Best TWAS P=5.9e-08 · Best GWAS P=1.84e-07 conditioned to 0.44
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | AL133458.1 | 0.29 | 0.00 | enet | 19 | 0.00 | 3.6e-01 | -5.1 | -5.3 | 1.0e-07 | 0.84 | 0.02 | 0.88 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RNASET2 | 0.29 | 0.31 | lasso | 9 | 0.32 | 1.6e-21 | -4.8 | -5.2 | 1.7e-07 | 0.89 | 0.05 | 0.94 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RNASET2 | 0.32 | 0.23 | enet | 48 | 0.24 | 3.3e-20 | -5.1 | -5.4 | 5.9e-08 | 0.90 | 0.02 | 0.98 | TRUE |
| 4 | GTEx | Skin Sun Exposed Lower leg | AL133458.1 | 0.13 | 0.08 | enet | 10 | 0.03 | 1.0e-03 | -5.1 | -5.2 | 2.6e-07 | 0.94 | 0.02 | 0.98 | FALSE |
| 5 | NTR | Blood | RNASET2 | 0.28 | 0.42 | lasso | 13 | 0.43 | 5.3e-155 | -5.1 | -5.2 | 1.8e-07 | 0.98 | 0.02 | 0.98 | FALSE |
| 6 | YFS | Blood | RNASET2 | 0.45 | 0.60 | enet | 24 | 0.61 | 1.8e-260 | -5.1 | -5.1 | 2.9e-07 | 0.98 | 0.02 | 0.98 | FALSE |
| 7 | The Cancer Genome Atlas | Esophageal Carcinoma | RNASET2 | 0.17 | 0.11 | lasso | 3 | 0.09 | 8.7e-04 | -4.8 | -5.2 | 2.0e-07 | 0.89 | 0.02 | 0.93 | FALSE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RNASET2 | 0.05 | 0.03 | lasso | 3 | 0.03 | 9.2e-05 | -5.1 | -5.2 | 1.8e-07 | 0.91 | 0.02 | 0.94 | FALSE |