TWAS hub - ARHGDIB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0980	0.0370	1.1e-04	0.009	NA	0.012	NA	0.006	5.5e-02	NA	3.6e-02	NA	1.0e-01
2	GTEx	Artery Aorta	0.1040	0.0430	9.6e-04	0.059	NA	0.076	NA	0.068	3.4e-04	NA	5.4e-05	NA	1.3e-04
3	GTEx	Artery Tibial	0.0654	0.0288	1.3e-03	0.015	NA	0.009	NA	0.022	2.1e-02	NA	6.0e-02	NA	6.8e-03
4	GTEx	Esophagus Mucosa	0.1780	0.0490	5.2e-07	0.137	NA	0.145	NA	0.140	2.0e-09	NA	6.6e-10	NA	1.4e-09
5	GTEx	Skin Sun Exposed Lower leg	0.0750	0.0280	8.0e-04	0.044	NA	0.052	NA	0.044	1.5e-04	NA	4.2e-05	NA	1.4e-04
6	GTEx	Testis	0.1300	0.0610	5.4e-03	0.020	NA	0.058	NA	0.055	4.5e-02	NA	1.4e-03	NA	1.8e-03
7	GTEx	Thyroid	0.1220	0.0480	1.6e-04	0.028	NA	0.022	NA	0.010	2.9e-03	NA	7.4e-03	NA	5.5e-02
8	METSIM	Adipose	0.0290	0.0142	9.1e-03	0.002	0.011	0.002	0.009	0.001	1.3e-01	0.0069	1.5e-01	0.012	1.9e-01
9	NTR	Blood	0.0110	0.0057	9.0e-03	0.003	0.002	0.001	0.002	0.002	2.9e-02	0.0560	1.5e-01	0.069	7.0e-02
10	TCGA	Head and Neck Squamous Cell Carcinoma	0.0387	0.0217	5.5e-03	0.023	0.010	0.017	NA	0.015	1.1e-03	0.0210	4.1e-03	NA	7.4e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Hand grip strength (left)	21.1	55.5	104.4	8.2	9.8	10.2	2.0	3.8	5.3	9.2	7.3	10.2	-0.2
Hand grip strength (right)	19.3	52.5	106.1	7.8	9.5	9.4	3.1	4.3	5.2	8.8	6.8	10.3	1.1
Fractured/broken bones in last 5 years	9.1	11.8	28.4	-4.2	-5.3	-4.4	0.1	-1.1	-1.6	-4.5	-3.0	-4.3	0.4
Supplements: Glucosamine	7.3	9.5	22.0	-2.7	-4.4	-3.7	-1.6	-3.2	-1.1	-3.3	-2.4	-4.7	-1.5
Supplements: Calcium	5.4	5.9	12.0	-2.6	-3.2	-3.5	-1.4	-2.3	-1.6	-2.8	-1.5	-2.9	-1.5
Other serious medical condition/disability diagnosed by doctor	4.8	6.2	9.5	-2.3	-2.2	-3.0	-2.4	-2.8	-2.6	-2.9	-0.3	-3.1	-2.2
Supplements: Vitamin C	4.5	5.3	15.2	-1.5	-2.0	-2.9	-2.2	-3.0	-1.9	-2.0	-0.5	-3.9	-1.5
Medication: Atenolol	3.9	4.8	12.6	-3.6	-2.5	-2.9	-0.8	-1.1	-1.4	-2.4	-1.7	-2.9	-0.1
Heel T-Score	3.6	28.3	60.4	5.5	6.4	7.2	2.2	4.0	4.4	7.8	4.8	5.9	0.7
Impedance of arm (left)	3.1	14.5	27.4	-2.9	-5.2	-3.6	-2.7	-3.4	-3.5	-3.5	-4.2	-5.1	-3.2
Hair/balding pattern: Pattern 2	3.0	3.8	15.3	3.9	2.7	1.8	-0.4	0.2	-0.3	1.8	1.0	2.6	-0.8
Primary Biliary Cirrhosis	2.8	3.9	12.4	1.8	1.1	0.4	-3.5	-2.4	1.3	0.7	2.1	0.3	-3.1
Arm fat-free mass (left)	2.8	14.2	28.9	3.2	5.4	4.1	2.7	3.5	2.6	3.1	4.6	5.0	2.3
Reaction Time	2.7	5.2	17.1	-0.1	2.4	2.5	2.7	4.1	1.6	2.0	0.5	1.5	2.5
Medication: Ibuprofen (e.g. Nurofen)	2.7	3.4	11.2	-1.9	-1.7	-1.6	-1.4	-2.2	-1.1	-1.9	0.6	-3.3	-1.4
Arm predicted mass (right)	2.7	13.9	27.7	3.2	5.3	3.9	3.1	3.8	2.4	2.9	4.3	4.9	2.6
Handedness (chirality/laterality): Left-handed	2.7	3.2	5.9	-0.7	-2.4	-2.1	-2.0	-2.4	0.1	-1.7	-1.0	-2.4	-1.5
Arm fat-free mass (right)	2.6	13.4	27.2	3.0	5.2	3.9	3.0	3.8	2.4	2.6	4.2	4.7	2.6
Osteoarthritis (self-reported)	2.6	3.4	9.9	-0.9	-2.8	-1.6	-1.2	-1.4	0.2	-2.7	-1.2	-3.1	-0.8
Impedance of arm (right)	2.5	11.6	21.8	-2.3	-4.7	-3.0	-2.8	-3.5	-3.0	-2.8	-3.4	-4.6	-3.1
Number of self-reported non-cancer illnesses	2.5	4.3	9.9	-2.2	-2.4	-1.5	1.2	0.8	-1.5	-2.1	-3.1	-2.8	1.9
Rheumatoid Arthritis	2.4	3.3	7.9	1.2	2.8	2.5	1.0	1.6	1.3	1.4	1.4	2.6	0.9
Qualifications: O levels/GCSEs or equivalent	2.4	3.8	6.5	-1.8	-1.9	-2.2	-2.1	-2.4	-2.1	-2.5	-1.0	-1.5	-1.4
Migraine (self-reported)	2.4	3.0	4.7	-2.1	-1.2	-0.8	-2.2	-2.1	-2.1	-1.4	-0.5	-1.7	-2.1
Heart disease (siblings)	2.4	2.9	8.8	-0.6	-0.5	-0.3	-3.0	-2.8	-1.7	0.4	0.2	-2.0	-2.3
Arm predicted mass (left)	2.4	12.3	24.8	2.9	5.0	3.7	2.8	3.4	2.2	2.8	4.2	4.7	2.3
Number of treatments/medications taken	2.3	4.2	11.3	-3.2	-1.6	-2.4	-0.4	-1.1	-1.4	-2.3	-1.8	-3.4	0.5
Trunk fat-free mass	2.2	12.4	24.5	3.3	4.9	3.8	2.9	3.4	1.3	2.5	4.1	5.0	2.3
Mean time to correctly identify matches	2.2	4.2	15.7	-0.1	1.4	1.9	2.7	4.0	1.1	1.7	-0.6	0.4	2.9
Long-standing illness, disability or infirmity	2.2	3.4	10.8	-3.3	-1.6	-1.9	-0.8	-0.3	-1.4	-2.1	-1.4	-2.9	0.6
Trunk predicted mass	2.1	12.1	24.1	3.3	4.8	3.8	2.9	3.4	1.2	2.4	4.0	4.9	2.3
Had menopause	2.0	2.5	5.7	-0.2	-2.0	-1.5	1.4	1.0	1.2	-1.0	-2.1	-1.6	2.4
Neck or shoulder pain in last month	2.0	2.8	8.6	-2.7	-1.2	-2.0	-1.0	-1.3	-0.4	-1.8	0.2	-2.9	-0.4
Mineral and other dietary supplements	2.0	2.6	7.0	0.8	1.9	2.1	1.8	2.6	0.3	0.6	1.1	2.3	1.0
Whole body water mass	2.0	11.5	22.8	3.1	4.8	3.6	2.8	3.3	1.7	2.3	3.9	4.7	2.2
Body Mass Index (BMI) (2010)	1.9	2.6	6.8	1.3	2.6	1.4	0.6	0.9	1.9	1.7	2.1	1.6	0.8
Medication: Ibuprofen	1.9	2.2	7.7	-1.6	-1.2	-1.3	-1.1	-1.7	-1.0	-1.5	0.4	-2.8	-1.2
Whole body fat-free mass	1.9	10.9	21.9	3.0	4.7	3.5	2.6	3.2	1.6	2.2	3.9	4.6	2.1
Basal metabolic rate	1.9	10.3	20.1	2.6	4.5	3.4	2.7	3.3	2.1	2.3	3.6	4.4	2.2
Heel bone mineral density (BMD) T-score, automated (left)	1.8	4.0	11.4	1.4	3.4	3.1	0.7	1.6	0.1	2.6	0.8	2.3	1.2
Impedance of whole body	1.8	9.2	18.9	-2.5	-4.2	-2.3	-2.2	-2.7	-2.7	-2.5	-3.3	-4.4	-2.8
Ever used hormone-replacement therapy (HRT)	1.7	2.1	7.3	-0.2	-1.6	-1.9	1.2	0.2	-0.6	-1.1	-2.7	-1.5	1.5
Average weekly fortified wine intake	1.7	2.0	7.8	-1.9	-1.0	-1.0	-1.2	-1.4	-2.8	-0.6	-0.6	-0.9	-1.0
Relative age voice broke	1.7	2.7	5.8	-0.8	-2.4	-2.1	1.1	-0.5	1.4	-0.9	-2.4	-2.1	1.2
Ever unenthusiastic/disinterested for a whole week	1.7	2.0	4.9	0.0	-0.9	-1.1	-1.8	-1.8	-1.2	-0.7	0.7	-2.1	-2.2
Heart attack	1.7	2.2	5.5	-1.8	-0.9	-1.6	-1.2	-0.8	-2.2	-2.4	-0.7	-1.6	0.0
Emphysema/chronic bronchitis	1.7	1.9	8.0	-2.8	-0.8	-0.0	-0.5	0.3	-0.9	-1.9	-1.0	-1.9	-0.8
Osteoporosis (self-reported)	1.7	2.1	4.6	-2.1	-1.9	-1.4	1.3	0.4	-0.1	-1.9	-1.9	-1.2	0.7
Medication: Atorvastatin	1.7	2.1	3.6	-0.9	-1.6	-1.7	-1.5	-1.6	-1.7	-1.9	-1.3	-1.2	-0.6
Severe depression (siblings)	1.6	1.8	6.4	-2.4	-1.0	-0.7	0.7	0.8	-0.8	-0.8	-2.5	-0.8	0.7
Taking other prescription medications	1.6	2.4	5.3	-1.4	-1.6	-1.7	-0.4	-1.1	-2.0	-1.8	-1.5	-2.3	0.5
Medication: Cholesterol lowering	1.6	2.5	5.5	-2.0	-1.9	-2.4	-0.7	-0.9	-0.9	-2.3	-1.2	-1.5	1.0
Medication: Lansoprazole	1.6	1.8	8.8	-0.7	-2.0	-1.1	-0.5	-0.3	-0.7	-0.7	-1.2	-3.0	-0.5
Heart attack/myocardial infarction (self-reported)	1.6	2.0	5.0	-1.7	-0.9	-1.4	-1.2	-0.8	-2.2	-2.2	-0.7	-1.5	-0.0
Alzheimer’s Disease (in father)	1.5	1.7	3.4	-0.7	-1.6	-1.0	1.6	1.4	0.5	-1.6	-1.4	-0.5	1.8
Crohns Disease (2012)	1.5	2.5	8.3	2.9	1.6	1.7	-1.2	-0.7	-0.6	1.8	1.2	0.3	-2.0
Angina	1.5	2.0	8.2	-0.1	-0.2	-1.1	-2.9	-2.2	-0.1	0.3	1.5	-1.2	-1.3
Sitting height	1.5	10.6	27.5	4.1	3.5	4.0	2.6	3.0	1.1	2.5	2.9	5.2	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	4.1	0.7	1.2	0.2	1.5	1.6	1.3	1.1	-0.7	2.0	2.0
Mean Putamen Volume	1.4	1.6	3.7	-1.3	-1.6	-1.9	0.4	-0.3	-1.9	-1.3	0.3	-1.4	-0.3
Mouth/teeth dental problems	1.4	2.2	3.9	0.7	1.7	1.8	1.8	2.0	0.6	1.1	0.6	2.0	1.6
Tense / ‘highly strung’	1.4	2.3	6.1	-1.9	-2.0	-0.8	1.1	0.6	-1.1	-2.5	-0.6	-2.0	0.8
Loud music exposure frequency	1.4	1.5	5.4	0.3	0.3	-0.3	1.6	2.3	-1.3	-1.4	-0.5	-0.2	1.6
Angina (self-reported)	1.4	1.8	7.7	0.3	0.2	-0.8	-2.8	-2.0	-0.1	0.4	1.7	-0.9	-1.3
Forced expiratory volume in 1-second (FEV1), predicted	1.4	3.0	7.8	2.8	1.9	2.1	1.4	1.7	0.3	1.5	1.4	2.2	0.5
Leg fat-free mass (right)	1.4	7.2	15.2	2.6	3.9	2.8	1.9	2.6	1.8	1.7	3.1	3.9	1.5
High cholesterol (Self-reported)	1.4	2.6	8.5	-1.6	-1.4	-1.0	1.1	1.5	0.2	-1.4	-2.3	-0.9	2.9
Fasting Glucose	1.3	1.5	3.5	1.7	1.9	0.9	-0.7	0.6	1.4	1.3	1.7	0.8	-0.6
Had other major operations	1.3	1.5	3.7	-1.9	-1.3	-1.9	-0.5	-1.0	-1.4	-0.4	-0.8	-1.5	0.2
Qualifications: None of the above	1.3	2.7	14.0	1.2	1.1	1.5	1.0	1.8	3.7	1.2	1.2	0.4	1.2
Time employed in main current job	1.3	1.5	3.2	1.5	1.1	1.3	0.6	0.2	1.8	1.8	0.6	0.7	1.4
Hair/balding pattern: Pattern 4	1.3	3.1	8.2	-2.9	-2.4	-1.6	1.0	0.7	1.8	-1.1	-2.1	-1.7	1.3
Medication: Amlodipine	1.3	1.8	4.5	-0.8	-1.9	-2.1	-0.9	-1.0	-1.0	-1.9	-0.2	-1.6	0.2
Commuting to job workplace: Walk	1.3	1.4	2.5	1.2	-1.4	-1.5	-1.0	-1.1	-0.4	-1.6	-0.7	-0.7	-1.5
Leg predicted mass (right)	1.3	7.2	15.2	2.6	3.9	2.8	1.8	2.6	1.7	1.7	3.1	3.9	1.4
Number of operations (self-reported)	1.3	1.9	4.2	-2.1	-1.4	-1.4	-0.4	-0.8	-1.9	-1.2	-1.6	-1.5	0.3
Schizophrenia vs Biploar Disorder	1.2	1.6	6.5	1.4	0.1	1.1	-0.6	-0.2	2.5	1.0	2.0	-0.5	-0.7
Leg fat-free mass (left)	1.2	6.1	13.2	2.1	3.6	2.6	1.9	2.4	1.6	1.4	3.1	3.5	1.4
Chronic bronchitis/emphysema (father)	1.2	1.4	2.6	-1.1	-1.6	-1.0	-1.3	-1.5	-0.8	-1.5	0.0	-1.5	-0.5
Leg predicted mass (left)	1.2	6.3	14.1	2.1	3.8	2.6	1.8	2.4	1.5	1.5	3.2	3.5	1.4
Waist circumference	1.2	4.5	9.6	-0.3	2.3	1.4	2.3	2.7	3.1	2.0	0.9	1.9	2.7
Hair/balding pattern: Pattern 3	1.2	1.8	7.6	-2.7	-1.0	-1.2	-0.5	-1.0	-1.4	-1.6	-0.2	-1.4	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	4.4	1.8	0.3	1.1	0.8	0.3	1.1	2.1	0.7	1.4	0.6
Mouth/teeth dental problems: Loose teeth	1.2	1.4	3.7	-0.1	0.2	0.6	1.9	1.8	1.4	-0.0	-1.3	1.1	1.2
Alcohol drinker status: Previous	1.2	1.4	4.0	-0.6	-1.8	-1.0	0.8	-0.0	-1.3	-2.0	-1.7	-0.4	0.4
Coronary Artery Disease (CAD)	1.1	1.3	3.9	0.7	-1.3	-1.5	1.1	0.7	-0.1	-0.7	-2.0	-0.6	1.5
Vitamin and mineral supplements	1.1	1.4	3.3	0.6	1.0	1.7	1.4	1.8	0.8	-0.2	0.4	1.3	1.5
Supplements: Zinc	1.1	1.1	2.5	-0.1	-0.6	-1.4	-1.1	-1.6	-1.3	-1.3	0.2	-0.8	-1.2
Weight	1.1	5.6	9.6	0.6	2.9	1.9	2.6	3.1	2.6	1.6	2.0	2.5	2.7
Hip circumference	1.1	4.6	10.8	0.4	2.0	1.2	2.9	3.3	2.3	1.3	0.6	2.2	3.0
Alcohol intake versus 10 years previously	1.1	1.6	3.9	0.3	1.1	1.3	-1.9	-1.5	-0.2	0.2	1.8	0.6	-2.0
Pulse rate	1.1	1.8	5.4	-2.3	-2.3	-1.2	0.9	-0.4	0.1	-1.0	-1.1	-1.4	0.7
Qualifications: A levels/AS levels or equivalent	1.1	2.5	7.0	-0.6	-0.6	-1.7	-2.4	-2.6	-1.4	-0.7	-0.1	-0.1	-2.3
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	4.8	1.8	1.3	1.3	-0.6	-0.2	0.0	2.2	1.5	1.0	-1.7
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	4.3	-0.4	0.7	-0.0	-1.6	-1.1	-1.6	1.0	1.1	0.2	-2.1
Knee pain experienced in last month	1.1	1.8	4.6	-0.0	1.5	1.5	0.2	0.9	2.1	2.1	1.5	0.8	0.6
Medication: Lisinopril	1.1	1.5	6.2	0.0	-0.1	0.2	1.6	1.6	2.5	0.4	-0.7	0.4	1.6
Leg fat percentage (left)	1.1	4.0	12.5	-2.2	0.5	0.2	2.3	2.6	3.5	1.2	-0.6	-0.4	2.8
Age started oral contraceptive pill	1.1	1.4	6.5	0.3	-1.7	-1.3	0.5	-0.5	-0.2	-0.8	-2.5	-0.6	1.0
Leg fat mass (left)	1.1	4.2	11.8	-1.0	1.7	1.0	2.5	2.8	3.4	1.5	0.7	0.9	2.8
Crohns Disease (2017)	1.0	2.1	5.3	2.1	1.8	2.3	-0.4	-0.1	-0.3	1.6	-0.0	1.4	-1.9
Ovarian Cancer	1.0	1.3	3.6	-1.1	-0.8	-1.0	-1.5	-1.9	-0.7	-0.7	0.3	-1.5	-0.9
Medication: Co-codamol	1.0	1.2	4.3	-1.7	-1.2	-0.4	-0.4	0.1	-0.2	-1.4	-0.6	-2.1	-0.9
Diabetes (father)	1.0	1.2	2.4	-1.5	-1.5	-1.0	-0.7	-0.7	0.5	-1.6	-0.5	-1.6	-0.9
Serious illness, injury or assault to yourself	1.0	1.2	3.4	-0.6	-0.8	-1.1	-1.4	-1.3	-1.0	-0.9	0.6	-0.7	-1.9
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	7.3	0.7	2.7	2.6	0.1	0.8	-0.3	1.9	1.2	1.1	0.7
Leg fat percentage (right)	1.0	3.7	12.0	-2.4	0.4	0.1	2.3	2.4	3.5	1.1	-0.4	-0.6	2.5
Pulse wave peak to peak time	1.0	1.1	6.2	0.9	1.4	0.8	0.4	0.9	-0.0	-0.4	0.8	2.5	-0.4
Medication for pain relief, constipation, heartburn	1.0	1.8	7.5	2.3	1.0	1.4	0.3	0.7	0.4	1.0	-0.2	2.7	-0.3
Medication: Blood pressure	1.0	1.7	4.9	-1.5	-1.2	-1.0	0.9	0.6	0.6	-1.5	-1.8	-0.8	2.2
Medication: Omeprazole	1.0	1.2	4.0	-0.6	-1.3	-1.6	0.0	-0.7	-0.3	-1.2	-2.0	-1.1	0.5
Leg fat mass (right)	1.0	3.9	11.9	-1.1	1.8	1.0	2.3	2.6	3.5	1.4	0.9	0.9	2.5
Number of full sisters	1.0	1.2	3.6	0.6	0.6	0.7	1.1	1.6	1.9	0.7	-0.3	0.9	1.6
Commuting to job workplace: Car/motor vehicle	1.0	1.2	4.7	-0.0	1.5	1.3	0.6	0.6	0.7	1.3	2.2	-0.1	0.4
Illnesses of father: Heart disease	1.0	1.4	4.1	-0.6	-0.7	-1.6	-1.4	-1.3	0.0	-1.5	0.8	-2.0	-0.5
Illnesses of siblings: Diabetes	1.0	1.2	2.9	-1.7	-0.0	-0.7	0.8	0.9	1.3	-0.7	-1.3	-0.3	1.6
Smoking status: Previous	1.0	1.4	2.7	-1.6	-1.2	-0.8	1.6	0.6	-0.4	-1.1	-1.1	-1.4	1.4
Loneliness, isolation	1.0	1.4	4.9	-0.9	0.0	0.5	1.6	1.4	-0.9	-0.5	-1.7	-0.2	2.2
Guilty feelings	1.0	1.5	4.9	-0.7	0.8	1.3	1.3	2.0	0.9	-0.6	-0.3	0.4	2.2
Medication: Bendroflumethiazide	1.0	1.6	3.2	-0.8	-1.6	-1.8	0.7	0.0	0.2	-1.4	-1.8	-0.9	1.7
Medication: Metformin	0.9	1.3	6.8	-0.6	-0.2	0.1	0.3	1.2	2.6	-0.1	-1.4	-0.3	1.6
High blood pressure	0.9	2.5	8.8	-0.8	-1.4	-1.0	2.5	1.7	1.1	-0.9	-1.1	-0.5	3.0
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	2.8	-0.7	0.8	1.6	1.7	1.6	-0.2	1.2	-0.9	0.2	0.9
Pulse wave Arterial Stiffness index	0.9	1.0	5.5	-0.7	-1.3	-0.8	-0.4	-0.9	-0.0	0.2	-0.7	-2.4	0.3
Arm fat mass (right)	0.9	3.6	10.7	-0.8	1.7	1.0	2.2	2.5	3.3	1.5	1.1	1.2	2.2
Birth weight	0.9	1.9	6.5	-0.4	-0.2	0.1	-2.2	-1.9	-2.5	0.0	0.5	-0.5	-1.8
Number of children fathered	0.9	1.1	2.1	-1.2	-0.6	-0.7	1.4	1.4	-1.0	0.0	-0.8	-1.2	1.1
Hypertension (Self-reported)	0.9	2.4	7.8	-1.1	-1.7	-1.5	1.9	1.3	0.6	-1.4	-1.5	-0.7	2.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	4.0	0.4	-0.6	-0.8	1.4	0.9	0.3	-0.4	-2.0	-0.8	1.3
Qualifications: nursing, teaching	0.9	1.4	3.6	-0.9	-0.9	-1.6	-1.2	-1.3	-1.9	-0.7	-0.6	-0.3	-1.6
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	3.5	-0.6	-1.6	-1.9	-0.6	-1.1	-1.1	-1.0	-0.5	-1.5	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	2.5	-1.6	-0.9	-1.5	0.9	0.0	-0.7	-1.1	-0.6	-1.2	0.6
Medication: Aspirin	0.9	1.1	3.1	-1.6	-0.5	-1.8	0.6	-0.0	0.5	-0.5	-1.2	-1.4	1.0
Medication: Gliclazide	0.9	1.0	2.8	-1.2	-0.4	-0.9	-0.6	-0.4	-1.3	-1.7	-0.8	-1.5	-0.1
Commuting to job workplace: Public transport	0.9	1.1	3.5	-1.3	-0.9	-1.7	-0.6	-0.8	0.2	-1.1	-1.9	-0.1	-0.1
Risk taking	0.9	1.4	3.5	-1.4	0.1	1.6	1.9	1.4	0.5	-0.2	-1.6	0.6	0.9
Ever depressed for a whole week	0.9	1.1	2.6	1.6	-0.3	-0.6	-1.0	-1.2	-1.5	1.2	0.1	-0.6	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	2.5	-0.6	-1.4	-1.6	0.0	-0.6	-0.6	-1.0	-1.5	-1.4	0.4
BMI	0.8	4.7	14.9	-1.2	2.0	0.5	2.0	2.6	3.9	0.4	1.8	0.4	3.4
Respiratory disease	0.8	1.7	4.0	-2.0	-1.8	-1.0	0.1	0.4	-0.6	-1.0	-1.8	-2.0	0.1
Medication for hormone replacement therapy	0.8	0.9	2.3	0.4	1.3	1.5	0.9	0.5	-0.9	-0.4	-0.9	0.7	1.0
Body mass index (BMI)	0.8	3.5	13.3	-0.9	1.5	0.3	1.8	2.2	3.6	1.2	1.0	1.1	2.6
Falls in the last year	0.8	1.1	3.5	0.4	1.9	0.8	0.9	1.8	0.5	0.8	0.0	1.0	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.1	0.7	1.3	1.4	-0.6	-0.3	-0.0	0.8	1.4	1.1	-1.0
Medication: Paracetamol	0.8	1.3	7.9	-2.8	-0.9	-0.1	-0.1	-0.2	-1.0	-0.3	1.1	-1.5	0.1
Pulse rate, automated reading	0.8	2.6	9.6	-1.2	-1.2	-0.0	3.1	2.2	1.2	-0.9	-0.7	0.9	2.1
Ever taken oral contraceptive pill	0.8	0.9	2.3	-0.5	1.4	1.2	0.0	-0.2	0.3	0.6	1.5	1.4	-0.6
Hearing aid user	0.8	0.9	2.2	0.2	-0.9	-1.5	-1.1	-1.1	-0.4	-1.5	0.3	-1.0	-0.2
Vascular/heart problems diagnosed by doctor	0.8	2.2	6.3	1.3	1.8	1.5	-1.6	-1.0	-0.6	1.2	0.9	1.4	-2.5
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	2.8	1.7	-0.3	-1.0	-1.5	-1.6	0.6	0.1	1.2	-0.4	-0.4
Depression (Nagel 2018)	0.7	1.0	4.6	-0.9	0.0	-0.3	1.2	1.4	-0.1	-0.9	0.4	0.4	2.1
Verbal and Numeric Reasoning (VNR)	0.7	1.6	5.0	1.9	0.7	1.2	0.1	0.5	1.9	0.7	1.1	2.2	0.4
Average weekly spirits intake	0.7	0.9	3.2	-0.9	0.8	0.8	0.5	1.4	1.8	1.2	-0.5	-0.1	-0.0
Stomach or abdominal pain in last month	0.7	0.8	2.3	0.8	1.5	1.5	0.6	0.9	-0.7	0.5	-0.2	1.2	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.4	-1.4	-0.4	0.0	1.1	0.8	-0.1	-1.2	0.7	-1.4	1.5
Medication: Simvastatin	0.7	1.0	2.1	-1.5	-1.1	-1.1	-0.0	0.4	1.0	-1.0	-1.0	-1.0	1.1
Mouth/teeth dental problems: Dentures	0.7	1.2	4.5	-0.5	-1.4	-0.9	-0.9	-1.2	0.1	-1.1	-0.8	-2.1	-0.3
Illnesses of mother	0.7	0.9	2.1	1.0	0.9	0.7	1.2	1.5	0.3	0.7	-0.9	1.1	0.8
Blood clot in the leg (DVT)	0.7	1.0	2.9	1.7	-0.0	-1.0	-1.4	-1.3	0.7	0.2	1.2	-0.3	-0.2
Headache pain in last month	0.7	1.3	8.6	-2.9	0.2	-0.3	0.8	0.7	-0.7	-0.3	0.6	-0.5	1.3
Age at first live birth	0.7	1.3	4.0	0.3	-0.4	-1.0	-1.4	-2.0	0.7	-1.3	0.2	-0.5	-1.8
Whole body fat mass	0.7	2.9	8.4	-1.2	1.4	0.9	2.1	2.3	2.9	1.3	0.7	0.7	2.1
Alcohol intake frequency.	0.7	1.7	5.7	0.2	0.3	0.1	-2.1	-2.4	-0.2	0.1	1.7	0.4	-2.0
Comparative height size at age 10	0.7	3.9	10.0	1.2	2.9	2.4	1.1	2.3	-0.3	1.5	3.2	2.1	0.1
Overall health rating	0.7	1.5	7.8	-2.8	-0.6	-0.8	-0.8	-0.1	-1.0	-0.8	-0.6	-2.0	0.1
Family relationship satisfaction	0.7	0.9	3.5	1.5	1.3	0.2	0.5	0.5	0.6	0.7	0.2	1.9	0.5
Diabetes diagnosed by doctor	0.7	1.2	3.3	-1.2	-0.2	-1.2	0.1	0.3	1.8	-0.7	-1.8	-0.8	1.3
Breast cancer (self-reported)	0.7	0.9	1.5	-0.1	-1.2	-1.0	-0.9	-0.4	-1.2	-1.1	0.8	-1.0	-0.9
Arm fat mass (left)	0.7	2.9	8.6	-0.9	1.3	0.6	2.1	2.3	2.9	1.2	0.8	0.9	2.2
Pain type(s) experienced in last month: Hip pain	0.7	0.8	2.1	-1.2	-1.0	-0.8	1.0	0.5	0.4	-0.4	0.2	-1.0	1.5
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.7	-0.5	-1.0	-0.6	-1.0	-1.5	0.4	-0.2	0.4	-1.6	-0.8
Worry (Nagel 2018)	0.6	1.2	3.6	-0.8	-0.8	-0.2	1.1	0.9	-1.0	-1.9	-1.1	-1.5	1.0
Irritable Bowel Disease (IBD)	0.6	1.3	3.5	1.8	1.5	1.9	-0.1	0.4	-0.1	1.3	-0.3	1.1	-1.0
Type 2 Diabetes (T2D) (2012)	0.6	0.7	2.3	0.4	-0.4	-0.2	-0.9	-0.9	1.5	-0.4	-0.6	-1.3	-0.7
Height	0.6	11.4	21.0	2.8	3.5	4.3	4.3	4.6	-2.5	1.0	1.5	4.1	2.9
Smoking Status	0.6	1.3	4.7	-1.4	-2.2	-0.9	0.4	-0.3	-0.2	-1.4	-0.7	-1.8	0.3
Neuroticism	0.6	1.4	4.7	-1.5	-0.3	0.1	1.5	1.5	0.2	-0.8	-0.7	-1.3	2.2
Sensitivity / hurt feelings	0.6	1.0	3.9	-1.3	0.6	0.4	0.5	0.9	1.5	-0.1	-0.7	-0.8	2.0
Systolic blood pressure, automated reading	0.6	1.7	11.0	0.9	0.1	0.2	0.7	1.2	3.3	0.8	-0.4	0.6	1.4
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.5	0.4	0.6	1.2	0.7	1.1	1.6	0.1	-0.0	0.8	0.4
Impedance of leg (right)	0.6	3.1	9.1	-2.2	-2.3	-0.6	-0.9	-1.4	-1.6	-0.9	-1.8	-3.0	-1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.6	-1.4	-0.5	-0.3	1.1	1.0	-0.7	-0.4	-0.2	0.4	1.6
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.4	-0.1	0.3	-0.6	0.4	0.7	-1.6	0.7	-1.4	0.6	0.3
Past tobacco smoking	0.6	1.0	3.3	0.6	1.0	0.2	-1.8	-1.0	0.3	0.7	1.1	0.9	-1.5
Diabetes (self-reported)	0.6	0.9	3.4	-0.6	0.3	-0.3	0.5	0.6	1.9	0.2	-1.3	-0.1	1.5
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	3.2	-0.5	-0.9	-1.8	-1.0	-1.3	-0.7	-1.1	0.3	-0.9	-0.4
Standing height	0.6	5.7	10.9	3.2	2.9	3.3	2.1	2.2	-1.8	0.9	2.1	3.1	0.6
Body fat percentage	0.6	2.4	8.1	-2.6	-0.2	-0.5	1.5	1.6	2.8	0.3	-0.7	-1.0	1.7
Comparative body size at age 10	0.6	1.6	3.3	0.7	1.6	1.0	0.7	1.8	1.5	1.4	1.0	1.5	0.7
Qualifications: College or University degree	0.6	1.9	7.4	2.0	1.6	1.3	-0.1	0.1	-0.3	0.4	-1.2	2.7	-1.3
Leg pain on walking	0.6	0.8	2.1	-0.7	-0.2	-1.4	1.1	0.7	-0.3	-0.3	0.2	-1.4	1.1
Eye problems/disorders: Cataract	0.6	0.7	1.6	-1.2	-0.7	-1.0	-1.0	-0.8	0.4	-1.1	-0.1	-1.0	-0.2
Back pain experienced in last month	0.6	0.9	3.9	1.5	0.0	0.3	0.2	0.2	2.0	1.0	0.8	0.0	0.7
Average weekly champagne plus white wine intake	0.6	0.8	1.8	-0.4	0.4	-0.1	-1.3	-1.2	-1.3	-0.6	1.1	-0.4	-0.9
Medication: Paracetamol	0.6	0.9	5.4	-2.3	-1.1	-0.6	-0.1	-0.4	-0.5	-0.4	0.7	-1.1	0.1
Alcohol drinker status: Never	0.6	0.7	1.7	0.9	0.9	0.4	-1.1	-0.8	-0.2	0.8	1.3	0.9	0.1
Ever smoked	0.6	1.0	4.4	0.7	-0.1	0.8	2.1	1.5	-0.4	0.2	-1.0	0.3	1.0
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.2	-1.0	-0.8	-1.1	0.9	0.3	-0.9	-0.3	-0.8	0.5	1.0
Alzheimer’s Disease (in mother)	0.5	0.5	1.4	-0.2	0.2	0.9	-0.5	-0.1	0.9	1.1	1.2	-0.3	-0.8
Bipolar Disorder (2011)	0.5	0.4	1.1	-0.4	0.1	-0.4	-0.8	-1.1	-0.8	-0.9	-0.2	0.5	-0.7
HbA1C	0.5	0.5	1.8	1.4	0.9	0.4	0.7	0.7	-0.2	0.9	-0.8	0.5	0.5
Neuroticism (2016)	0.5	0.7	2.9	-1.7	-0.2	-0.4	-0.2	-0.1	0.0	-0.6	-0.2	-1.7	0.6
Cardiovascular Disease	0.5	1.5	4.3	-1.5	-1.1	-1.3	1.0	1.1	0.9	-1.2	-0.7	-0.9	2.1
Chronotype (morning person)	0.5	1.2	3.3	1.0	1.0	1.1	1.3	1.8	0.1	1.8	-0.7	0.2	0.3
Hearing difficulty/problems: Yes	0.5	0.8	1.7	-0.9	-0.7	-0.4	1.2	1.1	0.3	0.6	-0.8	-1.1	1.3
Relative age of first facial hair	0.5	1.0	2.2	1.5	0.2	0.2	1.3	0.4	0.9	1.1	-1.0	0.8	1.5
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	1.9	-0.8	0.0	-0.2	-0.7	-1.0	-1.1	0.3	0.6	-0.2	-1.4
Hayfever, allergic rhinitis or eczema	0.5	1.1	3.0	0.7	1.3	1.7	0.7	0.4	-0.9	1.4	0.7	1.4	-0.2
Medication: Levothyroxine sodium	0.5	0.9	4.5	-0.6	-0.0	-1.4	-0.4	-0.8	-0.9	-0.3	-2.1	-0.5	0.7
Impedance of leg (left)	0.5	2.3	7.1	-1.5	-2.1	-0.4	-0.9	-1.1	-1.2	-0.5	-2.0	-2.7	-1.3
Trunk fat mass	0.5	2.0	5.2	-1.4	0.9	0.5	1.9	2.0	2.3	0.6	0.2	0.3	1.9
Financial difficulties in last 2 years	0.5	0.7	3.1	-0.9	0.3	-0.2	0.8	1.0	0.8	-0.3	0.5	0.0	1.8
Medication: Ramipril	0.5	0.6	3.2	0.5	0.4	-0.0	-0.1	1.1	1.8	-0.1	-0.5	0.2	1.1
Fluid intelligence score	0.5	1.1	3.6	-0.1	-1.3	-0.3	-0.8	-0.9	1.9	-1.7	0.2	0.7	-1.1
Illnesses of siblings	0.5	0.7	3.2	0.1	-0.7	-0.3	0.7	0.8	-1.3	-1.8	-0.2	-0.3	0.2
Arm fat percentage (right)	0.5	2.1	8.2	-2.4	-0.2	-0.6	1.2	1.3	2.9	0.5	-0.2	-0.6	1.6
Lung cancer (father)	0.5	0.6	2.3	-1.5	-0.7	-0.0	0.9	0.5	-0.9	0.5	-0.4	0.3	0.7
Length of working week for main job	0.5	0.5	1.6	-0.9	0.1	-0.1	-0.3	-0.2	0.4	-1.0	1.2	-0.5	-1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	3.1	0.3	-0.7	-0.9	-1.3	-1.3	-0.4	-0.1	0.5	-1.8	-0.1
Glaucoma (self-reported)	0.5	0.5	2.7	-0.1	0.9	0.2	-0.1	-0.5	-1.6	-0.2	0.4	1.0	0.7
High blood pressure (siblings)	0.5	0.7	2.4	0.8	0.8	0.1	-0.4	-0.3	1.6	1.5	0.8	0.4	0.6
Wheeze or whistling in the chest in last year	0.5	1.0	2.9	-1.1	-0.6	-0.8	-0.9	-1.1	0.8	-0.9	0.9	-1.7	-0.5
Heart disease (mother)	0.5	0.6	1.5	0.5	0.7	0.2	-1.0	-1.2	0.2	0.8	1.0	0.7	-0.6
Suffer from ‘nerves’	0.5	0.7	2.6	0.0	-0.7	-0.8	-0.9	-0.8	-0.3	-1.6	-0.5	-1.1	-0.7
Had major operations	0.5	0.6	1.6	-0.0	0.1	-0.0	-1.0	-1.3	-1.1	0.9	-0.7	-0.7	-0.8
Medication: Aspirin	0.5	0.7	2.5	-0.7	-0.1	-1.6	0.3	-0.1	0.8	-0.3	-0.8	-1.0	1.1
Arm fat percentage (left)	0.5	2.1	7.0	-2.5	-0.4	-0.9	1.3	1.4	2.6	0.0	-0.7	-0.8	1.6
Average weekly red wine intake	0.5	0.7	2.4	1.4	-0.1	0.2	0.6	0.3	0.6	1.0	-1.6	0.4	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.7	-0.3	-0.4	-0.1	-1.3	-0.8	-0.3	-0.6	0.3	-1.0	-1.1
Illnesses of father: None of the above (group 1)	0.5	0.6	1.2	0.1	0.3	0.9	1.1	0.5	-0.9	0.9	-0.4	1.1	0.5
Eye problems/disorders: Glaucoma	0.5	0.6	2.9	-0.8	-0.2	-0.6	0.7	0.1	-1.7	-0.7	-0.4	0.5	1.0
Medication: Blood pressure	0.5	1.0	2.9	0.5	-0.2	0.4	1.2	1.6	1.7	0.7	-0.6	0.4	1.4
Illnesses of father: High blood pressure	0.5	0.6	1.6	1.2	-0.0	-0.6	1.0	1.1	0.7	-0.4	0.5	0.5	0.7
Irritability	0.5	0.9	2.1	-0.9	-1.3	-0.7	-0.8	-1.2	-0.6	-0.9	-0.4	-1.4	-0.4
Commuting to job workplace: Cycle	0.5	0.6	1.1	-0.1	-0.7	-0.1	-1.0	-1.0	-1.0	-1.0	-0.7	0.3	-0.9
Depressed Affect (Nagel 2018)	0.4	0.9	4.8	-0.5	0.2	0.5	1.3	1.3	-0.0	-0.4	0.1	-0.4	2.2
Neuroticism (Nagel 2018)	0.4	1.0	2.6	-1.2	0.1	0.5	0.9	1.1	-0.4	-1.2	-0.3	-1.3	1.6
Alzheimer’s Disease (including proxy)	0.4	0.5	1.5	-0.5	-0.8	0.2	1.0	1.1	1.2	0.1	-0.3	-0.0	0.8
Blood White Count	0.4	3.3	7.0	-1.6	-2.6	-2.5	-0.5	-1.5	-1.2	-2.4	-0.2	-2.6	0.6
Hypothyroidism (self reported)	0.4	1.0	7.2	-0.5	-0.1	-0.9	-0.3	-0.3	-0.8	0.1	-2.7	-0.8	0.3
Trunk fat percentage	0.4	1.6	5.6	-2.4	-0.4	-0.6	0.9	1.0	2.3	0.0	-0.7	-1.2	1.1
Maternal smoking around birth	0.4	0.6	1.8	-0.2	1.3	1.2	0.1	0.9	-0.1	0.8	0.4	0.9	0.3
Multivitamins +/- minerals	0.4	0.5	1.7	0.2	-0.4	-0.8	-1.3	-1.3	0.2	0.5	0.4	0.1	-1.0
Neuroticism score	0.4	0.8	2.1	-0.9	0.5	1.3	1.0	1.4	0.2	-0.3	0.1	-0.6	1.4
Prospective memory result	0.4	0.5	1.5	-1.2	-0.4	-0.0	1.1	1.0	-0.3	-0.2	-1.0	-0.1	0.3
Peak expiratory flow (PEF)	0.4	0.9	4.3	0.6	0.3	0.0	-1.0	-2.1	0.9	-0.2	0.9	0.6	-1.0
Pulse wave reflection index	0.4	0.5	1.8	0.6	-0.0	-0.5	-1.4	-0.8	-0.0	1.0	0.4	-1.0	-0.4
Ever highly irritable/argumentative for 2 days	0.4	0.4	1.8	-0.2	0.0	0.2	0.6	0.3	-1.2	0.6	1.4	0.0	0.5
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.2	0.2	-0.9	-1.0	-0.2	-0.3	-1.1	-0.7	-0.9	-0.7	-0.5
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	4.3	-0.2	0.1	-1.0	-0.7	-0.8	-0.8	0.2	-2.1	-0.7	0.0
Chronic bronchitis/emphysema (mother)	0.4	0.5	3.8	-1.9	-0.1	-0.6	0.1	0.6	-0.4	-0.1	-0.2	-0.4	-0.1
Exposure to tobacco smoke outside home	0.4	0.5	1.8	-1.0	-0.4	-1.3	-0.8	-0.2	0.3	-0.2	0.3	-0.9	0.1
Number of full brothers	0.4	0.5	1.1	-0.9	0.9	1.0	0.6	1.0	-0.1	0.4	-0.0	0.1	0.8
Shortness of breath walking on level ground	0.4	0.5	1.6	-0.4	-0.2	-0.7	-1.3	-1.1	0.1	-0.4	0.2	-1.1	-0.3
Eye problems/disorders: None of the above	0.4	0.5	1.7	1.3	0.4	0.2	-0.1	0.1	0.6	0.9	0.6	-0.1	-1.0
Medication: Seretide 50 evohaler	0.4	0.5	1.0	-0.4	-0.9	0.9	0.9	0.5	-1.0	0.5	-0.8	-0.5	0.4
Chest pain or discomfort	0.4	0.6	1.6	-1.3	0.3	0.1	-1.2	-0.9	-0.3	-0.0	0.5	-0.9	-0.7
Miserableness	0.4	0.7	2.1	0.5	0.4	0.8	1.1	1.5	0.8	0.3	0.8	-0.1	1.2
Mother’s age at death	0.4	0.5	1.3	0.5	-0.5	-0.9	0.2	-0.3	1.0	-1.1	-0.4	-0.1	0.8
Financial situation satisfaction	0.4	0.5	1.7	0.1	0.4	0.4	-0.5	-0.6	-1.3	0.0	0.8	-0.6	-1.2
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.3	-0.0	0.2	0.9	-0.8	-0.5	-0.5	0.1	0.9	-0.1	-1.2
Average weekly beer plus cider intake	0.4	0.6	2.1	0.1	-1.0	-0.9	0.4	0.8	0.2	-0.8	-1.4	-0.3	1.0
Diastolic blood pressure, automated reading	0.4	1.4	7.0	0.4	-1.0	-0.9	0.7	1.0	2.6	-0.6	0.6	-0.6	1.5
Myopia	0.4	0.6	2.1	0.4	1.0	0.1	-0.6	-1.0	1.4	0.9	0.7	0.6	-0.5
Cholesterol lowering medication	0.4	0.5	2.6	-0.6	-0.7	-0.8	-0.2	0.1	0.6	-0.4	-1.6	-0.9	0.1
Pain experienced in last month	0.4	0.7	1.6	0.5	-1.3	-1.1	-0.6	-0.9	-0.1	-0.2	-1.0	-0.5	-1.2
Basal cell carcinoma (self-reported)	0.4	0.5	1.8	-0.3	0.6	0.1	0.7	1.4	0.0	-0.0	-0.5	0.9	1.1
Intelligence (Savage-Jansen 2018)	0.3	0.8	1.8	1.2	-1.3	-1.3	-0.6	-0.5	0.8	-0.9	-0.8	0.5	-0.5
Schizophrenia (2018)	0.3	0.6	1.7	0.4	-1.3	-1.1	0.4	-0.2	1.1	-0.6	-0.7	-0.9	0.3
Major Depression (MDD)	0.3	0.3	1.5	0.1	-0.4	-0.5	0.4	0.4	0.2	-0.9	-1.2	-0.1	0.5
Age at First Birth	0.3	0.5	1.2	1.0	-0.5	-0.8	-0.3	-0.3	-0.8	-0.8	-1.1	0.3	0.0
LDL Cholesterol	0.3	0.4	1.0	0.7	0.7	1.0	0.5	0.9	-0.1	0.9	0.6	0.0	0.3
Lupus	0.3	0.5	2.1	-1.4	-0.8	-0.7	-0.1	-0.5	0.3	-0.1	-1.0	0.1	0.2
Triglycerides	0.3	0.4	2.3	-0.3	0.1	0.7	-0.5	-0.4	1.5	0.4	0.7	-0.7	0.2
Ulcerative Colitis	0.3	0.4	1.4	0.7	0.6	0.6	-0.8	-0.3	0.0	0.4	0.6	0.2	-1.2
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.8	-1.4	0.2	-0.2	-0.2	0.1	1.7	0.3	-0.9	-0.2	0.6
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.0	-0.7	0.3	0.3	-0.6	0.2	-0.9	-1.0	1.0	0.0	0.2
Ever had hysterectomy (womb removed)	0.3	0.4	1.0	0.4	-0.7	-0.6	-0.0	0.1	-0.8	0.3	-1.0	-0.7	0.8
Diabetes (mother)	0.3	0.4	1.4	-0.3	0.6	0.7	-0.6	-0.5	1.2	0.0	0.5	-0.1	0.9
Pack years adult smoking proportion	0.3	0.5	1.4	-0.9	0.8	1.2	-0.2	0.7	0.2	-0.0	-0.9	-0.5	-0.0
Townsend deprivation index at recruitment	0.3	0.4	1.6	0.6	0.2	-0.2	-0.9	-0.5	1.3	-0.2	0.3	-0.2	-0.6
Fed-up feelings	0.3	0.6	2.8	-1.7	-0.0	0.6	-0.3	0.1	-0.3	-0.7	-0.1	-1.3	0.8
Qualifications: CSEs or equivalent	0.3	0.4	1.5	-0.4	0.3	1.2	-0.5	0.0	0.0	0.6	0.1	-0.2	-1.2
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	1.4	0.2	-0.4	-0.4	0.5	0.3	0.8	0.5	-0.5	-0.3	1.2
High blood pressure (mother)	0.3	0.4	2.2	0.3	-0.8	-0.3	0.1	-0.5	0.7	-1.5	-0.4	0.1	-0.2
Nervous feelings	0.3	0.6	1.2	-0.7	-0.6	0.2	0.8	0.4	-0.7	-1.1	-0.9	-1.0	0.8
Pain all over the body in last month	0.3	0.3	1.1	0.2	-0.5	-0.5	0.6	0.6	0.3	-0.3	-1.1	-0.5	0.7
Father’s age at death	0.3	0.4	1.2	-0.1	-0.3	-0.8	-0.9	-0.8	-0.4	-0.4	0.4	0.3	-1.1
Number of live births	0.3	0.4	3.5	1.9	-0.4	-0.4	-0.2	0.3	0.4	0.3	-0.2	0.3	-0.3
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	2.8	0.7	1.2	1.6	1.1	0.2	-0.2	-0.1	0.7	1.7	0.5
Happiness	0.3	0.4	1.4	1.2	-0.3	-0.6	-0.6	-0.9	0.0	-0.9	0.1	-0.2	-0.6
Noisy workplace	0.3	0.4	1.7	-0.4	-0.5	0.2	0.7	0.2	0.4	0.1	-0.8	-1.3	-0.2
Breastfed as a baby	0.3	0.4	2.5	-0.2	0.1	-0.1	0.3	0.4	-0.7	-0.5	-0.7	-0.1	1.6
Worry too long after embarrassment	0.3	0.5	1.8	-0.2	1.1	1.3	-0.4	-0.0	0.7	0.1	1.1	0.2	-0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.9	0.6	-0.1	0.9	0.5	0.6	0.8	0.5	-0.5	-0.7	0.1
Health satisfaction	0.3	0.4	1.2	-1.1	0.0	-0.8	-0.2	-0.4	-1.1	-0.7	0.0	-0.7	-0.3
Age at last live birth	0.3	0.4	1.0	-0.2	-0.6	-0.3	0.0	-0.7	-0.7	-0.7	-1.0	-0.4	-1.0
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.7	0.5	0.6	0.8	0.3	0.3	-0.5	0.7	-0.7	0.4	-0.6
Ever had bowel cancer screening	0.3	0.3	1.8	1.4	0.3	-0.3	-0.5	-0.5	-0.6	0.7	-0.2	-0.1	0.0
Friendships satisfaction	0.3	0.4	2.5	0.6	0.5	-0.2	-0.0	0.1	1.6	-0.3	0.7	0.5	-0.1
Medication for cholesterol	0.3	0.4	1.6	0.5	0.1	-0.3	-0.7	-0.7	0.3	0.2	1.1	0.1	-1.2
Wears glasses or contact lenses	0.3	0.3	0.8	-0.7	0.4	-0.2	0.4	0.5	-0.3	0.0	-0.9	-0.6	0.7
Pack years of smoking	0.3	0.4	1.8	-0.8	0.6	0.9	-0.2	0.7	0.2	-0.0	-1.3	-0.5	0.2
Bipolar Disorder (2018)	0.2	0.3	0.7	0.4	0.4	-0.5	0.3	-0.1	-0.6	-0.4	-0.5	0.9	0.6
Bipolar Disorder or Schizophrenia	0.2	0.4	1.2	0.6	-0.7	-1.1	0.5	-0.2	0.3	-0.5	-0.9	-0.2	0.6
HDL Cholesterol	0.2	0.3	1.6	1.3	0.1	0.0	-0.0	0.5	-0.8	0.1	0.1	-0.5	0.0
Schizophrenia (2014)	0.2	0.5	1.4	0.4	-0.9	-0.9	-0.4	-0.4	1.1	-0.6	-0.6	-1.2	-0.0
Systolic Blood Pressure	0.2	1.2	11.5	0.1	0.1	0.2	-0.5	0.1	3.4	0.0	0.2	0.2	0.3
Allergy or Eczema	0.2	0.6	1.3	-0.4	0.7	1.0	1.1	0.7	-0.9	0.6	0.8	1.1	0.6
Current tobacco smoking	0.2	0.3	1.0	0.0	-0.5	0.4	0.3	0.9	1.0	-0.0	-0.9	0.1	0.2
Age when periods started (menarche)	0.2	0.4	0.9	0.6	-0.4	0.5	1.0	0.7	-0.4	-0.0	-1.0	0.7	0.1
Number of incorrect matches in round	0.2	0.4	1.1	1.0	0.4	0.6	-0.1	-0.6	0.4	1.1	0.3	0.1	-0.7
Alcohol usually taken with meals	0.2	0.4	1.1	0.1	0.2	0.2	-0.3	-1.0	-0.2	0.8	0.8	0.5	-1.0
Hearing difficulty/problems with background noise	0.2	0.4	1.1	0.1	-0.7	0.1	0.2	0.6	0.7	-0.2	-0.7	-0.9	1.1
Forced vital capacity (FVC)	0.2	0.9	2.8	0.6	0.8	1.7	1.1	0.3	-0.7	-0.0	1.3	1.3	0.3
Worrier / anxious feelings	0.2	0.4	2.0	0.1	0.7	1.4	-0.3	0.7	-0.2	0.6	-0.5	-0.5	0.3
Depression (self-reported)	0.2	0.2	0.9	0.2	-0.1	0.5	0.0	0.5	-0.8	-0.2	0.9	-0.2	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	1.8	0.6	0.9	1.4	0.6	-0.4	0.3	-0.1	0.9	1.4	0.4
Exposure to tobacco smoke at home	0.2	0.2	1.1	-1.0	-0.6	-0.3	-0.1	-0.0	0.6	-0.2	-0.4	-0.3	-0.2
Birth weight of first child	0.2	0.4	0.9	-0.8	-0.6	-1.0	-0.1	-0.5	-1.0	-0.1	0.8	-0.5	-0.2
Gout (self-reported)	0.2	0.2	1.1	-0.4	-0.5	-0.7	0.2	0.3	-0.5	-0.2	-0.1	0.1	1.0
Medication: Allopurinol	0.2	0.2	0.9	-0.1	0.4	0.6	-0.1	0.3	-0.8	-0.2	0.9	-0.1	0.6
Mood swings	0.2	0.3	0.8	-0.8	-0.1	0.9	0.2	0.6	-0.3	-0.3	0.6	-0.6	0.7
Asthma (self-reported)	0.2	0.4	2.0	-0.9	-0.7	-0.3	-0.0	0.3	-0.1	0.2	-1.4	-0.7	0.3
Smoking status: Current	0.2	0.2	0.6	0.1	-0.4	0.7	0.3	0.8	0.6	-0.0	-0.8	0.2	0.0
Ulcerative Colitis (UC)	0.1	0.2	0.7	0.6	0.4	0.4	0.5	0.8	0.0	0.2	-0.0	0.1	0.4
Blood Eosinophil Count	0.1	1.1	6.8	0.8	0.5	0.2	0.7	0.8	0.9	0.2	-2.6	-0.2	1.3
Blood Platelet Count	0.1	1.7	5.3	0.8	0.1	0.3	-1.7	-2.2	1.2	-0.4	2.3	0.1	-1.2
Blood Red Count	0.1	1.0	2.7	1.6	-0.9	-1.0	1.1	0.9	-0.2	-0.2	-0.4	0.9	1.4
Waist Hip Ratio (WHR)	0.1	0.5	2.2	-1.5	-0.4	-0.0	-0.8	-0.8	0.7	0.3	0.1	-0.5	-0.9
Lung FEV1/FVC ratio	0.1	0.4	1.4	-0.5	0.5	0.5	-0.1	-0.8	0.1	-0.7	-1.2	-0.1	-0.7
Lung FVC	0.1	0.5	2.6	-0.3	-1.6	-0.2	0.8	-0.7	0.2	-0.3	-0.7	-0.2	0.2
Tanning	0.1	1.5	3.7	-0.6	-1.5	-1.3	-0.5	-0.9	-1.3	-1.9	-1.8	-1.0	0.0
Allergy	0.1	0.1	1.0	0.3	0.2	0.0	-0.1	0.2	1.0	0.2	-0.1	0.0	0.2
Asthma	0.1	0.2	0.7	-0.6	-0.6	-0.1	-0.3	0.2	-0.1	0.3	-0.8	-0.6	0.2
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.6	0.4	0.1	0.1	0.2	0.0	0.8	0.4	0.5	-0.5	-0.1
Forced vital capacity (FVC), Best measure	0.1	0.4	1.6	0.3	0.3	1.3	0.3	-0.4	-0.4	-0.3	1.1	0.6	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.7	0.0	-0.5	-0.7	0.1	-0.9	0.8	-0.5	0.1	0.3	0.8
Unable to work because of sickness or disability	0.1	0.2	0.5	0.4	-0.0	0.0	-0.3	0.5	-0.4	-0.2	0.7	-0.7	0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.3	4.2	1.9	0.7	1.1	-0.8	0.1	-1.6	2.0	0.3	0.1	-0.8

Hub : Genes

ARHGDIB

Models

Trait associations