Best TWAS P=6.34e-13 · Best GWAS P=2.63e-13 conditioned to 0.0736
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RSPO3 | 0.02 | 0.02 | blup | 60 | 0.02 | 2.8e-04 | -5.6 | -7.1 | 1.2e-12 | 0.86 | 0.09 | 0.72 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | RSPO3 | 0.02 | 0.03 | blup | 60 | 0.02 | 1.3e-03 | -7.1 | -7.2 | 6.3e-13 | 0.92 | 0.01 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RSPO3 | 0.06 | 0.02 | blup | 60 | 0.04 | 9.3e-05 | -7.1 | -5.8 | 5.9e-09 | 0.82 | 0.01 | 0.97 | FALSE |