0.3	-0.3
Alcohol drinker status: Previous	4.1	4.7	8.6	-1.5	-1.8	-2.0	-2.2	-2.2	-2.8	-2.8	-1.8	-2.9	-2.5	-2.1	-2.1	-1.9	-1.6	-2.2	-2.2	-2.0	-2.1	-1.7	-2.0	-2.3	-2.1	-2.5
Pack years of smoking	2.3	3.4	8.8	-0.7	-0.9	-1.7	-1.7	-1.8	-2.9	-2.4	-1.5	-3.0	-2.0	-1.7	-1.7	-1.9	-1.3	-1.9	-1.8	-1.5	-1.7	-1.3	-1.6	-2.2	-1.7	-2.2
Impedance of whole body	12.8	65.4	132.2	7.9	8.1	7.4	7.3	8.2	9.3	8.8	6.5	11.5	9.2	8.2	7.3	7.9	6.8	8.4	7.7	6.8	7.3	7.1	7.1	8.6	7.5	9.2
Leg fat mass (left)	28.6	111.5	132.2	-11.4	-11.0	-10.8	-10.7	-11.4	-8.1	-9.0	-10.6	-8.8	-11.5	-11.3	-10.7	-10.8	-10.4	-10.8	-10.7	-10.5	-10.7	-11.1	-10.7	-10.4	-10.8	-10.0
Arm predicted mass (left)	15.4	78.4	95.3	-9.6	-9.2	-8.7	-8.7	-9.4	-8.1	-8.5	-8.3	-9.4	-9.8	-9.3	-8.6	-8.8	-8.1	-9.1	-8.8	-8.1	-8.6	-8.8	-8.5	-9.0	-8.8	-9.1