[Hub]/) : Traits : Fractured/broken bones in last 5 years :

chr12:14,337,924-15,812,575

Best TWAS P=7.66e-08 · Best GWAS P=1.06e-07 conditioned to 0.356

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ARHGDIB 0.10 0.06 enet 10 0.08 5.4e-05 5.3 -5.3 9.8e-08 -0.97 0.02 0.97 FALSE
2 METSIM Adipose MGP 0.04 0.04 bslmm 359 0.04 6.2e-07 4.7 -5.1 3.0e-07 -0.82 0.17 0.82 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma ERP27 0.04 0.09 lasso 5 0.09 2.8e-17 5.3 -5.3 1.0e-07 -0.98 0.01 0.99 FALSE
4 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma ERP27 0.09 0.14 lasso 2 0.12 1.7e-06 5.2 -5.3 1.4e-07 -0.95 0.01 0.98 FALSE
5 The Cancer Genome Atlas Glioblastoma Multiforme ERP27 0.18 0.07 blup 76 0.11 2.7e-04 5.3 -5.3 1.4e-07 -0.89 0.02 0.92 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ERP27 0.10 0.18 lasso 6 0.18 1.2e-19 5.3 -5.2 1.7e-07 -0.95 0.02 0.98 FALSE
7 The Cancer Genome Atlas Lung Adenocarcinoma ERP27 0.15 0.28 lasso 6 0.28 8.3e-33 5.2 -5.3 1.2e-07 -0.97 0.01 0.99 FALSE
8 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma ERP27 0.04 0.05 enet 12 0.04 1.0e-03 5.1 -5.3 9.3e-08 -0.96 0.02 0.94 FALSE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma ERP27 0.14 0.12 lasso 5 0.11 2.9e-05 5.3 -5.3 1.5e-07 -0.97 0.01 0.98 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma ERP27 0.13 0.14 lasso 5 0.13 8.3e-14 5.0 -5.4 7.7e-08 -0.92 0.02 0.98 TRUE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors ERP27 0.10 0.05 lasso 1 0.08 8.9e-04 5.3 -5.3 1.2e-07 -0.98 0.02 0.96 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma ERP27 0.37 0.54 enet 18 0.55 2.3e-63 5.3 -5.2 2.0e-07 -0.97 0.01 0.99 FALSE