Best TWAS P=2.02e-09 · Best GWAS P=4.71e-08 conditioned to 0.695
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Brain Lower Grade Glioma | METT5D1 | 0.04 | 0.03 | lasso | 2 | 0.03 | 0.00017 | 5.4 | 5.5 | 5.1e-08 | 1.00 | 0.03 | 0.95 | FALSE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | METT5D1 | 0.02 | 0.02 | enet | 6 | 0.02 | 0.00241 | 5.2 | 5.7 | 1.1e-08 | 0.96 | 0.03 | 0.75 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | KIF18A | 0.04 | 0.01 | blup | 69 | 0.03 | 0.00129 | 2.8 | -6.0 | 2.0e-09 | -0.88 | 0.03 | 0.82 | TRUE |