TWAS hub - UBA7

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.0610	0.0320	3.2e-03	0.024	NA	0.014	NA	-0.003	1.8e-02	NA	5.3e-02	NA	5.4e-01
2	GTEx	Artery Tibial	0.0425	0.0292	9.9e-03	0.032	NA	0.005	NA	0.021	1.5e-03	NA	1.2e-01	NA	7.8e-03
3	GTEx	Cells Transformed fibroblasts	0.0690	0.0380	6.1e-04	0.064	NA	0.038	NA	0.007	1.4e-05	NA	7.5e-04	NA	8.7e-02
4	GTEx	Colon Transverse	0.2790	0.0730	6.8e-13	0.305	NA	0.283	NA	0.299	5.3e-15	NA	7.1e-14	NA	1.1e-14
5	GTEx	Esophagus Mucosa	0.0430	0.0210	8.9e-04	0.073	NA	0.046	NA	-0.004	1.3e-05	NA	4.5e-04	NA	9.8e-01
6	GTEx	Skin Not Sun Exposed Suprapubic	0.0660	0.0310	2.7e-04	0.034	NA	0.057	NA	0.061	5.8e-03	NA	4.7e-04	NA	2.9e-04
7	GTEx	Skin Sun Exposed Lower leg	0.0400	0.0250	5.8e-03	0.009	NA	-0.001	NA	0.000	5.8e-02	NA	4.4e-01	NA	2.9e-01
8	GTEx	Spleen	0.1900	0.0800	2.0e-04	0.135	NA	0.110	NA	0.111	2.5e-04	NA	9.5e-04	NA	8.8e-04
9	GTEx	Thyroid	0.0450	0.0240	5.1e-03	0.008	NA	0.021	NA	0.008	7.2e-02	NA	9.2e-03	NA	7.2e-02
10	GTEx	Whole Blood	0.0310	0.0180	3.7e-03	0.039	NA	0.005	NA	0.015	1.5e-04	NA	1.1e-01	NA	1.5e-02
11	NTR	Blood	0.0185	0.0083	6.3e-08	0.030	0.026	0.024	0.026	0.028	4.9e-10	5.3e-09	2.0e-08	4.8e-09	1.6e-09
12	YFS	Blood	0.1630	0.0429	0.0e+00	0.235	0.224	0.229	0.229	0.234	1.3e-75	1.1e-71	2.2e-73	1.9e-73	4.0e-75
13	TCGA	Breast Invasive Carcinoma	0.0134	0.0084	2.9e-04	0.014	0.005	0.014	NA	-0.001	5.6e-04	2.7e-02	6.6e-04	NA	8.4e-01
14	TCGA	Colon Adenocarcinoma	0.1100	0.0660	2.5e-06	0.063	0.022	0.049	NA	0.016	1.7e-04	1.9e-02	7.6e-04	NA	3.8e-02
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.0189	0.0131	4.5e-03	0.021	0.018	0.009	NA	0.013	1.7e-03	3.8e-03	3.0e-02	NA	1.1e-02
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0790	0.0400	1.7e-09	0.092	0.086	0.084	NA	0.089	1.4e-10	6.4e-10	1.1e-09	NA	3.4e-10
17	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1340	0.0680	2.3e-08	0.162	0.139	0.144	NA	0.146	1.5e-09	2.4e-08	1.3e-08	NA	1.1e-08
18	TCGA	Lung Adenocarcinoma	0.0334	0.0198	3.4e-05	0.041	0.007	0.020	NA	-0.001	1.2e-05	4.0e-02	1.8e-03	NA	3.8e-01
19	TCGA	Lung Squamous Cell Carcinoma	0.0170	0.0115	3.3e-03	0.014	0.016	0.016	NA	0.010	9.5e-03	5.3e-03	5.9e-03	NA	2.3e-02
20	TCGA	Pancreatic Adenocarcinoma	0.1110	0.0800	6.4e-05	0.143	0.089	0.109	NA	-0.002	1.4e-06	1.5e-04	2.7e-05	NA	4.1e-01
21	TCGA	Prostate Adenocarcinoma	0.0494	0.0298	3.7e-06	0.043	0.036	0.045	NA	0.038	2.6e-05	1.0e-04	1.6e-05	NA	7.6e-05
22	TCGA	Stomach Adenocarcinoma	0.0400	0.0260	1.1e-03	0.048	0.033	0.034	NA	0.037	2.0e-04	1.9e-03	1.7e-03	NA	1.0e-03
23	TCGA	Thyroid Carcinoma	0.0300	0.0200	1.6e-03	0.006	0.024	0.011	NA	0.015	7.6e-02	2.0e-03	2.9e-02	NA	1.1e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Qualifications: A levels/AS levels or equivalent	41.5	92.0	106.1	8.9	8.6	10.0	10.0	10.3	7.9	8.7	9.7	6.8	10.2	10.2	9.9	9.7	9.4	10.2	10.0	10.0	10.0	10.0	9.9	9.8	10.0	9.6
Qualifications: College or University degree	41.4	130.4	156.2	10.1	10.3	11.8	11.8	12.2	10.1	10.5	11.6	7.8	12.3	12.2	11.7	11.1	10.3	12.5	11.9	11.8	11.8	12.0	11.8	11.9	11.9	12.1
Age at First Birth	38.7	56.3	68.7	7.4	7.3	7.7	7.6	8.0	6.5	7.1	7.3	6.6	8.3	7.9	7.5	7.6	7.4	7.6	7.8	7.0	7.5	7.6	7.5	7.7	7.8	7.6
Intelligence (Savage-Jansen 2018)	34.4	105.7	125.4	9.3	9.9	10.9	10.6	11.1	8.5	9.5	10.3	6.9	11.2	11.0	10.7	9.7	9.2	11.0	10.9	10.9	10.7	10.5	10.6	10.7	10.9	10.2
Age at last live birth	30.5	44.3	60.1	7.2	7.7	6.5	6.4	6.9	6.0	6.8	6.1	6.7	7.0	6.8	6.4	6.8	6.4	6.8	6.5	6.1	6.4	6.6	6.4	6.9	6.4	7.0
Fluid intelligence score	29.3	60.8	69.5	7.5	7.2	8.2	8.1	8.3	6.5	7.0	7.9	6.1	8.2	8.3	8.1	7.8	7.5	8.0	8.2	8.1	8.1	7.9	8.0	8.0	8.2	7.5
Body mass index (BMI)	28.8	122.7	151.3	-11.8	-11.7	-11.1	-11.1	-11.8	-9.1	-9.6	-10.7	-10.4	-12.3	-11.8	-11.1	-11.3	-10.7	-11.4	-11.2	-10.8	-11.1	-11.4	-11.0	-11.0	-11.1	-10.8
Leg fat mass (left)	28.6	111.5	132.2	-11.4	-11.0	-10.8	-10.7	-11.4	-8.1	-9.0	-10.6	-8.8	-11.5	-11.3	-10.7	-10.8	-10.4	-10.8	-10.7	-10.5	-10.7	-11.1	-10.7	-10.4	-10.8	-10.0
Leg fat mass (right)	28.2	109.3	130.0	-11.2	-10.9	-10.7	-10.6	-11.2	-8.0	-8.9	-10.5	-8.7	-11.4	-11.2	-10.6	-10.6	-10.2	-10.8	-10.6	-10.4	-10.6	-11.0	-10.6	-10.3	-10.7	-10.0
Verbal and Numeric Reasoning (VNR)	28.0	67.2	76.9	7.5	7.7	8.6	8.6	8.8	7.1	7.7	8.1	5.9	8.6	8.6	8.5	8.1	7.6	8.6	8.6	8.6	8.6	8.3	8.4	8.6	8.6	8.1
Age at first live birth	28.0	49.6	57.0	7.6	7.5	7.0	7.0	7.3	6.2	7.0	6.7	6.6	7.5	7.2	6.9	7.4	7.0	7.2	6.9	6.5	7.0	7.2	7.0	7.2	6.9	7.2
Overall health rating	26.1	56.2	65.5	-6.7	-7.0	-7.6	-7.6	-7.7	-7.3	-7.6	-7.8	-6.1	-7.5	-7.8	-7.7	-7.4	-6.7	-8.0	-7.7	-7.4	-7.6	-7.4	-7.6	-8.0	-7.6	-8.1
BMI	25.4	147.4	185.0	-13.0	-12.8	-12.2	-12.1	-13.1	-10.2	-10.6	-11.5	-11.7	-13.6	-12.9	-12.0	-12.1	-11.5	-12.6	-12.3	-11.8	-12.1	-12.3	-12.0	-12.2	-12.2	-11.9
Taking other prescription medications	25.4	39.2	45.4	-6.7	-6.6	-6.2	-6.2	-6.4	-5.5	-6.3	-6.3	-5.7	-6.3	-6.4	-6.2	-6.5	-6.2	-6.5	-6.2	-6.0	-6.2	-6.3	-6.2	-6.4	-6.2	-6.4
Leg fat percentage (right)	24.5	88.8	104.0	-10.1	-9.9	-9.7	-9.7	-10.2	-6.9	-7.7	-9.7	-7.1	-10.1	-10.1	-9.7	-9.6	-9.3	-9.7	-9.7	-9.5	-9.7	-10.1	-9.7	-9.2	-9.7	-8.8
Leg fat percentage (left)	24.4	88.4	104.0	-10.1	-9.8	-9.7	-9.7	-10.2	-6.8	-7.6	-9.6	-7.2	-10.1	-10.2	-9.7	-9.7	-9.4	-9.6	-9.7	-9.4	-9.7	-10.1	-9.7	-9.1	-9.7	-8.7
Arm fat mass (left)	24.0	98.6	121.0	-10.8	-10.5	-10.1	-10.1	-10.7	-7.4	-8.2	-9.9	-8.1	-11.0	-10.6	-10.1	-10.0	-9.7	-10.2	-10.1	-10.0	-10.1	-10.5	-10.1	-9.7	-10.1	-9.4
Arm fat mass (right)	23.8	98.1	118.8	-10.8	-10.4	-10.1	-10.1	-10.7	-7.4	-8.2	-9.9	-8.0	-10.9	-10.6	-10.0	-10.0	-9.7	-10.3	-10.1	-10.0	-10.0	-10.5	-10.1	-9.7	-10.1	-9.4
Wheeze or whistling in the chest in last year	22.9	40.9	46.2	-6.7	-6.8	-6.4	-6.4	-6.7	-6.0	-6.2	-6.3	-6.1	-6.7	-6.7	-6.3	-6.1	-5.5	-6.8	-6.4	-6.4	-6.3	-6.2	-6.3	-6.6	-6.4	-6.6
Whole body fat mass	22.9	95.8	114.5	-10.7	-10.3	-10.1	-10.0	-10.5	-7.1	-8.0	-10.0	-7.5	-10.7	-10.5	-10.0	-9.9	-9.6	-10.1	-10.0	-9.9	-10.0	-10.5	-10.0	-9.6	-10.0	-9.1
Qualifications: None of the above	21.2	45.3	55.2	-5.6	-5.2	-6.8	-6.9	-7.0	-6.8	-6.6	-6.8	-5.6	-6.9	-7.0	-7.0	-6.8	-6.2	-7.4	-6.9	-6.8	-6.9	-6.9	-7.0	-7.1	-6.8	-7.4
Number of treatments/medications taken	21.0	37.8	42.3	-6.1	-5.6	-6.2	-6.2	-6.4	-5.6	-5.9	-6.3	-5.5	-6.2	-6.4	-6.2	-6.5	-6.1	-6.4	-6.2	-5.9	-6.2	-6.2	-6.1	-6.5	-6.2	-6.4
Weight	20.4	100.2	123.2	-11.0	-10.6	-10.1	-10.0	-10.7	-8.0	-8.8	-9.8	-9.2	-11.1	-10.7	-10.0	-10.0	-9.6	-10.3	-10.1	-9.7	-10.0	-10.3	-10.0	-9.9	-10.1	-9.7
Average weekly beer plus cider intake	20.4	29.6	33.6	-5.6	-5.7	-5.4	-5.5	-5.6	-5.0	-5.5	-5.3	-4.5	-5.7	-5.5	-5.3	-5.4	-5.2	-5.8	-5.4	-5.5	-5.4	-5.5	-5.4	-5.5	-5.4	-5.8
Irritable Bowel Disease (IBD)	20.2	48.2	66.7	4.5	5.2	7.6	7.6	7.4	4.9	5.7	7.8	0.9	7.3	7.5	7.7	5.9	6.3	7.9	7.5	8.2	7.7	8.0	7.8	7.0	7.5	7.2
Exposure to tobacco smoke at home	19.7	22.2	28.1	-3.7	-3.0	-4.7	-4.7	-4.7	-5.2	-5.1	-4.5	-5.2	-4.7	-4.6	-4.8	-5.2	-4.6	-4.8	-4.8	-4.5	-4.8	-4.3	-4.7	-5.1	-4.7	-5.3
Miserableness	19.6	33.9	42.8	-5.2	-5.7	-5.7	-5.8	-5.9	-6.3	-6.4	-5.7	-5.7	-5.6	-5.9	-5.7	-5.8	-4.9	-6.3	-5.9	-5.6	-5.8	-5.4	-5.7	-6.2	-5.7	-6.5
Alcohol intake versus 10 years previously	18.4	27.6	34.9	-5.8	-5.7	-5.4	-5.6	-5.6	-3.1	-4.7	-5.7	-2.8	-5.6	-5.6	-5.4	-5.3	-5.6	-5.2	-5.3	-5.5	-5.4	-5.9	-5.4	-4.8	-5.4	-4.6
Leg pain on walking	18.3	22.9	27.8	-4.9	-5.2	-4.8	-4.7	-5.0	-3.8	-4.8	-4.7	-3.8	-5.3	-5.0	-4.8	-4.7	-4.8	-4.9	-4.9	-4.5	-4.8	-5.1	-4.8	-4.7	-4.9	-5.0
Arm fat percentage (left)	18.2	72.8	88.3	-9.3	-9.2	-8.8	-8.8	-9.2	-5.7	-6.6	-8.8	-6.1	-9.4	-9.2	-8.8	-8.6	-8.5	-8.8	-8.7	-8.9	-8.8	-9.2	-8.8	-8.2	-8.8	-7.7
Trunk fat mass	18.0	77.2	96.4	-9.8	-9.4	-9.1	-9.1	-9.5	-5.8	-6.8	-9.1	-6.2	-9.6	-9.5	-9.1	-8.9	-8.8	-9.0	-9.0	-9.0	-9.0	-9.5	-9.1	-8.4	-9.1	-7.9
Waist circumference	18.0	65.9	92.3	-9.6	-8.7	-8.2	-8.2	-8.7	-5.6	-6.6	-8.2	-6.9	-8.9	-8.7	-8.3	-8.4	-8.3	-8.0	-8.1	-7.8	-8.2	-8.7	-8.2	-7.7	-8.2	-7.4
Arm fat percentage (right)	17.8	70.3	83.7	-9.1	-8.9	-8.7	-8.6	-9.1	-5.8	-6.5	-8.6	-6.0	-9.1	-9.0	-8.6	-8.5	-8.4	-8.7	-8.6	-8.7	-8.6	-9.1	-8.6	-8.1	-8.6	-7.7
Body fat percentage	17.6	69.5	84.6	-9.2	-9.0	-8.7	-8.7	-9.0	-5.2	-6.2	-8.8	-5.3	-9.0	-9.0	-8.7	-8.5	-8.4	-8.5	-8.5	-8.7	-8.7	-9.2	-8.7	-7.9	-8.6	-7.3
Impedance of arm (right)	16.7	77.6	136.9	8.8	8.7	8.3	8.2	9.1	9.6	9.2	7.5	11.7	9.8	9.0	8.2	8.9	7.9	9.0	8.5	7.4	8.2	8.1	8.0	9.3	8.3	9.8
Ulcerative Colitis (UC)	16.5	30.9	43.8	3.6	4.4	5.8	5.9	5.8	5.1	5.3	5.9	2.4	5.7	5.9	5.9	4.8	4.7	6.6	5.8	6.4	5.9	6.0	6.0	5.9	5.8	6.4
Impedance of arm (left)	16.5	76.3	132.2	8.5	8.4	8.2	8.2	9.0	9.7	9.2	7.4	11.5	9.6	8.9	8.1	8.8	7.8	9.0	8.5	7.4	8.1	8.0	7.9	9.3	8.3	9.8
Crohns Disease (2012)	16.4	26.4	37.6	4.5	4.6	5.7	5.5	5.5	2.8	3.3	5.7	0.7	5.5	5.6	5.7	4.6	5.2	5.5	5.6	5.9	5.6	6.1	5.7	5.1	5.7	4.7
Mood swings	16.3	29.4	35.5	-5.0	-5.5	-5.4	-5.6	-5.6	-5.1	-6.0	-5.4	-5.1	-5.4	-5.6	-5.4	-5.7	-5.0	-5.5	-5.6	-5.2	-5.5	-5.1	-5.4	-5.5	-5.5	-5.4
Crohns Disease (2017)	15.9	34.8	50.1	4.0	4.0	6.7	6.6	6.4	3.1	4.3	6.9	-0.4	6.2	6.5	6.7	5.1	5.9	6.3	6.5	7.0	6.6	7.1	6.8	5.8	6.6	5.4
Arm fat-free mass (left)	15.4	77.9	93.7	-9.5	-9.0	-8.7	-8.7	-9.3	-8.1	-8.6	-8.2	-9.4	-9.7	-9.3	-8.6	-8.8	-8.1	-9.1	-8.8	-8.1	-8.6	-8.7	-8.5	-9.0	-8.7	-9.1
Arm predicted mass (left)	15.4	78.4	95.3	-9.6	-9.2	-8.7	-8.7	-9.4	-8.1	-8.5	-8.3	-9.4	-9.8	-9.3	-8.6	-8.8	-8.1	-9.1	-8.8	-8.1	-8.6	-8.8	-8.5	-9.0	-8.8	-9.1
Medication: Co-codamol	15.3	17.7	20.8	-3.7	-3.6	-4.3	-4.3	-4.4	-4.2	-4.0	-4.1	-3.5	-4.4	-4.4	-4.2	-4.2	-3.9	-4.6	-4.3	-4.2	-4.3	-4.3	-4.2	-4.5	-4.3	-4.6
Fed-up feelings	15.2	27.6	33.7	-4.0	-4.7	-5.4	-5.6	-5.6	-5.0	-5.5	-5.6	-3.4	-5.3	-5.5	-5.4	-5.0	-4.4	-5.8	-5.5	-5.5	-5.5	-5.2	-5.4	-5.5	-5.5	-5.7
Ulcerative Colitis	15.1	21.9	29.4	3.1	3.9	5.0	5.1	4.9	3.7	4.2	5.2	1.2	4.8	5.0	5.0	4.1	4.2	5.4	4.9	5.4	5.1	5.2	5.2	4.8	4.9	5.1
Arm predicted mass (right)	14.5	74.1	90.6	-9.3	-8.9	-8.5	-8.4	-9.1	-7.9	-8.4	-8.0	-9.3	-9.5	-9.1	-8.3	-8.5	-7.8	-8.9	-8.6	-7.9	-8.4	-8.4	-8.3	-8.8	-8.5	-8.9
Arm fat-free mass (right)	13.9	71.4	89.3	-9.2	-8.8	-8.3	-8.2	-8.9	-7.8	-8.2	-7.8	-9.3	-9.4	-8.9	-8.2	-8.3	-7.6	-8.6	-8.4	-7.7	-8.2	-8.2	-8.1	-8.6	-8.4	-8.7
Ever had bowel cancer screening	13.9	16.2	20.6	4.3	3.7	4.2	4.4	4.2	2.4	3.5	4.5	2.0	4.1	4.2	4.3	4.4	4.5	3.9	4.1	4.3	4.3	4.5	4.4	3.8	4.2	3.4
Trunk fat percentage	13.7	54.8	69.2	-8.3	-8.1	-7.8	-7.8	-8.1	-4.1	-5.1	-8.0	-4.1	-8.0	-8.1	-7.8	-7.5	-7.6	-7.5	-7.6	-7.9	-7.7	-8.3	-7.9	-6.9	-7.7	-6.2
Financial situation satisfaction	13.7	17.0	22.1	-3.4	-3.6	-4.3	-4.1	-4.3	-4.0	-4.7	-4.1	-4.0	-4.2	-4.3	-4.2	-4.2	-3.8	-4.1	-4.3	-3.9	-4.2	-3.8	-4.2	-4.4	-4.3	-4.1
Medication: Seretide 50 evohaler	13.6	15.7	18.7	-3.4	-3.0	-4.2	-4.0	-4.2	-3.4	-3.4	-4.3	-2.8	-4.0	-4.3	-4.1	-4.1	-3.9	-4.1	-4.3	-4.1	-4.2	-4.0	-4.2	-4.2	-4.3	-4.0
Depressed Affect (Nagel 2018)	13.3	28.1	34.9	-4.3	-4.9	-5.3	-5.4	-5.5	-5.7	-5.8	-5.4	-4.6	-5.3	-5.4	-5.3	-5.2	-4.4	-5.7	-5.4	-5.2	-5.4	-5.0	-5.4	-5.6	-5.3	-5.9
Ever highly irritable/argumentative for 2 days	13.2	15.9	27.8	-4.6	-5.3	-3.7	-3.7	-4.1	-4.2	-4.0	-3.8	-4.3	-4.0	-4.1	-3.7	-3.6	-2.9	-4.3	-3.8	-3.5	-3.7	-3.7	-3.7	-4.1	-3.7	-4.5
Basal metabolic rate	13.1	72.5	89.7	-9.3	-8.8	-8.4	-8.4	-9.0	-7.5	-8.1	-8.1	-8.8	-9.5	-9.0	-8.3	-8.4	-7.8	-8.8	-8.5	-8.0	-8.3	-8.5	-8.3	-8.6	-8.5	-8.7
Diabetes (self-reported)	12.9	19.8	30.5	-5.3	-3.9	-4.6	-4.5	-4.8	-2.6	-3.3	-4.7	-4.0	-4.6	-4.8	-4.6	-5.4	-5.5	-3.8	-4.5	-4.0	-4.6	-4.9	-4.6	-4.2	-4.6	-3.6
Impedance of whole body	12.8	65.4	132.2	7.9	8.1	7.4	7.3	8.2	9.3	8.8	6.5	11.5	9.2	8.2	7.3	7.9	6.8	8.4	7.7	6.8	7.3	7.1	7.1	8.6	7.5	9.2
Chronic bronchitis/emphysema (mother)	12.6	14.7	17.1	-4.1	-3.8	-3.8	-3.7	-4.0	-3.6	-3.6	-3.7	-3.6	-4.1	-4.0	-3.7	-3.9	-3.8	-3.9	-3.9	-3.5	-3.8	-3.8	-3.8	-3.9	-3.9	-4.0
Health satisfaction	12.5	16.2	20.2	-3.5	-3.5	-4.1	-4.1	-4.1	-4.0	-4.5	-4.1	-3.8	-3.8	-4.1	-4.1	-4.3	-3.7	-4.1	-4.2	-3.9	-4.1	-3.7	-4.1	-4.3	-4.1	-4.1
Qualifications: nursing, teaching	12.4	19.3	26.7	4.0	3.4	4.8	4.6	4.8	2.7	3.2	4.9	1.7	4.8	4.8	4.7	4.5	4.6	4.6	4.7	4.7	4.7	5.2	4.8	4.3	4.8	4.1
Pain experienced in last month	12.3	20.5	26.7	3.8	4.1	4.4	4.6	4.7	4.8	4.8	4.5	3.9	4.8	4.6	4.5	4.4	3.9	5.0	4.6	4.4	4.5	4.5	4.5	4.7	4.5	5.2
Qualifications: CSEs or equivalent	12.0	15.8	18.2	-3.9	-3.8	-4.1	-4.1	-4.1	-3.5	-3.7	-3.8	-3.2	-4.3	-4.1	-3.9	-4.1	-4.0	-4.1	-4.1	-3.9	-4.0	-4.1	-3.9	-4.3	-4.1	-4.1
Type 2 Diabetes (T2D) (2018)	11.7	22.0	35.2	-5.8	-4.5	-4.8	-4.7	-5.0	-2.4	-3.6	-4.9	-3.6	-5.0	-5.0	-4.8	-5.6	-5.9	-4.1	-4.8	-4.2	-4.8	-5.3	-4.8	-4.3	-4.8	-3.7
Diastolic blood pressure, automated reading	11.6	35.9	47.2	-5.8	-4.9	-6.5	-6.6	-6.4	-3.3	-4.7	-6.7	-2.8	-6.4	-6.4	-6.5	-6.5	-6.8	-5.7	-6.3	-6.2	-6.5	-6.9	-6.6	-5.6	-6.4	-5.0
Exposure to tobacco smoke outside home	11.5	15.3	18.7	-3.6	-3.6	-3.8	-3.9	-4.0	-3.8	-4.2	-3.8	-3.9	-4.1	-3.9	-3.9	-4.1	-3.8	-4.1	-3.8	-3.8	-3.9	-3.8	-3.9	-4.0	-3.8	-4.3
Leg fat-free mass (left)	11.4	60.3	77.6	-8.6	-8.3	-7.7	-7.6	-8.3	-6.6	-7.2	-7.4	-7.9	-8.8	-8.3	-7.6	-7.5	-7.0	-8.1	-7.8	-7.4	-7.6	-7.8	-7.5	-7.8	-7.8	-7.8
Leg predicted mass (left)	11.2	59.6	76.6	-8.5	-8.2	-7.7	-7.6	-8.2	-6.6	-7.2	-7.3	-7.9	-8.8	-8.2	-7.5	-7.5	-7.0	-8.0	-7.7	-7.4	-7.5	-7.7	-7.5	-7.7	-7.7	-7.8
Medication: Ventolin 100micrograms inhaler	10.9	14.0	18.5	-4.3	-3.8	-4.0	-3.6	-4.0	-2.3	-3.0	-4.1	-2.5	-4.1	-4.1	-3.8	-3.8	-3.8	-3.7	-4.0	-3.6	-3.8	-4.1	-3.9	-3.6	-4.0	-3.5
Prostate Cancer	10.7	15.0	19.7	-2.2	-1.9	-4.1	-4.1	-4.0	-4.3	-4.2	-4.1	-2.9	-3.5	-4.0	-4.1	-3.9	-3.6	-4.1	-4.1	-4.0	-4.1	-3.6	-4.1	-4.4	-4.1	-4.4
Hip circumference	10.6	45.8	58.8	-7.1	-7.2	-6.7	-6.7	-7.3	-6.0	-6.0	-6.5	-6.7	-7.7	-7.2	-6.7	-6.6	-6.1	-7.2	-6.8	-6.5	-6.7	-6.9	-6.7	-6.8	-6.7	-6.9
Age started oral contraceptive pill	10.6	13.3	15.9	3.7	3.9	3.8	3.7	3.9	2.9	3.1	3.6	3.2	4.0	3.8	3.8	4.0	3.7	3.5	3.7	3.5	3.7	3.6	3.7	3.7	3.7	3.3
Father’s age at death	10.4	14.0	18.4	2.6	3.2	3.9	4.0	3.9	3.5	4.3	3.7	2.5	3.7	3.9	4.0	3.8	3.4	3.9	4.0	4.0	3.9	3.6	3.8	4.0	3.9	3.7
Mouth/teeth dental problems: Dentures	10.3	17.4	21.0	-4.2	-4.5	-4.1	-4.0	-4.4	-4.2	-4.0	-3.9	-4.2	-4.5	-4.4	-4.0	-4.0	-3.5	-4.6	-4.2	-4.0	-4.0	-4.1	-3.9	-4.4	-4.1	-4.5
Whole body water mass	10.3	59.0	73.8	-8.4	-8.0	-7.5	-7.4	-8.1	-7.2	-7.6	-7.1	-8.6	-8.6	-8.1	-7.4	-7.5	-6.8	-7.9	-7.6	-7.0	-7.4	-7.5	-7.3	-7.9	-7.6	-8.0
Frequency of tenseness / restlessness in last 2 weeks	10.1	15.7	26.4	-3.4	-3.9	-3.7	-4.0	-3.8	-4.7	-5.1	-3.9	-4.3	-3.7	-3.8	-3.8	-3.7	-3.0	-4.2	-3.9	-3.8	-3.8	-3.4	-3.7	-4.3	-3.7	-4.6
Alcohol intake frequency.	10.1	23.6	36.5	-6.0	-5.7	-5.0	-5.1	-5.3	-2.3	-3.9	-5.3	-2.7	-5.3	-5.4	-5.0	-4.8	-5.1	-4.6	-4.8	-4.7	-5.0	-5.7	-5.0	-4.3	-4.9	-4.0
Whole body fat-free mass	10.0	57.2	72.1	-8.2	-7.8	-7.4	-7.3	-8.0	-7.1	-7.5	-7.0	-8.5	-8.5	-8.0	-7.3	-7.4	-6.7	-7.8	-7.5	-6.9	-7.3	-7.3	-7.2	-7.8	-7.5	-7.9
Diabetes diagnosed by doctor	10.0	16.4	27.4	-5.2	-3.9	-4.1	-4.0	-4.3	-2.1	-2.9	-4.2	-3.8	-4.3	-4.4	-4.1	-5.0	-5.2	-3.4	-4.0	-3.5	-4.1	-4.5	-4.1	-3.7	-4.1	-3.0
Pain all over the body in last month	9.9	10.6	16.4	-2.6	-3.1	-3.1	-3.4	-3.2	-4.1	-3.9	-3.1	-3.4	-3.1	-3.2	-3.2	-2.7	-2.2	-3.7	-3.2	-3.3	-3.2	-2.9	-3.1	-3.6	-3.1	-3.9
Maternal smoking around birth	9.6	13.9	18.0	-3.9	-3.9	-3.6	-3.7	-3.8	-3.5	-3.9	-3.2	-4.1	-4.2	-3.7	-3.6	-4.2	-3.9	-3.6	-3.7	-3.4	-3.6	-3.6	-3.5	-3.7	-3.7	-3.6
Ever unenthusiastic/disinterested for a whole week	9.5	11.6	22.0	-3.1	-3.7	-3.1	-3.0	-3.2	-4.7	-4.3	-3.1	-4.4	-3.0	-3.3	-3.1	-3.2	-2.4	-3.7	-3.3	-2.8	-3.0	-2.7	-3.0	-3.7	-3.2	-4.4
Frequency of unenthusiasm / disinterest in last 2 weeks	9.4	12.5	15.8	-3.3	-3.6	-3.6	-3.9	-3.6	-2.9	-3.6	-4.0	-2.1	-3.3	-3.6	-3.7	-3.8	-3.5	-3.5	-3.7	-3.7	-3.7	-3.6	-3.7	-3.5	-3.6	-3.4
Leg fat-free mass (right)	9.4	50.2	65.3	-7.9	-7.6	-7.0	-6.9	-7.5	-6.1	-6.7	-6.6	-7.5	-8.1	-7.5	-6.9	-6.9	-6.4	-7.3	-7.1	-6.7	-6.9	-7.0	-6.8	-7.1	-7.0	-7.1
Medication for cholesterol, blood pressure or diabetes	9.2	15.3	19.0	4.2	3.6	4.1	4.1	4.2	2.6	2.8	4.1	3.1	4.3	4.1	4.2	4.3	4.4	3.7	4.0	3.9	4.1	4.2	4.1	3.9	4.0	3.4
Leg predicted mass (right)	9.2	49.3	64.4	-7.9	-7.5	-6.9	-6.9	-7.5	-6.0	-6.6	-6.5	-7.4	-8.0	-7.5	-6.8	-6.8	-6.4	-7.3	-7.0	-6.6	-6.8	-7.0	-6.7	-7.0	-7.0	-7.0
Guilty feelings	8.8	13.3	17.4	-2.4	-2.3	-3.8	-3.9	-3.7	-4.1	-4.0	-3.7	-3.0	-3.5	-3.7	-3.8	-3.6	-3.1	-4.0	-3.9	-3.8	-3.8	-3.4	-3.8	-4.1	-3.8	-4.2
Blood White Count	8.7	64.7	74.6	-8.4	-7.1	-8.3	-8.2	-8.6	-6.2	-7.9	-8.0	-7.1	-8.4	-8.6	-8.2	-8.3	-7.9	-8.3	-8.3	-8.1	-8.2	-8.3	-8.1	-8.1	-8.3	-7.7
Qualifications: NVQ or HND or HNC or equivalent	8.7	10.5	22.2	-4.6	-4.7	-3.3	-3.2	-3.6	-1.3	-2.0	-3.2	-2.0	-3.7	-3.6	-3.1	-3.1	-3.3	-3.1	-3.2	-3.2	-3.1	-3.7	-3.1	-2.8	-3.3	-2.4
Qualifications: O levels/GCSEs or equivalent	8.5	13.5	16.9	2.9	2.8	3.7	3.7	3.8	3.8	3.7	3.5	3.7	3.8	3.7	3.8	3.8	3.5	4.1	3.6	3.8	3.7	3.6	3.7	3.9	3.6	4.1
Coronary Artery Disease (CAD)	8.3	9.9	11.6	-3.4	-3.0	-3.2	-3.2	-3.4	-2.5	-2.9	-2.9	-2.9	-3.2	-3.4	-3.1	-3.1	-3.1	-3.3	-3.2	-3.3	-3.2	-3.3	-3.1	-3.2	-3.2	-3.0
Neuroticism score	8.1	16.9	19.6	-3.9	-3.8	-4.1	-4.3	-4.2	-4.0	-4.4	-4.3	-3.6	-3.7	-4.3	-4.1	-4.4	-3.8	-4.2	-4.2	-3.9	-4.2	-4.0	-4.1	-4.2	-4.2	-4.3
Trunk fat-free mass	8.1	46.4	65.7	-7.2	-6.8	-6.6	-6.5	-7.1	-6.9	-7.1	-6.1	-8.1	-7.6	-7.1	-6.5	-6.6	-5.8	-7.0	-6.8	-6.0	-6.5	-6.4	-6.4	-7.1	-6.7	-7.4
Trunk predicted mass	7.9	44.9	64.2	-7.1	-6.6	-6.5	-6.4	-7.0	-6.7	-6.9	-6.0	-8.0	-7.4	-7.0	-6.4	-6.5	-5.8	-6.9	-6.6	-5.9	-6.4	-6.3	-6.3	-7.0	-6.6	-7.2
Pulse rate, automated reading	7.9	25.6	45.2	-6.5	-4.9	-5.6	-5.6	-5.4	1.7	-1.3	-6.3	1.4	-5.0	-5.6	-5.6	-5.3	-6.6	-3.8	-5.2	-5.5	-5.6	-6.7	-5.7	-3.2	-5.6	-1.5
Loneliness, isolation	7.9	10.9	13.5	-2.6	-2.9	-3.4	-3.4	-3.5	-3.4	-3.4	-3.3	-2.6	-3.4	-3.5	-3.3	-3.3	-2.9	-3.6	-3.5	-3.2	-3.4	-3.3	-3.3	-3.7	-3.5	-3.7
Major Depression (MDD)	7.6	9.2	15.2	-2.4	-2.8	-2.9	-3.0	-3.0	-3.9	-3.8	-2.6	-3.7	-3.0	-2.9	-2.8	-2.9	-2.3	-3.2	-2.9	-2.7	-2.9	-2.5	-2.7	-3.6	-2.8	-3.5
Bilateral oophorectomy (both ovaries removed)	7.6	8.8	13.1	-3.4	-3.6	-2.9	-3.0	-3.0	-2.7	-2.7	-2.9	-2.9	-3.1	-2.9	-2.9	-3.0	-2.9	-3.0	-2.8	-2.9	-2.9	-3.0	-2.9	-3.1	-2.7	-3.0
Shortness of breath walking on level ground	7.4	8.8	13.5	-3.3	-3.7	-2.9	-2.8	-3.1	-2.7	-3.1	-2.8	-2.8	-3.2	-3.1	-2.9	-2.6	-2.3	-3.1	-3.0	-2.8	-2.9	-2.9	-2.9	-3.0	-3.0	-3.2
Heel bone mineral density (BMD) T-score, automated (left)	7.2	16.3	27.1	-5.1	-4.0	-4.4	-4.4	-4.6	-0.1	-1.8	-4.6	-0.8	-4.4	-4.6	-4.3	-4.3	-5.2	-3.3	-4.2	-4.2	-4.4	-5.1	-4.4	-3.0	-4.4	-2.1
Medication: Omeprazole	7.2	8.6	10.6	-3.1	-3.3	-2.9	-3.0	-3.0	-2.4	-2.7	-3.1	-2.2	-3.0	-3.1	-2.9	-3.1	-3.1	-3.0	-2.9	-2.8	-2.9	-3.1	-2.9	-2.8	-2.9	-3.1
Osteoarthritis (self-reported)	7.2	9.4	12.2	-3.2	-3.5	-3.1	-3.0	-3.3	-2.5	-2.9	-3.1	-2.1	-3.2	-3.4	-3.0	-2.8	-2.8	-3.2	-3.1	-2.9	-3.1	-3.3	-3.2	-3.1	-3.1	-3.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	7.2	15.2	25.8	2.5	2.3	3.9	4.0	3.8	5.1	4.6	3.7	3.7	3.5	3.8	4.0	4.0	3.3	4.3	4.0	3.9	4.0	3.4	4.0	4.6	3.9	4.7
Neuroticism	7.0	16.9	19.5	-3.8	-3.9	-4.1	-4.3	-4.2	-4.3	-4.3	-4.3	-3.7	-3.8	-4.2	-4.1	-4.3	-3.7	-4.2	-4.2	-3.9	-4.2	-3.9	-4.2	-4.3	-4.1	-4.4
Impedance of leg (left)	7.0	34.2	77.6	5.9	6.2	5.3	5.1	5.9	6.7	6.2	4.5	8.8	7.0	5.8	5.2	5.5	4.7	6.2	5.5	5.0	5.2	5.0	5.0	6.2	5.4	6.7
Basal cell carcinoma (self-reported)	6.9	8.2	10.0	2.7	2.6	3.1	2.9	3.0	2.1	2.8	3.1	1.5	2.9	3.1	3.1	2.9	2.8	2.9	3.1	2.9	3.1	3.1	3.2	2.8	3.1	2.7
Prospective memory result	6.8	8.4	13.8	-3.6	-3.7	-2.9	-2.8	-3.2	-1.9	-2.3	-2.9	-2.4	-3.1	-3.2	-2.9	-2.7	-2.6	-3.1	-2.9	-3.1	-2.8	-2.9	-2.8	-2.7	-3.0	-2.6
Respiratory disease	6.7	14.9	23.4	-4.7	-4.6	-3.6	-3.5	-3.8	-4.0	-3.9	-3.6	-4.8	-3.9	-3.9	-3.6	-3.7	-3.2	-4.0	-3.6	-3.3	-3.5	-3.4	-3.6	-4.1	-3.6	-4.3
Number of operations (self-reported)	6.7	9.9	18.3	-2.9	-3.8	-2.8	-2.7	-3.1	-4.3	-4.0	-2.6	-3.8	-3.3	-3.1	-2.7	-2.5	-1.9	-3.5	-3.0	-2.6	-2.7	-2.5	-2.7	-3.5	-2.9	-4.1
Forced expiratory volume in 1-second (FEV1), Best measure	6.5	20.6	31.8	2.8	3.0	4.6	4.6	4.5	5.6	5.2	4.2	4.3	4.3	4.5	4.7	4.5	3.8	5.1	4.7	4.7	4.7	4.0	4.6	5.2	4.6	5.3
Knee pain experienced in last month	6.5	10.1	18.1	-3.5	-4.2	-3.0	-2.9	-3.4	-3.2	-3.1	-2.9	-3.1	-3.7	-3.4	-2.9	-2.7	-2.4	-3.4	-3.1	-2.7	-2.9	-3.2	-3.0	-3.3	-3.1	-3.6
Medication: Paracetamol	6.4	9.9	22.2	-1.3	-2.2	-3.0	-3.0	-3.0	-4.7	-4.3	-3.0	-3.0	-3.0	-3.0	-2.9	-2.8	-1.9	-3.7	-3.2	-3.0	-3.0	-2.5	-3.0	-3.8	-3.0	-4.3
Medication: Blood pressure	6.3	11.1	13.8	-3.4	-3.0	-3.5	-3.4	-3.5	-2.6	-2.7	-3.4	-2.9	-3.6	-3.5	-3.5	-3.7	-3.7	-3.2	-3.4	-3.2	-3.4	-3.5	-3.4	-3.4	-3.4	-3.1
Number of self-reported non-cancer illnesses	6.3	11.0	14.9	-3.6	-3.5	-3.2	-3.1	-3.3	-3.5	-3.3	-3.3	-3.4	-3.1	-3.4	-3.2	-3.3	-2.9	-3.5	-3.3	-2.9	-3.2	-3.2	-3.2	-3.6	-3.2	-3.9
Impedance of leg (right)	6.2	30.1	71.6	5.6	5.7	4.9	4.8	5.6	6.3	5.8	4.1	8.5	6.6	5.5	4.8	5.2	4.5	5.8	5.1	4.6	4.8	4.7	4.6	5.7	5.0	6.2
Age when periods started (menarche)	6.2	14.8	34.2	-2.4	-3.6	-3.4	-3.7	-3.6	-5.8	-5.3	-3.5	-3.9	-3.7	-3.5	-3.4	-3.0	-2.2	-4.7	-3.6	-3.6	-3.5	-3.2	-3.5	-4.4	-3.4	-5.5
Forced expiratory volume in 1-second (FEV1)	6.1	20.7	35.0	2.3	2.6	4.6	4.6	4.5	5.9	5.5	4.2	4.6	4.3	4.4	4.7	4.6	3.6	5.1	4.7	4.8	4.7	3.8	4.6	5.4	4.5	5.2
Mother’s age at death	6.1	7.7	13.4	2.3	2.3	2.6	2.7	2.7	3.6	3.5	2.3	3.7	2.8	2.6	2.6	2.9	2.4	2.8	2.6	2.5	2.6	2.2	2.4	3.1	2.5	3.2
Medication: Metformin	6.0	8.5	13.7	-3.5	-2.8	-3.0	-2.9	-3.1	-1.5	-2.2	-3.0	-2.9	-3.2	-3.1	-3.0	-3.5	-3.7	-2.4	-2.9	-2.5	-3.0	-3.1	-3.0	-2.7	-3.0	-2.1
Number of live births	6.0	8.5	13.2	-3.6	-3.6	-2.8	-2.8	-3.1	-1.9	-2.1	-2.8	-2.6	-3.5	-3.1	-2.8	-3.0	-3.0	-3.0	-2.8	-2.7	-2.8	-3.2	-2.9	-2.7	-2.8	-2.7
Mean time to correctly identify matches	6.0	11.5	15.8	3.8	3.4	3.8	3.8	3.8	1.2	2.2	3.8	0.9	3.7	3.8	3.7	3.3	3.5	3.2	3.6	3.7	3.7	4.0	3.7	3.0	3.8	2.4
Neck or shoulder pain in last month	5.9	8.4	13.2	-2.3	-2.8	-2.7	-2.7	-2.9	-3.5	-3.6	-2.8	-3.1	-3.0	-2.9	-2.8	-2.8	-2.3	-3.1	-2.8	-2.5	-2.7	-2.7	-2.8	-3.2	-2.7	-3.5
Breast Cancer	5.8	14.1	17.5	2.6	2.5	4.1	4.0	3.9	3.3	4.0	3.9	2.0	3.7	3.9	4.0	3.6	3.3	4.0	4.2	4.0	4.1	3.8	4.1	4.0	4.2	4.0
Long-standing illness, disability or infirmity	5.6	8.6	16.4	-3.6	-3.2	-2.7	-2.6	-2.9	-2.8	-3.0	-2.7	-4.0	-3.0	-3.0	-2.7	-3.3	-3.0	-2.6	-2.8	-2.1	-2.7	-2.7	-2.7	-2.9	-2.7	-3.0
Asthma (self-reported)	5.6	11.2	18.4	-4.2	-4.3	-3.1	-3.1	-3.3	-3.2	-3.2	-3.2	-3.8	-3.5	-3.4	-3.1	-3.0	-2.7	-3.6	-3.1	-3.1	-3.1	-3.1	-3.2	-3.4	-3.1	-3.7
Lung FVC	5.5	28.0	37.8	3.4	2.9	5.5	5.5	5.3	6.1	6.0	5.4	4.0	4.6	5.3	5.6	5.4	4.6	5.9	5.6	5.6	5.5	4.9	5.5	6.1	5.5	6.0
Asthma	5.5	10.8	17.5	-4.2	-4.2	-3.1	-3.0	-3.3	-3.2	-3.2	-3.1	-3.8	-3.4	-3.3	-3.0	-3.0	-2.6	-3.5	-3.1	-3.0	-3.0	-3.0	-3.1	-3.4	-3.0	-3.6
Medication: Paracetamol	5.5	9.0	20.8	-1.2	-1.9	-2.8	-3.0	-2.8	-4.6	-4.0	-2.9	-2.8	-2.7	-2.8	-2.9	-2.8	-2.0	-3.5	-3.0	-2.8	-2.9	-2.4	-2.9	-3.7	-2.8	-4.1
Ever depressed for a whole week	5.4	6.7	18.6	-2.1	-2.4	-2.1	-2.1	-2.2	-4.3	-3.5	-2.1	-4.3	-2.0	-2.2	-2.1	-2.3	-1.5	-2.8	-2.2	-1.9	-2.1	-1.8	-2.1	-3.0	-2.1	-3.6
Schizophrenia vs Biploar Disorder	5.2	6.9	9.8	3.0	3.1	2.4	2.5	2.7	2.6	2.4	2.7	2.6	2.7	2.8	2.5	2.2	2.0	3.0	2.5	2.4	2.4	2.6	2.5	2.7	2.4	3.1
Heel bone mineral density (BMD) T-score, automated (right)	5.2	12.0	23.1	-4.8	-3.6	-3.7	-3.8	-3.9	0.7	-0.8	-4.0	0.1	-3.5	-3.9	-3.7	-3.7	-4.8	-2.7	-3.4	-3.6	-3.7	-4.6	-3.8	-2.2	-3.7	-1.4
Had major operations	5.2	6.1	13.2	-1.0	-0.9	-2.4	-2.4	-2.4	-3.6	-3.2	-2.4	-2.5	-2.1	-2.4	-2.5	-2.3	-1.8	-2.8	-2.5	-2.3	-2.4	-2.0	-2.4	-3.0	-2.4	-3.4
Average weekly champagne plus white wine intake	5.2	7.1	10.9	2.9	2.2	2.8	2.9	2.9	1.4	2.0	3.0	0.9	2.8	2.9	2.9	2.6	2.8	2.8	2.8	2.8	2.9	3.3	3.0	2.4	2.8	2.3
Systolic blood pressure, automated reading	5.1	14.8	21.5	-2.4	-1.7	-4.0	-4.1	-3.9	-3.7	-4.0	-3.8	-3.4	-3.9	-3.8	-4.2	-4.6	-4.6	-3.6	-4.1	-3.7	-4.1	-3.8	-4.1	-4.1	-4.0	-3.9
Tinnitus: Yes, but not now, but have in the past	5.0	5.4	7.3	-2.0	-2.6	-2.5	-2.5	-2.5	-1.7	-2.0	-2.5	-0.7	-2.3	-2.5	-2.5	-2.0	-2.0	-2.5	-2.5	-2.7	-2.5	-2.4	-2.4	-2.4	-2.5	-2.2
Alcohol usually taken with meals	5.0	8.0	9.4	2.8	2.7	2.8	2.9	2.9	2.6	3.0	2.6	2.9	2.9	2.8	2.9	3.1	2.8	2.9	2.7	2.8	2.8	2.7	2.8	2.9	2.7	3.0
Breastfed as a baby	5.0	6.2	9.1	3.0	2.6	2.5	2.6	2.6	1.9	1.9	2.6	2.3	2.2	2.6	2.4	3.0	3.0	2.3	2.5	2.2	2.5	2.6	2.4	2.5	2.5	2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	5.0	5.9	7.5	-2.3	-2.4	-2.5	-2.5	-2.5	-2.0	-2.2	-2.5	-1.6	-2.4	-2.5	-2.4	-2.7	-2.7	-2.4	-2.5	-2.4	-2.5	-2.5	-2.5	-2.4	-2.5	-2.5
Neuroticism (Nagel 2018)	4.9	11.5	14.5	-3.2	-3.3	-3.3	-3.6	-3.4	-3.8	-3.6	-3.7	-3.1	-2.8	-3.4	-3.4	-3.4	-2.9	-3.5	-3.4	-3.2	-3.4	-3.2	-3.4	-3.5	-3.4	-3.8
Heart attack	4.9	6.2	9.1	-2.4	-2.4	-2.6	-2.6	-2.6	-1.8	-2.3	-2.5	-1.8	-2.8	-2.6	-2.6	-3.0	-3.0	-2.3	-2.5	-2.3	-2.6	-2.7	-2.6	-2.5	-2.5	-2.2
Number of full brothers	4.9	6.2	12.2	-1.8	-2.3	-2.3	-2.2	-2.5	-3.5	-3.1	-2.1	-3.2	-2.4	-2.4	-2.3	-2.4	-1.6	-2.8	-2.4	-2.1	-2.2	-2.0	-2.3	-2.9	-2.3	-3.2
Diabetes (mother)	4.7	6.0	9.6	-2.6	-1.5	-2.7	-2.6	-2.6	-1.5	-1.7	-2.6	-1.9	-2.3	-2.7	-2.7	-2.9	-3.1	-2.2	-2.6	-2.5	-2.6	-2.7	-2.5	-2.4	-2.7	-1.9
Chest pain or discomfort	4.7	6.7	15.7	-2.3	-3.0	-2.2	-2.2	-2.5	-4.0	-2.8	-2.1	-3.7	-2.4	-2.5	-2.2	-2.0	-1.2	-3.2	-2.4	-2.2	-2.2	-1.9	-2.1	-3.0	-2.2	-3.6
Body Mass Index (BMI) (2010)	4.6	6.4	10.5	-3.2	-3.2	-2.4	-2.4	-2.7	-2.0	-2.2	-2.2	-2.8	-2.9	-2.7	-2.4	-2.5	-2.3	-2.5	-2.4	-2.3	-2.3	-2.6	-2.4	-2.4	-2.4	-2.4
Heel T-Score	4.6	36.9	85.9	-9.3	-8.5	-6.4	-6.3	-6.8	1.4	-1.7	-6.7	-1.3	-7.0	-6.9	-6.3	-5.7	-7.2	-4.7	-5.9	-6.4	-6.3	-7.4	-6.3	-3.9	-6.3	-2.0
Forced vital capacity (FVC), Best measure	4.6	16.8	22.0	3.0	3.1	4.1	4.1	4.1	4.7	4.4	3.9	3.8	3.8	4.1	4.2	4.3	3.8	4.5	4.2	4.2	4.2	3.8	4.2	4.5	4.1	4.7
Myopia	4.6	6.7	11.1	1.5	0.6	2.9	2.8	2.7	1.9	2.7	2.8	1.4	2.5	2.6	2.9	3.3	3.3	2.2	2.8	2.5	2.9	2.7	2.9	2.6	2.9	2.1
Reaction Time	4.5	8.5	12.5	3.1	2.5	3.3	3.2	3.2	0.9	1.6	3.3	0.5	3.3	3.2	3.3	2.9	3.3	2.7	3.1	3.2	3.3	3.5	3.3	2.6	3.2	2.1
Smoking Status	4.4	10.5	27.1	-1.9	-2.7	-2.8	-2.8	-2.9	-5.2	-4.2	-2.4	-4.5	-3.4	-2.8	-2.9	-2.9	-2.0	-3.8	-2.9	-2.8	-2.8	-2.4	-2.8	-3.8	-2.8	-4.5
Pain type(s) experienced in last month: Hip pain	4.4	5.6	7.6	-2.4	-2.5	-2.3	-2.2	-2.4	-2.2	-2.6	-2.2	-2.3	-2.8	-2.4	-2.2	-2.3	-2.2	-2.5	-2.3	-2.1	-2.2	-2.3	-2.3	-2.4	-2.3	-2.6
Lung cancer (father)	4.3	5.0	6.0	-2.0	-2.3	-2.4	-2.3	-2.4	-1.5	-2.2	-2.4	-1.2	-2.5	-2.4	-2.4	-2.2	-2.1	-2.3	-2.4	-2.3	-2.3	-2.4	-2.4	-2.1	-2.4	-2.0
Number of full sisters	4.3	5.2	9.5	-2.9	-2.8	-1.9	-2.2	-2.2	-2.4	-2.4	-2.0	-3.1	-2.2	-2.1	-2.0	-2.6	-2.3	-2.2	-2.0	-1.6	-2.0	-2.3	-2.0	-2.1	-2.0	-2.5
Commuting to job workplace: Public transport	4.3	5.1	7.1	2.1	2.4	2.2	2.2	2.2	2.3	2.3	2.2	2.2	2.3	2.2	2.2	2.7	2.4	2.2	2.2	1.9	2.2	2.1	2.2	2.5	2.2	2.4
Noisy workplace	4.2	5.2	8.8	-2.7	-3.0	-2.0	-2.2	-2.3	-2.1	-2.6	-2.3	-2.3	-2.3	-2.3	-2.1	-2.1	-1.9	-2.5	-2.1	-2.1	-2.1	-2.4	-2.1	-2.1	-2.0	-2.5
Medication: Cholesterol lowering	4.2	6.5	9.0	-2.7	-2.3	-2.8	-2.7	-2.8	-1.5	-1.5	-2.6	-1.8	-3.0	-2.7	-2.8	-2.9	-3.0	-2.3	-2.6	-2.5	-2.7	-2.9	-2.7	-2.5	-2.7	-2.1
Heart attack/myocardial infarction (self-reported)	4.2	5.4	7.9	-2.1	-2.2	-2.4	-2.4	-2.4	-1.7	-2.2	-2.3	-1.6	-2.6	-2.4	-2.5	-2.8	-2.8	-2.1	-2.3	-2.1	-2.4	-2.5	-2.4	-2.3	-2.3	-2.0
Average weekly spirits intake	4.1	5.1	8.7	-1.3	-1.8	-2.5	-2.4	-2.5	-1.9	-2.1	-2.5	-0.0	-2.1	-2.5	-2.5	-1.7	-1.6	-2.9	-2.5	-3.0	-2.5	-2.4	-2.6	-2.4	-2.5	-2.4
Medication: Ramipril	4.1	5.2	8.6	-2.1	-1.7	-2.2	-2.3	-2.2	-2.5	-2.3	-2.0	-2.9	-2.3	-2.2	-2.2	-2.9	-2.7	-2.0	-2.3	-1.9	-2.2	-2.0	-2.1	-2.4	-2.2	-2.4
Alcohol drinker status: Previous	4.1	4.7	8.6	-1.5	-1.8	-2.0	-2.2	-2.2	-2.8	-2.8	-1.8	-2.9	-2.5	-2.1	-2.1	-1.9	-1.6	-2.2	-2.2	-2.0	-2.1	-1.7	-2.0	-2.3	-2.1	-2.5
Neuroticism (2016)	4.0	5.8	7.7	-1.6	-2.0	-2.5	-2.5	-2.5	-2.6	-2.5	-2.6	-1.8	-2.1	-2.5	-2.5	-2.5	-2.2	-2.6	-2.6	-2.5	-2.5	-2.2	-2.5	-2.7	-2.5	-2.8
Forced vital capacity (FVC)	4.0	15.5	22.1	2.4	2.5	4.0	4.0	4.0	4.7	4.5	3.7	3.8	3.7	3.9	4.1	4.2	3.6	4.3	4.0	4.1	4.0	3.5	4.0	4.5	3.9	4.5
Peak expiratory flow (PEF)	4.0	9.2	12.4	1.9	1.6	3.2	3.2	3.1	3.4	3.3	3.0	2.2	2.6	3.1	3.2	2.9	2.4	3.5	3.3	3.5	3.2	2.8	3.2	3.5	3.2	3.4
Number of children fathered	3.9	4.4	6.5	-2.5	-2.5	-2.0	-2.0	-2.2	-1.6	-2.0	-2.1	-1.5	-2.4	-2.2	-2.0	-1.8	-1.7	-2.4	-2.0	-2.1	-2.0	-2.3	-2.1	-2.0	-2.0	-2.2
Average weekly red wine intake	3.9	5.8	10.7	3.2	3.2	2.1	2.2	2.5	2.6	2.5	2.0	3.3	2.3	2.5	2.0	2.3	1.9	2.6	2.2	2.0	2.1	2.2	1.9	2.4	2.1	2.8
Systolic Blood Pressure	3.8	19.2	33.6	-2.9	-1.6	-4.9	-5.0	-4.5	-2.8	-3.7	-5.0	-1.7	-4.3	-4.4	-5.0	-5.5	-5.8	-3.8	-4.8	-4.4	-5.0	-4.9	-4.9	-4.4	-4.8	-3.7
Seen doctor (GP) for nerves, anxiety, tension or depression	3.8	5.8	12.9	-2.5	-3.3	-2.0	-2.1	-2.2	-3.5	-3.1	-1.8	-3.6	-2.1	-2.2	-2.0	-2.1	-1.4	-2.7	-2.1	-2.0	-2.0	-1.7	-1.9	-2.6	-2.0	-3.1
Medication for pain relief, constipation, heartburn	3.8	6.5	12.9	1.5	1.7	2.4	2.5	2.4	3.6	3.0	2.4	3.1	2.4	2.4	2.4	2.9	2.2	2.7	2.5	2.1	2.4	2.1	2.4	3.1	2.3	3.2
Supplements: Calcium	3.8	4.2	7.7	2.1	1.4	2.3	2.2	2.2	0.1	1.0	2.5	-0.1	2.2	2.3	2.3	2.5	2.8	1.6	2.2	2.2	2.3	2.6	2.3	1.6	2.4	1.1
Hand grip strength (right)	3.7	10.1	13.8	-2.6	-2.3	-3.4	-3.5	-3.5	-2.2	-3.0	-3.6	-1.3	-3.6	-3.5	-3.4	-2.6	-2.6	-3.5	-3.4	-3.7	-3.5	-3.5	-3.4	-3.1	-3.5	-3.0
Current tobacco smoking	3.7	6.0	9.5	-2.1	-2.3	-2.2	-2.4	-2.4	-3.1	-3.0	-2.1	-2.5	-2.5	-2.4	-2.3	-2.3	-1.8	-3.0	-2.3	-2.4	-2.3	-2.3	-2.3	-2.6	-2.2	-3.1
Commuting to job workplace: Walk	3.7	4.0	5.9	2.3	2.4	1.8	1.9	1.9	2.0	1.7	1.9	1.9	2.0	1.9	1.9	2.0	2.1	2.2	1.8	2.0	1.9	2.0	2.0	1.9	1.8	2.4
Back pain experienced in last month	3.7	5.4	6.5	-1.9	-2.3	-2.4	-2.5	-2.5	-2.3	-2.5	-2.3	-1.5	-2.5	-2.4	-2.2	-2.2	-1.9	-2.5	-2.5	-2.3	-2.4	-2.2	-2.4	-2.4	-2.5	-2.5
HDL Cholesterol	3.6	5.9	17.7	4.2	3.8	2.3	2.3	2.6	0.2	1.2	2.6	1.5	2.6	2.7	2.2	2.4	3.0	2.0	2.2	2.1	2.3	3.0	2.4	1.7	2.3	1.5
Chronotype (morning person)	3.6	8.4	18.4	2.6	3.0	2.7	2.7	2.7	3.8	3.2	3.0	1.4	2.2	2.8	2.7	2.6	2.1	3.6	2.8	2.7	2.7	3.0	2.9	3.2	2.7	4.3
Pack years adult smoking proportion	3.6	5.5	11.0	-1.1	-1.5	-2.2	-2.3	-2.3	-3.3	-3.0	-2.0	-3.2	-2.5	-2.2	-2.2	-2.3	-1.6	-2.5	-2.4	-2.1	-2.3	-1.7	-2.1	-2.7	-2.3	-2.7
Financial difficulties in last 2 years	3.6	4.8	5.8	-1.9	-2.0	-2.2	-2.3	-2.4	-2.1	-2.0	-2.3	-1.8	-2.2	-2.4	-2.2	-2.2	-2.0	-2.3	-2.3	-2.1	-2.3	-2.2	-2.2	-2.2	-2.3	-2.2
Illnesses of siblings: Diabetes	3.6	4.5	13.0	-3.3	-3.6	-1.8	-1.8	-2.1	-1.7	-1.8	-1.9	-2.4	-2.0	-2.2	-1.7	-2.1	-2.0	-2.0	-1.8	-1.5	-1.8	-2.1	-1.8	-2.0	-1.8	-2.1
Smoking status: Current	3.6	5.7	8.2	-2.2	-2.3	-2.3	-2.4	-2.4	-2.7	-2.9	-2.2	-2.1	-2.4	-2.4	-2.3	-2.3	-1.9	-2.8	-2.3	-2.5	-2.3	-2.4	-2.3	-2.5	-2.3	-2.8
Medication: Gliclazide	3.5	4.0	6.7	-2.6	-2.0	-2.1	-2.0	-2.1	-1.1	-1.7	-2.1	-1.9	-1.9	-2.1	-2.1	-2.3	-2.3	-1.7	-2.0	-1.8	-2.0	-2.1	-2.1	-1.9	-2.0	-1.5
Medication: Lansoprazole	3.4	3.8	9.0	-2.4	-3.0	-1.9	-1.9	-2.0	-1.0	-1.7	-2.0	-1.2	-2.2	-2.1	-1.9	-1.8	-2.0	-1.8	-1.9	-1.7	-1.9	-2.1	-2.0	-1.7	-1.9	-1.7
Blood Eosinophil Count	3.2	24.6	61.3	-7.8	-5.6	-4.9	-5.1	-5.2	-1.6	-3.5	-5.3	-3.1	-5.1	-5.3	-4.8	-5.1	-5.8	-4.7	-4.6	-5.1	-4.9	-5.9	-5.0	-4.0	-4.8	-3.8
Medication: Omeprazole (e.g. Zanprol)	3.2	3.9	8.4	-2.4	-2.9	-1.8	-1.9	-1.9	-1.8	-1.8	-2.0	-1.9	-1.9	-2.0	-1.8	-1.9	-1.8	-2.0	-1.8	-1.7	-1.8	-2.0	-1.8	-1.9	-1.8	-2.2
Reason for reducing amount of alcohol drunk: Health precaution	3.1	3.6	5.6	1.3	0.8	2.0	1.9	2.0	2.2	1.9	1.8	1.7	1.9	2.0	2.0	1.9	1.8	2.2	2.0	1.8	1.9	2.0	2.0	2.2	1.9	2.4
Hair/balding pattern: Pattern 2	3.0	3.8	8.3	-2.9	-2.7	-1.8	-1.7	-1.9	-1.7	-2.3	-1.9	-2.5	-1.9	-1.9	-1.7	-2.0	-1.7	-1.8	-1.8	-1.5	-1.7	-1.8	-1.7	-1.9	-1.7	-1.9
Illnesses of siblings	3.0	4.2	6.1	2.3	2.5	2.0	1.9	2.1	2.1	1.8	2.0	2.5	1.9	2.1	1.9	2.2	1.8	1.9	2.1	1.5	2.0	1.8	2.0	2.2	2.0	2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.0	3.5	5.5	-1.2	-0.9	-1.9	-1.9	-1.9	-2.4	-2.3	-1.8	-2.0	-1.5	-1.9	-1.9	-2.1	-1.8	-1.9	-1.9	-1.7	-1.9	-1.7	-1.8	-2.1	-1.9	-2.2
Lung FEV1/FVC ratio	2.9	14.5	37.5	1.2	1.6	3.8	4.0	3.6	6.1	4.8	3.1	4.9	3.6	3.4	3.9	3.2	2.0	4.0	4.0	3.9	3.9	2.2	3.5	4.8	3.8	4.5
Illnesses of mother	2.9	3.6	6.4	2.1	1.2	2.0	2.0	2.0	1.0	1.1	2.1	1.5	2.0	2.0	2.0	2.4	2.5	1.5	2.0	1.6	2.0	2.1	2.0	1.8	2.0	1.4
Ever had stillbirth, spontaneous miscarriage or termination	2.9	3.1	5.6	-1.5	-1.6	-1.8	-1.8	-1.8	-1.7	-1.9	-1.6	-2.4	-2.0	-1.8	-1.8	-2.0	-1.8	-1.5	-1.9	-1.7	-1.8	-1.4	-1.6	-1.9	-1.9	-1.5
Primary Biliary Cirrhosis	2.8	4.0	7.5	2.4	2.7	2.0	2.1	2.1	1.6	1.5	2.0	2.1	2.2	2.1	2.0	1.9	1.8	1.9	2.0	1.9	2.0	1.9	1.9	2.0	2.0	1.7
Medication: Atenolol	2.8	3.6	4.7	-2.1	-2.0	-1.9	-1.9	-2.1	-1.5	-1.5	-2.0	-1.4	-2.0	-2.1	-1.9	-1.7	-1.6	-2.2	-1.9	-1.9	-1.9	-2.1	-1.9	-1.8	-1.9	-2.0
Had menopause	2.8	3.5	5.9	0.6	0.9	2.2	2.4	2.0	1.5	1.6	2.3	-0.2	1.7	1.9	2.2	1.8	1.7	1.9	2.2	2.4	2.2	1.9	2.1	1.9	2.2	1.6
Medication: Ibuprofen (e.g. Nurofen)	2.8	3.6	4.9	-1.5	-1.6	-1.9	-1.8	-2.0	-2.0	-1.7	-1.9	-1.8	-2.0	-2.0	-1.9	-2.0	-1.9	-2.0	-1.9	-1.7	-1.9	-1.9	-1.9	-2.0	-1.9	-2.2
Relative age of first facial hair	2.7	5.6	21.5	-2.7	-2.9	-1.6	-1.6	-1.9	-4.1	-3.4	-1.3	-4.6	-1.9	-1.9	-1.5	-1.8	-1.1	-2.6	-1.8	-1.5	-1.6	-1.4	-1.5	-2.6	-1.6	-3.5
Medication: Ibuprofen	2.7	3.2	5.1	-1.1	-1.5	-1.8	-1.7	-1.8	-2.3	-1.9	-1.7	-2.0	-1.9	-1.8	-1.7	-1.9	-1.6	-1.9	-1.8	-1.5	-1.7	-1.6	-1.7	-2.0	-1.8	-2.2
Ever had hysterectomy (womb removed)	2.6	3.0	10.3	-2.5	-3.2	-1.5	-1.6	-1.7	-1.2	-1.1	-1.6	-1.1	-1.9	-1.7	-1.5	-1.2	-1.2	-2.1	-1.5	-1.7	-1.5	-1.9	-1.6	-1.5	-1.5	-2.0
High blood pressure (siblings)	2.6	3.7	4.9	-2.2	-2.0	-1.9	-1.9	-2.0	-1.9	-1.6	-2.1	-2.0	-1.9	-2.1	-1.9	-1.8	-1.5	-2.0	-2.0	-1.7	-1.9	-1.9	-1.9	-1.9	-1.9	-2.1
Fasting Glucose	2.5	3.0	5.6	-0.6	-0.9	-2.1	-2.2	-2.0	-0.7	-0.8	-1.8	0.4	-2.0	-2.0	-1.8	-1.6	-1.8	-1.8	-2.1	-2.4	-2.0	-1.9	-1.8	-1.8	-2.2	-1.4
Commuting to job workplace: Car/motor vehicle	2.5	2.9	4.6	-1.4	-1.6	-1.7	-1.5	-1.8	-1.7	-1.6	-1.6	-1.5	-1.9	-1.9	-1.6	-1.6	-1.5	-1.9	-1.8	-1.5	-1.6	-1.8	-1.7	-1.8	-1.7	-2.2
Cardiovascular Disease	2.4	8.1	12.2	-2.6	-1.9	-3.1	-3.1	-3.0	-1.7	-1.9	-3.2	-1.8	-3.0	-3.0	-3.1	-3.5	-3.5	-2.5	-3.0	-2.6	-3.1	-3.2	-3.1	-2.9	-3.1	-2.4
Chronic bronchitis/emphysema (father)	2.4	2.8	8.0	-2.1	-2.3	-1.3	-1.3	-1.6	-2.3	-1.5	-1.2	-2.8	-1.5	-1.6	-1.2	-1.1	-0.7	-2.1	-1.4	-1.4	-1.2	-1.3	-1.2	-1.8	-1.3	-2.3
Tense / ‘highly strung’	2.4	4.0	5.6	-2.0	-2.4	-1.9	-2.1	-2.0	-2.4	-2.4	-2.1	-2.0	-1.5	-2.0	-2.0	-2.0	-1.4	-2.1	-2.0	-1.9	-2.0	-1.7	-1.9	-2.1	-1.9	-2.2
Pack years of smoking	2.3	3.4	8.8	-0.7	-0.9	-1.7	-1.7	-1.8	-2.9	-2.4	-1.5	-3.0	-2.0	-1.7	-1.7	-1.9	-1.3	-1.9	-1.8	-1.5	-1.7	-1.3	-1.6	-2.2	-1.7	-2.2
Vascular/heart problems diagnosed by doctor	2.2	5.9	9.2	2.3	1.8	2.6	2.4	2.5	2.2	1.9	2.4	2.7	2.5	2.5	2.6	3.0	2.9	2.1	2.5	1.9	2.5	2.5	2.5	2.7	2.5	2.3
Frequency of depressed mood in last 2 weeks	2.1	2.9	6.9	-2.0	-2.6	-1.5	-1.7	-1.6	-1.9	-2.0	-1.7	-1.5	-1.3	-1.7	-1.5	-1.5	-1.1	-2.0	-1.6	-1.6	-1.6	-1.6	-1.6	-1.8	-1.5	-2.1
Worrier / anxious feelings	2.1	3.9	6.2	-2.5	-2.1	-2.0	-2.1	-2.2	-1.1	-1.5	-2.4	-1.0	-1.5	-2.2	-2.1	-2.1	-2.2	-1.8	-2.1	-2.0	-2.1	-2.1	-2.1	-1.7	-2.1	-1.6
Family relationship satisfaction	2.1	2.6	6.9	-1.3	-1.5	-1.4	-1.5	-1.4	-2.5	-2.5	-1.2	-2.6	-1.2	-1.3	-1.4	-1.6	-1.3	-1.6	-1.5	-1.3	-1.4	-1.0	-1.3	-1.8	-1.4	-2.0
Blood Red Count	2.0	19.8	43.0	-4.7	-1.9	-5.1	-5.1	-4.7	1.3	-0.8	-5.9	2.2	-3.8	-4.8	-5.0	-5.3	-6.6	-3.0	-4.7	-4.6	-5.1	-6.1	-5.3	-2.9	-5.0	-1.5
Hair/balding pattern: Pattern 3	2.0	2.9	8.5	2.9	2.9	1.3	1.4	1.5	1.3	2.1	1.4	2.8	1.7	1.5	1.3	1.9	1.8	1.3	1.3	1.0	1.3	1.5	1.3	1.4	1.3	1.5
Depression (Nagel 2018)	1.9	2.9	4.3	-1.7	-1.9	-1.5	-1.8	-1.6	-2.0	-1.9	-2.1	-1.0	-1.3	-1.6	-1.6	-1.8	-1.4	-1.9	-1.6	-1.8	-1.7	-1.7	-1.7	-1.8	-1.5	-2.0
Friendships satisfaction	1.9	2.4	4.8	2.2	1.7	1.6	1.5	1.7	0.4	0.5	1.5	0.8	2.1	1.8	1.5	1.6	1.7	1.6	1.5	1.6	1.5	2.0	1.6	1.2	1.6	1.2
Medication for cholesterol	1.9	2.9	4.7	2.2	1.7	1.8	1.7	1.9	1.0	1.3	1.7	1.4	1.9	1.9	1.7	1.7	1.8	1.6	1.8	1.5	1.7	1.9	1.7	1.6	1.8	1.4
Bipolar Disorder (2018)	1.8	2.8	7.1	-1.3	-1.6	-1.3	-1.5	-1.3	-2.7	-2.5	-1.5	-2.3	-1.3	-1.4	-1.5	-1.5	-1.1	-1.8	-1.4	-1.4	-1.4	-1.1	-1.5	-1.9	-1.3	-2.4
Alzheimer’s Disease (in mother)	1.8	2.1	3.5	-1.9	-1.6	-1.5	-1.6	-1.4	-0.6	-1.4	-1.6	-0.8	-1.5	-1.4	-1.5	-1.4	-1.5	-1.4	-1.4	-1.5	-1.5	-1.7	-1.6	-1.2	-1.4	-1.2
Stomach or abdominal pain in last month	1.8	2.3	4.6	-0.7	-1.3	-1.5	-1.6	-1.4	-2.1	-1.7	-1.7	-0.8	-1.1	-1.5	-1.6	-1.4	-0.9	-1.8	-1.6	-1.5	-1.6	-1.4	-1.6	-1.7	-1.5	-2.0
Mouth/teeth dental problems	1.8	2.8	5.8	2.2	2.3	1.4	1.4	1.6	1.8	1.2	1.3	2.4	1.8	1.6	1.4	1.8	1.4	1.8	1.4	1.2	1.4	1.6	1.4	1.7	1.4	1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	6.8	-1.4	-2.3	-1.1	-1.3	-1.2	-2.6	-2.5	-1.2	-2.3	-1.0	-1.2	-1.2	-1.1	-0.4	-1.7	-1.2	-1.2	-1.2	-0.8	-1.1	-1.7	-1.1	-2.0
Irritability	1.8	3.1	11.9	-0.7	-1.1	-1.2	-1.5	-1.3	-3.5	-2.9	-1.2	-3.4	-1.2	-1.3	-1.3	-1.9	-1.1	-1.5	-1.5	-1.0	-1.3	-0.7	-1.1	-1.9	-1.3	-2.4
Commuting to job workplace: Cycle	1.7	2.0	3.4	1.2	1.5	1.4	1.3	1.6	1.7	1.1	1.2	1.0	1.6	1.6	1.3	1.3	1.0	1.7	1.5	1.2	1.3	1.5	1.3	1.6	1.5	1.8
Pulse rate	1.6	2.7	6.0	-2.1	-1.4	-1.7	-1.6	-1.5	2.5	0.6	-2.0	2.3	-1.2	-1.6	-1.6	-1.6	-2.4	-0.5	-1.4	-1.6	-1.6	-2.3	-1.6	-0.2	-1.7	0.7
Pulse wave reflection index	1.6	1.9	12.2	-1.0	-1.1	-0.7	-0.8	-1.0	-3.0	-1.9	-0.6	-3.5	-1.2	-0.8	-0.7	-1.1	-0.6	-1.3	-0.9	-0.7	-0.8	-0.4	-0.8	-1.5	-0.7	-2.1
Gout (self-reported)	1.6	2.2	4.5	-2.1	-1.5	-1.5	-1.5	-1.5	-0.8	-0.9	-1.6	-1.3	-1.5	-1.6	-1.5	-1.7	-1.7	-1.4	-1.4	-1.4	-1.5	-1.7	-1.5	-1.3	-1.5	-1.1
Schizophrenia (2018)	1.5	3.0	4.6	1.5	0.6	2.0	1.8	2.0	1.0	1.1	2.1	0.6	1.8	2.1	2.0	1.2	1.4	2.0	2.0	2.1	1.9	2.0	2.0	1.7	2.0	1.5
Alzheimer’s Disease (including proxy)	1.5	2.1	6.5	-2.0	-2.5	-1.5	-1.3	-1.6	-0.6	-1.3	-1.6	-0.6	-1.8	-1.7	-1.4	-1.0	-1.1	-1.2	-1.5	-1.4	-1.4	-1.5	-1.5	-1.1	-1.6	-0.9
Allergy	1.5	3.4	8.7	2.5	2.9	1.6	1.7	1.7	2.2	2.0	1.7	2.0	1.7	1.7	1.6	1.0	0.7	2.1	1.7	1.8	1.6	1.3	1.7	1.9	1.6	2.3
Time employed in main current job	1.5	1.7	2.3	1.1	0.9	1.4	1.4	1.3	1.3	1.5	1.3	0.6	1.2	1.3	1.4	1.3	1.0	1.5	1.4	1.3	1.4	1.4	1.4	1.5	1.4	1.5
Glaucoma (self-reported)	1.5	1.8	3.1	0.2	0.2	1.4	1.5	1.2	1.4	1.7	1.6	-0.2	1.2	1.2	1.4	1.1	1.0	1.6	1.4	1.8	1.4	1.4	1.4	1.4	1.4	1.7
Comparative body size at age 10	1.4	3.9	11.1	-1.3	-1.5	-1.7	-1.5	-1.9	-2.6	-2.2	-1.2	-3.3	-2.5	-1.8	-1.6	-2.0	-1.6	-2.2	-1.8	-1.6	-1.6	-1.5	-1.6	-2.2	-1.7	-2.6
Hand grip strength (left)	1.3	3.4	5.8	-1.2	-1.2	-2.1	-2.2	-2.1	-1.0	-1.5	-2.2	-0.2	-2.3	-2.1	-2.1	-1.1	-1.0	-2.1	-2.1	-2.4	-2.1	-2.0	-2.1	-1.8	-2.1	-1.6
Had other major operations	1.3	1.6	8.7	-2.0	-2.9	-0.6	-0.6	-0.9	-1.9	-1.9	-0.5	-2.3	-1.2	-0.9	-0.5	-0.7	-0.3	-1.2	-0.7	-0.4	-0.5	-0.6	-0.6	-1.1	-0.6	-1.6
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.0	12.1	0.4	-1.0	-0.8	-0.8	-0.8	-3.5	-2.9	-0.8	-1.9	-0.5	-0.7	-0.9	-0.5	0.4	-1.8	-0.9	-0.8	-0.8	-0.3	-0.9	-1.8	-0.7	-2.8
Falls in the last year	1.3	1.8	7.1	-1.6	-1.3	-1.1	-1.0	-1.3	-1.8	-1.4	-0.8	-2.7	-1.4	-1.2	-1.1	-1.3	-1.0	-1.3	-1.1	-0.8	-1.1	-1.0	-1.1	-1.4	-1.1	-1.6
Mouth/teeth dental problems: Bleeding gums	1.3	1.6	3.3	1.5	1.8	1.3	1.4	1.5	0.5	0.8	1.2	0.3	1.4	1.6	1.3	0.9	1.1	1.3	1.3	1.5	1.3	1.4	1.2	1.0	1.4	0.9
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.6	-1.6	-1.6	-1.3	-1.2	-1.3	-0.0	-0.2	-1.5	-0.3	-1.6	-1.3	-1.3	-1.5	-1.5	-1.0	-1.2	-1.1	-1.3	-1.5	-1.4	-1.0	-1.3	-0.6
Medication: Allopurinol	1.3	1.7	3.1	-1.7	-1.3	-1.4	-1.4	-1.3	-0.5	-0.7	-1.5	-0.8	-1.3	-1.4	-1.4	-1.6	-1.8	-1.0	-1.3	-1.3	-1.4	-1.5	-1.4	-1.1	-1.3	-0.7
Breast cancer (self-reported)	1.3	1.6	4.2	-1.3	-2.1	-1.1	-1.0	-1.2	-1.5	-1.5	-0.9	-1.7	-1.7	-1.2	-1.1	-0.6	-0.4	-1.4	-1.1	-1.1	-1.1	-0.9	-1.1	-1.3	-1.1	-1.6
Worry (Nagel 2018)	1.2	2.5	5.6	-2.4	-2.1	-1.6	-1.8	-1.7	-0.9	-1.2	-2.1	-0.7	-1.0	-1.8	-1.6	-1.7	-1.5	-1.4	-1.6	-1.5	-1.7	-1.8	-1.7	-1.3	-1.6	-1.2
Past tobacco smoking	1.2	2.1	12.3	-0.2	0.8	0.9	1.0	0.8	3.5	2.1	0.6	2.6	1.4	0.7	1.1	1.1	0.3	1.6	1.1	0.9	1.0	0.4	1.0	1.9	0.9	2.5
Pulse wave peak to peak time	1.2	1.4	2.5	1.2	1.0	1.0	1.2	1.1	1.4	1.0	1.1	1.6	1.1	1.1	1.2	1.2	1.1	1.3	1.0	1.1	1.1	1.2	1.2	1.2	1.0	1.4
Wears glasses or contact lenses	1.2	1.3	1.9	-1.2	-0.5	-1.0	-1.2	-1.0	-1.2	-1.0	-1.3	-1.4	-1.0	-1.0	-1.2	-1.3	-1.2	-1.3	-1.0	-1.3	-1.2	-1.2	-1.3	-1.1	-1.0	-1.4
Ever taken oral contraceptive pill	1.2	1.3	4.8	-0.7	-1.7	-0.8	-0.8	-0.9	-2.0	-1.7	-0.5	-2.2	-1.3	-0.9	-0.8	-0.9	-0.5	-1.1	-1.0	-0.8	-0.8	-0.4	-0.7	-1.4	-0.9	-1.5
Risk taking	1.2	1.8	5.3	-2.1	-2.3	-1.1	-1.1	-1.3	-1.1	-1.5	-0.8	-1.7	-1.5	-1.3	-1.1	-1.2	-1.3	-1.2	-1.1	-1.0	-1.1	-1.3	-1.0	-1.1	-1.0	-1.2
Pulse wave Arterial Stiffness index	1.1	1.3	2.2	-1.2	-0.9	-1.1	-1.2	-1.1	-1.3	-0.9	-1.1	-1.5	-1.1	-1.1	-1.2	-1.2	-1.1	-1.2	-1.0	-1.1	-1.1	-1.1	-1.2	-1.1	-1.0	-1.3
Smoking status: Previous	1.1	1.6	8.1	0.1	-0.7	-0.9	-0.9	-0.8	-2.8	-1.4	-0.5	-2.3	-1.4	-0.7	-1.0	-1.0	-0.5	-1.4	-1.0	-0.8	-0.9	-0.4	-0.9	-1.7	-0.9	-2.0
Fractured/broken bones in last 5 years	1.1	1.5	2.3	1.2	1.2	1.4	1.3	1.3	-0.2	0.3	1.4	-0.4	1.3	1.4	1.4	1.2	1.5	0.9	1.3	1.4	1.3	1.5	1.3	0.9	1.4	0.4
Cholesterol lowering medication	1.1	1.7	6.8	-2.1	-1.7	-1.0	-1.1	-1.3	-0.9	-0.8	-0.9	-2.6	-1.4	-1.3	-1.0	-1.5	-1.5	-1.0	-1.0	-0.8	-1.0	-1.1	-0.9	-1.0	-1.0	-1.0
Medication for hormone replacement therapy	1.0	1.1	3.0	-1.4	-1.7	-1.0	-0.8	-1.1	-1.1	-1.2	-0.8	-0.8	-1.3	-1.1	-0.9	-0.5	-0.3	-1.3	-1.0	-1.0	-0.9	-1.0	-0.9	-1.1	-1.0	-1.2
Average weekly fortified wine intake	1.0	1.1	2.8	-0.8	-0.6	-0.9	-0.9	-1.1	-1.5	-1.3	-0.8	-1.7	-1.0	-1.0	-0.9	-0.6	-0.4	-1.4	-1.0	-1.1	-0.9	-0.8	-0.9	-1.2	-0.9	-1.5
Supplements: Glucosamine	1.0	1.3	2.4	1.5	1.2	1.1	1.1	1.1	0.9	0.9	1.1	1.5	1.1	1.1	1.2	1.4	1.3	1.0	1.1	1.0	1.1	1.1	1.1	1.1	1.1	1.0
Medication: Bendroflumethiazide	1.0	1.5	2.5	-1.6	-1.5	-1.2	-1.3	-1.3	-0.9	-0.7	-1.3	-1.5	-1.4	-1.3	-1.3	-1.3	-1.2	-1.1	-1.1	-1.0	-1.2	-1.3	-1.1	-1.2	-1.1	-1.0
Mean Putamen Volume	0.9	1.0	1.9	1.0	1.1	1.1	1.0	1.0	0.5	1.2	0.8	1.4	1.4	1.0	1.1	1.1	1.1	0.8	1.0	1.0	1.0	0.9	1.0	0.9	1.0	0.6
Schizophrenia (2014)	0.9	2.0	3.4	1.4	0.6	1.6	1.5	1.8	0.5	0.5	1.7	0.2	1.5	1.8	1.6	1.0	1.3	1.6	1.6	1.8	1.6	1.7	1.6	1.2	1.7	1.1
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	2.4	1.2	1.0	1.1	1.3	1.1	-0.7	0.0	1.3	-0.7	1.2	1.1	1.2	1.0	1.4	0.9	1.0	1.5	1.2	1.5	1.2	0.6	1.1	0.1
Ever used hormone-replacement therapy (HRT)	0.9	1.1	5.9	-1.8	-2.1	-0.5	-0.4	-0.9	-1.4	-1.1	-0.3	-2.4	-1.1	-0.9	-0.4	-0.5	-0.3	-1.1	-0.6	-0.4	-0.4	-0.6	-0.5	-1.0	-0.5	-1.4
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	2.9	-1.7	-1.1	-1.0	-1.0	-1.1	-0.1	-0.6	-1.2	-0.9	-0.7	-1.1	-1.0	-1.3	-1.4	-0.6	-0.9	-0.8	-1.0	-1.1	-0.9	-0.8	-1.0	-0.3
Vitamin and mineral supplements	0.9	1.2	4.8	-2.2	-1.7	-1.0	-1.1	-1.2	0.7	0.1	-1.0	-0.8	-1.2	-1.2	-1.0	-1.1	-1.4	-0.7	-0.9	-1.0	-1.0	-1.4	-0.9	-0.5	-1.0	-0.1
High blood pressure	0.9	2.6	5.3	-1.6	-1.3	-1.6	-1.5	-1.6	-1.7	-1.2	-1.4	-2.3	-1.7	-1.6	-1.6	-1.9	-1.8	-1.4	-1.6	-1.1	-1.6	-1.5	-1.5	-1.8	-1.6	-1.6
Medication: Levothyroxine sodium	0.9	1.4	2.7	-1.0	-0.8	-1.2	-1.0	-1.1	-1.4	-1.4	-1.0	-1.6	-0.9	-1.1	-1.2	-1.6	-1.5	-1.1	-1.2	-0.8	-1.1	-1.1	-1.1	-1.3	-1.1	-1.4
Medication: Simvastatin	0.9	1.3	3.0	-1.7	-1.3	-1.2	-1.1	-1.2	-0.3	-0.2	-1.0	-1.5	-1.5	-1.2	-1.2	-1.3	-1.4	-0.9	-1.1	-1.0	-1.1	-1.2	-1.1	-1.1	-1.1	-0.6
Depression (self-reported)	0.9	1.0	2.8	0.5	-0.7	1.3	1.1	1.1	-0.4	-0.0	1.1	-0.1	1.1	1.1	1.3	1.4	1.7	0.5	1.2	1.1	1.2	1.1	1.3	0.6	1.3	0.1
Birth weight of first child	0.9	1.6	2.6	1.3	0.7	1.4	1.3	1.4	0.6	0.4	1.5	0.2	0.9	1.5	1.4	1.4	1.5	1.3	1.3	1.3	1.4	1.6	1.4	1.1	1.3	1.2
Loud music exposure frequency	0.8	0.8	1.8	0.5	1.0	1.0	1.1	1.0	0.7	0.9	0.8	0.3	1.2	1.0	1.0	0.5	0.5	1.1	1.0	1.4	1.0	0.8	0.9	0.9	1.0	0.8
Worry too long after embarrassment	0.8	1.4	2.7	0.7	1.6	1.1	1.2	1.2	0.9	1.2	1.2	-0.5	1.6	1.2	1.2	0.5	0.5	1.5	1.1	1.4	1.1	1.4	1.2	1.2	1.1	1.3
Comparative height size at age 10	0.8	4.7	8.6	2.1	2.8	1.8	1.9	2.1	2.7	2.2	1.7	2.9	2.3	2.1	1.8	2.2	2.1	2.3	2.0	1.7	1.9	1.9	1.8	2.2	1.9	2.6
Hypertension (Self-reported)	0.8	2.2	5.3	-1.5	-1.1	-1.5	-1.4	-1.4	-1.7	-1.1	-1.3	-2.3	-1.4	-1.4	-1.5	-1.9	-1.8	-1.2	-1.4	-0.9	-1.5	-1.4	-1.4	-1.7	-1.4	-1.5
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.0	-1.0	-0.2	-0.9	-1.0	-0.9	-0.0	-0.5	-1.1	-0.4	-0.6	-0.8	-1.1	-1.3	-1.4	-0.7	-0.7	-1.0	-1.0	-1.2	-1.0	-0.7	-0.8	-0.5
Hypothyroidism (self reported)	0.7	1.7	3.0	-1.0	-1.0	-1.3	-1.1	-1.3	-1.7	-1.6	-1.0	-1.7	-1.2	-1.4	-1.2	-1.5	-1.3	-1.2	-1.4	-0.8	-1.2	-1.0	-1.1	-1.5	-1.4	-1.5
Osteoporosis (self-reported)	0.7	0.9	3.4	0.3	-0.4	0.9	0.9	0.7	-1.4	-0.8	1.2	-1.8	0.5	0.8	0.9	1.1	1.7	0.0	0.7	0.6	0.9	1.3	1.1	0.1	0.9	-0.5
Medication: Lisinopril	0.7	0.9	1.6	-1.3	-0.8	-1.0	-1.0	-1.0	-0.5	-0.5	-1.2	-0.9	-0.9	-1.0	-1.1	-1.0	-1.1	-0.8	-0.9	-0.8	-1.0	-1.1	-1.1	-0.9	-0.9	-0.8
Alcohol drinker status: Never	0.7	0.8	5.3	-0.3	0.1	0.6	0.5	0.6	2.3	1.4	0.2	1.6	0.6	0.5	0.6	0.4	-0.1	1.1	0.7	0.6	0.6	0.0	0.6	1.3	0.6	1.6
Ever smoked	0.7	1.2	9.9	0.5	-0.5	-0.2	-0.4	-0.2	-3.1	-1.9	0.0	-2.2	-0.6	-0.1	-0.4	-0.3	0.4	-1.2	-0.4	-0.5	-0.3	0.2	-0.3	-1.2	-0.2	-2.0
Bipolar Disorder (2011)	0.6	0.6	1.2	1.0	0.5	0.8	0.9	0.9	-0.5	-0.2	0.9	-0.4	0.7	0.9	0.9	0.5	0.9	0.7	0.7	1.1	0.9	1.0	0.8	0.3	0.8	-0.0
Angina	0.6	0.8	2.4	-1.3	-1.5	-0.8	-0.5	-1.1	-0.7	-0.4	-0.5	-1.5	-1.0	-1.0	-0.8	-0.9	-0.7	-0.8	-0.8	-0.5	-0.7	-0.7	-0.7	-0.8	-0.8	-0.7
Diabetes (father)	0.6	0.7	3.4	-1.9	-1.6	-0.6	-0.7	-0.9	0.4	0.2	-1.0	-0.1	-0.8	-1.0	-0.6	-0.9	-1.1	-0.4	-0.6	-0.4	-0.6	-1.2	-0.6	-0.2	-0.7	-0.3
Severe depression (siblings)	0.6	0.7	1.6	0.0	0.1	1.1	1.0	1.0	-0.2	0.1	0.8	-0.5	1.3	1.0	1.0	0.7	0.9	0.5	1.0	1.0	1.0	0.9	0.9	0.7	1.1	0.1
Relative age voice broke	0.6	0.9	4.6	0.4	-0.2	0.8	0.7	0.5	-2.1	-1.2	0.9	-2.2	0.6	0.6	0.8	0.7	1.3	-0.2	0.6	0.6	0.7	1.1	0.8	-0.2	0.7	-1.0
Headache pain in last month	0.6	1.0	1.7	-0.6	-0.9	-1.0	-1.0	-1.0	-1.3	-1.3	-1.1	-0.7	-1.0	-1.0	-1.0	-0.8	-0.6	-1.2	-1.0	-1.0	-1.0	-0.9	-1.0	-1.1	-1.0	-1.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	3.6	-1.1	-1.0	-0.9	-0.7	-0.9	-1.5	-1.4	-0.7	-1.9	-0.9	-1.0	-0.9	-1.3	-1.1	-0.9	-1.0	-0.5	-0.9	-0.8	-0.8	-1.3	-1.0	-1.3
Birth weight	0.6	1.3	3.5	1.9	1.4	1.0	1.2	1.1	0.8	0.8	1.1	1.2	0.7	1.1	1.1	1.4	1.4	1.0	1.0	1.1	1.1	1.2	1.0	1.0	1.0	0.9
Emphysema/chronic bronchitis	0.6	0.7	3.0	0.2	0.1	-0.6	-0.5	-0.6	-1.7	-0.9	-0.6	-1.6	-0.8	-0.6	-0.7	-1.1	-0.6	-0.8	-0.7	-0.5	-0.6	-0.3	-0.6	-1.1	-0.7	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.4	0.8	1.1	0.8	0.7	0.9	1.1	1.1	0.8	0.8	0.7	0.8	0.7	0.2	0.0	1.2	0.8	1.0	0.7	0.6	0.7	1.0	0.7	1.1
HbA1C	0.5	0.5	3.1	-0.0	1.8	-0.1	0.2	0.4	0.9	0.2	-1.0	1.0	0.6	0.3	-0.8	-0.3	-1.0	0.7	0.3	0.6	-0.2	-0.3	-0.9	0.8	0.3	1.0
Waist Hip Ratio (WHR)	0.5	2.1	7.8	-2.8	-0.7	-1.2	-1.3	-0.9	2.2	0.3	-2.0	1.8	-0.3	-1.0	-1.3	-1.7	-2.6	-0.0	-0.9	-0.9	-1.2	-2.0	-1.5	-0.1	-1.1	0.6
Townsend deprivation index at recruitment	0.5	0.6	1.6	-0.6	-1.1	-0.6	-0.7	-0.7	-0.8	-0.8	-0.5	-0.9	-1.0	-0.7	-0.7	-1.3	-1.2	-0.6	-0.6	-0.4	-0.7	-0.8	-0.6	-0.8	-0.6	-0.7
Multivitamins +/- minerals	0.5	0.6	4.0	2.0	1.5	0.6	0.7	0.7	-0.9	-0.2	0.7	0.6	0.8	0.7	0.6	0.7	1.0	0.2	0.5	0.6	0.6	0.9	0.5	0.1	0.6	-0.3
Nervous feelings	0.5	0.9	1.8	-1.2	-0.3	-1.0	-1.0	-1.0	-0.2	-0.7	-1.4	-0.1	-0.3	-1.1	-0.9	-1.3	-1.3	-0.6	-1.0	-0.8	-1.0	-1.1	-1.0	-0.7	-1.1	-0.5
Hearing difficulty/problems with background noise	0.5	0.9	4.8	0.6	0.4	0.9	0.9	0.7	-1.2	-0.4	1.3	-2.2	0.7	0.8	0.8	0.5	0.9	0.4	0.8	1.0	0.9	1.3	1.0	0.2	0.9	-0.2
Happiness	0.5	0.6	1.4	0.9	0.7	0.8	0.8	0.9	-0.2	-0.5	0.8	-0.4	1.2	0.9	0.8	0.2	0.5	0.9	0.7	1.1	0.8	1.1	0.8	0.5	0.8	0.4
Medication: Amlodipine	0.5	0.7	2.0	-0.8	-0.8	-0.8	-0.9	-0.9	-0.7	-0.7	-0.7	-1.4	-1.0	-0.8	-0.8	-1.2	-1.1	-0.6	-0.8	-0.7	-0.8	-0.7	-0.7	-0.9	-0.8	-0.6
Unable to work because of sickness or disability	0.5	0.7	2.1	-1.0	-1.5	-0.7	-0.7	-0.8	-1.1	-0.8	-0.7	-1.3	-0.8	-0.8	-0.7	-0.6	-0.2	-0.9	-0.7	-0.6	-0.7	-0.5	-0.7	-0.9	-0.7	-1.0
Lupus	0.4	0.6	4.5	-1.4	-1.6	-0.1	-0.1	-0.5	-1.0	-0.7	0.0	-2.1	-0.8	-0.5	-0.0	-0.5	-0.4	-0.7	-0.2	-0.0	-0.1	-0.4	-0.1	-0.5	-0.1	-1.2
Tanning	0.4	4.5	6.0	-2.2	-1.9	-2.3	-2.0	-2.4	-1.2	-1.4	-2.1	-1.2	-2.4	-2.4	-2.3	-2.2	-2.3	-2.2	-2.3	-2.3	-2.2	-2.4	-2.3	-2.1	-2.3	-1.8
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	3.9	0.5	0.0	0.1	0.2	-0.1	-1.7	-1.2	0.5	-2.0	-0.3	0.0	0.1	0.3	0.7	-0.4	-0.1	0.2	0.1	0.6	0.1	-0.5	-0.0	-1.0
Length of working week for main job	0.4	0.5	1.3	0.1	0.2	-0.9	-0.8	-0.7	0.1	-0.3	-0.9	0.4	-0.8	-0.7	-0.8	-1.1	-0.9	-0.3	-0.8	-0.6	-0.8	-0.8	-0.8	-0.6	-0.9	-0.0
Eye problems/disorders: None of the above	0.4	0.5	2.1	1.2	0.7	0.4	0.4	0.5	0.2	0.6	0.6	1.2	0.2	0.5	0.4	1.4	1.5	0.1	0.4	-0.0	0.4	0.6	0.5	0.3	0.4	0.3
Angina (self-reported)	0.4	0.5	2.3	-1.0	-1.2	-0.6	-0.3	-0.9	-0.6	-0.4	-0.2	-1.5	-0.9	-0.8	-0.6	-0.8	-0.6	-0.6	-0.7	-0.3	-0.5	-0.5	-0.5	-0.7	-0.7	-0.5
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	0.8	0.1	-0.0	0.7	0.6	0.8	0.9	0.8	0.7	0.6	0.7	0.8	0.7	0.6	0.5	0.7	0.8	0.5	0.7	0.6	0.7	0.7	0.8	0.8
Medication: Aspirin	0.4	0.6	1.8	-0.7	0.2	-0.9	-0.7	-0.8	-0.1	-0.3	-0.7	-1.0	-0.8	-0.8	-0.8	-1.3	-1.4	-0.3	-0.7	-0.4	-0.8	-0.8	-0.8	-0.8	-0.8	-0.2
Mineral and other dietary supplements	0.4	0.5	1.8	-1.3	-1.0	-0.7	-0.7	-0.7	0.1	-0.1	-0.8	-0.4	-0.6	-0.7	-0.6	-0.8	-0.9	-0.5	-0.6	-0.7	-0.7	-0.9	-0.6	-0.4	-0.7	-0.2
Medication: Aspirin	0.4	0.6	1.6	-0.6	0.4	-0.8	-0.7	-0.7	-0.5	-0.4	-0.7	-1.3	-0.7	-0.7	-0.8	-1.3	-1.3	-0.4	-0.7	-0.4	-0.8	-0.7	-0.7	-0.9	-0.7	-0.4
Medication: Blood pressure	0.4	0.7	1.6	-1.2	-0.7	-0.8	-0.9	-0.9	-0.5	-0.4	-0.9	-1.3	-0.8	-0.9	-0.8	-1.1	-1.2	-0.5	-0.9	-0.4	-0.8	-0.9	-0.8	-0.7	-0.9	-0.6
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.3	1.1	1.0	0.6	0.7	0.7	0.8	0.8	0.7	0.9	0.4	0.7	0.6	0.6	0.5	0.9	0.6	0.7	0.6	0.7	0.6	0.7	0.6	0.9
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.1	-1.4	-1.5	-0.4	-0.7	-0.6	-0.7	-0.6	-0.6	-0.8	-0.5	-0.6	-0.4	-0.4	-0.4	-0.7	-0.4	-0.4	-0.4	-0.7	-0.4	-0.5	-0.4	-0.8
Alzheimer’s Disease (in father)	0.3	0.3	0.7	-0.6	-0.8	-0.7	-0.5	-0.7	0.0	-0.1	-0.7	0.2	-0.8	-0.8	-0.6	-0.5	-0.6	-0.4	-0.8	-0.4	-0.6	-0.8	-0.7	-0.4	-0.8	-0.2
Allergy or Eczema	0.3	0.8	2.8	0.4	-0.3	0.9	0.9	0.8	0.2	0.7	0.9	0.5	0.7	0.9	0.9	1.7	1.6	0.5	0.8	0.7	0.9	1.1	0.8	0.7	0.9	0.4
Hayfever, allergic rhinitis or eczema	0.3	0.7	3.3	0.2	-0.6	0.8	0.7	0.8	0.2	0.5	0.7	0.6	0.8	0.8	0.7	1.7	1.8	0.3	0.7	0.4	0.7	1.0	0.7	0.7	0.7	0.4
Hair/balding pattern: Pattern 4	0.3	0.7	1.9	-0.4	-1.2	-0.9	-0.9	-0.9	0.1	-0.4	-0.8	0.4	-1.4	-0.8	-0.9	-0.7	-0.9	-0.7	-0.9	-0.8	-0.9	-1.0	-0.9	-0.5	-0.9	-0.4
Blood clot in the leg (DVT)	0.3	0.4	2.0	-1.3	-1.4	-0.3	-0.6	-0.5	-0.5	-0.5	-0.5	-0.7	-0.4	-0.5	-0.3	-0.4	-0.4	-0.6	-0.3	-0.3	-0.3	-0.6	-0.3	-0.4	-0.3	-0.7
Heart disease (mother)	0.3	0.3	1.4	1.2	0.8	0.5	0.6	0.5	-0.2	0.3	0.6	-0.3	0.4	0.5	0.6	0.6	0.7	0.5	0.5	0.7	0.5	0.9	0.5	0.3	0.5	0.2
Eye problems/disorders: Cataract	0.3	0.3	1.7	0.9	1.3	0.4	0.4	0.5	0.5	-0.0	0.3	0.6	0.8	0.5	0.4	-0.3	-0.3	0.6	0.4	0.7	0.4	0.3	0.3	0.5	0.4	0.3
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	3.5	-1.9	-1.7	0.2	0.2	-0.2	0.0	0.5	0.4	-1.3	-0.3	-0.2	0.2	-0.2	-0.2	-0.2	0.2	0.4	0.2	-0.3	0.2	0.0	0.2	-0.3
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.2	-0.5	-0.1	-0.6	-0.7	-0.6	0.6	-0.0	-0.7	0.6	-0.6	-0.6	-0.6	-0.7	-1.1	-0.2	-0.6	-0.5	-0.7	-0.8	-0.7	-0.2	-0.7	-0.0
Medication: Atorvastatin	0.3	0.3	1.2	-0.9	-0.5	-0.4	-0.3	-0.6	-0.2	0.1	-0.4	-1.1	-0.6	-0.6	-0.4	-0.8	-1.0	-0.3	-0.4	-0.1	-0.4	-0.7	-0.4	-0.3	-0.4	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.4	1.0	0.3	-0.5	0.7	0.4	0.7	-0.9	-0.7	0.7	-1.0	0.6	0.8	0.7	0.0	0.4	0.4	0.7	0.8	0.6	0.9	0.6	0.1	0.8	-0.3
Triglycerides	0.2	0.4	1.9	-0.4	0.2	-0.3	-0.4	-0.2	1.4	0.9	-0.6	1.4	-0.2	-0.3	-0.3	-0.7	-1.2	0.3	-0.2	-0.3	-0.3	-0.7	-0.3	0.4	-0.3	0.6
Sensitivity / hurt feelings	0.2	0.3	1.6	-1.2	-0.7	-0.3	-0.3	-0.3	-0.6	-0.3	-0.5	-1.3	-0.0	-0.4	-0.3	-0.9	-0.7	-0.3	-0.3	0.1	-0.3	-0.5	-0.3	-0.5	-0.3	-0.6
Supplements: Zinc	0.2	0.2	1.4	0.6	0.9	0.0	-0.0	0.2	-1.2	-0.7	0.1	-1.0	0.2	0.3	-0.1	-0.2	0.1	-0.1	0.0	0.1	-0.1	0.4	-0.1	-0.4	0.1	-0.5
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.3	1.1	0.5	0.2	0.1	0.2	-1.0	-1.1	0.2	-0.0	0.4	0.2	0.2	0.5	0.8	-0.1	0.1	0.2	0.1	0.5	0.2	-0.2	0.2	-0.4
Number of incorrect matches in round	0.2	0.3	1.6	1.2	0.1	0.1	0.1	0.1	-1.1	-0.9	0.5	-0.9	-0.2	0.2	0.1	0.8	1.3	-0.1	0.0	-0.1	0.1	0.9	0.2	-0.4	0.1	-0.2
Illnesses of father: Heart disease	0.2	0.2	1.7	-0.5	-0.4	-0.3	-0.3	-0.4	-0.6	-1.0	-0.1	-1.3	-0.5	-0.3	-0.2	-0.5	-0.3	-0.3	-0.4	-0.1	-0.3	-0.2	-0.3	-0.4	-0.3	-0.5
Handedness (chirality/laterality): Left-handed	0.2	0.3	2.0	0.6	1.4	0.4	0.4	0.5	0.3	0.2	0.6	-0.2	0.6	0.5	0.4	0.3	0.2	0.7	0.4	0.4	0.4	0.6	0.6	0.3	0.4	0.6
Hearing aid user	0.2	0.2	1.0	-1.0	-0.4	-0.4	-0.4	-0.5	0.1	-0.2	-0.4	-0.5	-0.4	-0.5	-0.4	-0.7	-0.7	-0.3	-0.4	-0.4	-0.4	-0.7	-0.5	-0.2	-0.4	-0.2
Eye problems/disorders: Glaucoma	0.2	0.2	1.2	-1.0	-0.8	0.1	0.1	-0.2	0.5	0.0	0.3	-1.1	0.0	-0.2	0.2	-0.3	-0.4	0.4	0.1	0.5	0.1	0.0	0.2	0.2	0.1	0.5
Illnesses of father: High blood pressure	0.2	0.2	1.4	-0.8	-0.3	-0.3	-0.5	-0.3	0.3	0.5	-0.6	-0.3	-0.2	-0.3	-0.5	-0.9	-1.2	0.2	-0.2	-0.1	-0.5	-0.5	-0.5	-0.0	-0.3	0.1
Ever had prostate specific antigen (PSA) test	0.2	0.3	1.2	0.5	0.3	0.4	0.5	0.4	0.8	1.1	0.2	1.1	0.4	0.3	0.5	0.6	0.5	0.4	0.4	0.3	0.4	0.4	0.4	0.5	0.3	0.5
Ovarian Cancer	0.1	0.1	0.4	0.7	0.3	0.3	0.3	0.3	-0.3	-0.1	0.4	-0.0	0.4	0.3	0.2	0.3	0.3	0.1	0.3	0.2	0.3	0.4	0.3	0.2	0.4	0.0
LDL Cholesterol	0.1	0.1	0.5	0.2	-0.1	0.1	0.1	0.2	0.7	0.5	0.2	0.4	-0.2	0.2	0.2	0.2	-0.1	0.3	0.2	0.1	0.1	0.1	0.0	0.3	0.2	0.5
Rheumatoid Arthritis	0.1	0.1	0.3	0.5	0.5	0.3	0.3	0.3	-0.5	0.0	0.5	-0.1	0.5	0.3	0.4	0.3	0.5	0.1	0.3	0.4	0.3	0.4	0.4	0.1	0.3	-0.2
Blood Platelet Count	0.1	0.8	6.6	-0.9	-0.4	0.9	0.9	0.4	-0.6	-0.3	1.2	-2.6	-0.2	0.5	0.8	0.3	0.8	0.3	0.7	1.1	0.9	0.6	0.8	0.4	0.8	-0.0
Height	0.1	1.8	4.2	0.3	1.6	1.2	1.4	1.4	1.5	0.8	0.8	1.7	1.8	1.2	1.3	2.0	2.1	1.1	1.2	1.2	1.3	1.1	1.2	1.3	1.2	1.2
Hearing difficulty/problems: Yes	0.1	0.2	2.3	-0.3	-0.4	0.0	-0.0	-0.1	-0.8	-0.4	0.2	-1.5	-0.0	-0.1	-0.0	-0.3	-0.2	-0.1	-0.0	0.0	0.0	0.2	0.2	-0.3	0.0	-0.2
Sitting height	0.1	0.5	1.5	-1.1	-1.2	-0.8	-0.6	-0.9	0.7	0.1	-0.7	0.4	-1.2	-1.0	-0.6	0.1	-0.2	-0.5	-0.7	-0.7	-0.6	-0.7	-0.6	-0.3	-0.8	0.1
High blood pressure (mother)	0.1	0.1	0.4	-0.2	0.5	0.2	0.2	0.2	0.4	0.6	0.1	-0.4	0.2	0.2	0.1	-0.3	-0.4	0.5	0.2	0.6	0.2	0.0	0.2	0.2	0.2	0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	1.2	0.2	0.1	0.3	0.2	0.4	0.7	0.4	0.0	1.1	0.6	0.4	0.3	0.5	0.5	0.2	0.4	0.1	0.3	0.2	0.1	0.6	0.4	0.4
Standing height	0.1	0.5	1.2	0.1	1.0	0.6	0.6	0.7	0.9	0.3	0.3	1.1	0.9	0.6	0.6	0.9	0.9	0.8	0.6	0.7	0.6	0.6	0.6	0.7	0.5	0.8
Migraine (self-reported)	0.1	0.1	0.5	-0.7	-0.6	0.0	-0.1	-0.0	-0.2	-0.1	-0.2	-0.4	-0.1	-0.1	0.1	-0.3	-0.2	-0.0	0.0	0.3	0.0	-0.3	-0.0	-0.1	0.0	-0.2
Suffer from ‘nerves’	0.1	0.2	0.4	-0.3	-0.4	-0.4	-0.5	-0.5	-0.6	-0.5	-0.6	-0.4	-0.1	-0.5	-0.3	-0.2	0.1	-0.4	-0.5	-0.4	-0.4	-0.2	-0.3	-0.4	-0.4	-0.3
Supplements: Vitamin C	0.1	0.2	1.3	1.0	1.1	0.1	0.2	0.3	-0.4	-0.3	0.2	0.3	0.3	0.3	0.2	0.4	0.7	-0.0	0.1	0.1	0.1	0.4	0.1	-0.1	0.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	1.0	-0.0	-0.6	0.3	0.4	0.3	0.4	-0.2	0.2	0.8	0.3	0.2	0.4	0.8	1.0	0.4	0.2	0.4	0.4	0.4	0.5	0.4	0.2	0.4
Illnesses of father: None of the above (group 1)	0.1	0.2	1.8	0.5	0.3	0.1	0.2	0.3	0.7	0.3	-0.0	1.3	0.3	0.3	0.1	0.2	0.2	0.3	0.3	0.1	0.2	0.0	0.0	0.3	0.2	0.5
High cholesterol (Self-reported)	0.1	0.2	1.3	-0.4	0.1	-0.3	-0.1	-0.3	1.1	1.1	-0.2	0.4	-0.5	-0.2	-0.3	-0.2	-0.5	0.2	-0.2	-0.1	-0.2	-0.4	-0.3	0.2	-0.2	0.6
Heart disease (siblings)	0.1	0.1	0.2	0.1	-0.2	-0.3	-0.1	-0.4	-0.5	-0.4	-0.1	-0.5	-0.2	-0.4	-0.2	-0.2	-0.1	-0.3	-0.3	-0.0	-0.2	-0.1	-0.1	-0.4	-0.3	-0.3
Hair Pigment	0.0	0.3	1.8	-0.9	-0.9	0.3	0.4	0.2	-0.9	-0.3	0.4	-1.3	-0.1	0.2	0.3	0.0	0.2	-0.4	0.4	0.2	0.4	-0.0	0.2	-0.5	0.5	-0.6
Serious illness, injury or assault to yourself	0.0	0.1	0.4	0.1	-0.5	0.2	0.1	0.1	-0.3	-0.2	0.2	-0.6	-0.1	0.2	0.1	0.3	0.3	0.1	0.1	0.2	0.1	0.4	0.1	0.1	0.2	-0.0

Hub : Genes

UBA7

Models

Trait associations