Best TWAS P=1.1e-08 · Best GWAS P=6.93e-08 conditioned to 0.247
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DCXR | 0.14 | 0.07 | enet | 17 | 0.10 | 3.4e-12 | 4.9 | 5.5 | 3.3e-08 | 0.83 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Adrenal Gland | DCXR | 0.38 | 0.18 | lasso | 4 | 0.20 | 1.2e-07 | 5.4 | 5.2 | 1.7e-07 | 0.95 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Tibial | DCXR | 0.28 | 0.21 | lasso | 5 | 0.21 | 3.1e-16 | 5.1 | 5.4 | 6.5e-08 | 0.95 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Brain Cerebellum | DCXR | 0.20 | 0.23 | lasso | 3 | 0.22 | 4.5e-07 | 5.4 | 5.4 | 6.0e-08 | 1.00 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Esophagus Muscularis | DCXR | 0.18 | 0.08 | lasso | 5 | 0.05 | 9.2e-04 | 5.1 | 5.5 | 3.5e-08 | 0.93 | 0.00 | 0.99 | FALSE |
| 6 | GTEx | Skin Not Sun Exposed Suprapubic | DCXR | 0.12 | 0.00 | enet | 13 | 0.00 | 2.3e-01 | 5.4 | 5.6 | 2.7e-08 | 0.72 | 0.01 | 0.92 | FALSE |
| 7 | GTEx | Skin Sun Exposed Lower leg | DCXR | 0.08 | 0.11 | lasso | 7 | 0.09 | 4.6e-08 | 5.4 | 5.4 | 7.7e-08 | 0.96 | 0.00 | 1.00 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | DCXR | 0.09 | 0.03 | blup | 38 | 0.09 | 9.5e-09 | 5.4 | 5.7 | 1.1e-08 | 0.83 | 0.00 | 1.00 | TRUE |