[Hub]/) : Traits : Age when periods started (menarche) :

chr11:42,881,882-44,596,817

Best TWAS P=5.11e-09 · Best GWAS P=1.99e-10 conditioned to 0.000668

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial RP11-613D13.5 0.17 0.18 lasso 6 0.18 2.4e-14 -4.5 5.1 2.9e-07 -0.69 0.86 0.13 FALSE
2 GTEx Brain Caudate basal ganglia RP11-613D13.5 0.32 0.14 enet 24 0.13 1.6e-04 -4.2 5.8 5.1e-09 -0.64 0.24 0.51 TRUE
3 GTEx Esophagus Gastroesophageal Junction HSD17B12 0.51 0.35 lasso 7 0.37 3.1e-14 -4.5 5.2 1.8e-07 -0.73 0.54 0.46 FALSE
4 GTEx Esophagus Muscularis RP11-613D13.5 0.21 0.20 lasso 2 0.19 9.6e-12 -4.5 5.2 2.0e-07 -0.64 0.97 0.03 FALSE
5 GTEx Testis HSD17B12 0.67 0.58 lasso 10 0.60 8.5e-33 -4.5 5.2 2.2e-07 -0.72 0.97 0.03 FALSE
6 ROSMAP Brain Pre-frontal Cortex HSD17B12 0.45 0.37 enet 72 0.47 1.1e-68 -4.5 5.3 1.5e-07 -0.60 0.95 0.04 FALSE