175 significantly associated models · 38 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 113608257 | 115152814 | 4 | 1 | 4.4e-09 | 2.6e-16 | 2.0e-09 | 46 | BCL2L15 |
2 | 1 | 206559362 | 207773991 | 1 | 1 | 2.0e-07 | 6.2e-06 | 9.5e-02 | 86 | IL24 |
3 | 2 | 102680184 | 103216820 | 1 | 1 | 4.6e-08 | 1.9e-07 | 1.6e-02 | 79 | IL1RL1 |
4 | 3 | 48702606 | 51043528 | 17 | 1 | 2.5e-12 | 2.8e-11 | 4.7e-01 | 99 | MST1R |
5 | 4 | 103091730 | 104503936 | 1 | 1 | 1.4e-07 | 1.5e-07 | 1.3e-06 | 15 | CISD2 |
6 | 6 | 166651581 | 167841508 | 2 | 1 | 5.9e-08 | 1.8e-07 | 4.4e-01 | 98 | RNASET2 |
7 | 9 | 91279481 | 92726464 | 1 | 1 | 1.7e-07 | 2.3e-06 | 2.6e-02 | 78 | SEMA4D |
8 | 10 | 5027660 | 6504126 | 1 | 1 | 2.7e-09 | 1.7e-07 | 1.4e-01 | 92 | FAM208B |
9 | 12 | 111154626 | 113517494 | 3 | 1 | 6.3e-10 | 4.8e-16 | 7.2e-08 | 56 | SH2B3 |
10 | 14 | 74424938 | 76089054 | 3 | 1 | 7.9e-10 | 1.4e-10 | 1.0e+00 | 100 | DLST |
11 | 17 | 37644854 | 39048774 | 2 | 1 | 5.8e-08 | 9.7e-07 | 3.8e-01 | 97 | RAPGEFL1 |
12 | 17 | 47119135 | 47685050 | 1 | 1 | 3.0e-09 | 1.2e-08 | 3.0e-01 | 97 | ZNF652 |
13 | 20 | 30451844 | 30992291 | 1 | 1 | 2.7e-07 | 1.3e-07 | 1.0e+00 | 100 | TM9SF4 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Brain Cerebellar Hemisphere | 4 | 0.269 | 1.7 |
GTEx | Brain Cerebellum | 4 | 0.202 | 1.7 |
GTEx | Breast Mammary Tissue | 3 | 0.152 | 1.7 |
GTEx | Skin Not Sun Exposed Suprapubic | 5 | 0.203 | 1.7 |
GTEx | Skin Sun Exposed Lower leg | 8 | 0.220 | 1.7 |
GTEx | Small Intestine Terminal Ileum | 1 | 0.217 | 1.7 |
GTEx | Adipose Subcutaneous | 2 | 0.057 | 1.6 |
GTEx | Artery Aorta | 3 | 0.101 | 1.6 |
GTEx | Artery Tibial | 5 | 0.133 | 1.6 |
GTEx | Brain Caudate basal ganglia | 2 | 0.217 | 1.6 |
GTEx | Brain Cortex | 2 | 0.193 | 1.6 |
GTEx | Brain Frontal Cortex BA9 | 2 | 0.216 | 1.6 |
GTEx | Cells EBV-transformed lymphocytes | 1 | 0.070 | 1.6 |
GTEx | Cells Transformed fibroblasts | 3 | 0.071 | 1.6 |
GTEx | Colon Transverse | 3 | 0.145 | 1.6 |
GTEx | Esophagus Gastroesophageal Junction | 2 | 0.138 | 1.6 |
GTEx | Esophagus Mucosa | 5 | 0.151 | 1.6 |
GTEx | Esophagus Muscularis | 2 | 0.062 | 1.6 |
GTEx | Heart Atrial Appendage | 3 | 0.190 | 1.6 |
GTEx | Lung | 5 | 0.174 | 1.6 |
GTEx | Muscle Skeletal | 1 | 0.035 | 1.6 |
GTEx | Pancreas | 1 | 0.061 | 1.6 |
GTEx | Pituitary | 1 | 0.090 | 1.6 |
GTEx | Spleen | 3 | 0.213 | 1.6 |
GTEx | Thyroid | 4 | 0.100 | 1.6 |
GTEx | Uterus | 0 | 0.000 | 1.6 |
GTEx | Vagina | 1 | 0.157 | 1.6 |
GTEx | Whole Blood | 2 | 0.100 | 1.6 |
NTR | Blood | 4 | 0.167 | 1.6 |
CommonMind | Brain Pre-frontal Cortex | 5 | 0.093 | 1.6 |
The Cancer Genome Atlas | Esophageal Carcinoma | 1 | 0.146 | 1.6 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 4 | 0.136 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 2 | 0.120 | 1.6 |
GTEx | Adipose Visceral Omentum | 2 | 0.098 | 1.5 |
GTEx | Adrenal Gland | 1 | 0.069 | 1.5 |
GTEx | Artery Coronary | 1 | 0.085 | 1.5 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.5 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.5 |
GTEx | Brain Nucleus accumbens basal ganglia | 2 | 0.231 | 1.5 |
GTEx | Brain Putamen basal ganglia | 1 | 0.160 | 1.5 |
GTEx | Breast Mammary Tissue (Female) | 1 | 0.061 | 1.5 |
GTEx | Colon Sigmoid | 2 | 0.137 | 1.5 |
GTEx | Heart Left Ventricle | 2 | 0.131 | 1.5 |
GTEx | Liver | 1 | 0.139 | 1.5 |
GTEx | Nerve Tibial | 3 | 0.069 | 1.5 |
GTEx | Ovary | 0 | 0.000 | 1.5 |
GTEx | Prostate | 1 | 0.120 | 1.5 |
GTEx | Stomach | 2 | 0.138 | 1.5 |
GTEx | Testis | 4 | 0.127 | 1.5 |
METSIM | Adipose | 3 | 0.065 | 1.5 |
ROSMAP | Brain Pre-frontal Cortex | 5 | 0.114 | 1.5 |
YFS | Blood | 4 | 0.087 | 1.5 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 1 | 0.060 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 5 | 0.113 | 1.5 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 1 | 0.091 | 1.5 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 2 | 0.097 | 1.5 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 2 | 0.196 | 1.5 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 2 | 0.073 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 6 | 0.146 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 3 | 0.146 | 1.5 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 7 | 0.163 | 1.5 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 2 | 0.080 | 1.5 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 3 | 0.065 | 1.5 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 2 | 0.119 | 1.5 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 1 | 0.078 | 1.5 |
The Cancer Genome Atlas | Thyroid Carcinoma | 6 | 0.116 | 1.5 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.5 |
GTEx | Breast Mammary Tissue (Male) | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 1 | 0.090 | 1.4 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 1 | 0.063 | 1.4 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 1 | 0.075 | 1.4 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.4 |