Best TWAS P=5.4e-09 · Best GWAS P=8.81e-11 conditioned to 0.0024
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | HCRTR2 | 0.05 | 0.03 | lasso | 4 | 0.02 | 1.7e-03 | -5.6 | 5.4 | 6.6e-08 | 0.76 | 0.09 | 0.88 | FALSE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAM83B | 0.04 | 0.02 | blup | 92 | 0.02 | 1.7e-05 | 6.0 | 5.8 | 5.4e-09 | 0.80 | 0.02 | 0.98 | TRUE |