Best TWAS P=1.78e-08 · Best GWAS P=1.21e-08 conditioned to 0.226
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | EEFSEC | 0.08 | 0.08 | lasso | 2 | 0.06 | 2.4e-05 | 5.6 | -5.6 | 1.8e-08 | -0.94 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Esophagus Muscularis | EEFSEC | 0.07 | 0.08 | lasso | 5 | 0.07 | 4.4e-05 | 5.5 | -5.5 | 4.1e-08 | -0.95 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Muscle Skeletal | EEFSEC | 0.05 | 0.01 | lasso | 5 | 0.02 | 4.3e-03 | 4.3 | -5.2 | 2.1e-07 | -0.86 | 0.06 | 0.92 | FALSE |
| 4 | GTEx | Nerve Tibial | EEFSEC | 0.07 | 0.06 | lasso | 2 | 0.06 | 4.5e-05 | 5.5 | -5.6 | 2.7e-08 | -0.94 | 0.01 | 0.99 | FALSE |