Best TWAS P=2.17e-13 · Best GWAS P=1.49e-12 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | PRPF40A | 0.16 | 0.18 | bslmm | 464 | 0.19 | 1.9e-22 | 6.7 | 7.3 | 2.2e-13 | 0.95 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | PRPF40A | 0.06 | 0.00 | blup | 66 | 0.04 | 9.3e-03 | 6.7 | 6.7 | 2.3e-11 | 0.88 | 0.02 | 0.67 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | PRPF40A | 0.03 | 0.02 | blup | 66 | 0.02 | 5.2e-03 | 6.7 | 6.6 | 3.9e-11 | 0.89 | 0.01 | 0.76 | FALSE |