Best TWAS P=8.73e-08 · Best GWAS P=2.61e-11 conditioned to 1.02e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Atrial Appendage | PEMT | 0.22 | 0.08 | lasso | 5 | 0.05 | 3.8e-03 | -5.4 | -5.2 | 2.2e-07 | 0.60 | 0.20 | 0.11 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PEMT | 0.02 | 0.01 | enet | 4 | 0.02 | 5.2e-05 | 3.6 | -5.4 | 8.7e-08 | 0.42 | 0.11 | 0.43 | TRUE |