[Hub]/) : Traits : Age when periods started (menarche) : ← →

chr6:56,123,698-57,687,035

Best TWAS P=9.38e-11 · Best GWAS P=1.76e-10 conditioned to 0.418

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	BEND6	0.21	0.30	lasso	6	0.30	2.1e-36	-5.7	6.0	1.5e-09	-0.87	0.06	0.94	FALSE
2	GTEx	Lung	KIAA1586	0.06	0.03	enet	14	0.04	3.4e-04	-6.2	5.3	1.1e-07	-0.81	0.04	0.95	FALSE
3	GTEx	Testis	RP11-203B9.4	0.09	0.03	enet	6	0.08	1.3e-04	-5.9	-6.4	1.3e-10	0.75	0.04	0.82	FALSE
4	ROSMAP	Brain Pre-frontal Cortex	BEND6	0.28	0.36	lasso	4	0.35	1.1e-46	-5.8	6.0	2.7e-09	-0.81	0.05	0.95	FALSE
5	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	BEND6	0.05	0.06	blup	44	0.06	8.9e-06	-6.3	6.2	5.1e-10	-0.92	0.01	0.99	FALSE
6	The Cancer Genome Atlas	Breast Invasive Carcinoma	BEND6	0.05	0.08	blup	44	0.09	6.1e-18	-5.8	6.4	1.8e-10	-0.91	0.03	0.97	FALSE
7	The Cancer Genome Atlas	Colon Adenocarcinoma	BEND6	0.12	0.12	blup	44	0.15	5.7e-09	-6.0	6.0	1.7e-09	-0.90	0.04	0.96	FALSE
8	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	BEND6	0.11	0.10	lasso	3	0.13	1.4e-14	-6.3	6.3	2.3e-10	-0.91	0.01	0.99	FALSE
9	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	BEND6	0.06	0.08	blup	44	0.07	1.7e-08	-5.8	5.8	5.7e-09	-0.83	0.08	0.92	FALSE
10	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	BEND6	0.06	0.04	blup	44	0.05	1.1e-03	-6.0	6.0	2.4e-09	-0.92	0.02	0.96	FALSE
11	The Cancer Genome Atlas	Lung Adenocarcinoma	BEND6	0.07	0.09	lasso	6	0.11	2.0e-12	-5.9	6.3	2.7e-10	-0.92	0.02	0.98	FALSE
12	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	BEND6	0.06	0.06	enet	11	0.09	4.5e-10	-5.7	5.7	9.2e-09	-0.89	0.04	0.96	FALSE
13	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	BEND6	0.19	0.16	lasso	3	0.18	8.3e-08	-6.4	6.5	1.2e-10	-0.99	0.00	0.99	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	BEND6	0.15	0.26	lasso	7	0.29	8.9e-31	-6.2	6.5	9.4e-11	-0.94	0.01	0.99	TRUE
15	The Cancer Genome Atlas	Rectum Adenocarcinoma	BEND6	0.20	0.15	blup	44	0.18	6.4e-05	-5.7	6.4	2.0e-10	-0.92	0.02	0.91	FALSE
16	The Cancer Genome Atlas	Soft Tissue Sarcoma	BEND6	0.09	0.07	lasso	5	0.08	2.9e-05	-5.9	6.2	5.7e-10	-0.83	0.02	0.96	FALSE
17	The Cancer Genome Atlas	Stomach Adenocarcinoma	BEND6	0.07	0.09	enet	5	0.09	8.1e-07	-5.9	5.8	6.8e-09	-0.86	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Testicular Germ Cell Tumors	BEND6	0.08	0.05	blup	44	0.06	4.7e-03	-5.3	5.5	3.2e-08	-0.74	0.05	0.66	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	BEND6	0.10	0.18	blup	44	0.15	2.6e-14	-5.7	5.4	6.2e-08	-0.82	0.04	0.96	FALSE